Snoring and cardiovascular risk factors.

The association of snoring with some cardiovascular risk factors was studied cross-sectionally by a postal survey among 3750 males aged 40-59 years. In univariate analyses, snoring associated statistically significantly (P < 0.01) with hypertension, smoking, obesity, heavy alcohol use, physical inactivity, dyspnoea, hostility and morning tiredness. In a multiple logistic regression model adjusted by age, snoring associated significantly with smoking, obesity, physical inactivity, hostility and morning tiredness. When smoking was excluded from the multivariate model, alcohol use was also associated significantly with snoring. The association of snoring with smoking, and with obesity seemed to be almost independent from other studied correlates of snoring. Our results indicate that in further studies on predictive value of snoring with regard to coronary heart disease and stroke, the associations of snoring with hypertension, smoking, obesity, heavy alcohol use, physical inactivity and hostility have to be considered, as these risk characteristics may cause confounding effects.

[1]  C. Sullivan,et al.  Alcohol, snoring and sleep apnea. , 1982, Journal of neurology, neurosurgery, and psychiatry.

[2]  E. Bruce,et al.  Action of nicotine on the respiratory activity of the diaphragm and genioglossus muscles and the nerves that innervate them. , 1984, Respiration physiology.

[3]  J. Kaprio,et al.  Periodic breathing and hypoxia in snorers and controls: validation of snoring history and association with blood pressure and obesity , 1987, Acta neurologica Scandinavica.

[4]  V. Hoffstein,et al.  DETERMINANTS OF BLOOD PRESSURE IN SNORERS , 1988, The Lancet.

[5]  E. Murphy,et al.  Waking and ventilatory responses to laryngeal stimulation in sleeping dogs. , 1978, Journal of applied physiology: respiratory, environmental and exercise physiology.

[6]  L J Findley,et al.  Cognitive impairment in patients with obstructive sleep apnea and associated hypoxemia. , 1986, Chest.

[7]  F. Cirignotta,et al.  Some epidemiological data on snoring and cardiocirculatory disturbances. , 1980, Sleep.

[8]  J. Stradling,et al.  Relation between systemic hypertension and sleep hypoxaemia or snoring: analysis in 748 men drawn from general practice. , 1990, BMJ.

[9]  J. Kaprio,et al.  Snoring as a risk factor for ischaemic heart disease and stroke in men. , 1987, British medical journal.

[10]  H. Blackburn,et al.  Cardiovascular survey methods. , 1969, Monograph series. World Health Organization.

[11]  P Lavie,et al.  Prevalence of sleep apnea syndrome among patients with essential hypertension. , 1984, American heart journal.

[12]  L. Ferini-Strambi,et al.  Muscle fibre type and habitual snoring , 1991, The Lancet.

[13]  D. Deptula,et al.  Neuropsychological dysfunction in sleep apnea. , 1987, Sleep.

[14]  E. Bixler,et al.  SLEEP APNOEA IN A HYPERTENSIVE POPULATION , 1984, The Lancet.

[15]  F. Cirignotta,et al.  Clinical significance of snoring , 1984 .

[16]  A. Kales,et al.  Severe obstructive sleep apnea--II: Associated psychopathology and psychosocial consequences. , 1985, Journal of chronic diseases.

[17]  M Partinen,et al.  Obstructive sleep apnea and cephalometric roentgenograms. The role of anatomic upper airway abnormalities in the definition of abnormal breathing during sleep. , 1988, Chest.

[18]  P. Jennum,et al.  Snoring, sleep apnoea and cardiovascular risk factors: the MONICA II Study. , 1993, International journal of epidemiology.

[19]  J. Kaprio,et al.  The Finnish twin registry: baseline characteristics. Section I.: Materials, methods, representativeness and results for variables special to twin studies , 1979 .

[20]  G. Liistro,et al.  Pharyngeal shape and dimensions in healthy subjects, snorers, and patients with obstructive sleep apnoea. , 1990, Thorax.

[21]  D. Ingbar,et al.  Pathophysiology and treatment of sleep apnea. , 1985, Annual review of medicine.

[22]  M. Kaste,et al.  Snoring, sleep apnea syndrome, and stroke , 1992, Neurology.

[23]  F. Cirignotta,et al.  Pathogenic aspects of snoring and obstructive apnea syndrome. , 1988, Schweizerische medizinische Wochenschrift.

[24]  E V Dunn,et al.  Snoring as a risk factor for disease: an epidemiological survey. , 1985, British medical journal.

[25]  H. Zwick,et al.  Systemic hypertension in snorers with and without sleep apnea. , 1992, Chest.

[26]  R. Bhopal,et al.  IS SNORING A CAUSE OF VASCULAR DISEASE? An Epidemiological Review , 1989, The Lancet.

[27]  N. Zamel,et al.  Pharyngeal size in snorers, nonsnorers, and patients with obstructive sleep apnea. , 1986, The New England journal of medicine.

[28]  J. Kaprio,et al.  Hostility as a risk factor for mortality and ischemic heart disease in men. , 1988, Psychosomatic medicine.

[29]  H. Hein,et al.  Cardiovascular risk factors in snorers. A cross-sectional study of 3,323 men aged 54 to 74 years: the Copenhagen Male Study. , 1992, Chest.

[30]  B. Robinson,et al.  Sleep apnoea in alcoholic patients after withdrawal. , 1985, Clinical science.

[31]  W. Dement,et al.  Relative validity of self-reported snoring as a symptom of sleep apnea in a sleep clinic population. , 1991, Chest.

[32]  D. Hillman,et al.  Association of sleep apnoea with myocardial infarction in men , 1990, The Lancet.

[33]  W. Dement,et al.  Self-reported excessive daytime somnolence and impaired respiration in sleep. , 1986, Chest.

[34]  C. Sullivan,et al.  Upper airway closing pressures in snorers. , 1984, Journal of applied physiology: respiratory, environmental and exercise physiology.

[35]  J. Stradling,et al.  Predictors and prevalence of obstructive sleep apnoea and snoring in 1001 middle aged men. , 1991, Thorax.

[36]  S. Quan,et al.  Risk factors in a general population for snoring. Importance of cigarette smoking and obesity. , 1988, Chest.

[37]  D. Bates,et al.  Snoring increases the risk of stroke and adversely affects prognosis. , 1992, The Quarterly journal of medicine.

[38]  A. Gorin,et al.  Undiagnosed sleep apnea in patients with essential hypertension. , 1985, Annals of internal medicine.

[39]  M. Partinen,et al.  Sudden death and sleeping history among Finnish men , 1991, Journal of internal medicine.

[40]  J. E. Hovens,et al.  Snoring and anxiety dreams. , 1993, Sleep.

[41]  J. Kaprio,et al.  SNORING AS A RISK FACTOR FOR HYPERTENSION AND ANGINA PECTORIS , 1985, The Lancet.