Bridge over troubled waters: understanding the synthetic and biological identities of engineered

[1]  Andrzej S Pitek,et al.  Reversible versus irreversible binding of transferrin to polystyrene nanoparticles: soft and hard corona. , 2012, ACS nano.

[2]  A. Caminade,et al.  A Phosphorus-Based Dendrimer Targets Inflammation and Osteoclastogenesis in Experimental Arthritis , 2011, Science Translational Medicine.

[3]  A. Hursthouse,et al.  Working together: the combined application of a magnetic field and penetratin for the delivery of magnetic nanoparticles to cells in 3D. , 2011, ACS nano.

[4]  R. Jain,et al.  Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner , 2012, Nature nanotechnology.

[5]  Mauro Ferrari,et al.  Nanomedicine--challenge and perspectives. , 2009, Angewandte Chemie.

[6]  Tim Liedl,et al.  Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles. , 2005, Nano letters.

[7]  Florence Gazeau,et al.  Nanomagnetic sensing of blood plasma protein interactions with iron oxide nanoparticles: impact on macrophage uptake. , 2012, ACS nano.

[8]  Kanlaya Prapainop,et al.  A chemical approach for cell-specific targeting of nanomaterials: small-molecule-initiated misfolding of nanoparticle corona proteins. , 2012, Journal of the American Chemical Society.

[9]  Minnamari Vippola,et al.  Proteomic characterization of engineered nanomaterial-protein interactions in relation to surface reactivity. , 2011, ACS nano.

[10]  R Damoiseaux,et al.  No time to lose--high throughput screening to assess nanomaterial safety. , 2011, Nanoscale.

[11]  R. Stafford,et al.  Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[12]  Istvan Toth,et al.  Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation. , 2011, Nature nanotechnology.

[13]  Ji-Ho Park,et al.  Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance. , 2009, Biomaterials.

[14]  Nastassja A. Lewinski,et al.  Cytotoxicity of nanoparticles. , 2008, Small.

[15]  Rodney F. Minchin,et al.  Plasma protein binding of positively and negatively charged polymer-coated gold nanoparticles elicits different biological responses , 2012, Nanotoxicology.

[16]  Peter Wick,et al.  The adsorption of biomolecules to multi-walled carbon nanotubes is influenced by both pulmonary surfactant lipids and surface chemistry , 2010, Journal of nanobiotechnology.

[17]  P. Hunziker,et al.  Designing switchable nanosystems for medical application. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[18]  Mark B. Carter,et al.  The Targeted Delivery of Multicomponent Cargos to Cancer Cells via Nanoporous Particle-Supported Lipid Bilayers , 2011, Nature materials.

[19]  G. Oberdörster,et al.  Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology , 2010, Journal of internal medicine.

[20]  Ji-Xin Cheng,et al.  Label-free imaging of semiconducting and metallic carbon nanotubes in cells and mice using transient absorption microscopy. , 2011, Nature nanotechnology.

[21]  Bengt Fadeel,et al.  Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress. , 2012, Toxicology and applied pharmacology.

[22]  Karthikeyan Subramani,et al.  Magnetic resonance imaging tracking of stem cells in vivo using iron oxide nanoparticles as a tool for the advancement of clinical regenerative medicine. , 2011, Chemical reviews.

[23]  Warren C W Chan,et al.  Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. , 2007, Nano letters.

[24]  J. West,et al.  Correlating nanoscale titania structure with toxicity: a cytotoxicity and inflammatory response study with human dermal fibroblasts and human lung epithelial cells. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.

[25]  Heidi Goenaga-Infante,et al.  Dynamic monitoring of metal oxide nanoparticle toxicity by label free impedance sensing. , 2012, Chemical research in toxicology.

[26]  S. Toyokuni,et al.  Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis , 2011, Proceedings of the National Academy of Sciences.

[27]  Yasuo Yoshioka,et al.  Silica and titanium dioxide nanoparticles cause pregnancy complications in mice. , 2011, Nature nanotechnology.

[28]  S Moein Moghimi,et al.  Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere-serum interface: implications for stealth nanoparticle engineering. , 2010, ACS nano.

[29]  Stephen F Badylak,et al.  RETRACTED: Engineered whole organs and complex tissues , 2012, The Lancet.

[30]  S. Radford,et al.  Nucleation of protein fibrillation by nanoparticles , 2007, Proceedings of the National Academy of Sciences.

[31]  Lorenz M Mayr,et al.  Novel trends in high-throughput screening. , 2009, Current opinion in pharmacology.

