Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine

[1]  K. Wilcox,et al.  Impaired cognitive ability and anxiety-like behavior following acute seizures in the Theiler's virus model of temporal lobe epilepsy , 2014, Neurobiology of Disease.

[2]  Avishek Adhikari,et al.  Behavioral Neuroscience Mini Review Article Distributed Circuits Underlying Anxiety , 2022 .

[3]  Aurel Popa-Wagner,et al.  HIV-associated neurocognitive disorders , 2014, Journal of molecular psychiatry.

[4]  K. Luan Phan,et al.  The contextual brain: implications for fear conditioning, extinction and psychopathology , 2013, Nature Reviews Neuroscience.

[5]  B. Slusher,et al.  Targeting the Glutamatergic System for the Treatment of HIV-Associated Neurocognitive Disorders , 2013, Journal of Neuroimmune Pharmacology.

[6]  T. Krahe,et al.  Synaptic Dysfunction in the Hippocampus Accompanies Learning and Memory Deficits in Human Immunodeficiency Virus Type-1 Tat Transgenic Mice , 2013, Biological Psychiatry.

[7]  Adam B. Cohen,et al.  Eastern Equine Encephalitis in Children, Massachusetts and New Hampshire,USA, 1970–2010 , 2013, Emerging infectious diseases.

[8]  H. van Praag,et al.  Running throughout middle‐age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL/6J mice , 2012, Developmental neurobiology.

[9]  Rodney W. Johnson,et al.  Influenza Infection Induces Neuroinflammation, Alters Hippocampal Neuron Morphology, and Impairs Cognition in Adult Mice , 2012, The Journal of Neuroscience.

[10]  D. Green,et al.  The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. , 2011, Immunity.

[11]  D. Griffin,et al.  Alphavirus-Induced Encephalomyelitis: Antibody-Secreting Cells and Viral Clearance from the Nervous System , 2011, Journal of Virology.

[12]  E. Kroon,et al.  Intracerebral infection with dengue-3 virus induces meningoencephalitis and behavioral changes that precede lethality in mice , 2011, Journal of Neuroinflammation.

[13]  H. van Praag,et al.  Exercise is not beneficial and may accelerate symptom onset in a mouse model of Huntington’s disease , 2010, PLoS currents.

[14]  T. Seyfried,et al.  Glutamine targeting inhibits systemic metastasis in the VM‐M3 murine tumor model , 2010, International journal of cancer.

[15]  S. Moncada,et al.  Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes , 2010, Proceedings of the National Academy of Sciences.

[16]  B. Barak,et al.  Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis , 2010, Proceedings of the National Academy of Sciences.

[17]  J. McArthur,et al.  Human immunodeficiency virus‐associated neurocognitive disorders: Mind the gap , 2010, Annals of neurology.

[18]  T. Scott,et al.  Consequences of the Expanding Global Distribution of Aedes albopictus for Dengue Virus Transmission , 2010, PLoS neglected tropical diseases.

[19]  S. Weaver,et al.  Present and future arboviral threats. , 2010, Antiviral research.

[20]  D. Griffin.  Emergence and re-emergence of viral diseases of the central nervous system , 2009, Progress in Neurobiology.

[21]  B. Kieffer,et al.  Activation of nociceptin opioid peptide (NOP) receptor impairs contextual fear learning in mice through glutamatergic mechanisms , 2009, Neurobiology of Learning and Memory.

[22]  G. Gronvall.  Medical Aspects of Biological Warfare Edited by Zygmunt F. Dembek Falls Church, Virginia: Office of The Surgeon General, United States Army; Washington, DC: Borden Institute, Walter Reed Army Medical Center, 2007. 694 pp., Illustrated. $72.25 (hardcover) , 2009 .

[23]  A. Suzumura,et al.  Blockade of glutamate release from microglia attenuates experimental autoimmune encephalomyelitis in mice. , 2009, The Tohoku journal of experimental medicine.

[24]  S. Ritchie,et al.  Ecology and geographical expansion of Japanese encephalitis virus. , 2009, Annual review of entomology.

[25]  L. White,et al.  Extrahippocampal involvement in human herpesvirus 6 encephalitis depicted at MR imaging. , 2008, Radiology.

[26]  D. Griffin,et al.  Protection from fatal viral encephalomyelitis: AMPA receptor antagonists have a direct effect on the inflammatory response to infection , 2008, Proceedings of the National Academy of Sciences.

[27]  J Gordon Millichap,et al.  Etiologic Classification of Attention-Deficit/Hyperactivity Disorder , 2008, Pediatrics.

[28]  Jacqueline N. Crawley,et al.  What's Wrong With My Mouse? , 2007 .

[29]  A. Savonenko,et al.  Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer’s disease in a sex-dimorphic pattern , 2006, Neuroscience.

[30]  M. Jung,et al.  Neural circuits and mechanisms involved in Pavlovian fear conditioning: A critical review , 2006, Neuroscience & Biobehavioral Reviews.

[31]  Brian J. Wiltgen,et al.  Context Fear Learning in the Absence of the Hippocampus , 2006, The Journal of Neuroscience.

