Phosphatidic acid and phospholipase D both stimulate phosphoinositide turnover in cultured human keratinocytes.

[1]  P. Corr,et al.  Phosphatidic acid stimulates inositol 1,4,5-trisphosphate production in adult cardiac myocytes. , 1993, Circulation research.

[2]  V. Kinzel,et al.  Proposed role of phosphatidic acid in the extracellular control of the transition from G2 phase to mitosis exerted by epidermal growth factor in A431 cells. , 1992, Cancer research.

[3]  K. Wirtz,et al.  Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase. , 1992, The Journal of biological chemistry.

[4]  R. Irvine.  Inositol lipids in cell signalling. , 1992 .

[5]  K. Jalink,et al.  Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin. , 1992, The Biochemical journal.

[6]  F. Marks,et al.  Activation of a keratinocyte phospholipase A2 by bradykinin and 4β-phorbol 12-myristate 13-acetate , 1991 .

[7]  J. Voorhees,et al.  Epidermal growth factor‐induced hydrolysis of phosphatidylcholine by phospholipase D and phospholipase C in human dermal fibroblasts , 1991, Journal of cellular physiology.

[8]  J. Voorhees,et al.  Bradykinin induces phosphoinositide turnover, 1,2-diglyceride formation, and growth in cultured adult human keratinocytes. , 1990, The Journal of investigative dermatology.

[9]  J. Voorhees,et al.  Increased phospholipase C-catalyzed hydrolysis of phosphatidylinositol-4,5-bisphosphate and 1,2-sn-diacylglycerol content in psoriatic involved compared to uninvolved and normal epidermis. , 1990, The Journal of investigative dermatology.

[10]  H. Abboud,et al.  Phosphatidic acid modulates DNA synthesis, phospholipase C, and platelet-derived growth factor mRNAs in cultured mesangial cells. Role of protein kinase C. , 1990, The Journal of biological chemistry.

[11]  K. Jalink,et al.  Lysophosphatidic acid, but not phosphatidic acid, is a potent Ca2(+)-mobilizing stimulus for fibroblasts. Evidence for an extracellular site of action. , 1990, The Journal of biological chemistry.

[12]  J. Voorhees,et al.  Differential activation of human skin cells by platelet activating factor: stimulation of phosphoinositide turnover and arachidonic acid mobilization in keratinocytes but not in fibroblasts. , 1989, Biochemical and biophysical research communications.

[13]  R. Sagi-Eisenberg.  GTP-binding proteins as possible targets for protein kinase C action. , 1989, Trends in biochemical sciences.

[14]  J. Voorhees,et al.  Agonist-induced hydrolysis of phosphoinositides and formation of 1,2-diacylglycerol in adult human keratinocytes. , 1989, The Journal of investigative dermatology.

[15]  James T. Elder,et al.  Increased phosphatidylinositol kinase activity in psoriatic epidermis. , 1989, The Journal of investigative dermatology.

[16]  M. Kroll,et al.  Second messenger function of phosphatidic acid in platelet activation , 1989, Journal of cellular physiology.

[17]  R. Egan,et al.  Regulation of phospholipase D in HL-60 granulocytes. Activation by phorbol esters, diglyceride, and calcium ionophore via protein kinase- independent mechanisms. , 1989, The Journal of biological chemistry.

[18]  C. Rock,et al.  Stimulation of phosphatidylinositol 4,5-bisphosphate phospholipase C activity by phosphatidic acid. , 1989, Archives of biochemistry and biophysics.

[19]  Y. Nozawa,et al.  Increased protein kinase C activity in fibroblast membranes from psoriatic patients. , 1988, The Journal of investigative dermatology.

[20]  D. Stacey,et al.  Cellular ras activity and phospholipid metabolism , 1988, Cell.

[21]  P. Blackmore,et al.  Phosphatidate accumulation in hormone-treated hepatocytes via a phospholipase D mechanism. , 1987, The Journal of biological chemistry.