[32]  Maurizio Prato,et al.  Carbon-nanotube shape and individualization critical for renal excretion. , 2008, Small.

[33]  Sanjay Mathur,et al.  Mapping the surface adsorption forces of nanomaterials in biological systems. , 2011, ACS nano.

[34]  Ruth Duncan,et al.  Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation , 2004, Nature Biotechnology.

[35]  Ronnie H. Fang,et al.  Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform , 2011, Proceedings of the National Academy of Sciences.

[36]  Navid B. Saleh,et al.  Does shape matter? Bioeffects of gold nanomaterials in a human skin cell model. , 2012, Langmuir : the ACS journal of surfaces and colloids.

[37]  Wolfgang J Parak,et al.  NIR-light triggered delivery of macromolecules into the cytosol. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[38]  Alison Elder,et al.  Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future. , 2010, ACS nano.

[39]  Saba Tm,et al.  Kupffer cell phagocytosis and metabolism of a variety of particles as a function of opsonization. , 1965 .

[40]  Neetu Singh,et al.  Nanoparticles that communicate in vivo to amplify tumour targeting. , 2011, Nature materials.

[41]  Bengt Fadeel,et al.  Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications. , 2010, Advanced drug delivery reviews.

[42]  Brahim Lounis,et al.  Direct investigation of intracellular presence of gold nanoparticles via photothermal heterodyne imaging. , 2011, ACS nano.

[43]  Aravind Subramanian,et al.  Perturbational profiling of nanomaterial biologic activity , 2008, Proceedings of the National Academy of Sciences.

[44]  James Chen Yong Kah,et al.  Exploiting the protein corona around gold nanorods for loading and triggered release. , 2012, ACS nano.

[45]  Yuri Volkov,et al.  High-content screening as a universal tool for fingerprinting of cytotoxicity of nanoparticles. , 2008, ACS nano.

[46]  M. Uesaka,et al.  Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. , 2011, Nature nanotechnology.

[47]  D. Ingber,et al.  Reconstituting Organ-Level Lung Functions on a Chip , 2010, Science.

[48]  Jean-Luc Coll,et al.  Physico-chemical parameters that govern nanoparticles fate also dictate rules for their molecular evolution. , 2012, Advanced drug delivery reviews.

[49]  Francesco Stellacci,et al.  Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles. , 2008, Nature materials.

[50]  Jim E Riviere,et al.  An index for characterization of nanomaterials in biological systems. , 2010, Nature nanotechnology.

[51]  Rebecca Robinson,et al.  Intravenous Hemostat: Nanotechnology to Halt Bleeding , 2009, Science Translational Medicine.

[52]  C. Alexiou,et al.  Locoregional cancer treatment with magnetic drug targeting. , 2000, Cancer research.

[53]  R. Duncan,et al.  Nanomedicine(s) under the microscope. , 2011, Molecular pharmaceutics.

[54]  T. Xia,et al.  Toxic Potential of Materials at the Nanolevel , 2006, Science.

[55]  N. D. Groodt,et al.  Alterations in the Ultrastructure of the Blood–Air Barrier in the Mouse Lung after Inhalation of Colloidal Gold Particles , 1958, Nature.

[56]  Bengt Fadeel,et al.  Impaired Clearance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice , 2012, PloS one.

[57]  Peter Wick,et al.  Nanotoxicology: an interdisciplinary challenge. , 2011, Angewandte Chemie.

[58]  Bengt Fadeel,et al.  Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos , 2012, Particle and Fibre Toxicology.

[59]  Teófilo Rojo,et al.  The challenge to relate the physicochemical properties of colloidal nanoparticles to their cytotoxicity. , 2013, Accounts of chemical research.

[60]  Robert Rallo,et al.  Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials. , 2011, ACS nano.

[61]  M. Malmsten,et al.  Nanomedicine: reshaping clinical practice , 2010, Journal of internal medicine.

[62]  A. Riedinger,et al.  A general synthetic approach for obtaining cationic and anionic inorganic nanoparticles via encapsulation in amphiphilic copolymers. , 2011, Small.

[63]  Anders Hult,et al.  Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers. , 2012, Biomaterials.

[64]  Mark E. Davis,et al.  Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles , 2010, Nature.

[65]  James L. McGrath,et al.  The influence of protein adsorption on nanoparticle association with cultured endothelial cells. , 2009, Biomaterials.

