Comparison of two different measurement methods in evaluating basilar atherosclerotic plaque using high-resolution MRI at 3 tesla

BackgroundTo compare the Self-referenced and Referenced measurement methods in assessing basilar artery (BA) atherosclerotic plaque employing dark blood high-resolution MRI at 3 Tesla.MethodsForty patients with > 20% stenosis as identified by conventional MRA were recruited and evaluated on a 3 Tesla MRI system. The outer wall, inner wall and lumen areas of maximal lumen narrowing site and the outer wall and lumen areas of sites that were proximal and distal to the maximal lumen narrowing site were manually traced. Plaque area (PA), stenosis rate (SR) and percent plaque burden (PPB) were calculated using the Self-referenced and Referenced measurement methods, respectively. To assess intra-observer reproducibility, BA plaque was measured twice with a 2-week interval in between measurements.ResultsThirty-seven patients were included in the final analysis. There were no significant differences in PA, SR and PPB measurements between the two methods. The intra-class coefficients and coefficient of variations (CV) ranged from 0.976 to 0.990 and from 3.73 to 5.61% for the Self-referenced method and ranged from 0.928 to 0.971 and from 4.64 to 9.95% for the Referenced method, respectively. Both methods are effective in the evaluation of BA plaque. However, the CVs of the Self-referenced method is lower than the Referenced measurement method. Moreover, Bland-Altman plots showed that the Self-referenced method has a narrower interval than the Referenced measurement method.ConclusionsThe Self-referenced method is better and more convenient for evaluating BA plaque, and it may serve as a promising method for evaluation of basilar atherosclerotic plaque.

[1]  René M. Botnar,et al.  Characterization of Coronary Atherosclerosis by Magnetic Resonance Imaging , 2013, Circulation.

[2]  Keun-Hwa Jung,et al.  Intracranial plaque enhancement from high resolution vessel wall magnetic resonance imaging predicts stroke recurrence , 2016, International journal of stroke : official journal of the International Stroke Society.

[3]  Craig H Meyer,et al.  Reproducibility and reliability of atherosclerotic plaque volume measurements in peripheral arterial disease with cardiovascular magnetic resonance. , 2007, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[4]  Chun Yuan,et al.  Improved suppression of plaque‐mimicking artifacts in black‐blood carotid atherosclerosis imaging using a multislice motion‐sensitized driven‐equilibrium (MSDE) turbo spin‐echo (TSE) sequence , 2007, Magnetic resonance in medicine.

[5]  Benoit Desjardins,et al.  Rapid High-resolution, Self-registered, Dual Lumen-contrast MRI Method for Vessel-wall Assessment in Peripheral Artery Disease:: A Preliminary Investigation. , 2016, Academic Radiology.

[6]  Chun Yuan,et al.  Multislice double inversion‐recovery black‐blood imaging with simultaneous slice reinversion , 2003, Journal of magnetic resonance imaging : JMRI.

[7]  P. Toutouzas,et al.  A Magnetic Resonance Imaging Study , 2003 .

[8]  A. Beckett,et al.  AKUFO AND IBARAPA. , 1965, Lancet.

[9]  Young-Jun Lee,et al.  The advantage of high-resolution MRI in evaluating basilar plaques: a comparison study with MRA. , 2012, Atherosclerosis.

[10]  Le He,et al.  Characterization of atherosclerotic disease in thoracic aorta: A 3D, multicontrast vessel wall imaging study. , 2016, European journal of radiology.

[11]  Young-Jun Lee,et al.  Basilar plaque on high-resolution MRI predicts progressive motor deficits after pontine infarction. , 2015, Atherosclerosis.

[12]  Chun Yuan,et al.  Efficient flow suppressed MRI improves interscan reproducibility of carotid atherosclerosis plaque burden measurements , 2010, Journal of magnetic resonance imaging : JMRI.

[13]  Jing Huang,et al.  Arterial remodeling of basilar atherosclerosis in isolated pontine infarction , 2015, Neurological Sciences.

[14]  Guoxi Xie,et al.  DANTE‐prepared three‐dimensional FLASH: A fast isotropic‐resolution MR approach to morphological evaluation of the peripheral arterial wall at 3 tesla , 2016, Journal of magnetic resonance imaging : JMRI.

[15]  X. Lou,et al.  Morphologic Characteristics of Atherosclerotic Middle Cerebral Arteries on 3T High-Resolution MRI , 2013, American Journal of Neuroradiology.

