The Development of a Novel in vitro Flow System to Evaluate Platelet Activation and Procoagulant Potential Induced by Bileaflet Mechanical Heart Valve Leakage Jets

[1]  A P Yoganathan,et al.  A microstructural flow analysis within a bileaflet mechanical heart valve hinge. , 1996, The Journal of heart valve disease.

[2]  S. Goto,et al.  Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions. , 1998, The Journal of clinical investigation.

[3]  A. Prasad,et al.  The entrainment behavior of a turbulent axisymmetric jet in a viscous host fluid , 2004 .

[4]  S H Chu,et al.  Turbulence characteristics downstream of bileaflet aortic valve prostheses. , 2000, Journal of biomechanical engineering.

[5]  Ajit P Yoganathan,et al.  Fluid mechanics of heart valves. , 2004, Annual review of biomedical engineering.

[6]  R T Schoephoerster,et al.  Effects of local geometry and fluid dynamics on regional platelet deposition on artificial surfaces. , 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.

[7]  R. Bodnar,et al.  Regulation of von Willebrand Factor Binding to the Platelet Glycoprotein Ib-IX by a Membrane Skeleton-dependent Inside-out Signal* , 2001, The Journal of Biological Chemistry.

[8]  A P Yoganathan,et al.  Bileaflet, tilting disc and porcine aortic valve substitutes: in vitro hydrodynamic characteristics. , 1984, Journal of the American College of Cardiology.

[9]  Brian Savage,et al.  Initiation of Platelet Adhesion by Arrest onto Fibrinogen or Translocation on von Willebrand Factor , 1996, Cell.

[10]  Ajit Yoganathan,et al.  An in vitro assessment by means of laser Doppler velocimetry of the medtronic advantage bileaflet mechanical heart valve hinge flow. , 2003, The Journal of thoracic and cardiovascular surgery.

[11]  Hwa Liang Leo,et al.  Bileaflet Aortic Valve Prosthesis Pivot Geometry Influences Platelet Secretion and Anionic Phospholipid Exposure , 2001, Annals of Biomedical Engineering.

[12]  Z. Ruggeri.  Mechanisms Initiating Platelet Thrombus Formation , 1997, Thrombosis and Haemostasis.

[13]  Wei Yin,et al.  Flow induced platelet activation in mechanical heart valves - in vitro studies , 2002, Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology.

[14]  Ajit P Yoganathan,et al.  Microflow fields in the hinge region of the CarboMedics bileaflet mechanical heart valve design. , 2002, The Journal of thoracic and cardiovascular surgery.

[15]  Brandon R. Travis,et al.  An In Vitro Study of the Hinge and Near-Field Forward Flow Dynamics of the St. Jude Medical® Regent™ Bileaflet Mechanical Heart Valve , 2000, Annals of Biomedical Engineering.

[16]  S. Deutsch,et al.  Integrating particle image velocimetry and laser Doppler velocimetry measurements of the regurgitant flow field past mechanical heart valves. , 2001, Artificial organs.

[17]  A P Yoganathan,et al.  A new method for noninvasive quantification of valvular regurgitation based on conservation of momentum. In vitro validation. , 1989, Circulation.

[18]  A P Yoganathan,et al.  In vitro pulsatile flow hemodynamics of five mechanical aortic heart valve prostheses. , 1992, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[19]  Z. Ruggeri,et al.  Mechanisms of Shear-induced Platelet Adhesion and Aggregation , 1993, Thrombosis and Haemostasis.

[20]  Ephraim M Sparrow,et al.  Flow Development in the Hydrodynamic Entrance Region of Tubes and Ducts , 1964 .

[21]  D. Monroe,et al.  A Cell-based Model of Hemostasis , 2001, Thrombosis and Haemostasis.

[22]  J. O'brien,et al.  Shear-induced platelet aggregation , 1990, The Lancet.

[23]  P. Bray,et al.  Duration of exposure to high fluid shear stress is critical in shear-induced platelet activation-aggregation , 2003, Thrombosis and Haemostasis.

[24]  A P Yoganathan,et al.  Velocity measurements and flow patterns within the hinge region of a Medtronic Parallel bileaflet mechanical valve with clear housing. , 1996, The Journal of heart valve disease.

[25]  L. McIntire,et al.  Ristocetin-dependent, but not botrocetin-dependent, binding of von Willebrand factor to the platelet glycoprotein Ib-IX-V complex correlates with shear-dependent interactions. , 2001, Blood.

[26]  R. Levine,et al.  A new theoretical model for noninvasive quantification of mitral regurgitation. , 1990, Journal of biomechanics.

[27]  C. Bodian,et al.  Dynamics of GPIIb/IIIa-mediated platelet-platelet interactions in platelet adhesion/thrombus formation on collagen in vitro as revealed by videomicroscopy. , 2003, Blood.

[28]  Larry V. McIntire,et al.  Real-time analysis of shear-dependent thrombus formation and its blockade by inhibitors of von Willebrand factor binding to platelets. , 1993 .

[29]  Catherine M. Otto,et al.  Practice of Clinical Echocardiography , 2007 .

