Neurofilaments at a glance
暂无分享,去创建一个
Veeranna | Aidong Yuan | R. Nixon | Ralph A Nixon | Mala V Rao | M. Rao | A. Yuan
[1] Sangmook Lee,et al. Interference with kinesin‐based anterograde neurofilament axonal transport increases neurofilament‐neurofilament bundling , 2012, Cytoskeleton.
[2] H. Pant,et al. Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[3] Veeranna,et al. Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments , 2011, Neurobiology of Aging.
[4] P. Suh,et al. Phosphatidylinositol phosphates directly bind to neurofilament light chain (NF-L) for the regulation of NF-L self assembly , 2011, Experimental & Molecular Medicine.
[5] Veeranna,et al. The Myosin Va Head Domain Binds to the Neurofilament-L Rod and Modulates Endoplasmic Reticulum (ER) Content and Distribution within Axons , 2011, PloS one.
[6] R. Nixon,et al. Axonal Transport Mechanisms in Cytoskeleton Formation and Regulation , 2011 .
[7] Anthony Brown,et al. A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport , 2010, Molecular Neurodegeneration.
[8] Sangmook Lee,et al. Aluminum induces neurofilament aggregation by stabilizing cross-bridging of phosphorylated c-terminal sidearms , 2010, Brain Research.
[9] M. Strong,et al. Post-transcriptional control of neurofilaments: New roles in development, regeneration and neurodegenerative disease , 2010, Trends in Neurosciences.
[10] S. Scherer,et al. A novel recessive Nefl mutation causes a severe, early‐onset axonal neuropathy , 2009, Annals of neurology.
[11] Anthony Brown,et al. Tight functional coupling of kinesin-1A and dynein motors in the bidirectional transport of neurofilaments. , 2009, Molecular biology of the cell.
[12] R. Perrot,et al. Neuronal intermediate filaments and neurodegenerative disorders , 2009, Brain Research Bulletin.
[13] Sangmook Lee,et al. Neurofilament cross-bridging competes with kinesin-dependent association of neurofilaments with microtubules , 2009, Journal of Cell Science.
[14] Vivek V. Kanumuri,et al. Neurofilaments Form a Highly Stable Stationary Cytoskeleton after Reaching a Critical Level in Axons , 2009, The Journal of Neuroscience.
[15] R. Berges,et al. Neurofilaments Bind Tubulin and Modulate Its Polymerization , 2009, The Journal of Neuroscience.
[16] Peter Jung,et al. Myosin Va Increases the Efficiency of Neurofilament Transport by Decreasing the Duration of Long-Term Pauses , 2009, The Journal of Neuroscience.
[17] C. Shaw,et al. Neurofilament subunit (NFL) head domain phosphorylation regulates axonal transport of neurofilaments. , 2009, European journal of cell biology.
[18] Sameer B. Shah,et al. Phosphorylation of Highly Conserved Neurofilament Medium KSP Repeats Is Not Required for Myelin-Dependent Radial Axonal Growth , 2009, The Journal of Neuroscience.
[19] Kayoko Saito,et al. Neurofilament light chain polypeptide gene mutations in Charcot–Marie–Tooth disease: nonsense mutation probably causes a recessive phenotype , 2009, Journal of Human Genetics.
[20] Dong-xia Wu,et al. Alternation of neurofilaments in immune-mediated injury of spinal cord motor neurons , 2009, Spinal Cord.
[21] P. Gruss,et al. Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration , 2008, Proceedings of the National Academy of Sciences.
[22] R. Berges,et al. Review of the Multiple Aspects of Neurofilament Functions, and their Possible Contribution to Neurodegeneration , 2008, Molecular Neurobiology.
[23] C. Shaw,et al. Deregulation of PKN1 activity disrupts neurofilament organisation and axonal transport , 2008, FEBS letters.
[24] I. Grundke‐Iqbal,et al. Regulation between O‐GlcNAcylation and phosphorylation of neurofilament‐M and their dysregulation in Alzheimer disease , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[25] R. Perrot,et al. Axonal Neurofilaments Control Multiple Fiber Properties But Do Not Influence Structure or Spacing of Nodes of Ranvier , 2007, The Journal of Neuroscience.
[26] Sebastian Rammensee,et al. Softness, strength and self-repair in intermediate filament networks. , 2007, Experimental cell research.
