The Role of Inflammation after Surgery for Elders (RISE) study: Examination of [11C]PBR28 binding and exploration of its link to post-operative delirium

[1]  S. Southwick,et al.  PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies , 2020, Nature Communications.

[2]  T. Travison,et al.  The Role of Inflammation after Surgery for Elders (RISE) study: Study design, procedures, and cohort profile , 2019, Alzheimer's & dementia.

[3]  Yiyun Huang,et al.  Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study , 2019, bioRxiv.

[4]  H. Hampel,et al.  The neuroinflammatory biomarker YKL-40 for neurodegenerative diseases: advances in development , 2019, Expert review of proteomics.

[5]  N. Terrando,et al.  Neuroinflammation and Perioperative Neurocognitive Disorders , 2019, Anesthesia and analgesia.

[6]  Seyed A Safavynia,et al.  The Role of Neuroinflammation in Postoperative Cognitive Dysfunction: Moving From Hypothesis to Treatment , 2019, Front. Psychiatry.

[7]  H. Otu,et al.  Development of a Dynamic Multi-Protein Signature of Postoperative Delirium , 2019, The journals of gerontology. Series A, Biological sciences and medical sciences.

[8]  K. Blennow,et al.  CSF sTREM2 in delirium—relation to Alzheimer’s disease CSF biomarkers Aβ42, t-tau and p-tau , 2018, Journal of Neuroinflammation.

[9]  Azeem Alam,et al.  Surgery, neuroinflammation and cognitive impairment , 2018, EBioMedicine.

[10]  S. Paganoni,et al.  Integrated magnetic resonance imaging and [11C]‐PBR28 positron emission tomographic imaging in amyotrophic lateral sclerosis , 2018, Annals of neurology.

[11]  Shengmei Zhu,et al.  Inflammatory markers in postoperative delirium (POD) and cognitive dysfunction (POCD): A meta-analysis of observational studies , 2018, PloS one.

[12]  M. Maze,et al.  Impact on the brain of the inflammatory response to surgery. , 2018, Presse medicale.

[13]  M. Berk,et al.  Post-Operative Cognitive Dysfunction: An exploration of the inflammatory hypothesis and novel therapies , 2018, Neuroscience & Biobehavioral Reviews.

[14]  S. Codeluppi,et al.  Disrupted Neuroglial Metabolic Coupling after Peripheral Surgery , 2018, The Journal of Neuroscience.

[15]  J. Werner,et al.  Monocyte-Dependent Suppression of T-Cell Function in Postoperative Patients and Abdominal Sepsis , 2017, Shock.

[16]  K. Blennow,et al.  Cerebrospinal Fluid S100B and Alzheimer's Disease Biomarkers in Hip Fracture Patients with Delirium , 2017, Dementia and Geriatric Cognitive Disorders Extra.

[17]  T. Travison,et al.  Prediction of Long-term Cognitive Decline Following Postoperative Delirium in Older Adults , 2017, The journals of gerontology. Series A, Biological sciences and medical sciences.

[18]  T. Travison,et al.  Alzheimer's-related cortical atrophy is associated with postoperative delirium severity in persons without dementia , 2017, Neurobiology of Aging.

[19]  X. Zhang,et al.  Astrocyte-derived CCL2 participates in surgery-induced cognitive dysfunction and neuroinflammation via evoking microglia activation , 2017, Behavioural Brain Research.

[20]  Pontus Plavén-Sigray,et al.  Assessment of simplified ratio-based approaches for quantification of PET [11C]PBR28 data , 2017, EJNMMI Research.

[21]  Zongze Zhang,et al.  NeurimmiRs and Postoperative Delirium in Elderly Patients Undergoing Total Hip/Knee Replacement: A Pilot Study , 2017, Front. Aging Neurosci..

[22]  T. Travison,et al.  High C‐Reactive Protein Predicts Delirium Incidence, Duration, and Feature Severity After Major Noncardiac Surgery , 2017, Journal of the American Geriatrics Society.

[23]  P. Matthews,et al.  Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans , 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[24]  P. Morgan,et al.  Mitochondrial Disease and Anesthesia , 2017 .

