Cellular and synaptic alterations in the aging brain

[1]  K. Fuxe,et al.  Aspects of neural plasticity in the central nervous system—IV. Chemical anatomical studies on the aging brain , 1990, Neurochemistry International.

[2]  K. Fuxe,et al.  Aspects of neural plasticity in the central nervous system—VII. Theoretical aspects of brain communication and computation , 1990, Neurochemistry International.

[3]  K. Fuxe,et al.  Neurotensin reduces the affinity of dopamine D2 receptors in membranes from post mortem human caudate-putamen , 1990, Neuroscience Letters.

[4]  C. Benedetti,et al.  Opioid Analgesia: Recent Advances in Systemic Administration , 1990 .

[5]  C. Franceschi,et al.  Cell proliferation, cell death and aging , 1989, Aging.

[6]  K. Fuxe,et al.  Some aspects of the communicational and computational organization of the brain. , 1989, Acta physiologica Scandinavica.

[7]  Y. Uchida,et al.  Neurotrophic action of Alzheimer's disease brain extract is due to the loss of inhibitory factors for survival and neurite formation of cerebral cortical neurons , 1989, Brain Research.

[8]  K. Fuxe,et al.  Morphometrical and microdensitometrical studies on phenylethanolamine-N-methyltransferase- and neuropeptide Y-immunoreactive neurons in the rostral medulla oblongata of the adult and old male rat , 1988, Neuroscience.

[9]  K. Fuxe,et al.  Polyamines, Ornithine Decarboxylase, and Diamine Oxidase in the Substantia Nigra and Striatum of the Male Rat After Hemitransection , 1988, Journal of neurochemistry.

[10]  W. Spirduso,et al.  Reaction time and nigrostriatal dopamine function: the effects of age and practice , 1988, Brain Research.

[11]  R. Faull,et al.  Neuroprotective effects of adenosine. , 1988, Trends in pharmacological sciences.

[12]  B. Sabel,et al.  Pharmacological Approaches to the Treatment of Brain and Spinal Cord Injury , 1988, Springer US.

[13]  B. Fredholm,et al.  How does adenosine inhibit transmitter release? , 1988, Trends in pharmacological sciences.

[14]  I. Creese,et al.  Age-related differential recovery rates of rat striatal D-1 dopamine receptors following irreversible inactivation. , 1988, European journal of pharmacology.

[15]  Hiroshi Watanabe,et al.  Differential decrease in the rate of dopamine synthesis in several dopaminergic neurons of aged rat brain , 1987, Experimental Gerontology.

[16]  S. Hyman,et al.  Mechanisms of trans-synaptic regulation of gene expression , 1987, Trends in Neurosciences.

[17]  Paul D. Coleman,et al.  Neuron numbers and dendritic extent in normal aging and Alzheimer's disease , 1987, Neurobiology of Aging.

[18]  D. Neary,et al.  Catecholaminergic neurones assessed ante-mortem in Alzheimer's disease , 1987, Brain Research.

[19]  G. Kreutzberg,et al.  Synaptic and extrasynaptic localization of adenosine binding sites in the rat hippocampus , 1987, Neuroscience.

[20]  K. Fuxe,et al.  Evidence for the existence of ornithine decarboxylase-immunoreactive neurons in the rat brain , 1987, Neuroscience Letters.

[21]  D. Neary,et al.  Somatostatin content and release measured in cerebral biopsies from demented patients , 1987, Journal of the Neurological Sciences.

[22]  C. Perego,et al.  Age-related changes in metabolic responses to chronic monoamine depletion in central dopaminergic and serotonergic systems of rats treated with reserpine , 1987, Neurobiology of Aging.

[23]  Pietro Calissano,et al.  Nerve growth factor as a paradigm for other polypeptide growth factors , 1986, Trends in Neurosciences.

[24]  D. Middlemiss,et al.  Binding of the Novel Serotonin Agonist 8‐Hydroxy‐2‐(Di‐n‐Propylamino) Tetralin in Normal and Alzheimer Brain , 1986, Journal of neurochemistry.

