Musician's cramp as manifestation of maladaptive brain plasticity: arguments from instrumental differences

Musician's cramp is a task‐specific movement disorder that presents itself as muscular incoordination or loss of voluntary motor control of extensively trained movements while a musician is playing the instrument. It is characterized by task specificity and gender bias, affecting significantly more males than females. The etiology is multifaceted: a combination of a genetic predisposition, termed endophenotype, and behavioral triggering factors being the leading features for the manifestation of the disorder. We present epidemiological data from 591 musician patients from our outpatient clinic demonstrating an influence of fine‐motor requirements on the manifestation of dystonia. Brass, guitar, and woodwind players were at greater risk than other instrumentalists. High temporospatial precision of movement patterns, synchronous demands on tonic and phasic muscular activation, in combination with fine‐motor burdens of using the dominant hand in daily life activities, constitute as triggering factors for the disorder and may explain why different body parts are affected.

[1]  J. Rothwell,et al.  Motorcortical Excitability and Synaptic Plasticity Is Enhanced in Professional Musicians , 2007, The Journal of Neuroscience.

[2]  E Altenmüller,et al.  Focal dystonia: current theories. , 2001, Human movement science.

[3]  E. Altenmüller Focal dystonia: advances in brain imaging and understanding of fine motor control in musicians. , 2003, Hand clinics.

[4]  B. Rockstroh,et al.  Effective behavioral treatment of focal hand dystonia in musicians alters somatosensory cortical organization , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[5]  A. Fiaschi,et al.  Role of the somatosensory system in primary dystonia , 2003, Movement disorders : official journal of the Movement Disorder Society.

[6]  J. Rothwell,et al.  Pathophysiological differences between musician's dystonia and writer's cramp. , 2005, Brain : a journal of neurology.

[7]  Hans-Christian Jabusch,et al.  Focal dystonia in musicians: Treatment strategies and long‐term outcome in 144 patients , 2005, Movement disorders : official journal of the Movement Disorder Society.

[8]  S. Frucht Embouchure dystonia—Portrait of a task‐specific cranial dystonia , 2009, Movement disorders : official journal of the Movement Disorder Society.

[9]  M. Nicholls,et al.  Perceptual differences in sequential stimuli across patients with musician's and writer's cramp , 2003, Movement disorders : official journal of the Movement Disorder Society.

[10]  E. Altenmüller,et al.  Focal dystonia in musicians: From phenomenology to therapy , 2006 .

[11]  J. Nutt,et al.  Epidemiology of dystonia in Rochester, Minnesota. , 1988, Advances in neurology.

[12]  B. Rockstroh,et al.  Alteration of digital representations in somatosensory cortex in focal hand dystonia , 1998, Neuroreport.

[13]  Hans-Christian Jabusch,et al.  Focal hand dystonia in musicians: phenomenology, etiology, and psychological trigger factors. , 2009, Journal of hand therapy : official journal of the American Society of Hand Therapists.

[14]  E. Altenmüller,et al.  Focal dystonia in musicians: phenomenology, pathophysiology and triggering factors , 2010, European journal of neurology.

[15]  Hans-Christian Jabusch,et al.  Behavioral factors influence the phenotype of musician's dystonia , 2011, Movement disorders : official journal of the Movement Disorder Society.

[16]  Mark Hallett,et al.  Sensory discrimination capabilities in patients with focal hand dystonia , 2000, Annals of neurology.

[17]  S. Pullman,et al.  The hand that has forgotten its cunning—Lessons from musicians' hand dystonia , 2008, Movement disorders : official journal of the Movement Disorder Society.

[18]  E. Altenmüller,et al.  Epidemiology, phenomenology, and therapy of musician's cramp , 2006 .

[19]  B. Rockstroh,et al.  Increased Cortical Representation of the Fingers of the Left Hand in String Players , 1995, Science.

[20]  E. Altenmüller,et al.  The musician's brain as a model of neuroplasticity , 2002, Nature Reviews Neuroscience.

[21]  P. Chamagne,et al.  Prolonged Rehabilitation Treatment of Musician’s Focal Dystonia , 2000 .

[22]  J. Jankovic,et al.  Movement disorders in musicians , 2008, Movement disorders : official journal of the Movement Disorder Society.

[23]  E. Altenmüller,et al.  Musicians' Cramp: Instrumental and Gender Differences , 2003 .

[24]  K. Nakashima,et al.  Prevalence of focal dystonias in the western area of Tottori Prefecture in Japan , 1995, Movement disorders : official journal of the Movement Disorder Society.

[25]  P. Amadio,et al.  Medical Problems of the Instrumentalist Musician , 2000 .