[25]  M. Maze,et al.  The immune response of the human brain to abdominal surgery , 2017, Annals of neurology.

[26]  Denis Guilloteau,et al.  Translocator Protein-18 kDa (TSPO) Positron Emission Tomography (PET) Imaging and Its Clinical Impact in Neurodegenerative Diseases , 2017, International journal of molecular sciences.

[27]  Corinna Burger,et al.  Neuroinflammatory challenges compromise neuronal function in the aging brain: Postoperative cognitive delirium and Alzheimer’s disease , 2017, Behavioural Brain Research.

[28]  Md Maqusood Alam,et al.  Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging in Neurological Diseases , 2017, Nuclear Medicine and Molecular Imaging.

[29]  Z. Zuo,et al.  Critical role of P2X7 receptors in the neuroinflammation and cognitive dysfunction after surgery , 2017, Brain, Behavior, and Immunity.

[30]  H. Otu,et al.  Higher C-Reactive Protein Levels Predict Postoperative Delirium in Older Patients Undergoing Major Elective Surgery: A Longitudinal Nested Case-Control Study , 2017, Biological Psychiatry.

[31]  Nicole R. Zürcher,et al.  Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis , 2016, Neurology.

[32]  N. Terrando,et al.  Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction , 2016, Journal of Neuroinflammation.

[33]  S. T. Govindarajan,et al.  Neuroinflammatory component of gray matter pathology in multiple sclerosis , 2016, Annals of neurology.

[34]  M. Maze,et al.  Perioperative cerebrospinal fluid and plasma inflammatory markers after orthopedic surgery , 2016, Journal of Neuroinflammation.

[35]  David C. Alsop,et al.  The short-term and long-term relationship between delirium and cognitive trajectory in older surgical patients , 2016, Alzheimer's & Dementia.

[36]  T. Travison,et al.  Quantifying the Severity of a Delirium Episode Throughout Hospitalization: the Combined Importance of Intensity and Duration , 2016, Journal of General Internal Medicine.

[37]  Ciprian Catana,et al.  Different partial volume correction methods lead to different conclusions: An 18F-FDG-PET study of aging , 2016, NeuroImage.

[38]  G. Katona,et al.  Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke , 2016, Nature Communications.

[39]  C. Granziera,et al.  In Vivo Imaging of Human Neuroinflammation. , 2016, ACS chemical neuroscience.

[40]  T. Travison,et al.  The Successful Aging After Elective Surgery Study: Cohort Description and Data Quality Procedures , 2015, Journal of the American Geriatrics Society.

[41]  Ives Cavalcante Passos,et al.  Inflammatory markers in post-traumatic stress disorder: a systematic review, meta-analysis, and meta-regression. , 2015, The lancet. Psychiatry.

[42]  B. V. van Munster,et al.  Preoperative protein profiles in cerebrospinal fluid in elderly hip fracture patients at risk for delirium: A proteomics and validation study , 2015, BBA clinical.

[43]  T. Libermann,et al.  Cytokines and Postoperative Delirium in Older Patients Undergoing Major Elective Surgery. , 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

[44]  S. E. Rooij,et al.  Timing Is Critical in Determining the Association Between Delirium and S100 Calcium‐Binding Protein B , 2015, Journal of the American Geriatrics Society.

[45]  H. Owen,et al.  The perioperative immune response , 2015, Current opinion in critical care.

[46]  E. Marcantonio,et al.  Cytokines and postoperative delirium in older patients undergoing major elective surgery , 2015, Alzheimer's & Dementia.

[47]  E. Marcantonio,et al.  Neuropsychological Profiles of an Elderly Cohort Undergoing Elective Surgery and the Relationship Between Cognitive Performance and Delirium , 2015, Journal of the American Geriatrics Society.

[48]  S. Rivest,et al.  The dynamics of monocytes and microglia in Alzheimer’s disease , 2015, Alzheimer's Research & Therapy.

[49]  Jean-Dominique Gallezot,et al.  Comparison of standardized uptake values with volume of distribution for quantitation of [(11)C]PBR28 brain uptake. , 2015, Nuclear medicine and biology.