[25]  J. Olney,et al.  Glutamate and the pathophysiology of hypoxic–ischemic brain damage , 1986, Annals of neurology.

[26]  N. Carfagna,et al.  Brain catecholamine content and turnover in aging rats , 1985, Experimental Gerontology.

[27]  B. Winblad,et al.  Transmitter deficits in Alzheimer's disease , 1985, Neurochemistry International.

[28]  K. Fuxe,et al.  Effects of neurotoxic and mechanical lesions of the mesostriatal dopamine pathway on striatal polyamine levels in the rat: Modulation by chronic ganglioside GM1 treatment , 1985, Neuroscience Letters.

[29]  Behram N. Kursunoglu,et al.  Information Processing in Biological Systems , 1985, Studies in the Natural Sciences.

[30]  Luigi F. Agnati,et al.  Receptor‐receptor interactions in the central nervous system. A new integrative mechanism in synapses , 1985, Medicinal research reviews.

[31]  K. Fuxe,et al.  Effects of lesions and ganglioside GM1 treatment on striatal polyamine levels and nigral DA neurons. A role of putrescine in the neurotropic activity of gangliosides. , 1985, Acta physiologica Scandinavica.

[32]  P. Jenner.  Excitotoxins. (Wenner-Gren International Symposium Series; Vol 39.) , 1985 .

[33]  R. Sapolsky.  A mechanism for glucocorticoid toxicity in the hippocampus: increased neuronal vulnerability to metabolic insults , 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[34]  B. McEwen,et al.  Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging , 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[35]  M. Folstein,et al.  EFFECTS OF AGE ON DOPAMINE AND SEROTONIN RECEPTORS MEASURED BY POSITRON TOMOGRAPHY IN THE LIVING HUMAN BRAIN , 1984, Science.

[36]  C. Gerfen.  The neostriatal mosaic: compartmentalization of corticostriatal input and striatonigral output systems , 1984, Nature.

[37]  J. Waddington,et al.  Loss of rat striatal dopamine receptors with ageing is selective for D-2 but not D-1 sites: association with increased non-specific binding of the D-1 ligand [3H]piflutixol. , 1984, European journal of pharmacology.

[38]  G. Roth,et al.  Effect of aging on recovery of striatal dopamine receptors following N-ethoxycarbonyl-2-ethoxy-1, 2-dihydroquinoline (EEDQ) blockade. , 1984, Life sciences.

[39]  I. Creese,et al.  Dopamine receptor turnover rates in rat striatum are age-dependent. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[40]  K. Fuxe,et al.  Aging brain and dopamine receptors: abnormal regulation by CCK-8 of 3H-spiperone labeled dopamine receptors in striatal membranes. , 1984, Acta Physiologica Scandinavica.

[41]  S. Skaper,et al.  Low molecular weight agents support survival of cultured neurons from the central nervous system , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[42]  K. Fuxe,et al.  New concepts on the structure of the neuronal networks: The miniaturization and hierarchical organization of the central nervous system , 1984, Bioscience reports.

[43]  B. McEwen,et al.  The adrenocorticol stress-response in the aged male rat: Impairment of recovery from stress , 1983, Experimental Gerontology.

[44]  P C Jackson,et al.  Reduced activity during development delays the normal rearrangement of synapses in the rabbit ciliary ganglion. , 1983, The Journal of physiology.

[45]  G. Gilad,et al.  Polyamine biosynthesis is required for survival of sympathetic neurons after axonal injury , 1983, Brain Research.

[46]  S. Snyder,et al.  Adenosine receptors: autoradiographic evidence for their location on axon terminals of excitatory neurons. , 1983, Science.

[47]  W. Thompson.  Synapse elimination in neonatal rat muscle is sensitive to pattern of muscle use , 1983, Nature.

[48]  D. Neary,et al.  Amino acid release from biopsy samples of temporal neocortex from patients with Alzheimer's disease , 1983, Brain Research.

[49]  N. Sims,et al.  Biochemical Evidence of Selective Nerve Cell Changes in the Normal Ageing Human and Rat Brain , 1983, Journal of neurochemistry.