[27] Jean-Pierre Julien,et al. Conditional NF-L Transgene Expression in Mice for In Vivo Analysis of Turnover and Transport Rate of Neurofilaments , 2007, The Journal of Neuroscience.
[28] Anthony Brown,et al. The polypeptide composition of moving and stationary neurofilaments in cultured sympathetic neurons. , 2007, Cell motility and the cytoskeleton.
[29] Peter Jung,et al. Neurofilaments Switch between Distinct Mobile and Stationary States during Their Transport along Axons , 2007, The Journal of Neuroscience.
[30] Veeranna,et al. α-Internexin Is Structurally and Functionally Associated with the Neurofilament Triplet Proteins in the Mature CNS , 2006, The Journal of Neuroscience.
[31] Jonathan C Trinidad,et al. O-Linked N-Acetylglucosamine Proteomics of Postsynaptic Density Preparations Using Lectin Weak Affinity Chromatography and Mass Spectrometry*S , 2006, Molecular & Cellular Proteomics.
[32] T. Gotow,et al. Aggregate formation and phosphorylation of neurofilament-L Pro22 Charcot-Marie-Tooth disease mutants. , 2006, Human molecular genetics.
[33] R. Nixon,et al. Deleting the phosphorylated tail domain of the neurofilament heavy subunit does not alter neurofilament transport rate in vivo , 2006, Neuroscience Letters.
[34] P. Janmey,et al. Regulation of neurofilament interactionsin vitro by natural and synthetic polypeptides sharing Lys-Ser-Pro sequences with the heavy neurofilament subunit NF-H: Neurofilament crossbridging by antiparallel sidearm overlapping , 1998, Medical and Biological Engineering and Computing.
[35] Sangmook Lee,et al. The high and middle molecular weight neurofilament subunits regulate the association of neurofilaments with kinesin: inhibition by phosphorylation of the high molecular weight subunit. , 2005, Brain research. Molecular brain research.
[36] M. Docquier,et al. No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse model. , 2005, Human molecular genetics.
[37] Anthony Brown,et al. Neurofilament Polymer Transport in Axons , 2005, The Journal of Neuroscience.
[38] M. Black,et al. Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments , 2005, The Journal of cell biology.
[39] F. Liu,et al. Post-translational modifications of tau protein in Alzheimer’s disease , 2005, Journal of Neural Transmission.
[40] P. Janmey,et al. The interaction of neurofilaments with the microtubule motor cytoplasmic dynein. , 2004, Molecular biology of the cell.
[41] Veeranna,et al. Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease. , 2004, The American journal of pathology.
[42] Jonathan D Cooper,et al. p38α stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis , 2004, Molecular and Cellular Neuroscience.
[43] Neurobiology Program. Slow axonal transport : the polymer transport model , 2004 .
[44] Sameer B. Shah,et al. NF-M is an essential target for the myelin-directed “outside-in” signaling cascade that mediates radial axonal growth , 2003, The Journal of cell biology.
[45] T. Gotow,et al. The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate , 2003, The Journal of cell biology.
[46] G. Elder,et al. Human midsized neurofilament subunit induces motor neuron disease in transgenic mice , 2003, Experimental Neurology.
[47] J. Julien,et al. Neurofilament Transport In Vivo Minimally Requires Hetero-Oligomer Formation , 2003, The Journal of Neuroscience.
[48] C. Shaw,et al. Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments , 2003, The Journal of cell biology.
[49] Xinran Liu,et al. Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A , 2003, The Journal of cell biology.
[50] Ammar Al-Chalabi,et al. Neurofilaments and neurological disease. , 2003, BioEssays : news and reviews in molecular, cellular and developmental biology.
[51] N. Calcutt,et al. Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport , 2002, The Journal of cell biology.
[52] D. Sibley,et al. Neurofilament-M Interacts with the D1 Dopamine Receptor to Regulate Cell Surface Expression and Desensitization , 2002, The Journal of Neuroscience.
[53] H. Pant,et al. Myelin‐associated glycoprotein modulates expression and phosphorylation of neuronal cytoskeletal elements and their associated kinases , 2002, Journal of neurochemistry.
