Acyclovir-loaded sulfobutyl ether-β-cyclodextrin decorated chitosan nanodroplets for the local treatment of HSV-2 infections.

[1]  Sherin Varghese,et al.  Chitosan Nanoparticles , 2020, Nanobiotechnology in Diagnosis, Drug Delivery, and Treatment.

[2]  R. Cavalli,et al.  Effect of antibiotic-loaded chitosan nanodroplets on Enterococci isolated from chronic ulcers of the lower limbs. , 2020, Future microbiology.

[3]  P. Mura Advantages of the combined use of cyclodextrins and nanocarriers in drug delivery: a review. , 2020, International journal of pharmaceutics.

[4]  A. Boisen,et al.  Long lasting mucoadhesive membrane based on alginate and chitosan for intravaginal drug delivery , 2020, Journal of Materials Science: Materials in Medicine.

[5]  D. Botezat,et al.  Nanomaterials Designed for Antiviral Drug Delivery Transport across Biological Barriers , 2020, Pharmaceutics.

[6]  Lu Guo,et al.  Ultrasound-responsive highly biocompatible nanodroplets loaded with doxorubicin for tumor imaging and treatment in vivo , 2020, Drug delivery.

[7]  Samuel T. Jones,et al.  Modified cyclodextrins as broad-spectrum antivirals , 2020, Science Advances.

[8]  L. Bedoya,et al.  Vaginal Polyelectrolyte Layer-by-Layer Films Based on Chitosan Derivatives and Eudragit® S100 for pH Responsive Release of Tenofovir , 2020, Marine drugs.

[9]  Synthesis and surface modification of chitosan built nanohydrogel with antiviral and antimicrobial agent for controlled drug delivery , 2019, Biointerface Research in Applied Chemistry.

[10]  M. Zenkova,et al.  A Novel Sulfonated Derivative of β-Cyclodextrin Effectively Inhibits Influenza A Virus Infection in vitro and in vivo , 2019, Acta naturae.

[11]  L. Casettari,et al.  Transmucosal Absorption Enhancers in the Drug Delivery Field , 2019, Pharmaceutics.

[12]  Z. Iqbal,et al.  Nanocarriers for vaginal drug delivery. , 2019, Recent patents on drug delivery & formulation.

[13]  Hairong Zheng,et al.  Echogenic Chitosan Nanodroplets for Spatiotemporally Controlled Gene Delivery. , 2018, Journal of biomedical nanotechnology.

[14]  T. Loftsson,et al.  Solubility of Cyclodextrins and Drug/Cyclodextrin Complexes , 2018, Molecules.

[15]  R. Cavalli,et al.  Acyclovir-Loaded Chitosan Nanospheres from Nano-Emulsion Templating for the Topical Treatment of Herpesviruses Infections , 2018, Pharmaceutics.

[16]  Gajanand Sharma,et al.  Enhanced acyclovir delivery using w/o type microemulsion: preclinical assessment of antiviral activity using murine model of zosteriform cutaneous HSV-1 infection , 2018, Artificial cells, nanomedicine, and biotechnology.

[17]  P. Bąska,et al.  Multifunctional Tannic Acid/Silver Nanoparticle-Based Mucoadhesive Hydrogel for Improved Local Treatment of HSV Infection: In Vitro and In Vivo Studies , 2018, International journal of molecular sciences.

[18]  R. Cavalli,et al.  Nanomedicine formulations for the delivery of antiviral drugs: a promising solution for the treatment of viral infections , 2018, Expert opinion on drug delivery.

[19]  Joshua T Schiffer,et al.  Biologic interactions between HSV-2 and HIV-1 and possible implications for HSV vaccine development. , 2017, Vaccine.

[20]  Gajanand Sharma,et al.  Fabrication of acyclovir-loaded flexible membrane vesicles (FMVs): evidence of preclinical efficacy of antiviral activity in murine model of cutaneous HSV-1 infection , 2017, Drug Delivery and Translational Research.

[21]  A. Luganini,et al.  Vancomycin-loaded nanobubbles: A new platform for controlled antibiotic delivery against methicillin-resistant Staphylococcus aureus infections. , 2017, International journal of pharmaceutics.

[22]  Awanish Kumar,et al.  Why Chitosan? From properties to perspective of mucosal drug delivery. , 2016, International journal of biological macromolecules.

[23]  Wenjing Hu,et al.  Preparation and evaluation of naringenin-loaded sulfobutylether-β-cyclodextrin/chitosan nanoparticles for ocular drug delivery. , 2016, Carbohydrate polymers.

[24]  Yun Ma,et al.  pH and temperature stability of (-)-epigallocatechin-3-gallate-β-cyclodextrin inclusion complex-loaded chitosan nanoparticles. , 2016, Carbohydrate polymers.

[25]  O. Laeyendecker,et al.  Parallel declines in HIV and hepatitis C virus prevalence, but not in herpes simplex virus type 2 infection: A 10-year, serial cross-sectional study in an inner-city emergency department. , 2016, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

[26]  S. Sahin,et al.  Effect of permeability enhancers on paracellular permeability of acyclovir , 2016, The Journal of pharmacy and pharmacology.

