P2X7 receptors in cerebral ischemia

[1]  K. Fukunaga,et al.  P2X7 signaling promotes microsphere embolism-triggered microglia activation by maintaining elevation of Fas ligand , 2012, Journal of Neuroinflammation.

[2]  M. Mao,et al.  P2X7 receptor modulation of the viability of radial glial clone L2.3 cells during hypoxic-ischemic brain injury. , 2012, Molecular medicine reports.

[3]  B. Luo,et al.  Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus , 2012, Journal of Neuroinflammation.

[4]  A. Pérez-Samartín,et al.  P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia , 2012, Neurobiology of Disease.

[5]  Yu-Ming Niu,et al.  AlloDerm implants for prevention of Frey syndrome after parotidectomy: A systematic review and meta-analysis , 2012, Molecular medicine reports.

[6]  M. Wendland,et al.  Microglial Cells Contribute to Endogenous Brain Defenses after Acute Neonatal Focal Stroke , 2011, The Journal of Neuroscience.

[7]  C. Matute,et al.  Glutamate and Atp Signalling in White Matter Pathology , 2022 .

[8]  B. Conti,et al.  The activation of P2X7 receptor induces cathepsin D‐dependent production of a 20‐kDa form of IL‐1β under acidic extracellular pH in LPS‐primed microglial cells , 2011, Journal of neurochemistry.

[9]  K. Kawahara,et al.  Functional significance of the negative-feedback regulation of ATP release via pannexin-1 hemichannels under ischemic stress in astrocytes , 2011, Neurochemistry International.

[10]  S. Skaper Ion channels on microglia: therapeutic targets for neuroprotection. , 2011, CNS & neurological disorders drug targets.

[11]  G. Burnstock,et al.  Microglia: proliferation and activation driven by the P2X7 receptor. , 2010, The international journal of biochemistry & cell biology.

[12]  R. North,et al.  New structure enlivens interest in P2X receptors , 2010, Trends in pharmacological sciences.

[13]  S. Sugama,et al.  P2X7 Receptor Signaling Pathway as a Therapeutic Target for Neurodegenerative Diseases , 2010, Archivum Immunologiae et Therapiae Experimentalis.

[14]  S. Skaper,et al.  The P2X7 purinergic receptor: from physiology to neurological disorders , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[15]  M. E. Frizzo,et al.  Effects of Acute Perinatal Asphyxia in the Rat Hippocampus , 2010, Cellular and Molecular Neurobiology.

[16]  G. Hajnóczky,et al.  SR/ER-mitochondrial local communication: calcium and ROS. , 2009, Biochimica et biophysica acta.

[17]  S. Sugama,et al.  The role of the P2X7 receptor signaling pathway for the release of autolysosomes in microglial cells , 2009, Autophagy.

[18]  F. Abdul-Karim,et al.  Activation of P2X7-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice , 2009, BMC Cancer.

[19]  C. Reid,et al.  The P2X7 Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore , 2009, The Journal of Neuroscience.

[20]  C. Dinarello,et al.  Immunological and inflammatory functions of the interleukin-1 family. , 2009, Annual review of immunology.

[21]  R. North,et al.  Signaling at purinergic P2X receptors. , 2009, Annual review of physiology.

[22]  Qi-yue Deng,et al.  Downregulation of P2X7 receptor expression in rat oligodendrocyte precursor cells after hypoxia ischemia , 2009, Glia.

[23]  Geoffrey Burnstock,et al.  Purinergic signalling in the nervous system: an overview , 2009, Trends in Neurosciences.

[24]  B. Sperlágh,et al.  Up-regulation of P2X7 receptor-immunoreactivity by in vitro ischemia on the plasma membrane of cultured rat cortical neurons , 2008, Neuroscience Letters.

[25]  M. Marcoli,et al.  Functional evidence for presynaptic P2X7 receptors in adult rat cerebrocortical nerve terminals , 2008, FEBS letters.

[26]  S. Sugama,et al.  Lysophospholipids and ATP Mutually Suppress Maturation and Release of IL-1β in Mouse Microglial Cells Using a Rho-Dependent Pathway1 , 2008, The Journal of Immunology.

[27]  K. Takata,et al.  Possible involvement of P2X7 receptor activation in microglial neuroprotection against focal cerebral ischemia in rats. , 2008, Biological & pharmaceutical bulletin.

[28]  J. Lo,et al.  Activation of P2X7 receptors decreases glutamate uptake and glutamine synthetase activity in RBA‐2 astrocytes via distinct mechanisms , 2008, Journal of neurochemistry.

[29]  S. Nielsen,et al.  Regulation of AQP4 protein expression in rat brain astrocytes: Role of P2X7 receptor activation , 2008, Brain Research.

[30]  S. Shimada,et al.  Cellular localization of P2X7 receptor mRNA in the rat brain , 2008, Brain Research.

[31]  B. Sperlágh,et al.  Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus , 2007, Neuroscience.

[32]  K. Reymann,et al.  P2 Receptor Antagonist Trinitrophenyl-Adenosine-Triphosphate Protects Hippocampus from Oxygen and Glucose Deprivation Cell Death , 2007, Journal of Pharmacology and Experimental Therapeutics.

[33]  Hyun B Choi,et al.  Modulation of the Purinergic P2X7 Receptor Attenuates Lipopolysaccharide-Mediated Microglial Activation and Neuronal Damage in Inflamed Brain , 2007, The Journal of Neuroscience.