[50]  B. Rosen,et al.  Evidence for brain glial activation in chronic pain patients. , 2015, Brain : a journal of neurology.

[51]  E. Zee,et al.  Postoperative cognitive dysfunction and microglial activation in associated brain regions in old rats , 2015, Neurobiology of Learning and Memory.

[52]  M. Baxter,et al.  Long-term Effects of Single or Multiple Neonatal Sevoflurane Exposures on Rat Hippocampal Ultrastructure , 2015, Anesthesiology.

[53]  Halina Skawina,et al.  Surgical outcomes. , 2015, Nursing standard (Royal College of Nursing (Great Britain) : 1987).

[54]  Kevin T. Chen,et al.  An SPM8-Based Approach for Attenuation Correction Combining Segmentation and Nonrigid Template Formation: Application to Simultaneous PET/MR Brain Imaging , 2014, The Journal of Nuclear Medicine.

[55]  S. D. Middleton,et al.  Cerebrospinal fluid markers of neuroinflammation in delirium: A role for interleukin-1β in delirium after hip fracture , 2014, Journal of psychosomatic research.

[56]  Bruce R. Rosen,et al.  Cortical surface-based analysis reduces bias and variance in kinetic modeling of brain PET data , 2014, NeuroImage.

[57]  Douglas Tommet,et al.  The CAM-S: development and validation of a new scoring system for delirium severity in 2 cohorts. , 2014, Annals of internal medicine.

[58]  Seong-Woon Yu,et al.  Translocator Protein 18 kDa Negatively Regulates Inflammation in Microglia , 2014, Journal of Neuroimmune Pharmacology.

[59]  Z. Zuo,et al.  Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB , 2014, Neuroscience.

[60]  A. MacLullich,et al.  Delirium and cerebrospinal fluid S100B in hip fracture patients: a preliminary study. , 2013, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[61]  J. Maldonado.  Neuropathogenesis of delirium: review of current etiologic theories and common pathways. , 2013, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[62]  Kimberly J. Jenko,et al.  A Genetic Polymorphism for Translocator Protein 18 Kda Affects both in Vitro and in Vivo Radioligand Binding in Human Brain to this Putative Biomarker of Neuroinflammation , 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[63]  Peter Herscovitch,et al.  Propofol Decreases In Vivo Binding of 11C-PBR28 to Translocator Protein (18 kDa) in the Human Brain , 2013, The Journal of Nuclear Medicine.

[64]  M. Ji,et al.  Changes in plasma and cerebrospinal fluid biomarkers in aged patients with early postoperative cognitive dysfunction following total hip-replacement surgery , 2013, Journal of Anesthesia.

[65]  D. Alsop,et al.  Novel risk markers and long-term outcomes of delirium: the successful aging after elective surgery (SAGES) study design and methods. , 2012, Journal of the American Medical Directors Association.

[66]  K. Blennow,et al.  Changes in serum and cerebrospinal fluid cytokines in response to non-neurological surgery: an observational study , 2012, Journal of Neuroinflammation.

[67]  S. Maier,et al.  Intracisternal Interleukin-1 Receptor Antagonist Prevents Postoperative Cognitive Decline and Neuroinflammatory Response in Aged Rats , 2012, The Journal of Neuroscience.

[68]  Richard E. Carson,et al.  Endotoxin-induced systemic inflammation activates microglia: [11C]PBR28 positron emission tomography in nonhuman primates , 2012, NeuroImage.

[69]  Philippe Hantraye,et al.  Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging , 2012, The Journal of Neuroscience.

[70]  K. Blennow,et al.  Cerebrospinal fluid markers of brain injury, inflammation, and blood-brain barrier dysfunction in cardiac surgery. , 2012, The Annals of thoracic surgery.

[71]  E. Marcantonio.  Postoperative delirium: a 76-year-old woman with delirium following surgery. , 2012, JAMA.

[72]  A. Absalom,et al.  A review of postoperative cognitive dysfunction and neuroinflammation associated with cardiac surgery and anaesthesia , 2012, Anaesthesia.

