Thermal and circulatory response of tissue to localized pressure application: a mathematical model.

A mathematical model that predicts the thermal response of tissue during and after the application of localized pressure is described. The model predictions compare favorably with previously obtained experimental results. It is inferred that the principal cause of the transient temperature rise occurring after pressure application is a reactive hyperemic effect, while changes in metabolism are of little importance. The values of the tissue blood flow rates during reactive hyperemia are estimated.