Vascular wall microenvironment: exosomes secreted by adventitial fibroblasts induced vascular calcification

[1]  Zhihong Liu,et al.  Progression of Vascular Calcification and Clinical Outcomes in Patients Receiving Maintenance Dialysis , 2023, JAMA network open.

[2]  Ling-Qing Yuan,et al.  Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study , 2023, Signal Transduction and Targeted Therapy.

[3]  S. Cha,et al.  Inhibition of mitochondrial phosphate carrier prevents high phosphate-induced superoxide generation and vascular calcification , 2023, Experimental & Molecular Medicine.

[4]  Guanwei Fan,et al.  GLSP and GLSP-derived triterpenes attenuate atherosclerosis and aortic calcification by stimulating ABCA1/G1-mediated macrophage cholesterol efflux and inactivating RUNX2-mediated VSMC osteogenesis , 2023, Theranostics.

[5]  Xiao Lin,et al.  BMF-AS1/BMF Promotes Diabetic Vascular Calcification and Aging both In Vitro and In Vivo , 2023, Aging and disease.

[6]  T. Rai,et al.  Circulating Extracellular Vesicle-Propagated microRNA Signature as a Vascular Calcification Factor in Chronic Kidney Disease , 2023, Circulation research.

[7]  Qing Li,et al.  High-Phosphate-Stimulated Macrophage-Derived Exosomes Promote Vascular Calcification via let-7b-5p/TGFBR1 Axis in Chronic Kidney Disease , 2022, Cells.

[8]  Jiacan Su,et al.  Exosome-based bone-targeting drug delivery alleviates impaired osteoblastic bone formation and bone loss in inflammatory bowel diseases , 2022, Cell reports. Medicine.

[9]  K. Hu,et al.  Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer , 2022, Molecular Cancer.

[10]  Ling-Qing Yuan,et al.  Protective role of small extracellular vesicles derived from HUVECs treated with AGEs in diabetic vascular calcification , 2022, Journal of Nanobiotechnology.

[11]  Feng Wu,et al.  The crosstalk between endothelial cells and vascular smooth muscle cells aggravates high phosphorus-induced arterial calcification , 2022, Cell Death & Disease.

[12]  Feng Wu,et al.  Histone Lysine Methylation Modification and Its Role in Vascular Calcification , 2022, Frontiers in Endocrinology.

[13]  Feng Wu,et al.  Cellular Crosstalk in the Vascular Wall Microenvironment: The Role of Exosomes in Vascular Calcification , 2022, Frontiers in Cardiovascular Medicine.

[14]  Xin-jie Chen,et al.  Pro-angiognetic and pro-osteogenic effects of human umbilical cord mesenchymal stem cell-derived exosomal miR-21-5p in osteonecrosis of the femoral head , 2022, Cell death discovery.

[15]  Chun-Yuan Chen,et al.  Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox , 2022, Nature Communications.

[16]  K. Ross,et al.  Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer , 2022, Molecular Cancer.

[17]  Feng Wu,et al.  H19 Promotes Osteoblastic Transition by Acting as ceRNA of miR-140-5p in Vascular Smooth Muscle Cells , 2022, Frontiers in Cell and Developmental Biology.

[18]  J. D. Macklis,et al.  Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting , 2021, Cell reports.

[19]  J. Olefsky,et al.  Exosomes as mediators of intercellular crosstalk in metabolism. , 2021, Cell metabolism.

[20]  Z. Szilvássy,et al.  BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate , 2021, International journal of molecular sciences.

[21]  J. Millán,et al.  Chronic Kidney Disease-Induced Arterial Media Calcification in Rats Prevented by Tissue Non-Specific Alkaline Phosphatase Substrate Supplementation Rather Than Inhibition of the Enzyme , 2021, Pharmaceutics.