[32]  L. Mofenson,et al.  A Behavioral and Cognitive Profile of Clinically Stable HIV-Infected Children , 2006, Pediatrics.

[33]  M. Bigal.  Glutamate Receptor Antagonists , 2004 .

[34]  J. Rothstein,et al.  Glutamate receptor antagonists protect from virus‐induced neural degeneration , 2004, Annals of neurology.

[35]  E. Borden,et al.  Phase II trial of 6-diazo-5-oxo-L-norleucine versus aclacinomycin-A in advanced sarcomas and mesotheliomas , 1990, Investigational New Drugs.

[36]  D. Griffin,et al.  Extensive immune-mediated hippocampal damage in mice surviving infection with neuroadapted Sindbis virus. , 2003, Virology.

[37]  Brian J. Wiltgen,et al.  The place of the hippocampus in fear conditioning. , 2003, European journal of pharmacology.

[38]  M. McCarthy,et al.  MK-801 disrupts acquisition of contextual fear conditioning but enhances memory consolidation of cued fear conditioning , 2002, Behavioural pharmacology.

[39]  D. Gubler.  The global emergence/resurgence of arboviral diseases as public health problems. , 2002, Archives of medical research.

[40]  M. Medina,et al.  Glutamine and cancer. , 2001, The Journal of nutrition.

[41]  D. Griffin,et al.  Interferon-γ-Mediated Site-Specific Clearance of Alphavirus from CNS Neurons , 2001, Science.

[42]  D. Griffin,et al.  Activation of Divergent Neuronal Cell Death Pathways in Different Target Cell Populations during Neuroadapted Sindbis Virus Infection of Mice , 2000, Journal of Virology.

[43]  Jacqueline N. Crawley,et al.  What's Wrong With My Mouse?: Behavioral Phenotyping of Transgenic and Knockout Mice , 2000 .

[44]  Stephen Maren,et al.  Muscimol Inactivation of the Dorsal Hippocampus Impairs Contextual Retrieval of Fear Memory , 1999, The Journal of Neuroscience.

[45]  D. Griffin,et al.  The inflammatory response to nonfatal Sindbis virus infection of the nervous system is more severe in SJL than in BALB/c mice and is associated with low levels of IL-4 mRNA and high levels of IL-10-producing CD4+ T cells. , 1999, Journal of immunology.

[46]  R. Paylor,et al.  Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task. , 1997, Behavioral neuroscience.

[47]  R. Rico-Hesse,et al.  Re-emergence of epidemic Venezuelan equine encephalomyelitis in South America , 1996, The Lancet.

[48]  A. Spielman,et al.  The economic burden imposed by a residual case of eastern encephalitis. , 1995, The American journal of tropical medicine and hygiene.

[49]  Joseph E LeDoux,et al.  Lesions of the dorsal hippocampal formation interfere with background but not foreground contextual fear conditioning. , 1994, Learning & memory.

[50]  W W Souba,et al.  Glutamine and Cancer , 1993, Annals of surgery.

[51]  J. W. Rudy,et al.  Contextual conditioning and auditory cue conditioning dissociate during development. , 1993, Behavioral neuroscience.

[52]  D. Griffin,et al.  Persistence of viral RNA in mouse brains after recovery from acute alphavirus encephalitis , 1992, Journal of virology.

[53]  Joseph E LeDoux,et al.  Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. , 1992, Behavioral neuroscience.

[54]  T. Crawford,et al.  Antibody-mediated clearance of alphavirus infection from neurons. , 1991, Science.

[55]  J. H. Strauss,et al.  Molecular basis of Sindbis virus neurovirulence in mice , 1988, Journal of virology.

[56]  D. Griffin,et al.  The pathogenesis of spinal cord involvement in the encephalomyelitis of mice caused by neuroadapted Sindbis virus infection. , 1987, Laboratory investigation; a journal of technical methods and pathology.

[57]  S Marsoni,et al.  The phase II trial. , 1985, Cancer treatment reports.

[58]  B. Crabtree,et al.  Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance. , 1985, Quarterly journal of experimental physiology.

[59]  J. Bender,et al.  Phase I Trial , 1983 .

[60]  J. Koeller,et al.  Phase I trial of 6-diazo-5-oxo-L-norleucine (DON) administered by 5-day courses. , 1982, Cancer treatment reports.

[61]  J. Kovach,et al.  Phase I and pharmacokinetic studies of DON. , 1981, Cancer treatment reports.

[62]  E. Casper,et al.  Phase I study of 6-diazo-5-oxo-L-norleucine (DON). , 1980, Cancer treatment reports.

[63]  J. Olney,et al.  Acute dendrotoxic changes in the hippocampus of kainate treated rats , 1979, Brain Research.

[64]  C. Cotman,et al.  Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells , 1978, Nature.

[65]  M. Earnest,et al.  Neurologic, intellectual, and psychologic sequelae following western encephalitis , 1971, Neurology.

[66]  A. Baker,et al.  [Western equine encephalitis]. , 1958, Neurology.

[67]  R. E. Cook,et al.  Western Equine and St. Louis Encephalitis , 1955, Neurology.

[68]  E. H. Lennette,et al.  Western equine encephalitis in infants; a report on three cases with sequelae. , 1953, California medicine.