In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity

[1]  C. Cotman,et al.  Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs. , 1992, The Journal of biological chemistry.

[2]  C. Cotman,et al.  Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures. , 1991, European journal of pharmacology.

[3]  C. Barrow,et al.  Solution structures of beta peptide and its constituent fragments: relation to amyloid deposition. , 1991, Science.

[4]  J. Reed,et al.  Aggregation and secondary structure of synthetic amyloid βA4 peptides of Alzheimer's disease , 1991 .

[5]  D. Selkoe,et al.  Antibodies to non-beta regions of the beta-amyloid precursor protein detect a subset of senile plaques. , 1991, The American journal of pathology.

[6]  S. Ishiura.  Proteolytic Cleavage of the Alzheimer's Disease Amyloid A4 Precursor Protein , 1991 .

[7]  M. Ball,et al.  Beta-amyloid from Alzheimer disease brains inhibits sprouting and survival of sympathetic neurons. , 1991, Biochemical and biophysical research communications.

[8]  C. Cotman,et al.  β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage , 1990, Brain Research.

[9]  B. Yankner,et al.  Nerve growth factor potentiates the neurotoxicity of beta amyloid. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[10]  D. Kirschner,et al.  Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. , 1990, Science.

[11]  T. Oltersdorf,et al.  Cleavage of amyloid beta peptide during constitutive processing of its precursor. , 1990, Science.

[12]  D. Price,et al.  Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing. , 1990, Science.

[13]  C. Cotman,et al.  β-Amyloid protein promotes neuritic branching in hippocampal cultures , 1990, Neuroscience Letters.

[14]  Gregory J. Brewer,et al.  Survival and growth of hippocampal neurons in defined medium at low density: advantages of a sandwich culture technique or low oxygen , 1989, Brain Research.

[15]  L. Villa-komaroff,et al.  Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. , 1989, Science.

[16]  C. Cotman,et al.  Amyloid beta protein enhances the survival of hippocampal neurons in vitro. , 1989, Science.

[17]  C. Cotman,et al.  Senile plaques as aberrant sprout-stimulating structures , 1986, Experimental Neurology.

[18]  C. Masters,et al.  Amyloid plaque core protein in Alzheimer disease and Down syndrome. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[19]  Carl W. Cotman,et al.  The Role of Misdirected Plasticity in Plaque Biogenesis and Alzheimer's Disease Pathology , 1991 .

[20]  C. Marotta,et al.  Identification of cellular and extracellular sites of amyloid precursor protein extracytoplasmic domain in normal and Alzheimer disease brains. , 1989, Proceedings of the National Academy of Sciences of the United States of America.