Silencing STATs: lessons from paramyxovirus interferon evasion.

[1]  C. Horvath,et al.  Identification of the Nuclear Export Signal and STAT-Binding Domains of the Nipah Virus V Protein Reveals Mechanisms Underlying Interferon Evasion , 2004, Journal of Virology.

[2]  R. Deshaies,et al.  Human De-Etiolated-1 Regulates c-Jun by Assembling a CUL4A Ubiquitin Ligase , 2004, Science.

[3]  Hua Yu,et al.  The STATs of cancer — new molecular targets come of age , 2004, Nature Reviews Cancer.

[4]  C. Horvath,et al.  Erratum: Hendra Virus V Protein Inhibits Interferon Signaling by Preventing STAT1 and STAT2 Nuclear Accumulation (Journal of Virology (2003) 77:21 (11842-11845)) , 2003 .

[5]  C. Horvath,et al.  Hendra Virus V Protein Inhibits Interferon Signaling by Preventing STAT1 and STAT2 Nuclear Accumulation , 2003, Journal of Virology.

[6]  S. Krishnamurthy,et al.  Newcastle Disease Virus V Protein Is Associated with Viral Pathogenesis and Functions as an Alpha Interferon Antagonist , 2003, Journal of Virology.

[7]  C. Horvath,et al.  STAT Protein Interference and Suppression of Cytokine Signal Transduction by Measles Virus V Protein , 2003, Journal of Virology.

[8]  R. Levy,et al.  The human type I interferon receptor: NMR structure reveals the molecular basis of ligand binding. , 2003, Structure.

[9]  C. Horvath,et al.  STAT3 Ubiquitylation and Degradation by Mumps Virus Suppress Cytokine and Oncogene Signaling , 2003, Journal of Virology.

[10]  H. Saito,et al.  Measles virus suppresses interferon-α signaling pathway: suppression of Jak1 phosphorylation and association of viral accessory proteins, C and V, with interferon-α receptor complex , 2003 .

[11]  Nicole M. Bouvier,et al.  Newcastle Disease Virus (NDV)-Based Assay Demonstrates Interferon-Antagonist Activity for the NDV V Protein and the Nipah Virus V, W, and C Proteins , 2003, Journal of Virology.

[12]  C. Horvath,et al.  Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components. , 2002, Virology.

[13]  T. Kubota,et al.  C-Terminal Region of STAT-1α Is Not Necessary for Its Ubiquitination and Degradation Caused by Mumps Virus V Protein , 2002, Journal of Virology.

[14]  S. Goodbourn,et al.  The p127 Subunit (DDB1) of the UV-DNA Damage Repair Binding Protein Is Essential for the Targeted Degradation of STAT1 by the V Protein of the Paramyxovirus Simian Virus 5 , 2002, Journal of Virology.

[15]  C. Horvath,et al.  Nipah Virus V Protein Evades Alpha and Gamma Interferons by Preventing STAT1 and STAT2 Activation and Nuclear Accumulation , 2002, Journal of Virology.

[16]  R. Lamb,et al.  The V proteins of simian virus 5 and other paramyxoviruses inhibit induction of interferon-beta. , 2002, Virology.

[17]  R. Lamb,et al.  Recovery of paramyxovirus simian virus 5 with a V protein lacking the conserved cysteine-rich domain: the multifunctional V protein blocks both interferon-beta induction and interferon signaling. , 2002, Virology.

[18]  G. Parks,et al.  Naturally Occurring Substitutions in the P/V Gene Convert the Noncytopathic Paramyxovirus Simian Virus 5 into a Virus That Induces Alpha/Beta Interferon Synthesis and Cell Death , 2002, Journal of Virology.

[19]  J. Darnell.  Transcription factors as targets for cancer therapy , 2002, Nature Reviews Cancer.

[20]  J. Turkson,et al.  STAT3 Activation by Type I Interferons Is Dependent on Specific Tyrosines Located in the Cytoplasmic Domain of Interferon Receptor Chain 2c , 2002, The Journal of Biological Chemistry.

[21]  V. ter meulen,et al.  Hemagglutinin Protein of Wild-Type Measles Virus Activates Toll-Like Receptor 2 Signaling , 2002, Journal of Virology.

[22]  D. Garcin,et al.  The carboxyl segment of the mumps virus V protein associates with Stat proteins in vitro via a tryptophan-rich motif. , 2002, Virology.

[23]  J. ten Hoeve,et al.  Identification of a Nuclear Stat1 Protein Tyrosine Phosphatase , 2002, Molecular and Cellular Biology.

[24]  C. Horvath,et al.  STAT2 Acts as a Host Range Determinant for Species-Specific Paramyxovirus Interferon Antagonism and Simian Virus 5 Replication , 2002, Journal of Virology.