[50]  G. Vantini,et al.  Changes with age in rat central monoaminergic system responses to cold stress , 1982, Neurobiology of Aging.

[51]  K. Fuxe,et al.  New vistas on synaptic plasticity: the receptor mosaic hypothesis of the engram. , 1982, Medical biology.

[52]  J. Jolles,et al.  Neuropeptides derived from pro-opiocortin: behavioral, physiological, and neurochemical effects. , 1982, Physiological reviews.

[53]  E. Perry,et al.  Neuropeptides in Alzheimer's disease, depression and schizophrenia A post mortem analysis of vasoactive intestinal peptide and cholecystokinin in cerebral cortex , 1981, Journal of the Neurological Sciences.

[54]  J. Joseph,et al.  Development of dopamine receptor denervation supersensitivity in the neostriatum of the senescent rat. , 1981, Life sciences.

[55]  B. Sabel,et al.  Extensive loss of subcortical neurons in the aging rat brain , 1981, Experimental Neurology.

[56]  J. Joseph,et al.  Neostriatal dopamine receptor loss and behavioral deficits in the senescent rat. , 1981, Life sciences.

[57]  J. Joseph,et al.  Effect of age on sensitivity to pain and brain opiate receptors , 1981, Neurobiology of Aging.

[58]  L. Iversen,et al.  ARGININE VASOPRESSIN AND CHOLINE ACETYLTRANSFERASE IN BRAINS OF PATIENTS WITH ALZHEIMER TYPE SENILE DEMENTIA , 1980, The Lancet.

[59]  S. Pradhan.  Central neurotransmitters and aging. , 1980, Life sciences.

[60]  B. Campbell,et al.  Animal models of declining memory in the aged: short-term and spatial memory in the aged rat. , 1980, Journal of gerontology.

[61]  B. Ghetti,et al.  Effect of aging on neurotransmitter receptor binding in rat and human brain. , 1979, Life sciences.

[62]  G. Lynch,et al.  Hippocampal aging and adrenocorticoids: quantitative correlations. , 1978, Science.

[63]  H R Johnson,et al.  Aging in the rhesus monkey: debilitating effects on short-term memory. , 1978, Journal of gerontology.

[64]  J. Changeux,et al.  Consequences of blocking the nerve with a local anaesthetic on the evolution of multiinnervation at the regenerating neuromuscular junction of the rat , 1978, Brain Research.

[65]  M. Bonati,et al.  Dihydropteridine reductase and tyrosine hydroxylase activities in rat brain during development and senescence: a comparative study , 1977, Brain Research.

[66]  H. Selye,et al.  [Stress without distress]. , 1976, Bruxelles medical.

[67]  P. Rakić.  Local circuit neurons. , 1975, Neurosciences Research Program bulletin.

[68]  Arnold B. Scheibel,et al.  Structural Changes in the Aging Brain , 1975 .

[69]  E. Roberts.  [Model of the vertebrate nervous system based largely on disinhibition. Key role of the GABA system]. , 1973, Zhurnal evoliutsionnoi biokhimii i fiziologii.

[70]  R. D. Myers.  Neurohumoral Coding of Brain Function , 1973, Science.

[71]  William Bondari,et al.  Age Changes in the Neuronal Microenvironment , 1972, Science.

[72]  A. Routtenberg,et al.  Intrastriatal spread of catecholamines in senescent rats. , 1971, Journal of gerontology.

[73]  U. Ungerstedt,et al.  6-Hydroxy-dopamine induced degeneration of central monoamine neurons. , 1968, European journal of pharmacology.

[74]  C. L. Goodrick.  Learning, retention, and extinction of a complex maze habit for mature-young and senescent Wistar albino rats. , 1968, Journal of gerontology.

[75]  A. Oliverio,et al.  Effects of age on maze learning and avoidance conditioning of mice , 1966 .

[76]  C. Salzman.  Aging Brain and Dementia: New Trends in Diagnosis and Therapy , 1991 .

[77]  K. Fuxe,et al.  Regional differences in glucocorticoid receptor immunoreactivity among neuropeptide Y immunoreactive neurons of the rat brain. , 1989, Acta physiologica Scandinavica.

