Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice.
暂无分享,去创建一个
[1] R. G. Lloyd. The segregation of the SbcA and Rac phenotypes in an Escherichia coli recB− mutant , 2004, Molecular and General Genetics MGG.
[2] Shiaoching Gong,et al. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes , 2003, Nature.
[3] Bin Liu,et al. Functional genetic analysis of mouse chromosome 11 , 2003, Nature.
[4] Philippe Soriano,et al. Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation , 2003, Nature Genetics.
[5] Franz Vauti,et al. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[6] A. Bradley,et al. Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p , 2003, Genesis.
[7] A. F. Stewart,et al. High-throughput engineering of the mouse genome coupled with high-resolution expression analysis , 2003, Nature Biotechnology.
[8] Daiguan Yu,et al. Recombineering with overlapping single-stranded DNA oligonucleotides: Testing a recombination intermediate , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[9] A. Graham,et al. The neural crest , 2003, Current Biology.
[10] J. Lupski,et al. Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) Contiguous Gene Syndromes by Chromosome Engineering in Mice: Phenotypic Consequences of Gene Dosage Imbalance , 2003, Molecular and Cellular Biology.
[11] B. Seed,et al. Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes , 2003, Nature Biotechnology.
[12] V. Beneš,et al. Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles , 2003, Nature Biotechnology.
[13] P. Chambon,et al. A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse , 2003, Nature Biotechnology.
[14] M. Giovannini,et al. Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles. , 2003, Nucleic acids research.
[15] D. Ow,et al. Site-specific cassette exchange and germline transmission with mouse ES cells expressing φC31 integrase , 2003, Nature Biotechnology.
[16] N. Copeland,et al. A highly efficient recombineering-based method for generating conditional knockout mutations. , 2003, Genome research.
[17] Rudolf Jaenisch,et al. Rapid generation of inducible mouse mutants. , 2003, Nucleic acids research.
[18] Jay H. Konieczka,et al. Stepwise manipulation of DNA specificity in Flp recombinase: progressively adapting Flp to individual and combinatorial mutations in its target site. , 2003, Journal of molecular biology.
[19] K. Novak,et al. From mouse to man , 2003, Nature Reviews Cancer.
[20] A. F. Stewart,et al. High-throughput engineering of the mouse genome coupled with high-resolution expression analysis , 2003, Nature Biotechnology.
[21] Conrad C. Huang,et al. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells , 2003, Nucleic Acids Res..
[22] Colin N. Dewey,et al. Initial sequencing and comparative analysis of the mouse genome. , 2002 .
[23] K. Rajewsky,et al. Stringent doxycycline dependent control of CRE recombinase in vivo. , 2002, Nucleic acids research.
[24] Shiaoching Gong,et al. Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication. , 2002, Genome research.
[25] K. Chien,et al. Normal fate and altered function of the cardiac neural crest cell lineage in retinoic acid receptor mutant embryos , 2002, Mechanisms of Development.
[26] L. Leinwand,et al. A genetic screen identifies novel non-compatible loxP sites. , 2002, Nucleic acids research.
[27] David J Anderson,et al. Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[28] Y. Wan,et al. Identification of genes differentially regulated by glucocorticoids and progestins using a Cre/loxP-mediated retroviral promoter-trapping strategy. , 2002, Journal of molecular endocrinology.
[29] Andrew P McMahon,et al. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. , 2002, Developmental biology.
[30] K. Rajewsky,et al. Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: A tool for efficient genetic engineering of mammalian genomes , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[31] Peter G Schultz,et al. Directed evolution of the site specificity of Cre recombinase , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[32] Susumu Tonegawa,et al. Cre/loxP recombination‐activated neuronal markers in mouse neocortex and hippocampus , 2002, Genesis.
[33] Steve D. M. Brown,et al. A gene-driven approach to the identification of ENU mutants in the mouse , 2002, Nature Genetics.
