Hemodynamic effects after conversion of arrhythmias.

Systemic and coronary hemodynamic parameters were determined during an arrhythmia and immediately after a direct current transthoracic shock given in an attempt to convert the arrhythmia to a sinus mechanism. No anesthesia or drugs were administered between the two studies. 16 patients with atrial fibrillation converted to sinus rhythm and five did not. In two patients with atrial flutter and one with supraventricular tachycardia, the arrhythmia was corrected. The arrhythmia persisted in a single patient with ventricular tachycardia. Utilizing each patient as his own control, we compared statistically various hemodynamic parameters before and after the shock. In addition, the group of patients whose atrial fibrillation terminated was compared to the group treated in the same manner but in which the atrial fibrillation persisted. Pressures in the right side of the heart decreased in both groups so that the changes appeared to be caused by factors associated with the transthoracic direct current shock or the catheterization procedure. The differences between those with atrial fibrillation who converted to sinus rhythm as compared to those who did not were a decrease in heart rate, an increase in stroke volume, and an increase in cardiac efficiency. There was no immediate effect on the cardiac output or coronary blood flow.

[1]  A. Selzer,et al.  Effects of atrial fibrillation upon the circulation in patients with mitral stenosis. , 1960, American heart journal.

[2]  M. I. Ferrer,et al.  SOME HEMODYNAMIC ASPECTS OF CARDIAC ARRHYTHMIAS IN MAN; A CLINICO-PHYSIOLOGIC CORRELATION. , 1964, American heart journal.

[3]  A. Kerkhof Minute volume determinations in mitral stenosis during auricular fibrillation and after restoration of normal rhythm , 1936 .

[4]  O. J. Broch,et al.  HÆMODYNAMIC STUDIES DURING AURICULAR FIBRILLATION AND AFTER RESTORATION OF SINUS RHYTHM , 1957, British heart journal.

[5]  R. Waters,et al.  A METHOD FOR THE DETERMINATION OF CYCLOPROPANE, ETHYLENE, AND NITROUS OXIDE IN BLOOD WITH THE VAN SLYKE-NEILL MANOMETRIC APPARATUS , 1937 .

[6]  H. Swan,et al.  Evaluation of a method for detection of mitral regurgitation from indicator-dilution curves recorded from the left atrium. , 1957, Proceedings of the staff meetings. Mayo Clinic.

[7]  R. C. Little Effect of atrial systole on ventricular pressure and closure of the A-V valves. , 1951, The American journal of physiology.

[8]  M. I. Ferrer,et al.  Some effects of quinidine sulfate on the heart and circulation in man. , 1948, American heart journal.

[9]  G. Rowe,et al.  Induced tachycardia: its effect upon the coronary hemodynamics, myocardial metabolism and cardiac efficiency of the intact dog. , 1958, The Journal of clinical investigation.

[10]  E. Braunwald,et al.  Studies on Starling9s Law of the Heart , 1961 .

[11]  H. Mcintosh,et al.  EXPERIENCE WITH "CARDIOVERSION" OF ATRIAL FIBRILLATION AND FLUTTER. , 1964, The American journal of cardiology.

[12]  J. P. Gilmore,et al.  Influence of atrial contraction and relaxation on closure of mitral valve. Observations on effects of autonomic nerve activity. , 1962, Circulation research.

[13]  O. Storstein,et al.  The hemodynamic effect of restoring normal sinus rhythm in patients with auricular fibrillation. , 1955, Scandinavian journal of clinical and laboratory investigation.

[14]  H. W. Elliott,et al.  CARDIOVASCULAR ACTIONS OF NARCOTIC ANALGESICS. , 1965, American heart journal.

[15]  W. Goodson,et al.  Theoretical and Practical Requirements for the Valid Measurement by Indicator‐Dilution of Regurgitant Flow Across Incompetent Valves , 1959, Circulation research.

[16]  H. Levine,et al.  Energetics of the human heart. , 1962, The American journal of cardiology.

[17]  P B Halmos,et al.  Effect of atrial fibrillation on cardiac output. , 1965, British heart journal.

[18]  M. I. Ferrer,et al.  Cardiocirculatory Performance in Atrial Flutter , 1955, Circulation.

[19]  T Killip,et al.  Hemodynamic effects after reversion from atrial fibrillation to sinus rhythm by precordial shock. , 1966, The Journal of clinical investigation.

[20]  R. Schlant,et al.  MANAGEMENT OF PATIENTS WITH ATRIAL FIBRILLATION. , 1964, The American journal of medicine.

