Mutations in BMP4 are associated with subepithelial, microform, and overt cleft lip.

[1]  R. Luan,et al.  Association of bone morphogenetic protein 4 gene polymorphisms with nonsyndromic cleft lip with or without cleft palate in Chinese children. , 2008, DNA and cell biology.

[2]  S. Weinberg,et al.  Anatomical Basis for Apparent Subepithelial Cleft Lip: A Histological and Ultrasonographic Survey of the Orbicularis Oris Muscle , 2008, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[3]  M. Dixon,et al.  Facial clefting in Tp63 deficient mice results from altered Bmp4, Fgf8 and Shh signaling. , 2008, Developmental biology.

[4]  C. Ponting,et al.  Mutations in BMP4 cause eye, brain, and digit developmental anomalies: overlap between the BMP4 and hedgehog signaling pathways. , 2008, American journal of human genetics.

[5]  J. Mulliken,et al.  CRISPLD2: a novel NSCLP candidate gene. , 2007, Human molecular genetics.

[6]  B. Maher,et al.  Orbicularis oris muscle defects as an expanded phenotypic feature in nonsyndromic cleft lip with or without cleft palate , 2007, American journal of medical genetics. Part A.

[7]  J. Wallingford,et al.  Mutations in VANGL1 associated with neural-tube defects. , 2007, The New England journal of medicine.

[8]  Shamil R Sunyaev,et al.  Most rare missense alleles are deleterious in humans: implications for complex disease and association studies. , 2007, American journal of human genetics.

[9]  B. Maher,et al.  Impaired FGF signaling contributes to cleft lip and palate , 2007, Proceedings of the National Academy of Sciences.

[10]  A. Palmieri,et al.  Study of the PVRL1 Gene in Italian Nonsyndromic Cleft Lip Patients with or without Cleft Palate , 2006, Annals of human genetics.

[11]  N. Niikawa,et al.  A Mutation in RYK is a Genetic Factor for Nonsyndromic Cleft Lip and Palate , 2006, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[12]  A. Czeizel,et al.  The Pittsburgh Oral-Facial Cleft Study: Expanding the Cleft Phenotype. Background and Justification , 2006, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[13]  M. Marazita,et al.  Contributions of PTCH Gene Variants to Isolated Cleft Lip and Palate , 2006, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[14]  M. Marazita,et al.  Medical Sequencing of Candidate Genes for Nonsyndromic Cleft Lip and Palate , 2005, PLoS genetics.

[15]  R. Schwartz,et al.  Threshold-specific requirements for Bmp4 in mandibular development. , 2005, Developmental biology.

[16]  John A van Aalst,et al.  The spectrum of orofacial clefting. , 2005, Plastic and reconstructive surgery.

[17]  R. Behringer,et al.  Distinct functions for Bmp signaling in lip and palate fusion in mice , 2005, Development.

[18]  K. Christensen,et al.  Interferon regulatory factor 6 (IRF6) gene variants and the risk of isolated cleft lip or palate. , 2004, The New England journal of medicine.

[19]  T. Beaty,et al.  Meta-analysis of 13 genome scans reveals multiple cleft lip/palate genes with novel loci on 9q21 and 2q32-35. , 2004, American journal of human genetics.

[20]  Paul Martin,et al.  Parallels between tissue repair and embryo morphogenesis , 2004, Development.

[21]  Steven Henikoff,et al.  SIFT: predicting amino acid changes that affect protein function , 2003, Nucleic Acids Res..

[22]  K. Christensen,et al.  Complete sequencing shows a role for MSX1 in non-syndromic cleft lip and palate , 2003, Journal of medical genetics.

[23]  P. Bork,et al.  Human non-synonymous SNPs: server and survey. , 2002, Nucleic acids research.

[24]  M. Carstens.  The spectrum of minimal clefting: process-oriented cleft management in the presence of an intact alveolus. , 2000, The Journal of craniofacial surgery (Print).

[25]  F. Beemer,et al.  MSX1 mutation is associated with orofacial clefting and tooth agenesis in humans , 2000, Nature Genetics.

[26]  M A Spence,et al.  Ultrasonographic detection of orbicularis oris defects in first degree relatives of isolated cleft lip patients. , 2000, American journal of medical genetics.

[27]  M. Martinez-frias,et al.  Congenital healed cleft lip. , 1995, American journal of medical genetics.

[28]  K. Benirschke,et al.  Extension of the cleft lip phenotype: the subepithelial cleft. , 1993, American journal of medical genetics.

[29]  Jabaley Me,et al.  The minimal cleft lip revisited: clinical and anatomic correlations. , 1979 .

[30]  Artz Js,et al.  The minimal cleft lip. , 1976 .

[31]  B. Cosman,et al.  THE MINIMAL CLEFT LIP , 1966, Plastic and reconstructive surgery.

[32]  K. Buetow,et al.  Clinical and epidemiologic studies of cleft lip and palate in the Philippines. , 1997, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[33]  M. Jabaley,et al.  The minimal cleft lip revisited: clinical and anatomic correlations. , 1979, The Cleft palate journal.

[34]  Robert J. Gorlin,et al.  Syndromes of the Head and Neck , 1976 .