[34] D. Roop,et al. In utero activation of K5.CrePR1 induces gene deletion , 2002, Genesis.
[35] R. Jaenisch,et al. Flp recombinase regulated lacZ expression at the ROSA26 locus , 2002, Genesis.
[36] M. Justice,et al. Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis , 2002, Nature Genetics.
[37] P. Seeburg,et al. Codon‐improved Cre recombinase (iCre) expression in the mouse , 2002, Genesis.
[38] Caiying Guo,et al. A cre recombinase transgene with mosaic, widespread tamoxifen‐inducible action , 2002, Genesis.
[39] N. Copeland,et al. Efficient Cre-loxP–induced mitotic recombination in mouse embryonic stem cells , 2002, Nature Genetics.
[40] R. Awatramani,et al. Switching on lineage tracers using site-specific recombination. , 2002, Methods in molecular biology.
[41] S. Elledge,et al. Towards genetic genome projects: genomic library screening and gene-targeting vector construction in a single step , 2002, Nature Genetics.
[42] K. Lindblad-Toh,et al. Progress in sequencing the mouse genome , 2001, Genesis.
[43] N. Heintz,et al. Bac to the future: The use of bac transgenic mice for neuroscience research , 2001, Nature Reviews Neuroscience.
[44] Frank Buchholz,et al. Alteration of Cre recombinase site specificity by substrate-linked protein evolution , 2001, Nature Biotechnology.
[45] V. Kaartinen,et al. Removal of the floxed neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo , 2001, Genesis.
[46] Philippe Soriano,et al. An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus , 2001, Nature Genetics.
[47] J. Bode,et al. Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes. , 2001, Current opinion in biotechnology.
[48] A. Bradley,et al. Engineering chromosomal rearrangements in mice , 2001, Nature Reviews Genetics.
[49] W. Stanford,et al. Gene-trap mutagenesis: past, present and beyond , 2001, Nature Reviews Genetics.
[50] A. Berns,et al. Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[51] Paul Scherz,et al. Functional analysis of secreted and transmembrane proteins critical to mouse development , 2001, Nature Genetics.
[52] Eric C. Olivares,et al. Site-Specific Genomic Integration in Mammalian Cells Mediated by Phage φC31 Integrase , 2001, Molecular and Cellular Biology.
[53] A. Bradley,et al. From mouse to man: generating megabase chromosome rearrangements. , 2001, Trends in genetics : TIG.
[54] K. Rajewsky,et al. New variants of inducible Cre recombinase: a novel mutant of Cre-PR fusion protein exhibits enhanced sensitivity and an expanded range of inducibility. , 2001, Nucleic acids research.
[55] A. Bradley,et al. Introducing defined chromosomal rearrangements into the mouse genome. , 2001, Methods.
[56] R. Jaenisch,et al. Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[57] D. Court,et al. A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. , 2001, Genomics.
[58] Jos Jonkers,et al. A highly efficient ligand‐regulated Cre recombinase mouse line shows that LoxP recombination is position dependent , 2001, EMBO reports.
[59] Shankar Srinivas,et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus , 2001, BMC Developmental Biology.
[60] A. Kolb. Selection-Marker-Free Modification of the Murine β-Casein Gene Using a lox2722 Site , 2001 .
[61] M. T. Hasan,et al. Long‐term, noninvasive imaging of regulated gene expression in living mice , 2001, Genesis.
[62] Timothy B. Stockwell,et al. The Sequence of the Human Genome , 2001, Science.
[63] J. V. Moran,et al. Initial sequencing and analysis of the human genome. , 2001, Nature.
[64] D. Roop,et al. An Inducible Mouse Model for Epidermolysis Bullosa Simplex , 2001, Journal of Cell Biology.
[65] D. Roop,et al. Focal Activation of a Mutant Allele Defines the Role of Stem Cells in Mosaic Skin Disorders , 2001, The Journal of cell biology.
