Early experiences with developing techniques for pure laparoscopic explant hepatectomy in living donor liver transplantation

In recent years, laparoscopic techniques for liver resection or living donor hepatectomy have become common surgical methods. However, reports on laparoscopic surgeries for recipients are lacking. Our center has launched the minimally invasive living donor liver transplantation (LDLT) program in March 2020, which is led by two surgeons who are experienced in laparoscopic surgeries. Recently, we reported our first successful pure laparoscopic recipient explant hepatectomy and the first laparoscopic explant hepatectomy and robotic‐assisted graft implantation. In this article, we introduce a series of minimally invasive surgical cases that were conducted by a single experienced surgeon to share our early experiences leading to our recent successes. We included 10 cases performed from June 2020 to May 2021 in our initial attempt at laparoscopic explant hepatectomy, graft implantation using midline incision, and robotic‐assisted graft implantation surgery. The first four cases required open conversion during the liver mobilization process because of bleeding. The next two cases required open conversion to facilitate portal vein and hepatic artery division. We successfully performed pure laparoscopic explant hepatectomy in the last four cases. For the last case, we attempted to perform graft implantation using a robotic system, but bleeding required open conversion. All patients recovered without any significant acute postoperative problems and were discharged within 2 weeks. All 10 patients were followed up at outpatient clinics, and only one of the 10 patients had a late complication of LDLT. This study has shown that the minimally invasive approach in LDLT may be conducted safely without significant complications if it is performed by highly experienced surgeons working in high‐volume centers.

[1]  J. Bruix,et al.  Reply to: "Correspondence on the ". , 2022, Journal of hepatology.

[2]  Y. Choi,et al.  Laparoscopic donor and recipient hepatectomy followed by robot‐assisted liver graft implantation in living donor liver transplantation , 2021, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[3]  Y. Choi,et al.  Pure laparoscopic living donor liver transplantation: Dreams come true , 2021, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[4]  Y. Choi,et al.  Minimally Invasive Living Donor Liver Transplantation: Pure Laparoscopic Explant Hepatectomy and Graft Implantation Using Upper Midline Incision , 2021, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[5]  Sung‐Gyu Lee,et al.  Long‐Term Safety and Efficacy of Pure Laparoscopic Donor Hepatectomy in Pediatric Living Donor Liver Transplantation , 2020, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[6]  Yajun Chen,et al.  Laparoscopic versus open hepatectomy for elderly patients with hepatocellular carcinoma. , 2020, Journal of B.U.ON. : official journal of the Balkan Union of Oncology.

[7]  K. Suh,et al.  Pure Laparoscopic Versus Open Right Hepatectomy in Live Liver Donors , 2020, Annals of surgery.

[8]  Yoshiharu Nakamura,et al.  The current status of laparoscopic hepatectomy. , 2019, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.

[9]  E. L. Goh,et al.  Laparoscopic vs open hepatectomy for hepatocellular carcinoma in patients with cirrhosis: A meta-analysis of the long-term survival outcomes. , 2018, International journal of surgery.

[10]  K. Suh,et al.  Pure laparoscopic living donor hepatectomy: Focus on 55 donors undergoing right hepatectomy , 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[11]  G. Tsoulfas,et al.  Advances and challenges in laparoscopic surgery in the management of hepatocellular carcinoma , 2017, World journal of gastrointestinal surgery.

[12]  D. Slakey,et al.  Complications of Liver Resection: Laparoscopic Versus Open Procedures , 2013, JSLS : Journal of the Society of Laparoendoscopic Surgeons.

[13]  T. Kanematsu,et al.  Elective living donor liver transplantation by hybrid hand-assisted laparoscopic surgery and short upper midline laparotomy. , 2011, Surgery.

[14]  S. Choi,et al.  High hilar dissection: New technique to reduce biliary complication in living donor liver transplantation , 2004, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[15]  J. Monson,et al.  Evaluation of quality of life after laparoscopic surgery: evidence-based guidelines of the European Association for Endoscopic Surgery , 2004, Surgical Endoscopy.