[22]  J. Altin,et al.  Phosphatidic acid and arachidonic acid each interact synergistically with glucagon to stimulate Ca2+ influx in the perfused rat liver. , 1987, The Biochemical journal.

[23]  M. Ui,et al.  Possible involvement of a GTP-binding protein, the substrate of islet-activating protein, in receptor-mediated signaling responsible for cell proliferation. , 1987, The Journal of biological chemistry.

[24]  D. Siegmann,et al.  Stimulation of quiescent 3T3 cells by phosphatidic acid-containing liposomes. , 1987, Biochemical and biophysical research communications.

[25]  R. Farese,et al.  Insulin rapidly increases diacylglycerol by activating de novo phosphatidic acid synthesis. , 1987, Science.

[26]  M. Ui,et al.  Phosphatidic acid may stimulate membrane receptors mediating adenylate cyclase inhibition and phospholipid breakdown in 3T3 fibroblasts. , 1987, The Journal of biological chemistry.

[27]  J. Voorhees,et al.  Partial characterization of phospholipase C activity in normal, psoriatic uninvolved, and lesional epidermis. , 1987, The Journal of investigative dermatology.

[28]  J. Voorhees,et al.  Decreased protein kinase C activity in psoriatic versus normal epidermis. , 1987, The Journal of investigative dermatology.

[29]  I. Verlaan,et al.  Growth factor-like action of phosphatidic acid , 1986, Nature.

[30]  K. Longmuir,et al.  Phosphorylation, transbilayer movement, and facilitated intracellular transport of diacylglycerol are involved in the uptake of a fluorescent analog of phosphatidic acid by cultured fibroblasts. , 1985, The Journal of biological chemistry.

[31]  Michael J. Berridge,et al.  Inositol trisphosphate, a novel second messenger in cellular signal transduction , 1984, Nature.

[32]  S. Cockcroft.  Ca2+-dependent conversion of phosphatidylinositol to phosphatidate in neutrophils stimulated with fMet-Leu-Phe or ionophore A23187. , 1984, Biochimica et biophysica acta.

[33]  M. Berridge,et al.  Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides. , 1983, The Biochemical journal.

[34]  J. Williamson,et al.  Quantitation and early kinetics of inositol lipid changes induced by vasopressin in isolated and cultured hepatocytes. , 1983, The Journal of biological chemistry.

[35]  T. Deguchi,et al.  Phosphatidic acid mimicks the muscarinic action of acetylcholine in cultured bovine chromaffin cells , 1983 .

[36]  T. Takenawa,et al.  Increased formation of phosphatidic acid induced with vasopressin or Ca2+ ionophore A23187 in rat hepatocytes. , 1982, Biochemical pharmacology.

[37]  P. Cuatrecasas,et al.  The phosphatidylinositol cycle and the regulation of arachidonic acid production , 1981, Nature.

[38]  R. Harris,et al.  Phosphatidate as a molecular link between depolarization and neurotransmitter release in the brain. , 1981, Science.

[39]  G. Barritt,et al.  Evidence that phosphatidic acid stimulates the uptake of calcium by liver cells but not calcium release from mitochondria , 1981, FEBS letters.

[40]  T. Honeyman,et al.  Proposed mechanism of cholinergic action in smooth muscle , 1980, Nature.

[41]  Y Nishizuka,et al.  Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover. , 1980, The Journal of biological chemistry.

[42]  C. Tyson,et al.  Phospholipids as ionophores. , 1976, The Journal of biological chemistry.

[43]  K. Sadeghian,et al.  Inositol is the water-soluble product of acetylcholine-stimulated breakdown of phosphatidylinositol in mouse pancreas. , 1975, Biochemical and biophysical research communications.

[44]  R. Michell.  Inositol phospholipids and cell surface receptor function. , 1975, Biochimica et biophysica acta.