[66] P. Chambon,et al. Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[67] K. Willecke,et al. Endothelium‐specific replacement of the connexin43 coding region by a lacZ reporter gene , 2001, Genesis.
[68] Yu Yang,et al. Progress in Sequencing of Rice Genome , 2001 .
[69] A. Appert,et al. Mouse models of human chromosomal translocations and approaches to cancer therapy. , 2001, Blood cells, molecules & diseases.
[70] Y Fujiwara,et al. Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain. , 2001, Blood.
[71] M. Capecchi,et al. Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[72] G. Martin,et al. Fgf8 signalling from the AER is essential for normal limb development , 2000, Nature Genetics.
[73] Giuseppe Testa,et al. DNA cloning by homologous recombination in Escherichia coli , 2000, Nature Biotechnology.
[74] Caiying Guo,et al. Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon cre‐mediated excision , 2000, Genesis.
[75] Philippe Soriano,et al. Widespread recombinase expression using FLPeR (Flipper) mice , 2000, Genesis.
[76] P. Chambon,et al. Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis , 2000, Nature.
[77] V. Beneš,et al. Point mutation of bacterial artificial chromosomes by ET recombination , 2000, EMBO reports.
[78] S. Dymecki,et al. Origin of the Precerebellar System , 2000, Neuron.
[79] E. Simpson,et al. Inter‐chromosomal recombination of Mll and Af9 genes mediated by cre‐loxP in mouse development , 2000, EMBO reports.
[80] A. Trumpp,et al. Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP‐mediated recombination in the mouse , 2000, EMBO reports.
[81] A. Stewart,et al. Creating a transloxation , 2000, EMBO reports.
[82] Klaus Schughart,et al. Genome-wide, large-scale production of mutant mice by ENU mutagenesis , 2000, Nature Genetics.
[83] Steve D. M. Brown,et al. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse , 2000, Nature Genetics.
[84] Reynaldo Sequerra,et al. High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP , 2000, Nature Genetics.
[85] A. Joyner,et al. Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. , 2000, Genes & development.
[86] Eric C. Olivares,et al. A phage integrase directs efficient site-specific integration in human cells. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[87] A. McMahon,et al. Fate of the mammalian cardiac neural crest. , 2000, Development.
[88] A. McMahon,et al. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. , 2000, Development.
[89] A. Nagy,et al. Gene‐trap‐based target site for Cre‐mediated transgenic insertion , 2000, Genesis.
[90] J. Miyazaki,et al. A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre‐mediated recombination , 2000, FEBS letters.
[91] B. Thyagarajan,et al. Mammalian genomes contain active recombinase recognition sites. , 2000, Gene.
[92] A. Bradley,et al. Engineering Mouse Chromosomes with Cre-loxP: Range, Efficiency, and Somatic Applications , 2000, Molecular and Cellular Biology.
[93] D. Schübeler,et al. The Transgeneticists Toolbox: Novel Methods for the Targeted Modification of Eukaryotic Genomes , 2000, Biological chemistry.
[94] A. Bradley,et al. Nested chromosomal deletions induced with retroviral vectors in mice , 2000, Nature Genetics.
[95] S. Tilghman,et al. The temporal requirement for endothelin receptor-B signalling during neural crest development , 1999, Nature.
[96] P Chambon,et al. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. , 1999, Nucleic acids research.
[97] S. Fiering,et al. Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange. , 1999, Journal of molecular biology.
[98] K. Murphy,et al. Roles of RuvC and RecG in Phage λ Red-Mediated Recombination , 1999, Journal of bacteriology.
[99] N. Daigle,et al. Simplified generation of targeting constructs using ET recombination. , 1999, Nucleic acids research.
[100] K. Yamamura,et al. Exchangeable gene trap using the Cre/mutated lox system. , 1999, Cellular and molecular biology.
