Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification.
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Jennifer C. Jones | G. Reifenberger | H. Schlüter | U. Schüller | M. Westphal | K. Pantel | C. Maire | M. Glatzel | K. Lamszus | R. Reimer | K. Kaulich | J. Welsh | F. Ricklefs | S. Joosse | A. Görgens | András G. Miklósi | D. Heiland | J. Felce | M. Fuh | Krystian D. Fita | Ines Stevic | Tammo Ricklefs | L. Dührsen | T. Sauvigny | M. Caselli | Valerio Pereno | Thomas Sauvigny
[1] K. Aldape,et al. Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes , 2020, Nature Medicine.
[2] N. Rosenfeld,et al. ctDNA monitoring using patient-specific sequencing and integration of variant reads , 2020, Science Translational Medicine.
[3] M. Westphal,et al. FASN Is a Biomarker Enriched in Malignant Glioma-Derived Extracellular Vesicles , 2020, International journal of molecular sciences.
[4] Valentina R Minciacchi,et al. Large and small extracellular vesicles released by glioma cells in vitro and in vivo , 2019, Journal of extracellular vesicles.
[5] L. Laurent,et al. Mechanisms of nuclear content loading to exosomes , 2019, Science Advances.
[6] J. Lötvall,et al. DNA analysis of low- and high-density fractions defines heterogeneous subpopulations of small extracellular vesicles based on their DNA cargo and topology , 2019, Journal of extracellular vesicles.
[7] F. Pearl,et al. Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping , 2019, Communications Biology.
[8] Dylan T Burnette,et al. Reassessment of Exosome Composition , 2019, Cell.
[9] X. Breakefield,et al. Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours , 2019, Journal of extracellular vesicles.
[10] P. Sundgren,et al. Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma , 2019, Clinical Cancer Research.
[11] R. Nieuwland,et al. Quality of extracellular vesicle images by transmission electron microscopy is operator and protocol dependent , 2019, Journal of extracellular vesicles.
[12] C. Brennan,et al. Tracking Tumor Evolution in Glioma through Liquid Biopsies of Cerebrospinal Fluid , 2018, Nature.
[13] Hakho Lee,et al. Characterization of single microvesicles in plasma from glioblastoma patients. , 2018, Neuro-oncology.
[14] F. DiMeco,et al. Clinical Significance of Extracellular Vesicles in Plasma from Glioblastoma Patients , 2018, Clinical Cancer Research.
[15] Valentina R Minciacchi,et al. Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma , 2018, Journal of extracellular vesicles.
[16] Martin Sill,et al. Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience , 2018, Acta Neuropathologica.
[17] Fatemeh Vafaee,et al. Deep sequencing of circulating exosomal microRNA allows non-invasive glioblastoma diagnosis , 2018, bioRxiv.
[18] N. Grabe,et al. Identification of CRKII, CFL1, CNTN1, NME2, and TKT as Novel and Frequent T-Cell Targets in Human IDH-Mutant Glioma , 2018, Clinical Cancer Research.
[19] Till Acker,et al. DNA methylation-based classification of central nervous system tumours , 2018, Nature.
[20] Hakho Lee,et al. Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles , 2018, Science Advances.
[21] Hakho Lee,et al. Multiplexed Profiling of Single Extracellular Vesicles. , 2018, ACS nano.
[22] C. Bettegowda,et al. Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients , 2017, Neuro-oncology.
[23] K. Nagao,et al. Exosomes maintain cellular homeostasis by excreting harmful DNA from cells , 2017, Nature Communications.
[24] M. Alonso,et al. DNA sequences within glioma-derived extracellular vesicles can cross the intact blood-brain barrier and be detected in peripheral blood of patients , 2016, Oncotarget.
[25] Joshua M. Weiss,et al. Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis. , 2016, Cancer cell.
[26] R. Christopherson,et al. Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease , 2016, Journal of Neuro-Oncology.
[27] K. Cornils,et al. Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles , 2016, PloS one.
[28] Mauro Delorenzi,et al. Sensitivity Analysis of the MGMT-STP27 Model and Impact of Genetic and Epigenetic Context to Predict the MGMT Methylation Status in Gliomas and Other Tumors. , 2016, The Journal of molecular diagnostics : JMD.
[29] J. Ptak,et al. Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord , 2015, Proceedings of the National Academy of Sciences.
[30] I. Nakano,et al. miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients , 2015, Journal of Neuro-Oncology.
[31] L. Montermini,et al. Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells. , 2014, Biochemical and biophysical research communications.
[32] Olivier Elemento,et al. Double-stranded DNA in exosomes: a novel biomarker in cancer detection , 2014, Cell Research.
[33] M. Choti,et al. Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies , 2014, Science Translational Medicine.
[34] Amaia Agirre,et al. A small noncoding RNA signature found in exosomes of GBM patient serum as a diagnostic tool. , 2014, Neuro-oncology.
[35] Lynda Chin,et al. Identification of Double-stranded Genomic DNA Spanning All Chromosomes with Mutated KRAS and p53 DNA in the Serum Exosomes of Patients with Pancreatic Cancer* , 2014, The Journal of Biological Chemistry.
[36] L. Liau,et al. BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles , 2013, Molecular therapy. Nucleic acids.
[37] M. Westphal,et al. Glioblastoma Stem–like Cell Lines with Either Maintenance or Loss of High-Level EGFR Amplification, Generated via Modulation of Ligand Concentration , 2012, Clinical Cancer Research.
[38] S. Pomeroy,et al. Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences. , 2011, Nature communications.
[39] D. Bigner,et al. Proteomic and immunologic analyses of brain tumor exosomes , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[40] Johan Skog,et al. Glioblastoma microvesicles transport RNA and protein that promote tumor growth and provide diagnostic biomarkers , 2008, Nature Cell Biology.
[41] M. Westphal,et al. Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria , 2008, Oncogene.