ClC-3 expression enhances etoposide resistance by increasing acidification of the late endocytic compartment
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C. Higgins | K. Weylandt | A. Sardini | B. Wiedenmann | D. Carmena | M. Nebrig | J. Amey | N. Jansen-Rosseck
[1] F. Zunino,et al. Effect of a Novel Vacuolar-H+-ATPase Inhibitor on Cell and Tumor Response to Camptothecins , 2006, Journal of Pharmacology and Experimental Therapeutics.
[2] M. Gottesman,et al. Targeting multidrug resistance in cancer , 2006, Nature Reviews Drug Discovery.
[3] I. Tannock,et al. Inhibition of endosomal sequestration of basic anticancer drugs: influence on cytotoxicity and tissue penetration , 2006, British Journal of Cancer.
[4] A. Verkman,et al. Impaired acidification in early endosomes of ClC-5 deficient proximal tubule. , 2005, Biochemical and biophysical research communications.
[5] U. Kornak,et al. Loss of the chloride channel ClC‐7 leads to lysosomal storage disease and neurodegeneration , 2005, The EMBO journal.
[6] A. Verkman,et al. ClC-3 Chloride Channels Facilitate Endosomal Acidification and Chloride Accumulation* , 2005, Journal of Biological Chemistry.
[7] F. Lozupone,et al. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. , 2004, Journal of the National Cancer Institute.
[8] P. Ruszniewski,et al. Chemotherapy for Gastro-Enteropancreatic Endocrine Tumours , 2004, Neuroendocrinology.
[9] M. Gearing,et al. AP-3-dependent Mechanisms Control the Targeting of a Chloride Channel (ClC-3) in Neuronal and Non-neuronal Cells* , 2004, Journal of Biological Chemistry.
[10] H. Uramoto,et al. Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy. , 2003, Cancer treatment reviews.
[11] S. Simon,et al. Subcellular localization and activity of multidrug resistance proteins. , 2003, Molecular biology of the cell.
[12] J. Griffiths,et al. Increased tumour extracellular pH induced by Bafilomycin A1 inhibits tumour growth and mitosis in vivo and alters 5-fluorouracil pharmacokinetics. , 2003, European journal of cancer.
[13] A. Vandewalle,et al. Inhibitors of vacuolar H+-ATPase impair the preferential accumulation of daunomycin in lysosomes and reverse the resistance to anthracyclines in drug-resistant renal epithelial cells. , 2003, The Biochemical journal.
[14] S. Weinman,et al. The ClC-3 chloride channel promotes acidification of lysosomes in CHO-K1 and Huh-7 cells. , 2002, American journal of physiology. Cell physiology.
[15] M. Fjällskog,et al. Treatment with cisplatin and etoposide in patients with neuroendocrine tumors , 2001, Cancer.
[16] S. Raguz,et al. Human ClC-3 Is Not the Swelling-activated Chloride Channel Involved in Cell Volume Regulation* , 2001, The Journal of Biological Chemistry.
[17] A. Draguhn,et al. Disruption of ClC-3, a Chloride Channel Expressed on Synaptic Vesicles, Leads to a Loss of the Hippocampus , 2001, Neuron.
[18] Thomas J. Jentsch,et al. ClC-5 Cl--channel disruption impairs endocytosis in a mouse model for Dent's disease , 2000, Nature.
[19] S. Dzekunov,et al. Digestive vacuolar pH of intact intraerythrocytic P. falciparum either sensitive or resistant to chloroquine. , 2000, Molecular and biochemical parasitology.
[20] A. Hoeflich,et al. Insulin-like growth factor-I is an autocrine regulator of chromogranin A secretion and growth in human neuroendocrine tumor cells. , 2000, Cancer research.
[21] X. Liang,et al. A selective inhibitor of the osteoclastic V-H(+)-ATPase prevents bone loss in both thyroparathyroidectomized and ovariectomized rats. , 2000, The Journal of clinical investigation.
[22] R. Gillies,et al. pH and drug resistance. II. Turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs. , 1999, Biochemical pharmacology.
[23] A. L. A. L. E. Et,et al. (2Z,4E)‐5‐(5,6‐Dichloro‐2‐indolyl)‐2‐methoxy‐N‐ (1,2,2,6,6‐pentamethylpiperidin‐4‐yl)‐2,4‐pentadienamide, a Novel, Potent and Selective Inhibitor of the Osteoclast V‐ATPase. , 1999 .
[24] S. Simon,et al. Tamoxifen inhibits acidification in cells independent of the estrogen receptor. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[25] C. Parini,et al. (2Z,4E)-5-(5,6-dichloro-2-indolyl)-2-methoxy-N-(1,2,2,6,6- pentamethylpiperidin-4-yl)-2,4-pentadienamide, a novel, potent and selective inhibitor of the osteoclast V-ATPase. , 1998, Bioorganic & medicinal chemistry letters.
[26] T. Jentsch,et al. ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[27] S. Simon,et al. Defective Acidification in Human Breast Tumor Cells and Implications for Chemotherapy , 1998, The Journal of experimental medicine.
[28] M. Manfait,et al. Characterization of Acidic Vesicles in Multidrug-resistant and Sensitive Cancer Cells by Acridine Orange Staining and Confocal Microspectrofluorometry , 1997, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[29] B. Campling,et al. Mechanisms of resistance of human small cell lung cancer lines selected in VP‐16 and cisplatin , 1996, Cancer.
[30] S. Simon,et al. Defective pH regulation of acidic compartments in human breast cancer cells (MCF-7) is normalized in adriamycin-resistant cells (MCF-7adr). , 1996, Biochemistry.
[31] K. Funa,et al. Characterisation of a cell line (LCC-18) from a cultured human neuroendocrine-differentiated colonic carcinoma. , 1991, European journal of cancer.
[32] P. Okunieff,et al. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. , 1989, Cancer research.
[33] I. Pastan,et al. A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[34] C. Moertel. Karnofsky memorial lecture. An odyssey in the land of small tumors. , 1987, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[35] K. Yagawa,et al. Establishment of a carcinoembryonic antigen-producing cell line from human pancreatic carcinoma. , 1980, Gan.
[36] A. Leibovitz,et al. Classification of human colorectal adenocarcinoma cell lines. , 1976, Cancer research.
[37] G. Vitale,et al. IFN-β Is a Highly Potent Inhibitor of Gastroenteropancreatic Neuroendocrine Tumor Cell Growth In vitro , 2006 .
[38] T. Jentsch,et al. Physiological functions of CLC Cl- channels gleaned from human genetic disease and mouse models. , 2005, Annual review of physiology.
[39] R. Mayer,et al. Medical progress : Carcinoid tumors , 1999 .
[40] Susan Budavari,et al. The Merck index : an encyclopedia of chemicals, drugs, and biologicals , 1983 .
[41] A. Bornstein. Carcinoid tumors. , 1957, The Journal of the Kentucky State Medical Association.