[101] J. Brennan,et al. Efficient gene-specific expression of Cre recombinase in the mouse embryo by targeted insertion of a novel IRES-Cre cassette into endogenous loci , 1999, Mechanisms of Development.
[102] S. Orkin,et al. Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[103] C. Lobe,et al. Z/AP, a double reporter for cre-mediated recombination. , 1999, Developmental biology.
[104] C. Strathdee,et al. Efficient control of tetracycline-responsive gene expression from an autoregulated bi-directional expression vector. , 1999, Gene.
[105] A. Stewart,et al. Rapid modification of bacterial artificial chromosomes by ET-recombination. , 1999, Nucleic acids research.
[106] A. Bradley,et al. A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice. , 1999, Nucleic acids research.
[107] M. J. Justice,et al. Mouse ENU mutagenesis. , 1999, Human molecular genetics.
[108] Philippe Soriano. Generalized lacZ expression with the ROSA26 Cre reporter strain , 1999, Nature Genetics.
[109] A. McMahon,et al. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase , 1998, Current Biology.
[110] Frank Buchholz,et al. A new logic for DNA engineering using recombination in Escherichia coli , 1998, Nature Genetics.
[111] S. Dymecki,et al. Using Flp-recombinase to characterize expansion of Wnt1-expressing neural progenitors in the mouse. , 1998, Developmental biology.
[112] I. Saito,et al. Role of nucleotide sequences of loxP spacer region in Cre-mediated recombination. , 1998, Gene.
[113] P. Angrand,et al. Improved properties of FLP recombinase evolved by cycling mutagenesis , 1998, Nature Biotechnology.
[114] David J. Anderson,et al. Fate mapping of the mouse midbrain–hindbrain constriction using a site-specific recombination system , 1998, Current Biology.
[115] J. Otte,et al. Selective Disruption of Genes Transiently Induced in Differentiating Mouse Embryonic Stem Cells by Using Gene Trap Mutagenesis and Site-Specific Recombination , 1998, Molecular and Cellular Biology.
[116] K. Murphy,et al. Use of Bacteriophage λ Recombination Functions To Promote Gene Replacement in Escherichia coli , 1998, Journal of bacteriology.
[117] R Kuhn,et al. Temporally and spatially regulated somatic mutagenesis in mice. , 1998, Nucleic acids research.
[118] G. Martin,et al. An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination , 1998, Nature Genetics.
[119] S. O’Gorman,et al. Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[120] J. Vonesch,et al. Spatio-temporally controlled site-specific somatic mutagenesis in the mouse. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[121] J. Mous,et al. Tetracycline-responsive gene expression in mouse brain after amplicon-mediated gene transfer , 1997, Gene Therapy.
[122] N. Heintz,et al. Homologous recombination based modification in Esherichia coli and germline transmission in transgenic mice of a bacterial artificial chromsome , 1997, Nature Biotechnology.
[123] P Chambon,et al. Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. , 1997, Biochemical and biophysical research communications.
[124] B. Sauer,et al. Segmental genomic replacement by Cre-mediated recombination: genotoxic stress activation of the p53 promoter in single-copy transformants. , 1997, Nucleic acids research.
[125] A. Berns,et al. Cre-mediated somatic site-specific recombination in mice. , 1997, Nucleic acids research.
[126] K. Yamamura,et al. Targeted integration of DNA using mutant lox sites in embryonic stem cells. , 1997, Nucleic acids research.
[127] K. Wassarman,et al. Zp3–cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line , 1997, Current Biology.
[128] David J. Anderson,et al. Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain , 1996, Cell.
[129] P. Angrand,et al. Different thermostabilities of FLP and Cre recombinases: implications for applied site-specific recombination. , 1996, Nucleic acids research.
[130] P. Gruss,et al. Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter. , 1996, Nucleic acids research.
