Laser-Tissue Interactions in the Nanosecond, Picosecond and Femtosecond Time Domains

The use of high peak power laser pulses in the short and ultrashort time domains has opened a variety of novel laser-tissue interactions with potential for application in clinical medicine. Photodisruption (optical breakdown) of nominally transparent tissues within the eye, excimer laser tissue ablation, and femtosecond laser tissue ablation are three examples of such tissue effects. Laser tissue interactions in these time domains will be reviewed and selected techniques for investigation of the time scale and damage mechanisms of these interactions will be presented.

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