A photoacoustic imaging reconstruction method based on directional total variation with adaptive directivity

BackgroundIn photoacoustic tomography (PAT), total variation (TV) based iteration algorithm is reported to have a good performance in PAT image reconstruction. However, classical TV based algorithm fails to preserve the edges and texture details of the image because it is not sensitive to the direction of the image. Therefore, it is of great significance to develop a new PAT reconstruction algorithm to effectively solve the drawback of TV.MethodsIn this paper, a directional total variation with adaptive directivity (DDTV) model-based PAT image reconstruction algorithm, which weightedly sums the image gradients based on the spatially varying directivity pattern of the image is proposed to overcome the shortcomings of TV. The orientation field of the image is adaptively estimated through a gradient-based approach. The image gradients are weighted at every pixel based on both its anisotropic direction and another parameter, which evaluates the estimated orientation field reliability. An efficient algorithm is derived to solve the iteration problem associated with DDTV and possessing directivity of the image adaptively updated for each iteration step.Results and conclusionSeveral texture images with various directivity patterns are chosen as the phantoms for the numerical simulations. The 180-, 90- and 30-view circular scans are conducted. Results obtained show that the DDTV-based PAT reconstructed algorithm outperforms the filtered back-projection method (FBP) and TV algorithms in the quality of reconstructed images with the peak signal-to-noise rations (PSNR) exceeding those of TV and FBP by about 10 and 18 dB, respectively, for all cases. The Shepp–Logan phantom is studied with further discussion of multimode scanning, convergence speed, robustness and universality aspects. In-vitro experiments are performed for both the sparse-view circular scanning and linear scanning. The results further prove the effectiveness of the DDTV, which shows better results than that of the TV with sharper image edges and clearer texture details. Both numerical simulation and in vitro experiments confirm that the DDTV provides a significant quality improvement of PAT reconstructed images for various directivity patterns.

[1]  Lihong V. Wang,et al.  Photoacoustic imaging in biomedicine , 2006 .

[2]  Zhang,et al.  Sound field of thermoacoustic tomography based on a modified finite-difference time-domain method , 2009 .

[3]  Liang Xiao,et al.  Iterative Directional Total Variation Refinement for Compressive Sensing Image Reconstruction , 2013, IEEE Signal Processing Letters.

[4]  Bradley E. Treeby,et al.  Artifact Trapping During Time Reversal Photoacoustic Imaging for Acoustically Heterogeneous Media , 2010, IEEE Transactions on Medical Imaging.

[5]  R. Kruger,et al.  Photoacoustic ultrasound (PAUS)--reconstruction tomography. , 1995, Medical physics.

[6]  C.-C. Jay Kuo,et al.  Adaptive Directional Total-Variation Model for Latent Fingerprint Segmentation , 2013, IEEE Transactions on Information Forensics and Security.

[7]  Lihong V. Wang,et al.  Application of time reversal to thermoacoustic tomography , 2004, SPIE BiOS.

[8]  Yuanyuan Wang,et al.  High total variation-based method for sparse-view photoacoustic reconstruction , 2014 .

[9]  Emmanuel J. Candès,et al.  Robust uncertainty principles: exact signal reconstruction from highly incomplete frequency information , 2004, IEEE Transactions on Information Theory.

[10]  Lihong V. Wang,et al.  Noninvasive laser-induced photoacoustic tomography for structural and functional in vivo imaging of the brain , 2003, Nature Biotechnology.

[11]  Yi Zhang,et al.  Enhanced efficiency of the luminescent solar concentrator fabricated with an aqueous layer , 2014 .

[12]  Lihong V. Wang,et al.  Photoacoustic imaging of lacZ gene expression in vivo. , 2007, Journal of biomedical optics.

[13]  Lihong V. Wang,et al.  Time reversal and its application to tomography with diffracting sources. , 2004, Physical review letters.

[14]  Mark A. Anastasio,et al.  Full-Wave Iterative Image Reconstruction in Photoacoustic Tomography With Acoustically Inhomogeneous Media , 2013, IEEE Transactions on Medical Imaging.

[15]  Vasilis Ntziachristos,et al.  Acceleration of Optoacoustic Model-Based Reconstruction Using Angular Image Discretization , 2012, IEEE Transactions on Medical Imaging.

[16]  A. Hero,et al.  A Fast Spectral Method for Active 3D Shape Reconstruction , 2004 .

[17]  C.-C. Jay Kuo,et al.  Latent fingerprint detection and segmentation with a directional total variation model , 2012, 2012 19th IEEE International Conference on Image Processing.

[18]  Vasilis Ntziachristos,et al.  Efficient Framework for Model-Based Tomographic Image Reconstruction Using Wavelet Packets , 2012, IEEE Transactions on Medical Imaging.

[19]  Lihong V Wang,et al.  Photoacoustic tomography and sensing in biomedicine , 2009, Physics in medicine and biology.