[54] M. Polymeropoulos,et al. A mutation in the human neurofilament M gene in Parkinson's disease that suggests a role for the cytoskeleton in neuronal degeneration , 2002, Neuroscience Letters.
[55] M. Cobb,et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. , 2001, Endocrine reviews.
[56] H. Pant,et al. Integrins stimulate phosphorylation of neurofilament NF‐M subunit KSP repeats through activation of extracellular regulated‐kinases (Erk1/Erk2) in cultured motoneurons and transfected NIH 3T3 cells , 2001, Journal of neurochemistry.
[57] Xiongwei Zhu,et al. Activation and redistribution of c‐Jun N‐terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease , 2001, Journal of neurochemistry.
[58] Sangmook Lee,et al. The predominant form in which neurofilament subunits undergo axonal transport varies during axonal initiation, elongation, and maturation. , 2001, Cell motility and the cytoskeleton.
[59] Jean-Pierre Julien,et al. Electrophysiological properties of axons in mice lacking neurofilament subunit genes: disparity between conduction velocity and axon diameter in absence of NF-H , 2000, Brain Research.
[60] Ram K. Sihag,et al. Local Control of Neurofilament Accumulation during Radial Growth of Myelinating Axons in Vivo , 2000, The Journal of cell biology.
[61] B. Helfand,et al. Fast transport of neurofilament protein along microtubules in squid axoplasm. , 2000, Journal of cell science.
[62] P. Janmey,et al. Bidirectional translocation of neurofilaments along microtubules mediated in part by dynein/dynactin. , 2000, Molecular biology of the cell.
[63] Scott T. Brady,et al. Neurofilaments Are Transported Rapidly But Intermittently in Axons: Implications for Slow Axonal Transport , 2000, The Journal of Neuroscience.
[64] S. Komai,et al. Site‐Specific Phosphorylation of Neurofilament‐L Is Mediated by Calcium/Calmodulin‐Dependent Protein Kinase II in the Apical Dendrites During Long‐Term Potentiation , 2000, Journal of neurochemistry.
[65] T B Shea,et al. Phospho-dependent association of neurofilament proteins with kinesin in situ. , 2000, Cell motility and the cytoskeleton.
[66] Lei Wang,et al. Rapid movement of axonal neurofilaments interrupted by prolonged pauses , 2000, Nature Cell Biology.
[67] T B Shea,et al. Kinesin-mediated transport of neurofilament protein oligomers in growing axons. , 1999, Journal of cell science.
[68] T. Reese,et al. Slow transport of unpolymerized tubulin and polymerized neurofilament in the squid giant axon. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[69] Veeranna,et al. Calcium influx and membrane depolarization induce phosphorylation of neurofilament (NF-M) KSP repeats in PC12 cells. , 1999, Brain research. Molecular brain research.
[70] Veeranna,et al. Activation of mitogen-activated protein kinases (Erk1 and Erk2) cascade results in phosphorylation of NF-M tail domains in transfected NIH 3T3 cells. , 1999, European journal of biochemistry.
[71] R. Nixon,et al. Serine‐23 Is a Major Protein Kinase A Phosphorylation Site on the Amino‐Terminal Head Domain of the Middle Molecular Mass Subunit of Neurofilament Proteins , 1999, Journal of neurochemistry.
[72] J. Julien,et al. Interactions between peripherin and neurofilaments in cultured cells: disruption of peripherin assembly by the NF-M and NF-H subunits. , 1999, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[73] Robert D. Goldman,et al. Rapid Movements of Vimentin on Microtubule Tracks: Kinesin-dependent Assembly of Intermediate Filament Networks , 1998, The Journal of cell biology.
[74] Q. Zhu,et al. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[75] Q. Zhu,et al. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[76] Veeranna,et al. Mitogen-Activated Protein Kinases (Erk1,2) Phosphorylate Lys-Ser-Pro (KSP) Repeats in Neurofilament Proteins NF-H and NF-M , 1998, The Journal of Neuroscience.
[77] P. Bosco,et al. Absence of the Mid-sized Neurofilament Subunit Decreases Axonal Calibers, Levels of Light Neurofilament (NF-L), and Neurofilament Content , 1998, The Journal of cell biology.
[78] Veeranna,et al. Characterization of the phosphorylation sites of human high molecular weight neurofilament protein by electrospray ionization tandem mass spectrometry and database searching. , 1998, Biochemistry.
