Multiple effects of 3,4,5,3',4',5'-hexachlorobiphenyl administration on hepatic cytochrome P450 isozymes and associated mixed-function oxidase activities in rainbow trout.

[1]  C. Miranda,et al.  Immunological characterization of constitutive isozymes of cytochrome P-450 from rainbow trout. Evidence for homology with phenobarbital-induced rat P-450s. , 1990, Biochimica et biophysica acta.

[2]  M. E. Hahn,et al.  Effects of ortho- and non-ortho-substituted polychlorinated biphenyl congeners on the hepatic monooxygenase system in scup (Stenotomus chrysops). , 1989, Toxicology and applied pharmacology.

[3]  D. Nebert,et al.  Trout P450IA1: cDNA and deduced protein sequence, expression in liver, and evolutionary significance. , 1988, DNA.

[4]  J. Goldstein,et al.  Suppression of the constitutive, male-specific rat hepatic cytochrome P-450 2c and its mRNA by 3,4,5,3',4',5'-hexachlorobiphenyl and 3-methylcholanthrene. , 1987, Molecular pharmacology.

[5]  S. Aust,et al.  Specific binding of polyhalogenated aromatic hydrocarbon inducers of cytochrome P-450d to the cytochrome and inhibition of its estradiol 2-hydroxylase activity. , 1987, Toxicology and applied pharmacology.

[6]  J. Goldstein,et al.  Dose response for induction of two cytochrome P-450 isozymes and their mRNAs by 3,4,5,3'4'5'-hexachlorobiphenyl indicating coordinate regulation in rat liver. , 1985, Molecular pharmacology.

[7]  T. Kamataki,et al.  Metabolism and activation of aflatoxin B1 by reconstituted cytochrome P-450 system of rat liver. , 1980, Cancer research.

[8]  J. Hendricks,et al.  Inhibitory effect of a polychlorinated biphenyl (Aroclor 1254) on aflatoxin B1 carcinogenesis in rainbow trout (Salmo gairdneri). , 1977, Journal of the National Cancer Institute.

[9]  Oliver H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[10]  C. Miranda,et al.  Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout. , 1989, Archives of biochemistry and biophysics.

[11]  David E. Williams,et al.  The role of biotransformation in the toxicity of chemicals , 1988 .

[12]  J. Schenkman,et al.  Isolation and comparison of four cytochrome P-450 enzymes from phenobarbital-induced rat liver: three forms possessing identical NH2-terminal sequences. , 1985, Pharmacology.

[13]  S. Safe.  Polychlorinated biphenyls (PCBs) and polybrominated biphenyls (PBBs): biochemistry, toxicology, and mechanism of action. , 1984, Critical reviews in toxicology.

[14]  J. Depierre,et al.  [44] Radioactive assay of aryl hydrocarbon monooxygenase and expoxide hydrase , 1978 .

[15]  R. Estabrook,et al.  The Spectrophotometric Measurement of Turbid Suspensions of Cytochromes Associated with Drug Metabolism , 1972 .