Complete absence of external genitalia in limb-body wall complex: two cases.

Two neonates with limb-body wall complex (LBWC) and complete absence of the external genitalia are presented. Our patients are the sixth and seventh cases of complete absence of the external genitalia recorded in English publications and the first two cases associated with LBWC. The incidence of complete absence of the external genitalia in our newborn population during a period of 12 years (1975 to 1986) was one case per 13 420 births.

[1]  D. Nyberg,et al.  Limb-body wall complex: in utero sonographic diagnosis of a complicated fetal malformation. , 1986, AJR. American journal of roentgenology.

[2]  D. Weaver,et al.  The VATER Association: Analysis of 46 Patients , 1986 .

[3]  Y. Sivan,et al.  Anthropometric measurements of the newborn infant (27 to 41 gestational weeks). , 1984, Birth defects original article series.

[4]  M. Miller.  Structural defects as a consequence of early intrauterine constraint: limb deficiency, polydactyly, and body wall defects. , 1983, Seminars in Perinatology.

[5]  A. Atkinson,et al.  The pharmacological basis of therapeutics. 6th ed: By Alfred Goodman Gilman, Louis S. Goodman, and Alfred Gilman. 1843 pp., $45.00. Macmillan Publishing Co., Inc., New York, New York, 1980 , 1981 .

[6]  Van Allen Mi.  Fetal vascular disruptions: mechanisms and some resulting birth defects. , 1981, Pediatric annals.

[7]  M. V. Van Allen.  Fetal vascular disruptions: mechanisms and some resulting birth defects. , 1981, Pediatric annals.

[8]  C. Morton,et al.  Spondylocostal dysostosis associated with anal and urogenital anomalies in a Mennonite sibship. , 1981, American journal of medical genetics.

[9]  D. Sinniah,et al.  A syndrome of multiple congenital malformations with absent external genitalia, urethral and anal openings in one of twins. , 1980, Singapore medical journal.

[10]  R. Pagon,et al.  Body wall defects with reduction limb anomalies: a report of fifteen cases. , 1979, Birth defects original article series.

[11]  L. Papile,et al.  Persistent cloaca with absent penis and anal atresia in one of identical twins. , 1978, The Journal of pediatrics.

[12]  W. Smith,et al.  The Vater association. , 1974, American journal of diseases of children.

[13]  D W Smith,et al.  Recognizable patterns of human malformation. , 1976, Major problems in clinical pediatrics.

[14]  David W. Smith,et al.  The VATER association , 1973 .

[15]  N. Fitch,et al.  Persistent cloaca with no urethral, genital, or anal openings. , 1973, Teratology.

[16]  J. Kirshbaum.  Congenital absence of the external genitals , 1950 .

[17]  J. Kirshbaum.  Congenital absence of the external genitals; persistent primitive cloaca. , 1950, Jornal de Pediatria.

[18]  J. Gaddum.  THE PHARMACOLOGICAL BASIS OF THERAPEUTICS , 1941, Nature.