[27]  Fei Liu,et al.  Chitosan/sulfobutylether-β-cyclodextrin nanoparticles as a potential approach for tea polyphenol encapsulation , 2016 .

[28]  R. Jayakumar,et al.  Chitosan nanoparticles in drug therapy of infectious and inflammatory diseases , 2016, Expert opinion on drug delivery.

[29]  A. Bernkop‐Schnürch,et al.  Thiolated Cyclodextrin: Development of a Mucoadhesive Vaginal Delivery System for Acyclovir. , 2016, Journal of pharmaceutical sciences.

[30]  M. Pistello,et al.  The AGMA1 poly(amidoamine) inhibits the infectivity of herpes simplex virus in cell lines, in human cervicovaginal histocultures, and in vaginally infected mice. , 2016, Biomaterials.

[31]  Roberta Cavalli,et al.  Nanobubbles: a promising efficient tool for therapeutic delivery. , 2016, Therapeutic delivery.

[32]  A. Balogh,et al.  Formation and stability assessment of self-assembled nanoparticles from large Mw chitosan and sulfobutylether-β-cyclodextrin , 2015 .

[33]  Giuseppina Sandri,et al.  Mucoadhesive and thermogelling systems for vaginal drug delivery. , 2015, Advanced drug delivery reviews.

[34]  Bruno Sarmento,et al.  Polymer-based nanocarriers for vaginal drug delivery. , 2015, Advanced drug delivery reviews.

[35]  F. Otero-Espinar,et al.  Chitosan and Kappa-Carrageenan Vaginal Acyclovir Formulations for Prevention of Genital Herpes. In Vitro and Ex Vivo Evaluation , 2015, Marine drugs.

[36]  Johnny J. He,et al.  Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase. , 2015, Bioorganic & medicinal chemistry letters.

[37]  R. Cavalli,et al.  Chitosan-shelled oxygen-loaded nanodroplets abrogate hypoxia dysregulation of human keratinocyte gelatinases and inhibitors: New insights for chronic wound healing. , 2015, Toxicology and applied pharmacology.

[38]  Tarek A. Ahmed,et al.  Utilization of nanotechnology to enhance percutaneous absorption of acyclovir in the treatment of herpes simplex viral infections , 2015, International journal of nanomedicine.

[39]  R. Cavalli,et al.  Antimicrobial chitosan nanodroplets: new insights for ultrasound-mediated adjuvant treatment of skin infection. , 2015, Future microbiology.

[40]  P. Giustetto,et al.  Preparation and in vitro characterization of chitosan nanobubbles as theranostic agents. , 2015, Colloids and surfaces. B, Biointerfaces.

[41]  M. Attimarad,et al.  Enhanced oral bioavailability of acyclovir by inclusion complex using hydroxypropyl-β-cyclodextrin , 2014, Drug delivery.

[42]  Meenakshi Dhanawat,et al.  Vaginal drug delivery: strategies and concerns in polymeric nanoparticle development , 2014, Expert opinion on drug delivery.

[43]  L. Stanberry,et al.  Current thinking on genital herpes , 2014, Current opinion in infectious diseases.

[44]  Linda Pastero,et al.  Encapsulation of Acyclovir in new carboxylated cyclodextrin-based nanosponges improves the agent's antiviral efficacy. , 2013, International journal of pharmaceutics.

[45]  M. Trotta,et al.  New chitosan nanobubbles for ultrasound-mediated gene delivery: preparation and in vitro characterization , 2012, International journal of nanomedicine.

[46]  P. Mura,et al.  Improvement of oxaprozin solubility and permeability by the combined use of cyclodextrin, chitosan, and bile components. , 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[47]  A. Wald,et al.  Genital herpes , 2008, The Lancet.

[48]  John G Beauman Genital herpes: a review. , 2005, American family physician.

[49]  S. Rossi,et al.  Assessment of chitosan derivatives as buccal and vaginal penetration enhancers. , 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[50]  J. Nishijo,et al.  Interactions of cholesterol with cyclodextrins in aqueous solution. , 2003, Chemical & pharmaceutical bulletin.

[51]  T. Kurimura,et al.  Characterization of Human Immunodeficiency Virus Type 1 Resistant to Modified Cyclodextrin Sulphate (mCDS71) in Vitro , 1999, Antiviral chemistry & chemotherapy.

[52]  H. Mori,et al.  A new candidate for an anti-HIV-1 agent: modified cyclodextrin sulfate (mCDS71). , 1993, Journal of medicinal chemistry.

[53]  D. Campoli-Richards,et al.  Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy. , 1989, Drugs.

[54]  E. B. Turner,et al.  Efficacy of topical acyclovir cream in first and recurrent episodes of genital herpes. , 1983, Antiviral research.

[55]  Pierre P. D. Kondiah,et al.  Development of a Novel Polymeric Nanocomposite Complex for Drugs with Low Bioavailability , 2017, AAPS PharmSciTech.

[56]  R. Cavalli,et al.  Enhanced antiviral activity of acyclovir loaded into nanoparticles. , 2012, Methods in enzymology.

[57]  T. Higuchi,et al.  Phase solubility techniques , 1965 .