Rats preexposed to MDMA display attenuated responses to its aversive effects in the absence of persistent monoamine depletions

[1]  Richard J. Wise,et al.  Drug seeking in response to a priming injection of MDMA in rats: relationship to initial sensitivity to self-administered MDMA and dorsal striatal dopamine. , 2010, The international journal of neuropsychopharmacology.

[2]  B. Ross The Psychology of Learning and Motivation: Advances in Research and Theory , 2010 .

[3]  C. Duvauchelle,et al.  Behavioral, thermal and neurochemical effects of acute and chronic 3,4-methylenedioxymethamphetamine (“Ecstasy”) self-administration , 2010, Behavioural Brain Research.

[4]  J. Sanchez-Ramos,et al.  Effects of MDMA ("ecstasy") during adolescence on place conditioning and hippocampal neurogenesis. , 2010, European journal of pharmacology.

[5]  S. Schenk,et al.  Acute and sensitized response to 3,4‐methylenedioxymethamphetamine in rats: different behavioral profiles reflected in different patterns of Fos expression , 2008, The European journal of neuroscience.

[6]  D. Gittings,et al.  Effects of priming injections of MDMA and cocaine on reinstatement of MDMA- and cocaine-seeking in rats. , 2008, Drug and alcohol dependence.

[7]  L. Cottler,et al.  Ecstasy and other club drugs: a review of recent epidemiologic studies , 2008, Current opinion in psychiatry.

[8]  Cullen B. Owens,et al.  Dissociation of the Neurochemical and Behavioral Toxicology of MDMA (‘Ecstasy’) by Citalopram , 2008, Neuropsychopharmacology.

[9]  Peter G. Roma,et al.  The effects of nicotine on ethanol-induced conditioned taste aversions in Long–Evans rats , 2008, Psychopharmacology.

[10]  Danielle L. Graham,et al.  The effects of continuous and intermittent ethanol exposure in adolesence on the aversive properties of ethanol during adulthood. , 2007, Alcoholism, clinical and experimental research.

[11]  A. Riley,et al.  The effects of cocaine preexposure on cocaine-induced taste aversion learning in Fischer and Lewis rat strains , 2007, Pharmacology Biochemistry and Behavior.

[12]  T. Robbins,et al.  Enduring Deficits in Sustained Visual Attention during Withdrawal of Intravenous Methylenedioxymethamphetamine Self-Administration in Rats: Results from a Comparative Study with d-Amphetamine and Methamphetamine , 2007, Neuropsychopharmacology.

[13]  J. Fisk,et al.  Information processing speed in ecstasy (MDMA) users , 2007, Human psychopharmacology.

[14]  E. Wish,et al.  Evidence for Significant Polydrug Use Among Ecstasy-Using College Students , 2006, Journal of American college health : J of ACH.

[15]  B. Piper,et al.  Repeated Adolescent 3,4-Methylenedioxymethamphetamine (MDMA) Exposure in Rats Attenuates the Effects of a Subsequent Challenge with MDMA or a 5-Hydroxytryptamine1A Receptor Agonist , 2006, Journal of Pharmacology and Experimental Therapeutics.

[16]  M. Shram,et al.  Periadolescent and adult rats respond differently in tests measuring the rewarding and aversive effects of nicotine , 2006, Psychopharmacology.

[17]  Michael H. Baumann,et al.  3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings , 2006, Psychopharmacology.

[18]  R. Verkes,et al.  A review of acute effects of 3,4-methylenedioxymethamphetamine in healthy volunteers , 2006, Journal of psychopharmacology.

[19]  B. Piper,et al.  Repeated MDMA ("Ecstasy") exposure in adolescent male rats alters temperature regulation, spontaneous motor activity, attention, and serotonin transporter binding. , 2005, Developmental psychobiology.

[20]  A. Riley,et al.  Morphine preexposure facilitates morphine place preference and attenuates morphine taste aversion , 2005, Pharmacology Biochemistry and Behavior.

[21]  A. Parrott Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or Ecstasy , 2005, Journal of psychopharmacology.

[22]  J. Fisk,et al.  Evidence for executive deficits among users of MDMA (Ecstasy). , 2004, British journal of psychology.

[23]  G. Ricaurte,et al.  Behavioral and Neurochemical Consequences of Long-Term Intravenous Self-Administration of MDMA and Its Enantiomers by Rhesus Monkeys , 2004, Neuropsychopharmacology.