[30]  A P Yoganathan,et al.  Quantification of regurgitant flow through bileaflet heart valve prostheses: theoretical and in vitro studies. , 1993, Ultrasound in medicine & biology.

[31]  N. Maugeri,et al.  Circulating platelet/polymorphonuclear leukocyte mixed–cell aggregates in patients with mechanical heart valve replacement , 2000, American journal of hematology.

[32]  A P Yoganathan,et al.  The sensitivity of indicators of thrombosis initiation to a bileaflet prosthesis leakage stimulus. , 2001, The Journal of heart valve disease.

[33]  Tomohiro Mizuno,et al.  Distinct and concerted functions of von Willebrand factor and fibrinogen in mural thrombus growth under high shear flow. , 2002, Blood.

[34]  C. Ball,et al.  Effects of low temperature on shear-induced platelet aggregation and activation. , 2004, The Journal of trauma.

[35]  J. Francis.  Platelet dysfunction detected at high shear in patients with heart valve disease , 2000, Platelets.

[36]  H. Shankaran,et al.  Aspects of hydrodynamic shear regulating shear-induced platelet activation and self-association of von Willebrand factor in suspension. , 2003, Blood.

[37]  Ajit P Yoganathan,et al.  An analysis of turbulent shear stresses in leakage flow through a bileaflet mechanical prostheses. , 2002, Journal of biomechanical engineering.

[38]  D C Naftel,et al.  Long-term performance of heart valve prostheses. , 2000, Current problems in cardiology.

[39]  A. Wolberg,et al.  A systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet function. , 2004, The Journal of trauma.

[40]  J. D. Hellums,et al.  Shear stress-induced von Willebrand factor binding to platelet glycoprotein Ib initiates calcium influx associated with aggregation. , 1992 .

[41]  Ajit P. Yoganathan,et al.  Comparison of the Hinge Flow Fields of Two Bileaflet Mechanical Heart Valves under Aortic and Mitral Conditions , 2004, Annals of Biomedical Engineering.

[42]  S. Sutera,et al.  Platelet adhesion and aggregation in pulsatile shear flow: effects of red blood cells. , 1998, Thrombosis research.

[43]  Larry V McIntire,et al.  Platelet Aggregation and Activation under Complex Patterns of Shear Stress , 2002, Thrombosis and Haemostasis.

[44]  K Watanabe,et al.  The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress. , 1991, The Journal of clinical investigation.

[45]  J R O'Brien,et al.  An independent haemostatic mechanism: shear induced platelet aggregation. , 1990, Advances in experimental medicine and biology.

[46]  S. Jackson,et al.  Intercellular calcium communication regulates platelet aggregation and thrombus growth , 2003, The Journal of cell biology.

[47]  G Rosenberg,et al.  Relative blood damage in the three phases of a prosthetic heart valve flow cycle. , 1993, ASAIO journal.

[48]  S. Diamond,et al.  Adhesion of normal erythrocytes at depressed venous shear rates to activated neutrophils, activated platelets, and fibrin polymerized from plasma. , 2002, Blood.

[49]  Ajit P. Yoganathan,et al.  An automated method for analysis and visualization of laser doppler velocimetry data , 1997, Annals of Biomedical Engineering.

[50]  R. Dewall,et al.  Evolution of mechanical heart valves. , 2000, The Annals of thoracic surgery.

[51]  C. Hufnagel,et al.  Cardiac valve replacement-its current status. , 1966, The Medical annals of the District of Columbia.

[52]  Mario Mazzucato,et al.  Sequential cytoplasmic calcium signals in a 2-stage platelet activation process induced by the glycoprotein Ibalpha mechanoreceptor. , 2002, Blood.

[53]  A. Yoganathan,et al.  Fluid Dynamics of Prosthetic Valves , 2007 .

[54]  H Reul,et al.  Leakage flow at mechanical heart valve prostheses: improved washout or increased blood damage? , 1999, The Journal of heart valve disease.

[55]  A. Guyton,et al.  Textbook of Medical Physiology , 1961 .

[56]  Y. Nemerson,et al.  Local Shear Conditions and Platelet Aggregates Regulate the Incorporation and Activity of Circulating Tissue Factor in ex-vivo Thrombi , 2002, Thrombosis and Haemostasis.

[57]  H Harasaki,et al.  Particle image velocimetry investigation of intravalvular flow fields of a bileaflet mechanical heart valve in a pulsatile flow. , 2000, The Journal of heart valve disease.

[58]  S. S. Kim,et al.  Long-term results with St. Jude Medical and CarboMedics prosthetic heart valves. , 2001, The Journal of heart valve disease.

[59]  N H Hwang,et al.  Computational fluid dynamics study of a protruded-hinge bileaflet mechanical heart valve. , 2001, The Journal of heart valve disease.

[60]  Morten Smerup,et al.  In-vivo turbulent stresses of bileaflet prosthesis leakage jets. , 2005, The Journal of heart valve disease.

[61]  P. Moerloose,et al.  Plasma Measurement of D-Dimer as Diagnostic Aid in Suspected Venous Thromboembolism: An Overview , 1994, Thrombosis and Haemostasis.