PET-CT-based auto-contouring in non-small-cell lung cancer correlates with pathology and reduces interobserver variability in the delineation of the primary tumor and involved nodal volumes.

[1]  Liesbeth Boersma,et al.  Feasibility of pathology-correlated lung imaging for accurate target definition of lung tumors. , 2007, International journal of radiation oncology, biology, physics.

[2]  K. Nackaerts,et al.  Prospective comparative study of integrated positron emission tomography-computed tomography scan compared with remediastinoscopy in the assessment of residual mediastinal lymph node disease after induction chemotherapy for mediastinoscopy-proven stage IIIA-N2 Non-small-cell lung cancer: a Leuven Lu , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[3]  Philippe Lambin,et al.  The current status of FDG-PET in tumour volume definition in radiotherapy treatment planning. , 2006, Cancer treatment reviews.

[4]  Marcel van Herk,et al.  Reduction of observer variation using matched CT-PET for lung cancer delineation: a three-dimensional analysis. , 2006, International Journal of Radiation Oncology, Biology, Physics.

[5]  A. Riegel,et al.  Variability of gross tumor volume delineation in head-and-neck cancer using CT and PET/CT fusion. , 2005, International journal of radiation oncology, biology, physics.

[6]  S. Rafla,et al.  The contribution of integrated PET/CT to the evolving definition of treatment volumes in radiation treatment planning in lung cancer. , 2005, International journal of radiation oncology, biology, physics.

[7]  Marcel van Herk,et al.  Observer variation in target volume delineation of lung cancer related to radiation oncologist-computer interaction: a 'Big Brother' evaluation. , 2005, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[8]  Jean-François Daisne,et al.  Inter-observer variability in the delineation of pharyngo-laryngeal tumor, parotid glands and cervical spinal cord: comparison between CT-scan and MRI. , 2005, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[9]  R. T. Ten Haken,et al.  High-dose radiation improved local tumor control and overall survival in patients with inoperable/unresectable non-small-cell lung cancer: long-term results of a radiation dose escalation study. , 2005, International journal of radiation oncology, biology, physics.

[10]  L. Boersma,et al.  142 Feasibility of pathology-correlated lung imaging for accurate target definition of lung tumors , 2005 .

[11]  C. Rübe,et al.  Comparison of different methods for delineation of 18F-FDG PET-positive tissue for target volume definition in radiotherapy of patients with non-Small cell lung cancer. , 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[12]  Philippe Lambin,et al.  Selective mediastinal node irradiation based on FDG-PET scan data in patients with non-small-cell lung cancer: a prospective clinical study. , 2005, International journal of radiation oncology, biology, physics.

[13]  Cyrill Burger,et al.  Automated functional image-guided radiation treatment planning for rectal cancer. , 2005, International journal of radiation oncology, biology, physics.

[14]  Philippe Lambin,et al.  Effects of radiotherapy planning with a dedicated combined PET-CT-simulator of patients with non-small cell lung cancer on dose limiting normal tissues and radiation dose-escalation: a planning study. , 2005, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[15]  Sadek Nehmeh,et al.  Does registration of PET and planning CT images decrease interobserver and intraobserver variation in delineating tumor volumes for non-small-cell lung cancer? , 2005, International journal of radiation oncology, biology, physics.

[16]  T. Stijnen,et al.  Meta-analysis of positron emission tomographic and computed tomographic imaging in detecting mediastinal lymph node metastases in nonsmall cell lung cancer. , 2005, The Annals of thoracic surgery.

[17]  Jean-François Daisne,et al.  Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG PET and validation with surgical specimen. , 2004, Radiology.

[18]  S. Bujenovic The role of positron emission tomography in radiation treatment planning. , 2004, Seminars in nuclear medicine.

[19]  B. Loo,et al.  A method of target definition in PET-based radiotherapy planning , 2004 .

[20]  J. Thie Understanding the standardized uptake value, its methods, and implications for usage. , 2004, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[21]  Lei Dong,et al.  Evaluation of a contour-alignment technique for CT-guided prostate radiotherapy: an intra- and interobserver study. , 2004, International journal of radiation oncology, biology, physics.

[22]  Sasa Mutic,et al.  Impact of FDG-PET on radiation therapy volume delineation in non-small-cell lung cancer. , 2004, International journal of radiation oncology, biology, physics.