[131] P Chambon,et al. Ligand-activated site-specific recombination in mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[132] M. Gossen,et al. Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[133] T. Rülicke,et al. Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[134] S. Dymecki. Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[135] P. Angrand,et al. Regulation of Cre recombinase activity by the synthetic steroid RU 486. , 1996, Nucleic acids research.
[136] A. Bradley,et al. Chromosome engineering in mice , 1995, Nature.
[137] M Aguet,et al. Inducible gene targeting in mice , 1995, Science.
[138] M. Fornerod,et al. Cre-mediated site-specific translocation between nonhomologous mouse chromosomes. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[139] P. Chambon,et al. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[140] R. Beddington,et al. Capturing genes encoding membrane and secreted proteins important for mouse development. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[141] C. Logie,et al. Ligand-regulated site-specific recombination. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[142] H. Albert,et al. Site-specific integration of DNA into wild-type and mutant lox sites placed in the plant genome. , 1995, The Plant journal : for cell and molecular biology.
[143] B. Kwabi-Addo,et al. A site–directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination , 1995, Nature Genetics.
[144] P. Sadowski. The Flp Recombinase of th 2-μm Plasmid of Saccharomyces cerevisiae , 1995 .
[145] K. Rajewsky,et al. Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies , 1994, Current Biology.
[146] T. Schlake,et al. Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci. , 1994, Biochemistry.
[147] K. Rajewsky,et al. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. , 1994, Science.
[148] R. Jaenisch,et al. Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[149] H. Nakano,et al. Targeted disruption of the CD3 eta locus causes high lethality in mice: modulation of Oct‐1 transcription on the opposite strand. , 1994, The EMBO journal.
[150] A. Schnieke,et al. Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice , 1994, Molecular and cellular biology.
[151] E. Reinherz,et al. CD3 zeta/eta/theta locus is colinear with and transcribed antisense to the gene encoding the transcription factor Oct-1. , 1993, Journal of immunology.
[152] J. Roder,et al. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[153] T. Doetschman,et al. Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy , 1993, Molecular and cellular biology.
[154] K. Rajewsky,et al. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting , 1993, Cell.
[155] T. Ratcliffe. Bac to the future , 1993 .
[156] G. Rubin,et al. Analysis of genetic mosaics in developing and adult Drosophila tissues. , 1993, Development.
[157] C. Cepko,et al. Lineage analysis using retrovirus vectors. , 1993, Methods in enzymology.
[158] D. Sherratt,et al. Catalysis by site-specific recombinases. , 1992, Trends in genetics : TIG.
[159] B. Birren,et al. Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[160] J. Marth,et al. Tissue- and site-specific DNA recombination in transgenic mice. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[161] B. Mosinger,et al. Targeted oncogene activation by site-specific recombination in transgenic mice. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[162] M. Gossen,et al. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[163] C. Cepko,et al. Widespread dispersion of neuronal clones across functional regions of the cerebral cortex. , 1992, Science.
[164] C. Cepko,et al. A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[165] N. Perrimon,et al. Use of a yeast site-specific recombinase to generate embryonic mosaics in Drosophila. , 1992, Developmental genetics.
[166] R. Pedersen,et al. Clonal analysis of cell fate during gastrulation and early neurulation in the mouse. , 1992, Ciba Foundation symposium.
[167] Yamamura Ken-ichi,et al. Efficient selection for high-expression transfectants with a novel eukaryotic vector , 1991 .
[168] H. Niwa,et al. Efficient selection for high-expression transfectants with a novel eukaryotic vector. , 1991, Gene.
[169] A. Amin,et al. Synapsis, strand scission, and strand exchange induced by the FLP recombinase: analysis with half-FRT sites , 1991, Molecular and cellular biology.
[170] R. Wetts,et al. Microinjection of fluorescent tracers to study neural cell lineages. , 1991, Development (Cambridge, England). Supplement.
[171] G. Wahl,et al. Recombinase-mediated gene activation and site-specific integration in mammalian cells. , 1991, Science.
