Penetration depth of optical frequency domain imaging at wavelengths of 1310 nm and 1550 nm

We evaluate the image penetration depth of optical-frequency domain imaging into the biomedical tissue at longer wavelengths. The light sources are fiber laser at the center wavelength of 1310 nm and at the center wavelength of 1550 nm. These sources provide frequency scan rate of up to 8 kHz over a wavelength range of 110 nm at 1310 nm with ~10 μm axial resolution and a wavelength range of 150 nm at 1550 nm with ~12 μm axial resolution. OCT tomograms of soft and hard tissues acquired at 1310 nm are compared to those obtained at 1550 nm.