[25]  D. Aaronson,et al.  A Road Map for Those Who Don't Know JAK-STAT , 2002, Science.

[26]  C. Horvath,et al.  Selective STAT Protein Degradation Induced by Paramyxoviruses Requires both STAT1 and STAT2 but Is Independent of Alpha/Beta Interferon Signal Transduction , 2002, Journal of Virology.

[27]  C. Schindler,et al.  Series Introduction: JAK-STAT signaling in human disease , 2002 .

[28]  J. Bell,et al.  Oncolytic viruses: programmable tumour hunters. , 2002, Current gene therapy.

[29]  D. Levy,et al.  What does Stat3 do? , 2002, The Journal of clinical investigation.

[30]  R. Jove,et al.  Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

[31]  I. Lödige,et al.  Constitutive and IFN‐γ‐induced nuclear import of STAT1 proceed through independent pathways , 2002 .

[32]  K. Takeuchi,et al.  Paramyxovirus Accessory Proteins as Interferon Antagonists , 2001, Microbiology and immunology.

[33]  T. Hyypiä,et al.  Measles Virus Activates NF-κB and STAT Transcription Factors and Production of IFN-α/β and IL-6 in the Human Lung Epithelial Cell Line A549 , 2001 .

[34]  P. Raychaudhuri,et al.  The Xeroderma Pigmentosum Group E Gene Product DDB2 Is a Specific Target of Cullin 4A in Mammalian Cells , 2001, Molecular and Cellular Biology.

[35]  R. Lamb,et al.  The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2. , 2001, Virology.

[36]  T. Kubota,et al.  C terminal CYS-RICH region of mumps virus structural V protein correlates with block of interferon alpha and gamma signal transduction pathway through decrease of STAT 1-alpha. , 2001, Biochemical and biophysical research communications.

[37]  W. Bellini,et al.  Molecular biology of Hendra and Nipah viruses. , 2001, Microbes and infection.

[38]  R. Lamb,et al.  Single Amino Acid Substitution in the V Protein of Simian Virus 5 Differentiates Its Ability To Block Interferon Signaling in Human and Murine Cells , 2001, Journal of Virology.

[39]  C. Horvath,et al.  STAT proteins and transcriptional responses to extracellular signals. , 2000, Trends in biochemical sciences.

[40]  S. Goodbourn,et al.  Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures. , 2000, The Journal of general virology.

[41]  R. Lamb,et al.  The Paramyxovirus Simian Virus 5 V Protein Slows Progression of the Cell Cycle , 2000, Journal of Virology.

[42]  G. Stark,et al.  Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2 , 2000, Nature Immunology.

[43]  H. Field,et al.  Nipah virus: a recently emergent deadly paramyxovirus. , 2000, Science.

[44]  S. Goodbourn,et al.  Paramyxoviridae use distinct virus-specific mechanisms to circumvent the interferon response. , 2000, Virology.

[45]  P. Raychaudhuri,et al.  Cullin 4A Associates with the UV-damaged DNA-binding Protein DDB* , 1999, The Journal of Biological Chemistry.

[46]  S. Goodbourn,et al.  The V Protein of Simian Virus 5 Inhibits Interferon Signalling by Targeting STAT1 for Proteasome-Mediated Degradation , 1999, Journal of Virology.

[47]  R. Ransohoff,et al.  Catalytically Active TYK2 Is Essential for Interferon-β-mediated Phosphorylation of STAT3 and Interferon-α Receptor-1 (IFNAR-1) but Not for Activation of Phosphoinositol 3-Kinase* , 1999, The Journal of Biological Chemistry.

[48]  C. Schindler,et al.  Murine Stat2 is uncharacteristically divergent. , 1999, Nucleic acids research.

[49]  D. Levy,et al.  Stat Protein Transactivation Domains Recruit p300/CBP through Widely Divergent Sequences* , 1999, The Journal of Biological Chemistry.

[50]  J E Darnell,et al.  A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[51]  C. Miki,et al.  Serum interleukin‐6 level reflects the tumor proliferative activity in patients with colorectal carcinoma , 1999, Cancer.

[52]  S. Goodbourn,et al.  Sendai Virus and Simian Virus 5 Block Activation of Interferon-Responsive Genes: Importance for Virus Pathogenesis , 1999, Journal of Virology.

[53]  Leo Koenderman,et al.  Lineage‐specific activation of STAT3 by interferon‐γ in human neutrophils , 1999, Journal of leukocyte biology.

[54]  R. Lamb,et al.  The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding protein. , 1998, Virology.

[55]  J. Darnell,et al.  Crystal Structure of a Tyrosine Phosphorylated STAT-1 Dimer Bound to DNA , 1998, Cell.