[78]  K. Fuxe,et al.  Regeneration in the central nervous system: concepts and facts. , 1988, Advances and technical standards in neurosurgery.

[79]  D. M. Feeney,et al.  Catecholamines and Recovery of Function after Brain Damage , 1988 .

[80]  C. Wischik,et al.  New trends in aging research , 1988 .

[81]  M. Trabucchi,et al.  The central dopaminergic system: susceptibility to risk factors for accelerated aging. , 1988, Gerontology.

[82]  K. Fuxe,et al.  Receptor-Receptor Interactions , 1987, Wenner-Gren Center International Symposium Series.

[83]  K. Fuxe,et al.  Receptor-receptor interactions : a new intramembrane integrative mechanism : proceedings of an international symposium held at the Wenner-Gren Center, Stockholm, October 9th-11th, 1986 , 1987 .

[84]  K. Fuxe,et al.  Aspects on the Integrative Capabilities of the Central Nervous System: Evidence for ‘Volume Transmission’ and its Possible Relevance for Receptor-Receptor Interactions , 1987 .

[85]  K. Fuxe,et al.  Morphofunctional studies on the neuropeptide Y/adrenaline costoring terminal systems in the dorsal cardiovascular region of the medulla oblongata. Focus on receptor-receptor interactions in cotransmission. , 1986, Progress in brain research.

[86]  K. Fuxe,et al.  Aspects on the information handling by the central nervous system: focus on cotransmission in the aged rat brain. , 1986, Progress in brain research.

[87]  C. Mountjoy.  Correlations between neuropathological and neurochemical changes. , 1986, British medical bulletin.

[88]  D. Bowen,et al.  Biochemical studies of nerve cells and energy metabolism in Alzheimer's disease. , 1986, British medical bulletin.

[89]  D. K. Berg.  New neuronal growth factors. , 1984, Annual review of neuroscience.

[90]  K. Fuxe,et al.  Computer-assisted morphometry and microdensitometry of transmitter-identified neurons with special reference to the mesostriatal dopamine pathway. III: Studies on aging processes , 1984 .

[91]  F Benfenati,et al.  Computer-assisted morphometry and microdensitometry of transmitter- identified neurons with special reference to the mesostriatal dopamine pathway. Methodological aspects. , 1984, Acta physiologica Scandinavica. Supplementum.

[92]  K. Fuxe,et al.  Studies on aging processes. , 1984, Acta physiologica Scandinavica. Supplementum.

[93]  K. Fuxe,et al.  Receptor—receptor interactions: possible new mechanisms for the action of some antidepressant drugs , 1983 .

[94]  V. Frolkis,et al.  Aging of the Brain , 1982 .

[95]  M. Kafka.  Central nervous system control of mammalian circadian rhythms , 1983 .

[96]  A. Agnoli.  Aging brain and ergot alkaloids , 1983 .

[97]  M Conrad,et al.  Microscopic-macroscopic interface in biological information processing. , 1983, Bio Systems.

[98]  A. Friedhoff,et al.  Frontiers in Neuropsychiatric Research , 1983, Palgrave Macmillan UK.

[99]  J. Cervós-Navarro,et al.  Brain aging : neuropathology and neuropharmacology , 1983 .

[100]  M. Peng,et al.  No neuron loss from hypothalamic nuclei of old male rats. , 1982, Gerontology.

[101]  E. Giacobini.  The Aging brain : cellular and molecular mechanisms of aging in the nervous system , 1982 .

[102]  R. Adler,et al.  Trophic and Specifying Factors Directed to Neuronal Cells , 1981 .

[103]  R. Sprott.  Age, learning ability, and intelligence , 1980 .

[104]  Denise C. Park,et al.  Handbook of the Psychology of Aging , 1979 .

[105]  M. Peng,et al.  Regional differences of neuron loss of rat brain in old age. , 1979, Gerontology.

[106]  J. Ordy,et al.  Clinical, morphologic, and neurochemical aspects in the aging central nervous system , 1975 .

[107]  W. Bondareff,et al.  Age changes in the neuronal microenvironment. , 1972, Science.