[66]  Kai Yang,et al.  Multimodal Imaging Guided Photothermal Therapy using Functionalized Graphene Nanosheets Anchored with Magnetic Nanoparticles , 2012, Advanced materials.

[67]  F. Collins,et al.  Transforming Environmental Health Protection , 2008, Science.

[68]  Albert Duschl,et al.  Hardening of the nanoparticle-protein corona in metal (Au, Ag) and oxide (Fe3O4, CoO, and CeO2) nanoparticles. , 2011, Small.

[69]  Marco Zanella,et al.  Biological applications of gold nanoparticles. , 2008, Chemical Society reviews.

[70]  Iseult Lynch,et al.  What the cell "sees" in bionanoscience. , 2010, Journal of the American Chemical Society.

[71]  M. Mortimer,et al.  High throughput kinetic Vibrio fischeri bioluminescence inhibition assay for study of toxic effects of nanoparticles. , 2008, Toxicology in vitro : an international journal published in association with BIBRA.

[72]  Moonjung Choi,et al.  Cellular uptake, cytotoxicity, and innate immune response of silica-titania hollow nanoparticles based on size and surface functionality. , 2010, ACS nano.

[73]  James H. Adair,et al.  Near-infrared emitting fluorophore-doped calcium phosphate nanoparticles for in vivo imaging of human breast cancer. , 2008, ACS nano.

[74]  Bengt Fadeel,et al.  Safety assessment of nanomaterials: implications for nanomedicine. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[75]  Warren C W Chan,et al.  Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment. , 2012, Chemical Society reviews.

[76]  Judith Klein-Seetharaman,et al.  Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation. , 2010, Nature nanotechnology.

[77]  Dai Fukumura,et al.  Multistage nanoparticle delivery system for deep penetration into tumor tissue , 2011, Proceedings of the National Academy of Sciences.

[78]  P. Ray Size and shape dependent second order nonlinear optical properties of nanomaterials and their application in biological and chemical sensing. , 2010, Chemical reviews.

[79]  Hak Soo Choi,et al.  Rapid translocation of nanoparticles from the lung airspaces to the body , 2010, Nature Biotechnology.

[80]  Sara Linse,et al.  Understanding the nanoparticle–protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles , 2007, Proceedings of the National Academy of Sciences.

[81]  David Y Lai,et al.  Toward toxicity testing of nanomaterials in the 21st century: a paradigm for moving forward. , 2012, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

[82]  G. Oberdörster,et al.  Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles , 2005, Environmental health perspectives.

[83]  R. Shah,et al.  Supramolecular design of self-assembling nanofibers for cartilage regeneration , 2010, Proceedings of the National Academy of Sciences of the United States of America.

[84]  S. K. Sundaram,et al.  Adsorbed proteins influence the biological activity and molecular targeting of nanomaterials. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.

[85]  Manuela Semmler-Behnke,et al.  Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration , 2011, Nanotoxicology.

[86]  R. Niessner,et al.  Multifunctional nanoparticles for dual imaging. , 2011, Analytical chemistry.

[87]  Staffan Strömblad,et al.  RETRACTED: Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: a proof-of-concept study , 2011, The Lancet.

[88]  D. Irvine,et al.  Bio-inspired, bioengineered and biomimetic drug delivery carriers , 2011, Nature Reviews Drug Discovery.

[89]  J. Lötvall,et al.  Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells , 2007, Nature Cell Biology.

[90]  Esther Parker,et al.  ELECTRON MICROSCOPY OF HELA CELLS AFTER THE INGESTION OF COLLOIDAL GOLD , 1957, The Journal of biophysical and biochemical cytology.

[91]  Stephen Mann,et al.  Nanoparticles can cause DNA damage across a cellular barrier. , 2009, Nature nanotechnology.

[92]  Forrest M Kievit,et al.  Cancer Nanotheranostics: Improving Imaging and Therapy by Targeted Delivery Across Biological Barriers , 2011, Advanced materials.

[93]  Lucía Gutiérrez,et al.  Biological applications of magnetic nanoparticles. , 2012, Chemical Society reviews.

[94]  Robert Langer,et al.  Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile , 2012, Science Translational Medicine.

[95]  Mandy B. Esch,et al.  Oral exposure to polystyrene nanoparticles affects iron absorption. , 2012, Nature nanotechnology.

[96]  P. Baron,et al.  Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. , 2008, American journal of physiology. Lung cellular and molecular physiology.

[97]  M. Pickard,et al.  The transfection of multipotent neural precursor/stem cell transplant populations with magnetic nanoparticles. , 2011, Biomaterials.