[22]  Cheng-Gong Wang,et al.  Circular RNA AFF4 modulates osteogenic differentiation in BM-MSCs by activating SMAD1/5 pathway through miR-135a-5p/FNDC5/Irisin axis , 2021, Cell Death & Disease.

[23]  J. States,et al.  miRNA Dysregulation is an Emerging Modulator of Genomic Instability. , 2021, Seminars in cancer biology.

[24]  Jie Chen,et al.  Vascular Adventitial Fibroblasts-Derived FGF10 Promotes Vascular Smooth Muscle Cells Proliferation and Migration in vitro and the Neointima Formation in vivo , 2021, Journal of inflammation research.

[25]  S. Dima,et al.  Exosomal microRNAs as Biomarkers and Therapeutic Targets for Hepatocellular Carcinoma , 2021, International journal of molecular sciences.

[26]  Yu-Ming Kang,et al.  Extracellular vesicle-mediated miR135a-5p transfer in hypertensive rat contributes to vascular smooth muscle cell proliferation via targeting FNDC5. , 2021, Vascular pharmacology.

[27]  Jiacan Su,et al.  Exosome-guided bone targeted delivery of Antagomir-188 as an anabolic therapy for bone loss , 2021, Bioactive materials.

[28]  M. Taheri,et al.  Exploring the role of non-coding RNAs in autophagy , 2021, Autophagy.

[29]  Yu-jing Cao,et al.  Astragaloside IV Improves Tibial Defect in Rats and Promotes Proliferation and Osteogenic Differentiation of hBMSCs through MiR-124-3p.1/STAT3 Axis. , 2021, Journal of natural products.

[30]  R. Pereira,et al.  Inhibition of miR-29-3p isoforms via tough decoy suppresses osteoblast function in homeostasis but promotes intermittent parathyroid hormone-induced bone anabolism. , 2020, Bone.

[31]  S. Cha,et al.  Oxidative Stress by Ca2+ Overload is Critical forPhosphate-Induced Vascular Calcification. , 2020, American journal of physiology. Heart and circulatory physiology.

[32]  M. Hartman,et al.  Development and validation of a serum microRNA biomarker panel for detecting gastric cancer in a high-risk population , 2020, Gut.

[33]  Hongli Jiang,et al.  Indoxyl sulfate promotes osteogenic differentiation of vascular smooth muscle cells by miR-155-5p-dependent downregulation of matrix Gla protein via ROS/NF-κB signaling. , 2020, Experimental cell research.

[34]  Ling-Qing Yuan,et al.  Plasma Exosomes Derived From Patients With End-Stage Renal Disease and Renal Transplant Recipients Have Different Effects on Vascular Calcification , 2020, Frontiers in Cell and Developmental Biology.

[35]  Xiao-Yan Liu,et al.  MicroRNA-122 aggravates angiotensin II-mediated apoptosis and autophagy imbalance in rat aortic adventitial fibroblasts via the modulation of SIRT6-elabela-ACE2 signaling , 2020, European Journal of Pharmacology.

[36]  Zenong Yuan,et al.  Circular RNA circ_0011269 sponges miR‐122 to regulate RUNX2 expression and promotes osteoporosis progression , 2020, Journal of cellular biochemistry.

[37]  H. Renz,et al.  Spotlight on microRNAs in allergy and asthma , 2020, Allergy.

[38]  P. D’Haese,et al.  Chronic Kidney Disease–Induced Vascular Calcification Impairs Bone Metabolism , 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[39]  M. Dinger,et al.  Exploring the Role of Non-Coding RNAs in the Pathophysiology of Systemic Lupus Erythematosus , 2020, Biomolecules.

[40]  In-kyu Lee,et al.  Vascular Calcification—New Insights into Its Mechanism , 2020, International journal of molecular sciences.

[41]  Ellen F. Carney,et al.  The impact of chronic kidney disease on global health , 2020, Nature Reviews Nephrology.