[34]  M. Kuno,et al.  The Effects of General Anesthetics on P2X7 and P2Y Receptors in a Rat Microglial Cell Line , 2007, Anesthesia and analgesia.

[35]  P. Nicotera,et al.  Ca2+ Signals and Neuronal Death in Brain Ischemia , 2007, Stroke.

[36]  DanieleBano,et al.  Ca2+ Signals and Neuronal Death in Brain Ischemia , 2007 .

[37]  I. Chessell,et al.  P2X7 receptors on microglial cells mediate injury to cortical neurons in vitro , 2006, Glia.

[38]  Felicita Pedata,et al.  P2X7 Receptor Modulation on Microglial Cells and Reduction of Brain Infarct Caused by Middle Cerebral Artery Occlusion in Rat , 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[39]  G. Burnstock,et al.  Purinergic signalling in neuron–glia interactions , 2006, Nature Reviews Neuroscience.

[40]  M. Nedergaard,et al.  Emerging challenges of assigning P2X7 receptor function and immunoreactivity in neurons , 2006, Trends in Neurosciences.

[41]  B. Sperlágh,et al.  P2X7 receptors in the nervous system , 2006, Progress in Neurobiology.

[42]  Yuchun Zhang,et al.  Enhancement of excitatory synaptic transmission in spiny neurons after transient forebrain ischemia. , 2006, Journal of neurophysiology.

[43]  K. Reymann,et al.  Microglia response and P2 receptor participation in oxygen/glucose deprivation-induced cortical damage , 2005, Neuroscience.

[44]  O. Ottersen,et al.  Neuroprotective effects of inhibiting N-methyl-d-aspartate receptors, P2X receptors and the mitogen-activated protein kinase cascade: A quantitative analysis in organotypical hippocampal slice cultures subjected to oxygen and glucose deprivation , 2005, Neuroscience.

[45]  A. Köfalvi,et al.  Supersensitivity of P2X7 receptors in cerebrocortical cell cultures after in vitro ischemia , 2005, Journal of neurochemistry.

[46]  F. Pedata,et al.  ATP extracellular concentrations are increased in the rat striatum during in vivo ischemia , 2005, Neurochemistry International.

[47]  F. Di Virgilio,et al.  A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion. , 2005, Molecular biology of the cell.

[48]  F. Di Virgilio,et al.  P2X7 receptor: Death or life? , 2005, Purinergic Signalling.

[49]  T. Möller,et al.  Astrocyte-Derived ATP Induces Vesicle Shedding and IL-1β Release from Microglia1 , 2005, The Journal of Immunology.

[50]  S. Goldman,et al.  P2X7 receptor inhibition improves recovery after spinal cord injury , 2004, Nature Medicine.

[51]  J. Grosche,et al.  P2X7 Receptor Expression after Ischemia in the Cerebral Cortex of Rats , 2004, Journal of neuropathology and experimental neurology.

[52]  Guang-yi Zhang,et al.  Brain ischemia induces serine phosphorylation of neuronal nitric oxide synthase by Ca(2+)/calmodulin-dependent protein kinase II in rat hippocampus. , 2004, Acta pharmacologica Sinica.

[53]  G. Bernardi,et al.  Synaptic P2X7 and Oxygen/Glucose Deprivation in Organotypic Hippocampal Cultures , 2004, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[54]  Kazuhide Inoue,et al.  Production and Release of Neuroprotective Tumor Necrosis Factor by P2X7 Receptor-Activated Microglia , 2004, The Journal of Neuroscience.

[55]  Darrell R. Abernethy,et al.  International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels , 2003, Pharmacological Reviews.

[56]  G. Dubyak,et al.  Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor‐independent mechanisms , 2003, British journal of pharmacology.

[57]  C. Boucsein,et al.  Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro , 2003, The European journal of neuroscience.

[58]  N. Rothwell,et al.  Role of P2X7 Receptors in Ischemic and Excitotoxic Brain Injury In Vivo , 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[59]  S. Duan,et al.  P2X7 Receptor-Mediated Release of Excitatory Amino Acids from Astrocytes , 2003, The Journal of Neuroscience.

[60]  J. Deuchars,et al.  Purinergic receptors: An ATP-gated ion channel at the cell nucleus , 2002, Nature.

[61]  A. Kharlamov,et al.  Suramin reduces infarct volume in a model of focal brain ischemia in rats , 2002, Experimental Brain Research.

[62]  N. Rothwell,et al.  Extracellular ATP and P2X7 receptors in neurodegeneration. , 2002, European journal of pharmacology.

[63]  J. Deuchars,et al.  Involvement of P2X7 receptors in the regulation of neurotransmitter release in the rat hippocampus , 2002, Journal of neurochemistry.

[64]  R. North Molecular physiology of P2X receptors. , 2002, Physiological reviews.

[65]  B S Khakh,et al.  International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. , 2001, Pharmacological reviews.

[66]  G. Bernardi,et al.  Glucose deprivation and chemical hypoxia: neuroprotection by P2 receptor antagonists , 2001, Neurochemistry International.

[67]  R. North,et al.  Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor , 1999, The Journal of physiology.

[68]  C. Brosnan,et al.  Cutting edge: purinergic signaling regulates radical-mediated bacterial killing mechanisms in macrophages through a P2X7-independent mechanism. , 1999, Journal of immunology.

[69]  J. Watters,et al.  Recent patents on novel P2X(7) receptor antagonists and their potential for reducing central nervous system inflammation. , 2010, Recent patents on CNS drug discovery.

[70]  T. Möller,et al.  Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia. , 2005, Journal of immunology.