Renal clearance of pituitary gonadotropins in postmenopausal women.

ABSTRACT The renal clearance of human pituitary gonadotropins (HPG) was studied in 18 normal ambulant postmenopausal subjects and in 32 hospitalized postmenopausal patients suffering from various diseases. Individual values for clearance were low, ranging from 0.04 to 0.43 ml. per minute. When the mean renal clearance in the ambulant group was compared with that in the hospitalized group, no significant difference was found. For both urine and plasma the mean levels of HPG were significantly higher in the ambulant subjects than in the hospitalized patients.