[20]  Steve B. Jiang,et al.  Low-dose CT reconstruction via edge-preserving total variation regularization. , 2010, Physics in medicine and biology.

[21]  Emil Y. Sidky,et al.  Limited data image reconstruction in optoacoustic tomography by constrained total variation minimization , 2011, BiOS.

[22]  Jan Laufer,et al.  Quantitative spatially resolved measurement of tissue chromophore concentrations using photoacoustic spectroscopy: application to the measurement of blood oxygenation and haemoglobin concentration , 2007, Physics in medicine and biology.

[23]  Quing Zhu,et al.  Real-time photoacoustic tomography of cortical hemodynamics in small animals. , 2010, Journal of biomedical optics.

[24]  Lihong V. Wang,et al.  Tutorial on Photoacoustic Microscopy and Computed Tomography , 2008, IEEE Journal of Selected Topics in Quantum Electronics.

[25]  Da Xing,et al.  Imaging-guided high-efficient photoacoustic tumor therapy with targeting gold nanorods. , 2015, Nanomedicine : nanotechnology, biology, and medicine.

[26]  Minghua Xu,et al.  Pulsed-microwave-induced thermoacoustic tomography: filtered backprojection in a circular measurement configuration. , 2002, Medical physics.

[27]  B. Cox,et al.  Photoacoustic tomography in absorbing acoustic media using time reversal , 2010 .

[28]  Zhuang Liu,et al.  Carbon nanotubes as photoacoustic molecular imaging agents in living mice. , 2008, Nature nanotechnology.

[29]  Minghua Xu,et al.  Time-domain reconstruction for thermoacoustic tomography in a spherical geometry , 2002, IEEE Transactions on Medical Imaging.

[30]  Benjamin Berkels,et al.  Cartoon Extraction Based on Anisotropic Image Classification Vision , Modeling , and Visualization Proceedings , 2006 .

[31]  L. Rudin,et al.  Nonlinear total variation based noise removal algorithms , 1992 .

[32]  Chen Zhang,et al.  Total variation based gradient descent algorithm for sparse-view photoacoustic image reconstruction. , 2012, Ultrasonics.

[33]  En Zhu,et al.  A systematic method for fingerprint ridge orientation estimation and image segmentation , 2006, Pattern Recognit..

[34]  Tanja Tarvainen,et al.  Image reconstruction with uncertainty quantification in photoacoustic tomography. , 2016, The Journal of the Acoustical Society of America.

[35]  Ilker Bayram,et al.  Directional Total Variation , 2012, IEEE Signal Processing Letters.

[36]  Sihua Yang,et al.  Limited-view photoacoustic imaging based on linear-array detection and filtered mean-backprojection-iterative reconstruction , 2009 .

[37]  Anil K. Jain,et al.  Fingerprint Image Enhancement: Algorithm and Performance Evaluation , 1998, IEEE Trans. Pattern Anal. Mach. Intell..

[38]  Frédéric Lesage,et al.  The Application of Compressed Sensing for Photo-Acoustic Tomography , 2009, IEEE Transactions on Medical Imaging.

[39]  Stephen P. Boyd,et al.  Enhancing Sparsity by Reweighted ℓ1 Minimization , 2007, 0711.1612.

[40]  L. Kunyansky,et al.  Explicit inversion formulae for the spherical mean Radon transform , 2006, math/0609341.

[41]  Martin Frenz,et al.  Combined ultrasound and optoacoustic system for real-time high-contrast vascular imaging in vivo , 2005, IEEE Transactions on Medical Imaging.

[42]  S. Jacques,et al.  Iterative reconstruction algorithm for optoacoustic imaging. , 2002, The Journal of the Acoustical Society of America.

[43]  M. Nikolova An Algorithm for Total Variation Minimization and Applications , 2004 .

[44]  R A Kruger,et al.  Thermoacoustic computed tomography--technical considerations. , 1999, Medical physics.

[45]  Steve B. Jiang,et al.  Low-dose CT reconstruction via edge-preserving total variation regularization , 2010, Physics in medicine and biology.

[46]  S. Osher,et al.  Decomposition of images by the anisotropic Rudin‐Osher‐Fatemi model , 2004 .

[47]  Chi Zhang,et al.  Fast and Robust Deconvolution-Based Image Reconstruction for Photoacoustic Tomography in Circular Geometry: Experimental Validation , 2010, IEEE Photonics Journal.

[48]  Chi Zhang,et al.  Deconvolution reconstruction of full-view and limited-view photoacoustic tomography: a simulation study. , 2008, Journal of the Optical Society of America. A, Optics, image science, and vision.

[49]  S. Frick,et al.  Compressed Sensing , 2014, Computer Vision, A Reference Guide.

[50]  Marta Betcke,et al.  Accelerated high-resolution photoacoustic tomography via compressed sensing , 2016, Physics in medicine and biology.