Quantitative Analysis of the Openness of the Major Temporal Arcade in Retinal Fundus Images of Retinopathy of Prematurity

Monitoring the openness of the major temporal arcade (MTA) and how it changes in the presence of various forms of retinopathy, such as retinopathy of prematurity (ROP), could assist in timely detection and effective treatment. We present image processing techniques, including Gabor filters and a form of the generalized Hough transform, for the detection and modeling of the MTA via a graphical user interface (GUI). An arcade angle was also obtained via the GUI. An area under the receiver operating characteristic curve of A z = 0.75 was obtained using the results of single- and dual-parabolic modeling in the discrimination of Stage 0 ROP from Stage 3 ROP; A z = 0.71 was obtained in screening for ROP (Stage 0 versus Stages 1, 2, and 3). The arcade angle provided similar results in terms of A z values.

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