[23]  Søren M Bentzen,et al.  High-tech in radiation oncology: should there be a ceiling? , 2004, International journal of radiation oncology, biology, physics.

[24]  Anne Bol,et al.  Tri-dimensional automatic segmentation of PET volumes based on measured source-to-background ratios: influence of reconstruction algorithms. , 2003, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[25]  Cyrill Burger,et al.  Radiation treatment planning with an integrated positron emission and computer tomography (PET/CT): a feasibility study. , 2003, International journal of radiation oncology, biology, physics.

[26]  T. Araki,et al.  Concurrent two-dimensional radiotherapy and weekly docetaxel in the treatment of stage III non-small cell lung cancer: a good local response but no good survival due to radiation pneumonitis. , 2003, Lung cancer.

[27]  G. V. von Schulthess,et al.  Impact of whole-body 18F-FDG PET on staging and managing patients for radiation therapy. , 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[28]  R. Fisher,et al.  Measurement of lung tumor volumes using three-dimensional computer planning software. , 2002, International journal of radiation oncology, biology, physics.

[29]  Curtis B Caldwell,et al.  The impact of (18)FDG-PET on target and critical organs in CT-based treatment planning of patients with poorly defined non-small-cell lung carcinoma: a prospective study. , 2002, International journal of radiation oncology, biology, physics.

[30]  Bernard Dubray,et al.  Conformal radiotherapy for lung cancer: different delineation of the gross tumor volume (GTV) by radiologists and radiation oncologists. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[31]  Arjan Bel,et al.  Definition of gross tumor volume in lung cancer: inter-observer variability. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[32]  S. Novello,et al.  Is there a standard strategy in the management of locally advanced non-small cell lung cancer? , 2001, Lung cancer.

[33]  C B Caldwell,et al.  Observer variation in contouring gross tumor volume in patients with poorly defined non-small-cell lung tumors on CT: the impact of 18FDG-hybrid PET fusion. , 2001, International journal of radiation oncology, biology, physics.

[34]  S. Dische,et al.  Failure-specific prognostic factors after continuous hyperfractionated accelerated radiotherapy (CHART) or conventional radiotherapy in locally advanced non-small-cell lung cancer: A competing risks analysis , 2001, British Journal of Cancer.

[35]  B J Mijnheer,et al.  Variability in target volume delineation on CT scans of the breast. , 2001, International journal of radiation oncology, biology, physics.

[36]  J. Luketich,et al.  The role of positron emission tomography in evaluating mediastinal lymph node metastases in non-small-cell lung cancer. , 2001, Clinical lung cancer.

[37]  V Kalff,et al.  Clinical impact of (18)F fluorodeoxyglucose positron emission tomography in patients with non-small-cell lung cancer: a prospective study. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[38]  A. E. Saarnak,et al.  Inter-observer variation in delineation of bladder and rectum contours for brachytherapy of cervical cancer. , 2000, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[39]  Gerald J. Kutcher,et al.  The impact of 18F-fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET) lymph node staging on the radiation treatment volumes in patients with non-small cell lung cancer , 2000 .

[40]  W. Curran,et al.  Final Results of Phase III Trial in Regionally Advanced Unresectable Non-Small Cell Lung Cancer : Radiation Therapy Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group , 2000 .

[41]  S. Kudoh,et al.  Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer. , 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[42]  R K Ten Haken,et al.  Estimation of tumor control probability model parameters from 3-D dose distributions of non-small cell lung cancer patients. , 1999, Lung cancer.

[43]  K Okajima,et al.  Differences in target outline delineation from CT scans of brain tumours using different methods and different observers. , 1999, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[44]  L. Stitt,et al.  Variability of target volume delineation in cervical esophageal cancer. , 1998, International journal of radiation oncology, biology, physics.

[45]  S U Berlangieri,et al.  The contribution of 18F-fluoro-2-deoxy-glucose positron emission tomographic imaging to radiotherapy planning in lung cancer. , 1998, Lung cancer.

[46]  S M Larson,et al.  Segmentation of lung lesion volume by adaptive positron emission tomography image thresholding , 1997, Cancer.

[47]  M. Martel,et al.  Results of high-dose thoracic irradiation incorporating beam's eye view display in non-small cell lung cancer: a retrospective multivariate analysis. , 1993, International journal of radiation oncology, biology, physics.

[48]  J. Hanley,et al.  A method of comparing the areas under receiver operating characteristic curves derived from the same cases. , 1983, Radiology.