[42]  Feng Wu,et al.  Melatonin alleviates vascular calcification and ageing through exosomal miR‐204/miR‐211 cluster in a paracrine manner , 2020, Journal of pineal research.

[43]  Hai-Jian Sun,et al.  MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression , 2019, Journal of extracellular vesicles.

[44]  Ling-Qing Yuan,et al.  Adipose tissue-derived omentin-1 attenuates arterial calcification via AMPK/Akt signaling pathway , 2019, Aging.

[45]  Lili Zhang,et al.  Exosomes from nicotine-stimulated macrophages accelerate atherosclerosis through miR-21-3p/PTEN-mediated VSMC migration and proliferation , 2019, Theranostics.

[46]  Xiao Lin,et al.  Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cell calcification/aging. , 2019, Life sciences.

[47]  O. Distler,et al.  Regulation of Fibroblast Apoptosis and Proliferation by MicroRNA‐125b in Systemic Sclerosis , 2019, Arthritis & Rheumatology.

[48]  Hsiang-Yuan Yeh,et al.  MicroRNA‐125b in vascular diseases: An updated systematic review of pathogenetic implications and clinical applications , 2019, Journal of cellular and molecular medicine.

[49]  F. Schena,et al.  Physical Exercise Modulates miR-21-5p, miR-129-5p, miR-378-5p, and miR-188-5p Expression in Progenitor Cells Promoting Osteogenesis , 2019, Cells.

[50]  Divya Singh,et al.  miR-487b-3p impairs osteoblastogenesis by targeting Notch-regulated ankyrin-repeat protein (Nrarp). , 2019, The Journal of endocrinology.

[51]  Ling-Qing Yuan,et al.  Aberration methylation of miR-34b was involved in regulating vascular calcification by targeting Notch1 , 2019, Aging.

[52]  Ling-Qing Yuan,et al.  Exosomes increased angiogenesis in papillary thyroid cancer microenvironment. , 2019, Endocrine-related cancer.

[53]  D. Mikhailidis,et al.  Arterial Stiffness in the Heart Disease of CKD. , 2019, Journal of the American Society of Nephrology : JASN.

[54]  S. Carugo,et al.  The Key Role of Phosphate on Vascular Calcification , 2019, Toxins.

[55]  Ling-Qing Yuan,et al.  Arterial Calcification Is Regulated Via an miR-204/DNMT3a Regulatory Circuit Both In Vitro and in Female Mice , 2018, Endocrinology.

[56]  M. Budoff,et al.  Risk factors for progression of coronary artery calcification in patients with chronic kidney disease: The CRIC study. , 2018, Atherosclerosis.

[57]  A. Durham,et al.  Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness , 2018, Cardiovascular research.

[58]  Graça Raposo,et al.  Shedding light on the cell biology of extracellular vesicles , 2018, Nature Reviews Molecular Cell Biology.

[59]  P. Ježek,et al.  Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis , 2017, Circulation.

[60]  Wei Chen,et al.  Hypoxic exosomes facilitate bladder tumor growth and development through transferring long non-coding RNA-UCA1 , 2017, Molecular Cancer.

[61]  S. Negi,et al.  Calcium Overload Accelerates Phosphate-Induced Vascular Calcification Via Pit-1, but not the Calcium-Sensing Receptor , 2017, Journal of atherosclerosis and thrombosis.

[62]  M. Vervloet,et al.  Vascular calcification in chronic kidney disease: different bricks in the wall? , 2017, Kidney international.

[63]  F. Jiang,et al.  Macrophage-stimulated microRNA expression in mural cells promotes transplantation-induced neointima formation , 2017, Oncotarget.

[64]  Xiaojie Yu,et al.  Exosomes as miRNA Carriers: Formation–Function–Future , 2016, International journal of molecular sciences.

[65]  J. Egido,et al.  Phosphate, pyrophosphate, and vascular calcification: a question of balance , 2015, European heart journal.