[98]  Davoud Ahmadvand,et al.  Material properties in complement activation. , 2011, Advanced drug delivery reviews.

[99]  Andrew Worth,et al.  Applying quantitative structure-activity relationship approaches to nanotoxicology: current status and future potential. , 2013, Toxicology.

[100]  M. Prato,et al.  Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[101]  Jim E Riviere,et al.  Pharmacokinetics of nanomaterials: an overview of carbon nanotubes, fullerenes and quantum dots. , 2009, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

[102]  Claus-Michael Lehr,et al.  The Interplay of Lung Surfactant Proteins and Lipids Assimilates the Macrophage Clearance of Nanoparticles , 2012, PloS one.

[103]  Patrick Couvreur,et al.  Translocation of poly(ethylene glycol-co-hexadecyl)cyanoacrylate nanoparticles into rat brain endothelial cells: role of apolipoproteins in receptor-mediated endocytosis. , 2007, Biomacromolecules.

[104]  Jerzy Leszczynski,et al.  Using nano-QSAR to predict the cytotoxicity of metal oxide nanoparticles. , 2011, Nature nanotechnology.

[105]  Li Tang,et al.  Synthesis and biological response of size-specific, monodisperse drug-silica nanoconjugates. , 2012, ACS nano.

[106]  Henrike Caysa,et al.  Tumor accumulation of NIR fluorescent PEG-PLA nanoparticles: impact of particle size and human xenograft tumor model. , 2011, ACS nano.

[107]  S M Moghimi,et al.  Factors controlling nanoparticle pharmacokinetics: an integrated analysis and perspective. , 2012, Annual review of pharmacology and toxicology.

[108]  Craig A. Poland,et al.  Zeta potential and solubility to toxic ions as mechanisms of lung inflammation caused by metal/metal oxide nanoparticles. , 2012, Toxicological sciences : an official journal of the Society of Toxicology.

[109]  Samuel I Stupp,et al.  Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair , 2011, Proceedings of the National Academy of Sciences.

[110]  Kenneth A. Dawson,et al.  Effects of the presence or absence of a protein corona on silica nanoparticle uptake and impact on cells. , 2012, ACS nano.

[111]  Wendelin J Stark,et al.  Nanoparticles in biological systems. , 2011, Angewandte Chemie.

[112]  Stefan Tenzer,et al.  Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomic analysis. , 2011, ACS nano.

[113]  Pratim Biswas,et al.  Assessing the relevance of in vitro studies in nanotoxicology by examining correlations between in vitro and in vivo data. , 2012, Toxicology.

[114]  Brahim Lounis,et al.  Cathepsin L digestion of nanobioconjugates upon endocytosis. , 2009, ACS nano.

[115]  Rui Hu,et al.  A pilot study in non-human primates shows no adverse response to intravenous injection of quantum dots. , 2012, Nature nanotechnology.

[116]  Zhuang Liu,et al.  Carbon nanotubes as photoacoustic molecular imaging agents in living mice. , 2008, Nature nanotechnology.

[117]  Li Wei,et al.  Sharper and faster "nano darts" kill more bacteria: a study of antibacterial activity of individually dispersed pristine single-walled carbon nanotube. , 2009, ACS nano.

[118]  Thomas Hartung,et al.  Alternative in vitro assays in nanomaterial toxicology. , 2011, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

[119]  Judith Klein-Seetharaman,et al.  Adsorption of surfactant lipids by single-walled carbon nanotubes in mouse lung upon pharyngeal aspiration. , 2012, ACS nano.

[120]  R. Zhou,et al.  Binding of blood proteins to carbon nanotubes reduces cytotoxicity , 2011, Proceedings of the National Academy of Sciences.

[121]  Iseult Lynch,et al.  The evolution of the protein corona around nanoparticles: a test study. , 2011, ACS nano.

[122]  Kenneth A. Dawson,et al.  Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts , 2008, Proceedings of the National Academy of Sciences.

[123]  Bengt Fadeel,et al.  Nanotoxicology: no small matter. , 2010, Nanoscale.

[124]  T. Mihaljevic,et al.  Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping , 2004, Nature Biotechnology.

[125]  Arezou A Ghazani,et al.  Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. , 2006, Nano letters.

[126]  Iseult Lynch,et al.  Designing the nanoparticle-biomolecule interface for "targeting and therapeutic delivery". , 2012, Journal of controlled release : official journal of the Controlled Release Society.