[16]  Chun Yuan,et al.  Prevalence and Characteristics of Carotid Artery High‐Risk Atherosclerotic Plaques in Chinese Patients With Cerebrovascular Symptoms: A Chinese Atherosclerosis Risk Evaluation II Study , 2017, Journal of the American Heart Association.

[17]  Soo Mee Lim,et al.  Pattern of atherosclerotic carotid stenosis in Korean patients with stroke: different involvement of intracranial versus extracranial vessels. , 2003, AJNR. American journal of neuroradiology.

[18]  Karla L Miller,et al.  DANTE‐prepared pulse trains: A novel approach to motion‐sensitized and motion‐suppressed quantitative magnetic resonance imaging , 2012, Magnetic resonance in medicine.

[19]  Wenzhen Zhu,et al.  Reproducibility of high-resolution MRI for the middle cerebral artery plaque at 3T. , 2014, European journal of radiology.

[20]  Wan-Qun Yang,et al.  Basilar artery atherosclerotic plaques distribution in symptomatic patients: a 3.0T high-resolution MRI study. , 2013, European journal of radiology.

[21]  J. Fleiss,et al.  Intraclass correlations: uses in assessing rater reliability. , 1979, Psychological bulletin.

[22]  Xihai Zhao,et al.  Association Between Carotid Atherosclerotic Plaque Calcification and Intraplaque Hemorrhage: A Magnetic Resonance Imaging Study , 2017, Arteriosclerosis, thrombosis, and vascular biology.

[23]  Khaled Z. Abd-Elmoniem,et al.  Coronary atherosclerosis and dilation in hyper IgE syndrome patients: Depiction by magnetic resonance vessel wall imaging and pathological correlation. , 2017, Atherosclerosis.

[24]  Aaron Fenster,et al.  Scan-rescan and intra-observer variability of magnetic resonance imaging of carotid atherosclerosis at 1.5 T and 3.0 T. , 2008, Physics in medicine and biology.

[25]  Peter R Luijten,et al.  Detecting Intracranial Vessel Wall Lesions With 7T-Magnetic Resonance Imaging: Patients With Posterior Circulation Ischemia Versus Healthy Controls , 2017, Stroke.

[26]  Chun Yuan,et al.  Carotid Artery Remodeling Is Segment Specific: An In Vivo Study by Vessel Wall Magnetic Resonance Imaging , 2018, Arteriosclerosis, thrombosis, and vascular biology.

[27]  Mark Woodward,et al.  Cross-sectional, prospective study of MRI reproducibility in the assessment of plaque burden of the carotid arteries and aorta. , 2009, Nature clinical practice. Cardiovascular medicine.

[28]  Jiong Cai,et al.  Arterial remodeling of advanced basilar atherosclerosis , 2010, Neurology.

[29]  Eike Nagel,et al.  MR Imaging of Coronary Arteries and Plaques. , 2016, JACC. Cardiovascular imaging.

[30]  Xihai Zhao,et al.  Association of Progression of Carotid Artery Wall Volume and Recurrent Transient Ischemic Attack or Stroke: A Magnetic Resonance Imaging Study , 2018, Stroke.

[31]  Matthew D Robson,et al.  The relationship of perivascular adipose tissue and atherosclerosis in the aorta and carotid arteries, determined by magnetic resonance imaging , 2018, Diabetes & vascular disease research.

[32]  Tao Jiang,et al.  Hyperintense Plaque on Intracranial Vessel Wall Magnetic Resonance Imaging as a Predictor of Artery-to-Artery Embolic Infarction , 2018, Stroke.

[33]  Chun Yuan,et al.  Added Value of Vessel Wall Magnetic Resonance Imaging for Differentiation of Nonocclusive Intracranial Vasculopathies , 2017, Stroke.

[34]  Chun Yuan,et al.  Carotid plaque morphology and composition: initial comparison between 1.5- and 3.0-T magnetic field strengths. , 2008, Radiology.

[35]  Geon-Ho Jahng,et al.  High-Resolution MRI of Intracranial Atherosclerotic Disease , 2014, Neurointervention.

[36]  K. Wong,et al.  Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging , 2017, Journal of stroke.

[37]  Chun Yuan,et al.  Classification of Human Carotid Atherosclerotic Lesions With In Vivo Multicontrast Magnetic Resonance Imaging , 2002, Circulation.

[38]  R L Ehman,et al.  Spatial presaturation: a method for suppressing flow artifacts and improving depiction of vascular anatomy in MR imaging. , 1987, Radiology.

[39]  D. Altman,et al.  STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT , 1986, The Lancet.