[66]  Bo Zhang,et al.  miR-29a-3p Attenuates Hypoxic Pulmonary Hypertension by Inhibiting Pulmonary Adventitial Fibroblast Activation , 2015, HYPERTENSION.

[67]  H. Gerhardt,et al.  Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling , 2014, Development.

[68]  J. Hamming,et al.  The 14q32 MicroRNA-487b Targets the Antiapoptotic Insulin Receptor Substrate 1 in Hypertension-Induced Remodeling of the Aorta , 2013, Annals of surgery.

[69]  J. Lötvall,et al.  Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes , 2013, Journal of extracellular vesicles.

[70]  Yun Zhang,et al.  Antagonist of microRNA‐21 improves balloon injury‐induced rat iliac artery remodeling by regulating proliferation and apoptosis of adventitial fibroblasts and myofibroblasts , 2012, Journal of cellular biochemistry.

[71]  N. Chen,et al.  Vascular Calcification: Pathophysiology and Risk Factors , 2012, Current Hypertension Reports.

[72]  C. Shanahan,et al.  Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate , 2011, Circulation research.

[73]  Marie C. M. Lin,et al.  MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by co-regulating BMP signaling , 2011, RNA biology.

[74]  P. Altevogt,et al.  Body fluid derived exosomes as a novel template for clinical diagnostics , 2011, Journal of Translational Medicine.

[75]  W. Kong,et al.  Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivo. , 2011, Kidney international.

[76]  E. Neven,et al.  Vascular Calcification in Chronic Renal Failure: What Have We Learned From Animal Studies? , 2011, Circulation research.

[77]  H. Kung,et al.  miRNA-Mediated Functional Changes through Co-Regulating Function Related Genes , 2010, PloS one.

[78]  W. Filipowicz,et al.  Regulation of mRNA translation and stability by microRNAs. , 2010, Annual review of biochemistry.

[79]  M. Kanbay,et al.  Phosphate – The Silent Stealthy Cardiorenal Culprit in All Stages of Chronic Kidney Disease , 2009, Blood Purification.

[80]  D. Bartel.  MicroRNAs: Target Recognition and Regulatory Functions , 2009, Cell.

[81]  K. Jirström,et al.  CRIM1 is localized to the podocyte filtration slit diaphragm of the adult human kidney , 2009, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[82]  T. Drüeke.  Arterial intima and media calcification: distinct entities with different pathogenesis or all the same? , 2008, Clinical journal of the American Society of Nephrology : CJASN.

[83]  Yin Tintut,et al.  Vascular calcification: pathobiology of a multifaceted disease. , 2008, Circulation.

[84]  W. Filipowicz,et al.  Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? , 2008, Nature Reviews Genetics.

[85]  N. Chen,et al.  Pathophysiology of Vascular Calcification in Chronic Kidney Disease , 2004, Circulation research.

[86]  G. Raposo,et al.  Exosomes: endosomal-derived vesicles shipping extracellular messages. , 2004, Current opinion in cell biology.

[87]  D. Bartel.  MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.

[88]  G. Kolle,et al.  CRIM1 Regulates the Rate of Processing and Delivery of Bone Morphogenetic Proteins to the Cell Surface* , 2003, Journal of Biological Chemistry.

[89]  A. Menrad,et al.  CRIM1 is involved in endothelial cell capillary formation in vitro and is expressed in blood vessels in vivo , 2002, Mechanisms of Development.

[90]  T. Lehtimäki,et al.  The prevalence of peripheral arterial disease and medial arterial calcification in patients with chronic renal failure: requirements for diagnostics. , 2002, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[91]  OUP accepted manuscript , 2021, Nucleic Acids Research.

[92]  OUP accepted manuscript , 2021, European Heart Journal.

[93]  O. Distler,et al.  MicroRNA-125b Regulates Fibroblast Apoptosis Proliferation in Systemic Sclerosis. , 2019, Arthritis & rheumatology.

[94]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..