[24]  H. Curran,et al.  Acute, sub‐acute and long‐term subjective consequences of ‘ecstasy’ (MDMA) consumption in 430 regular users , 2003, Human psychopharmacology.

[25]  Division on Earth Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research , 2003 .

[26]  Felisa González,et al.  The Role of Injection Cues in the Associative Control of the US Pre-Exposure Effect in Flavour Aversion Learning , 2003, The Quarterly journal of experimental psychology. B, Comparative and physiological psychology.

[27]  D. Gittings,et al.  Development, maintenance and temporal pattern of self-administration maintained by ecstasy (MDMA) in rats , 2003, Psychopharmacology.

[28]  J. Cadet,et al.  Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms , 2003, Brain Research Reviews.

[29]  T. Ullrich,et al.  3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") and its stereoisomers as reinforcers in rhesus monkeys: serotonergic involvement , 2002, Psychopharmacology.

[30]  V. Curran,et al.  Sub-acute effects of MDMA (±3,4-methylenedioxymethamphetamine, "ecstasy") on mood: evidence of gender differences , 2002, Psychopharmacology.

[31]  J. Swettenham,et al.  Long-term changes in social interaction and reward following repeated MDMA administration to adolescent rats without accompanying serotonergic neurotoxicity , 2002, Psychopharmacology.

[32]  P. Fletcher,et al.  Pre-Exposure to (±)3,4-methylenedioxy-methamphetamine (MDMA) Facilitates Acquisition of Intravenous Cocaine Self-Administration in Rats , 2001, Neuropsychopharmacology.

[33]  M. Carroll,et al.  Regulation of drug intake. , 2001, Experimental and clinical psychopharmacology.

[34]  A. Saria,et al.  Reinforcing Effects of MDMA (‘Ecstasy’) in Drug-Naive and Cocaine-Trained Rats , 2001, Pharmacology.

[35]  S. Klein,et al.  Handbook of contemporary learning theories , 2000 .

[36]  M. Shankaran,et al.  A neurotoxic regimen of MDMA suppresses behavioral, thermal and neurochemical responses to subsequent MDMA administration , 1999, Psychopharmacology.

[37]  A. Riley,et al.  Cocaine Preexposure Fails to Sensitize the Acquisition of Cocaine-Induced Taste Aversions , 1999, Pharmacology Biochemistry and Behavior.

[38]  S. Butcher,et al.  Behavioural analysis of the acute and chronic effects of MDMA treatment in the rat , 1999, Psychopharmacology.

[39]  R. Rothman,et al.  Functional Consequences of Central Serotonin Depletion Produced by Repeated Fenfluramine Administration in Rats , 1998, The Journal of Neuroscience.

[40]  F. Schifano,et al.  MDMA ('ecstasy') consumption in the context of polydrug abuse: a report on 150 patients. , 1998, Drug and alcohol dependence.

[41]  M. Colado,et al.  The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (`ecstasy') , 1998, Neuropharmacology.

[42]  P. Kalivas,et al.  MDMA Elicits Behavioral and Neurochemical Sensitization in Rats , 1998, Neuropsychopharmacology.

[43]  A. Riley,et al.  The Effects of Cocaine Preexposure on the Acquisition of Cocaine-Induced Taste Aversions , 1998, Pharmacology Biochemistry and Behavior.

[44]  P. S. Grigson Conditioned taste aversions and drugs of abuse: a reinterpretation. , 1997, Behavioral neuroscience.

[45]  Andrew N. Rowan Guide for the Care and Use of Laboratory Animals , 1996 .

[46]  R. Dafters Hyperthermia following MDMA administration in rats: Effects of ambient temperature, water consumption, and chronic dosing , 1995, Physiology & Behavior.

[47]  W. Slikker,et al.  Behavioral and neurochemical effects of chronic methylenedioxymethamphetamine (MDMA) treatment in rhesus monkeys. , 1995, Neurotoxicology and teratology.

[48]  L. Parker Rewarding drugs produce taste avoidance, but not taste aversion , 1995, Neuroscience & Biobehavioral Reviews.

[49]  D. Jackson,et al.  Constrasting effects of dopaminergic blockade on MDMA and d-amphetamine conditioned taste aversions , 1994, Pharmacology Biochemistry and Behavior.

[50]  D. Jackson,et al.  Comparison of conditioned taste aversions produced by MDMA and d-amphetamine , 1993, Pharmacology Biochemistry and Behavior.