[56]  L. Pfeffer,et al.  STAT3 complements defects in an interferon-resistant cell line: evidence for an essential role for STAT3 in interferon signaling and biological activities. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[57]  J. Darnell,et al.  Structure of the amino-terminal protein interaction domain of STAT-4. , 1998, Science.

[58]  R. Randall,et al.  Isolation of highly fusogenic variants of simian virus 5 from persistently infected cells that produce and respond to interferon , 1997, Journal of virology.

[59]  D. Levy,et al.  Regulation of Interferon-α Responsiveness by the Duration of Janus Kinase Activity* , 1997, The Journal of Biological Chemistry.

[60]  G. Stark,et al.  Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling , 1997, Molecular and cellular biology.

[61]  J. Darnell,et al.  The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase. , 1996, The EMBO journal.

[62]  R. Randall,et al.  NP:P and NP:V interactions of the paramyxovirus simian virus 5 examined using a novel protein:protein capture assay. , 1996, Virology.

[63]  Y. Ito,et al.  Interaction between nucleocapsid protein (NP) and phosphoprotein (P) of human parainfluenza virus type 2: one of the two NP binding sites on P is essential for granule formation. , 1996, The Journal of general virology.

[64]  Y. Ito,et al.  Binding of the V proteins to the nucleocapsid proteins of human parainfluenza type 2 virus , 1996, Medical Microbiology and Immunology.

[65]  S. Constantinescu,et al.  Direct Association of STAT3 with the IFNAR-1 Chain of the Human Type I Interferon Receptor (*) , 1996, The Journal of Biological Chemistry.

[66]  J. Darnell,et al.  The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active Stat1 protein , 1996, Journal of virology.

[67]  R. Randall,et al.  Inducible expression of the P, V, and NP genes of the paramyxovirus simian virus 5 in cell lines and an examination of NP-P and NP-V interactions , 1995, Journal of virology.

[68]  R. Lamb,et al.  The paramyxovirus SV5 V protein binds two atoms of zinc and is a structural component of virions. , 1995, Virology.

[69]  R. Randall,et al.  Evidence that the paramyxovirus simian virus 5 can establish quiescent infections by remaining inactive in cytoplasmic inclusion bodies. , 1994, The Journal of general virology.

[70]  J. Garcia,et al.  Cytoplasmic inclusions of respiratory syncytial virus-infected cells: formation of inclusion bodies in transfected cells that coexpress the nucleoprotein, the phosphoprotein, and the 22K protein. , 1993, Virology.

[71]  G. Stark,et al.  High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[72]  M. Yamamoto,et al.  Suicide process of renal cell carcinoma cells encountering mumps virus , 1991, FEBS letters.

[73]  Masahiro Yamamoto,et al.  Interleukin‐6 (IL‐6) functions as an in vitro autocrine growth factor in renal cell carcinomas , 1989, FEBS letters.

[74]  Sheila M. Thomas,et al.  Two mRNAs that differ by two nontemplated nucleotides encode the amino coterminal proteins P and V of the paramyxovirus SV5 , 1988, Cell.

[75]  J. Seyer,et al.  Localization and characterization of Sendai virus nonstructural C and C' proteins by antibodies against synthetic peptides. , 1986, Virus research.

[76]  B. Fleischer,et al.  Clonal analysis of HLA-restricted virus-specific cytotoxic T lymphocytes from cerebrospinal fluid in mumps meningitis. , 1983, Journal of immunology.

[77]  B. Fleischer,et al.  Mumps virus replication in human lymphoid cell lines and in peripheral blood lymphocytes: preference for T cells , 1982, Infection and immunity.

[78]  K. Yamanishi,et al.  Studies on the use of mumps virus for treatment of human cancer. , 1978, Biken journal.

[79]  T. Asada.  Treatment of human cancer with mumps virus , 1974, Cancer.

[80]  F. Čiampor,et al.  Localization of nucleocapsid associated polypeptides in measles virus-infected cells by immunogold labelling after resin embedding , 2005, Archives of Virology.

[81]  S. Lam.  Nipah virus--a potential agent of bioterrorism? , 2003, Antiviral research.

[82]  R. Deshaies.  SCF and Cullin/Ring H2-based ubiquitin ligases. , 1999, Annual review of cell and developmental biology.

[83]  T. Kubota,et al.  Poor induction of interferon-induced 2′,5′-oligoadenylate synthetase (2–5 AS) in cells persistently infected with mumps virus is caused by decrease of STAT-1α , 1998, Archives of Virology.

[84]  Stark Gr.  Genetic analysis of interferon and other mammalian signaling pathways. , 1997 .

[85]  R. Lamb,et al.  Orthomyxoviridae: The Viruses and Their Replication. , 1996 .

[86]  P. Liston,et al.  Measles virus V protein binds zinc. , 1994, Virology.