[79] Virginia M. Y. Lee,et al. Myelin-Associated Glycoprotein Is a Myelin Signal that Modulates the Caliber of Myelinated Axons , 1998, The Journal of Neuroscience.
[80] K. Konvička,et al. Neurofilament (NF) Assembly; Divergent Characteristics of Human and Rodent NF-L Subunits* , 1998, The Journal of Biological Chemistry.
[81] R. Huganir,et al. Splice Variant-Specific Interaction of the NMDA Receptor Subunit NR1 with Neuronal Intermediate Filaments , 1998, The Journal of Neuroscience.
[82] L. WilliamsonT,et al. 神経フィラメントの欠如は,家族性筋萎縮性側索硬化症関連スーパオキジドジスムターゼ1変異に対する運動ニューロンの選択的易損性を低下させ,疾患を遅らせる , 1998 .
[83] B. Giasson,et al. Study of Proline-Directed Protein Kinases Involved in Phosphorylation of the Heavy Neurofilament Subunit , 1997, The Journal of Neuroscience.
[84] J. Julien,et al. Delayed Maturation of Regenerating Myelinated Axons in Mice Lacking Neurofilaments , 1997, Experimental Neurology.
[85] F. Ebner,et al. Protein serine/threonine phosphatase 1 and 2A associate with and dephosphorylate neurofilaments. , 1997, Brain research. Molecular brain research.
[86] N. Hirokawa,et al. Slow axonal transport: the subunit transport model. , 1997, Trends in cell biology.
[87] G. Hart,et al. Cytoplasmic O-GlcNAc Modification of the Head Domain and the KSP Repeat Motif of the Neurofilament Protein Neurofilament-H* , 1996, The Journal of Biological Chemistry.
[88] R. Liem,et al. Phosphorylation of the High Molecular Weight Neurofilament Protein (NF-H) by Cdk5 and p35* , 1996, The Journal of Biological Chemistry.
[89] I. Grundke‐Iqbal,et al. Phosphatase Activity Toward Abnormally Phosphorylated τ: Decrease in Alzheimer Disease Brain , 1995, Journal of neurochemistry.
[90] M. Nagao,et al. Neurofilament-associated protein phosphatase 2A: its possible role in preserving neurofilaments in filamentous states. , 1995, Biochemistry.
[91] Veeranna,et al. Neuronal Cyclin‐Dependent Kinase‐5 Phosphorylation Sites in Neurofilament Protein (NF‐H) Are Dephosphorylated by Protein Phosphatase 2A , 1995, Journal of neurochemistry.
[92] Steven H Y Hsieh,et al. Regional modulation of neurofilament organization by myelination in normal axons , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[93] R. Nixon,et al. Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber , 1994, The Journal of cell biology.
[94] A. Peterson,et al. Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-β-galactosidase fusion protein , 1994, Neuron.
[95] M. Inagaki,et al. Phosphorylation of a 62-kd Porcine α-Internexin, a Newly Identified Intermediate Filament Protein , 1993 .
[96] I. Grundke‐Iqbal,et al. Phosphoprotein Phosphatase Activities in Alzheimer Disease Brain , 1993, Journal of neurochemistry.
[97] H. Pant,et al. cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[98] T. Sakaguchi,et al. Reduced diameter and conduction velocity of myelinated fibers in the sciatic nerve of a neurofilament-deficient mutant quail , 1993, Neuroscience Letters.
[99] J. Julien,et al. Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis , 1993, Cell.
[100] O. Ohara,et al. Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene , 1993, The Journal of cell biology.
[101] M. Inagaki,et al. Phosphorylation of a 62 kd porcine alpha-internexin, a newly identified intermediate filament protein. , 1993, Biochemical and Biophysical Research Communications - BBRC.
[102] R. Lasek,et al. Slow axonal transport mechanisms move neurofilaments relentlessly in mouse optic axons , 1992, The Journal of cell biology.
[103] Z. S. Xu,et al. Identification of six phosphorylation sites in the COOH-terminal tail region of the rat neurofilament protein M. , 1992, The Journal of biological chemistry.
[104] D. Fink,et al. Phosphorylation-dependent neurofilament epitopes are reduced at the node of Ranvier , 1992, Journal of neurocytology.