[73]  Roger N Gunn,et al.  An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28 , 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[74]  M. Maze,et al.  Resolving postoperative neuroinflammation and cognitive decline , 2011, Annals of neurology.

[75]  M. Eckenhoff,et al.  Human Alzheimer and Inflammation Biomarkers after Anesthesia and Surgery , 2011, Anesthesiology.

[76]  Colm Cunningham,et al.  Systemic inflammation and delirium: important co-factors in the progression of dementia. , 2011, Biochemical Society transactions.

[77]  Richard B. Banati,et al.  Positron emission tomography imaging of neuroinflammation , 2007, Neurotherapeutics.

[78]  M. Maze,et al.  Role of interleukin‐1β in postoperative cognitive dysfunction , 2010, Annals of neurology.

[79]  S. Straus,et al.  Does this patient have delirium?: value of bedside instruments. , 2010, JAMA.

[80]  Bruce Fischl,et al.  Improved tractography alignment using combined volumetric and surface registration , 2010, NeuroImage.

[81]  E. Marcantonio,et al.  Development of a unidimensional composite measure of neuropsychological functioning in older cardiac surgery patients with good measurement precision , 2010, Journal of clinical and experimental neuropsychology.

[82]  P. Eikelenboom,et al.  Systemic infection and delirium: when cytokines and acetylcholine collide , 2010, The Lancet.

[83]  S. Gordon,et al.  Alternative activation of macrophages: an immunologic functional perspective. , 2009, Annual review of immunology.

[84]  S. Inouye,et al.  The Confusion Assessment Method: A Systematic Review of Current Usage , 2008, Journal of the American Geriatrics Society.

[85]  P. Mainguet,et al.  Executive committee , 1991, Acta Endoscopica.

[86]  Jeih-San Liow,et al.  Radiation Dosimetry and Biodistribution in Monkey and Man of 11C-PBR28: A PET Radioligand to Image Inflammation , 2007, Journal of Nuclear Medicine.

[87]  R. P. Maguire,et al.  Consensus Nomenclature for in vivo Imaging of Reversibly Binding Radioligands , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[88]  Robert B. Innis,et al.  PET imaging with [11C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat , 2007, Neuroscience Letters.

[89]  Florence E. Turrentine,et al.  Surgical risk factors, morbidity, and mortality in elderly patients. , 2006, Journal of the American College of Surgeons.

[90]  C. Ritchie,et al.  The incidence of delirium associated with orthopedic surgery: a meta-analytic review , 2006, International Psychogeriatrics.

[91]  D. Nutt,et al.  Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function. , 2006, Trends in pharmacological sciences.

[92]  Anders M. Dale,et al.  An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest , 2006, NeuroImage.

[93]  R. Berger,et al.  Upregulation of Prostaglandin E2 and Interleukins in the Central Nervous System and Peripheral Tissue during and after Surgery in Humans , 2006, Anesthesiology.

[94]  G. Muehllehner,et al.  Positron emission tomography , 2006, Physics in medicine and biology.

[95]  M. Imaizumi,et al.  PET imaging with [ 11 C ] PBR 28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat , 2006 .

[96]  W. Henderson,et al.  Surgical Outcomes for Patients Aged 80 and Older: Morbidity and Mortality from Major Noncardiac Surgery , 2005, Journal of the American Geriatrics Society.

[97]  S. Gordon.  Alternative activation of macrophages , 2003, Nature Reviews Immunology.

[98]  L. Goldman,et al.  A clinical prediction rule for delirium after elective noncardiac surgery. , 1994, JAMA.

[99]  L. Goldman,et al.  A Clinical Prediction Rule for Delirium After Elective Noncardiac Surgery , 1994 .

[100]  M. Albert,et al.  The Delirium Symptom Interview: An Interview for the Detection of Delirium Symptoms in Hospitalized Patients , 1992, Journal of geriatric psychiatry and neurology.

[101]  S K Inouye,et al.  Clarifying confusion: the confusion assessment method. A new method for detection of delirium. , 1990, Annals of internal medicine.

[102]  Larry F. Lacey,et al.  Long-term effects of on , 1987 .