A Review on different formulations of Punica granatum

Plant-based preparations have been used since olden times and playing a role as a curative against different human and animal diseases. The curiosity in conventional medicines has increased in different parts of the world. A well known olden fruit named Punica granatum is commonly known as Pomegranate, Anar or Dalim in North India whose curative qualities have rebounded and echoed throughout the millennia. It contains numerous valuable ingredients such as flavonoids, ellagitannin, punicalagin, ellagic acid, vitamins and minerals. The main constituents including punicalagins and ellagitannin are responsible for beyond measure health benefits due to its strong antioxidant activity. As well, constituents of pomegranate show health-promoting effects through the modulation of physiological and biochemical pathways. Recent evidence suggested that pomegranates fruits, peels and seeds demonstrate therapeutics implications in health management via inhibition of free radical effect and modulation of enzymes activity linked with disease development. In this review, we summarize the work of different researchers on pomegranate in the different formulations for the different diseases.

[1]  S. A. Muhsin,et al.  In vivo antimicrobial inhibition of Punica Granatum extracts as mouthwash , 2017 .

[2]  E. Selvarajan,et al.  Fermentative preparation of functional drink from Punica granatum using lactic acid bacteria and exploring its anti-tumor potential , 2017 .

[3]  Jomjai Peerapattana,et al.  Antibacterial Inhibitory Effects of Punica Granatum Gel on Cariogenic Bacteria: An in vitro Study , 2017, International journal of clinical pediatric dentistry.

[4]  H. Niknahad,et al.  Assessing the effect of pomegranate fruit seed extract mouthwash on dental plaque and gingival inflammation , 2016 .

[5]  A. Aslani,et al.  Design, Formulation and Evaluation of an Oral Gel from Punica Granatum Flower Extract for the Treatment of Recurrent Aphthous Stomatitis. , 2016, Advanced pharmaceutical bulletin.

[6]  L. Cavalheiro,et al.  EXTRACT OF Punica granatum L.: AN ALTERNATIVE TO BHT AS AN ANTIOXIDANT IN SEMISSOLID EMULSIFIED SYSTEMS , 2016 .

[7]  C. R. Pereira,et al.  Punica granatum L. Hydrogel for Wound Care Treatment: From Case Study to Phytomedicine Standardization , 2016, Molecules.

[8]  A. Dahlan,et al.  FORMULATION, CHARACTERIZATION AND DETERMINATION OF ANTIBACTERIAL ACTIVITY OF POMEGRANATE (Punica granatum) GEL. , 2015 .

[9]  W. Tiyaboonchai,et al.  Mucoadhesive polyethylenimine–dextran sulfate nanoparticles containing Punica granatum peel extract as a novel sustained-release antimicrobial , 2015, Pharmaceutical development and technology.

[10]  T. Mahmood,et al.  Topical microemulsion containing Punica granatum extract: its control over skin erythema and melanin in healthy Asian subjects , 2014, Postepy dermatologii i alergologii.

[11]  F. Costa,et al.  Therapeutic potential of biodegradable microparticles containing Punica granatum L. (pomegranate) in murine model of asthma , 2013, Inflammation Research.

[12]  Shripad Bairagi,et al.  In Vivo Topical Wound Healing Activity of Punica Granatum Peel Extract on Rats , 2013 .

[13]  Harmanpreet Singh,et al.  FORMULATION AND EVALUATION OF NIOSOMES CONTAINING PUNICALAGIN FROM PEELS OF PUNICA GRANATUM , 2012 .

[14]  M. C. Eswaraiah,et al.  Formulation and Evaluation of a Herbal Lipstick from Punica granatum Fruit Peel , 2012 .

[15]  V. Kadam,et al.  Antibacterial potential of herbal formulation. , 2009 .

[16]  Md.,et al.  Formulation of Value Added Beef Meatballs with Pomegranate ( Punica granatum) Extract as a Source of Natural Antioxidant , 2018 .

[17]  T. Satyanarayana,et al.  FORMULATION AND EVALUATION OF HERBAL VANISHING CREAM CONTAINING PUNICA GRANATUM , 2016 .

[18]  K. WijetungeW.M.A.N. PREPARATION OF MEDICINAL SOAP PRODUCTS USING THE LEAF EXTRACTS OF PUNICA GRANATUM ( POMEGRANATE ) , 2016 .

[19]  Sneha S. Patil,et al.  DETERMINATION OF ACTIVE PHYTOCOMPOUNDS FROM FORMULATED SUNSCREEN CREAM CONTAINING PONGAMIA PINNATA LEAVES AND PUNICA GRANATUM PEEL EXTRACT BY HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY , 2015 .

[20]  N. Akhtar,et al.  Development of Skin-friendly Dermatological Water-in-Oil Emulsion of Pomegranate Juice , 2012 .

[21]  Sakshi Ahuja,et al.  A comparative evaluation of efficacy of Punica granatum and chlorhexidine on plaque and gingivitis , 2011 .