[51]  M. Geyer,et al.  Tolerance and cross-tolerance to the activating effects of 3,4-methylenedioxymethamphetamine and a 5-hydroxytryptamine1B agonist. , 1992, The Journal of pharmacology and experimental therapeutics.

[52]  B. Yamamoto,et al.  Acute and subchronic effects of methylenedioxymethamphetamine [(±)MDMA] on locomotion and serotonin syndrome behavior in the rat , 1989, Pharmacology Biochemistry and Behavior.

[53]  G. Battaglia,et al.  Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[54]  E. D. De Souza,et al.  3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites. , 1987, The Journal of pharmacology and experimental therapeutics.

[55]  Z. Amit,et al.  Conditioned taste aversion induced by self-administered drugs: Paradox revisited , 1987, Neuroscience & Biobehavioral Reviews.

[56]  A. Riley,et al.  Conditioned Taste Aversions: A Behavioral Index of Toxicity , 1985, Annals of the New York Academy of Sciences.

[57]  A. Riley,et al.  The effect of morphine preexposure on the acquisition of morphine-induced taste aversions: A nonassociative effect , 1984 .

[58]  P. Best,et al.  Drug-preexposure effects in flavor-aversion learning: associative interference by conditioned environmental stimuli. , 1979, Journal of experimental psychology. Animal behavior processes.

[59]  V. Lolordo,et al.  Associative and nonassociative theories of the UCS preexposure phenomenon: implications for Pavlovian conditioning. , 1979, Psychological bulletin.

[60]  R. Baenninger,et al.  Habituation to illness: Effects of prior experience with the US on the formation of learned taste aversions in rats , 1977 .

[61]  T. Baker,et al.  Taste aversion disruption by drug pretreatment: Dissociative and drug-specific effects , 1977, Pharmacology Biochemistry and Behavior.

[62]  V. Lolordo,et al.  Drug exposure and the acquisition and retention of a conditioned taste aversion. , 1976, Journal of comparative and physiological psychology.

[63]  T. J. Wheeler,et al.  Drug pretreatment effects in drug induced taste aversions: Effects of dose and duration of pretreatment , 1976, Pharmacology Biochemistry and Behavior.

[64]  R. Wise,et al.  Both positive reinforcement and conditioned aversion from amphetamine and from apomorphine in rats. , 1976, Science.

[65]  R. Brackbill,et al.  Formation and retention of conditioned taste aversions and UCS habituation , 1976 .

[66]  A. Goudie,et al.  Effects of drug experience on drug induced conditioned taste aversions: Studies with amphetamine and fenfluramine , 1975, Psychopharmacologia.

[67]  H. Cappell,et al.  Conditioned aversion by amphetamine: Rates of acquisition and loss of the attenuating effects of prior exposure , 1975, Psychopharmacologia.

[68]  R. Elkins Conditioned flavor aversions to familiar tap water in rats: an adjustment with implications for aversion therapy treatment of alcoholism and obesity. , 1974, Journal of abnormal psychology.

[69]  D. Cannon,et al.  The effect of prior ethanol experience on ethanol-induced saccharin aversions. , 1974, Physiology & behavior.

[70]  P. Rozin,et al.  Specific hungers and poison avoidance as adaptive specializations of learning. , 1971, Psychological review.

[71]  William H. Meller,et al.  PSYCHOPHARMACOLOGY , 1957, Ministry with Persons with Mental Illness and Their Families, Second Edition.

[72]  Steve Reilly,et al.  Conditioned taste aversion : behavioral and neural processes , 2009 .

[73]  C. Kouimtsidis,et al.  Neurological and psychopathological sequelae associated with a lifetime intake of 40,000 ecstasy tablets. , 2006, Psychosomatics.

[74]  S. Schenk,et al.  Initial deficit and recovery of function after MDMA preexposure in rats , 2005, Psychopharmacology.

[75]  R. D. L. Garza,et al.  Relevance of rodent models of intravenous MDMA self-administration to human MDMA consumption patterns , 2005, Psychopharmacology.

[76]  C. Cunningham,et al.  Animal Models of Alcohol’s Motivational Effects , 2000, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

[77]  S. Revusky,et al.  Learned Associations Over Long Delays1 , 1970 .

[78]  F. Ervin,et al.  Appetites, aversions, and addictions: a model for visceral memory. , 1968, Recent advances in biological psychiatry.