[21]  C. W. Frank,et al.  Effect of auricular fibrillation on cardiac output, coronary blood flow and mean arterial blood pressure. , 1950, The American journal of physiology.

[22]  J. Kinsman,et al.  Auricular fibrillation; hemodynamic studies before and after conversion with quinidine. , 1952, American heart journal.

[23]  T. Killip SYNCHRONIZED DC PRECORDIAL SHOCK FOR ARRHYTHMIAS. SAFE NEW TECHNIQUE TO ESTABLISH NORMAL RHYTHM MAY BE UTILIZED ON AN ELECTIVE OR AN EMERGENCY BASIS. , 1963, JAMA.

[24]  H. Burchell A CLINICAL APPRAISAL OF ATRIAL TRANSPORT FUNCTION. , 1964, Lancet.

[25]  G E BURCH,et al.  The George Fahr Lecture: Certain Mechanical Peculiarities of the Human Cardiac Pump in Normal and Diseased States , 1952, Circulation.

[26]  B. Lown Electrical reversion of cardiac arrhythmias. , 1967, British heart journal.

[27]  B. Lown,et al.  "Cardioversion" of atrial fibrillation. A report on the treatment of 65 episodes in 50 patients. , 1963, The New England journal of medicine.

[28]  R. Gilbert,et al.  Effect on Circulation of Conversion of Atrial Fibrillation to Sinus Rhythm , 1963, Circulation.

[29]  Å. Gidlund,et al.  The haemodynamic basis of the symptoms and signs in mitral valvular disease. , 1952, The Quarterly journal of medicine.

[30]  L N KATZ,et al.  Effects of heart rate on coronary flow and cardiac oxygen consumption. , 1956, The American journal of physiology.

[31]  H. Mcintosh,et al.  The Changes in Cardiac Output with Reversion of Atrial Fibrillation to Sinus Rhythm , 1965, Circulation.

[32]  J. Mitchell,et al.  HEMODYNAMIC CONSEQUENCES OF ATRIAL FIBRILLATION AT CONSTANT VENTRICULAR RATES. , 1964, The American journal of medicine.

[33]  E. Braunwald,et al.  SYMPOSIUM ON CARDIAC ARRHYTHMIAS. INTRODUCTION WITH COMMENTS ON THE HEMODYNAMIC SIGNIFICANCE OF ATRIAL SYSTOLE. , 1964, The American journal of medicine.

[34]  S. A. Levine,et al.  Auricular fibrillation without other evidence of heart disease; a cause of reversible heart failure. , 1949, The American journal of medicine.

[35]  J. Williams,et al.  Effect of the cardiac arrhythmias on the coronary circulation. , 1959, Annals of internal medicine.

[36]  H. Mcintosh,et al.  HEMODYNAMIC EFFECTS OF SUPRAVENTRICULAR ARRHYTHMIAS. , 1964, The American journal of medicine.

[37]  W. Figueroa,et al.  Effect on cardiac output of conversion from atrial fibrillation to normal sinus mechanism , 1966 .

[38]  B. Lown "CARDIOVERSION" OF ARRHYTHMIAS. I. , 1964, Modern concepts of cardiovascular disease.

[39]  H. Alt,et al.  THE CARDIAC OUTPUT IN HEART DISEASE: I. COMPLETE HEART BLOCK, AURICULAR FIBRILLATION BEFORE AND AFTER THE RESTORATION TO NORMAL RHYTHM, SUBACUTE RHEUMATIC FEVER AND CHRONIC RHEUMATIC VALVULAR DISEASE , 1930 .

[40]  C. W. Frank,et al.  The Effect of Atrial and Ventricular Tachycardia on Cardiac Output, Coronary Blood Flow and Mean Arterial Blood Pressure , 1958, Circulation research.

[41]  A. Castellanos,et al.  Arrhythmias Related to Cardioversion , 1964, Circulation.

[42]  Barouh V. Berkovits,et al.  Comparison of alternating current with direct current electroshock across the closed chest , 1962 .

[43]  R. A. Carleton,et al.  CIRCULATORY CONSEQUENCES OF CHANGES IN CARDIAC RHYTHM PRODUCED IN PATIENTS BY TRANSTHORACIC DIRECT-CURRENT SHOCK. , 1964, The Journal of clinical investigation.

[44]  P. Taggart,et al.  Conversion of atrial fibrillation to sinus rhythm by direct-current shock. , 1963, Lancet.

[45]  L. Wolff Clinical Aspects of Paroxysmal Rapid Heart Action , 1942 .

[46]  G. Rowe,et al.  Hemodynamic effects of quinidine: including studies of cardiac work and coronary blood flow. , 1957, The Journal of clinical investigation.