[172] J. Rossant,et al. Embryonic stem cells alone are able to support fetal development in the mouse. , 1990, Development.
[173] Andrew P. McMahon,et al. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain , 1990, Cell.
[174] Mario R. Capecchi,et al. Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development , 1990, Nature.
[175] C. Cepko,et al. Lineage-independent determination of cell type in the embryonic mouse retina , 1990, Neuron.
[176] J. Sanes,et al. Neurons and glia arise from a common progenitor in chicken optic tectum: demonstration with two retroviruses and cell type-specific antibodies. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[177] S. Lindquist,et al. The FLP recombinase of yeast catalyzes site-specific recombination in the drosophila genome , 1989, Cell.
[178] B. Koller,et al. Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[179] A. Joyner,et al. Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes. , 1989, Science.
[180] I. Maxwell,et al. A DNA cassette containing a trimerized SV40 polyadenylation signal which efficiently blocks spurious plasmid-initiated transcription. , 1989, BioTechniques.
[181] N. Henderson,et al. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[182] M. Cox,et al. DNA recognition by the FLP recombinase of the yeast 2 mu plasmid. A mutational analysis of the FLP binding site. , 1988, Journal of molecular biology.
[183] M. Capecchi,et al. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells , 1987, Cell.
[184] Constance L. Cepko,et al. A common progenitor for neurons and glia persists in rat retina late in development , 1987, Nature.
[185] A. McMahon,et al. Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo , 1987, Cell.
[186] A. Bradley,et al. A potential animal model for Lesch–Nyhan syndrome through introduction of HPRT mutations into mice , 1987, Nature.
[187] R. Beddington,et al. The formation of mesodermal tissues in the mouse embryo during gastrulation and early organogenesis. , 1987, Development.
[188] T. Doetschman,et al. Transgenesis by means of blastocyst-derived embryonic stem cell lines. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[189] M. Capecchi,et al. Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene , 1986, Nature.
[190] A. Bradley,et al. Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector , 1986, Nature.
[191] J. Broach,et al. Identification of the crossover site during FLP-mediated recombination in the Saccharomyces cerevisiae plasmid 2 microns circle , 1986, Molecular and Cellular Biology.
[192] M. Cox,et al. Directionality in FLP protein-promoted site-specific recombination is mediated by DNA-DNA pairing. , 1986, The Journal of biological chemistry.
[193] R. Hoess,et al. The role of the loxP spacer region in P1 site-specific recombination. , 1986, Nucleic acids research.
[194] R. Kucherlapati,et al. Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination , 1985, Nature.
[195] S. Elledge,et al. Phasmid vectors for identification of genes by complementation of Escherichia coli mutants , 1985, Journal of bacteriology.
[196] S. Elledge,et al. Site-directed insertion and deletion mutagenesis with cloned fragments in Escherichia coli , 1985, Journal of bacteriology.
[197] R. Hoess,et al. Formation of small circular DNA molecules via an in vitro site-specific recombination system. , 1985, Gene.
[198] A. Bradley,et al. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines , 1984, Nature.
[199] R. Hoess,et al. P1 site-specific recombination: nucleotide sequence of the recombining sites. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[200] G. Martin,et al. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[201] M. Kaufman,et al. Establishment in culture of pluripotential cells from mouse embryos , 1981, Nature.
[202] R. Keller,et al. Vital dye mapping of the gastrula and neurula of Xenopus laevis: I. Prospective areas and morphogenetic movements of the superficial layer , 1976 .
[203] R. Keller,et al. Vital Dye Mapping of the Gastrula and Neurula of Xenopus Laevis , 1975 .
[204] A. Clark. Recombination deficient mutants of E. coli and other bacteria. , 1973, Annual review of genetics.
[205] C. W. Metz. Chromosome studies on the Diptera. II. The paired association of chromosomes in the Diptera, and its significance , 1916 .