[105] Scott T. Brady,et al. Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells , 1992, Cell.
[106] R. Nixon,et al. Dynamics of neuronal intermediate filaments: a developmental perspective. , 1992, Cell motility and the cytoskeleton.
[107] T. Kishimoto,et al. Phosphorylation of neurofilament H subunit at the tail domain by CDC2 kinase dissociates the association to microtubules. , 1991, The Journal of biological chemistry.
[108] R. Nixon,et al. Identification of Ser-55 as a major protein kinase A phosphorylation site on the 70-kDa subunit of neurofilaments. Early turnover during axonal transport. , 1991, The Journal of biological chemistry.
[109] R. Friede,et al. Axonal cytoskeleton at the nodes of Ranvier , 1991, Journal of neurocytology.
[110] Ram K. Sihag,et al. Phosphorylation of the amino-terminal head domain of the middle molecular mass 145-kDa subunit of neurofilaments. Evidence for regulation by second messenger-dependent protein kinases. , 1990, The Journal of biological chemistry.
[111] N. Hirokawa,et al. Effects of phosphorylation of the neurofilament L protein on filamentous structures. , 1990, Cell regulation.
[112] U. Dräger,et al. Early posttranslational modifications of the three neurofilament subunits in mouse retinal ganglion cells: neuronal sites and time course in relation to subunit polymerization and axonal transport. , 1989, Brain research. Molecular brain research.
[113] N. Hirokawa,et al. The effects of dephosphorylation on the structure of the projections of neurofilament , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[114] R. Nixon,et al. In vivo phosphorylation of distinct domains of the 70-kilodalton neurofilament subunit involves different protein kinases. , 1989, The Journal of biological chemistry.
[115] H. Pant. Dephosphorylation of neurofilament proteins enhances their susceptibility to degradation by calpain. , 1988, The Biochemical journal.
[116] J. Eyer,et al. Influence of the phosphorylation state of neurofilament proteins on the interactions between purified filaments in vitro. , 1988, The Biochemical journal.
[117] R. Nixon,et al. Phosphorylation of neurofilament proteins by protein kinase C , 1988, FEBS letters.
[118] L. Otvos,et al. Identification of the major multiphosphorylation site in mammalian neurofilaments. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[119] D. Perl,et al. Accumulation of Phosphorylated Neurofilaments in Anterior Horn Motoneurons of Amyotrophic Lateral Sclerosis Patients , 1988, Journal of neuropathology and experimental neurology.
[120] L. Pradel,et al. Binding of brain spectrin to the 70-kDa neurofilament subunit protein. , 1987, European journal of biochemistry.
[121] J. Trojanowski,et al. Two-stage expression of neurofilament polypeptides during rat neurogenesis with early establishment of adult phosphorylation patterns , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[122] J. Trojanowski,et al. Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[123] J. Vandekerckhove,et al. Location and sequence characterization of the major phosphorylation sites of the high molecular mass neurofilament proteins M and H , 1987, FEBS letters.
[124] J W Griffin,et al. Neurofilament gene expression: a major determinant of axonal caliber. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[125] C. Marotta,et al. Posttranslational modification of neurofilament proteins by phosphate during axoplasmic transport in retinal ganglion cell neurons , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[126] R. Nixon,et al. Differential turnover of phosphate groups on neurofilament subunits in mammalian neurons in vivo. , 1986, The Journal of biological chemistry.
[127] R. Nixon,et al. Multiple fates of newly synthesized neurofilament proteins: evidence for a stationary neurofilament network distributed nonuniformly along axons of retinal ganglion cell neurons , 1986, The Journal of cell biology.
[128] R. Lasek,et al. Axonal transport of the cytoplasmic matrix , 1984, The Journal of cell biology.
[129] J. Pachter,et al. The differential appearance of neurofilament triplet polypeptides in the developing rat optic nerve. , 1984, Developmental biology.
[130] L. Sternberger,et al. Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[131] J. Julien,et al. The distribution of phosphorylation sites among identified proteolytic fragments of mammalian neurofilaments. , 1983, The Journal of biological chemistry.
[132] R. Friede,et al. Axon caliber related to neurofilaments and microtubules in sciatic nerve fibers of rats and mice , 1970, The Anatomical record.