MECHANISMS OF RESISTANCE TO ANTICANCER AGENTS.

[1]  R. W. Brockman,et al.  A biochemical basis for resistance of L1210 mouse leukemia to 6-thioguanine. , 1963, Biochemical pharmacology.

[2]  M. Friedkin.  ENZYMATIC ASPECTS OF FOLIC ACID. , 1963, Annual review of biochemistry.

[3]  L. Law,et al.  DNA transformation studies with mammalian cells in culture. , 1962, Journal of cellular and comparative physiology.

[4]  L. Herzenberg,et al.  Characterization of resistance to amethopterin, 8-azaguanine and several fluorinated pyrimidines in the murine lymphocytic neoplasm, P388. , 1962, Journal of cellular and comparative physiology.

[5]  J. Davidson,et al.  Purine nucleotide pyrophosphorylases in 8-azaguanine-sensitive and-resistant P388 leukemias. , 1962, Journal of the National Cancer Institute.

[6]  J. Webb,et al.  The Structures of Mitomycins A, B and C and Porfiromycin--Part I , 1962 .

[7]  A. Tulinsky.  The Structure of Mitomycin A , 1962 .

[8]  R. W. Brockman,et al.  Purine ribonucleotide pyrophosphorylase activity and resistance to purine analogs in P388 murine lymphocytic leukemia , 1962 .

[9]  R. Barclay,et al.  Effects of 6-diazo-5-oxo-L-norleucine on the incorporation of precursors into nucleic acids. , 1962, Cancer research.

[10]  A. Häggmark.  Studies on resistance against 5-fluorouracil. II. Thymidylate synthetase from drug-resistant tumor lines. , 1962 .

[11]  P. R. Srinivasan,et al.  3-Enolpyruvylshikimate 5-phosphate, an intermediate in the biosynthesis of anthranillate. , 1962, Proceedings of the National Academy of Sciences of the United States of America.

[12]  E. Moore,et al.  Reduction of cytidine nucleotides to deoxycytidine nucleotides by mammalian enzymes. , 1962, Biochimica et biophysica acta.

[13]  W. Prusoff,et al.  Decrease of sensitivity to ultraviolet radiation of Streptococcus faecalis grown in media supplemented with 6-azathymine, an analog of thymine. , 1962, Biochimica et biophysica acta.

[14]  J. Carbon.  The inhibition of polynucleotide phosphorylase by 6-mercaptopurine riboside 5'-diphosphate. , 1962, Biochemical and biophysical research communications.

[15]  H. Skipper,et al.  Experimental evaluation of potential anticancer agents. IX. The ribonucleosides and ribonucleotides of two purine antagonists. , 1962, Cancer research.

[16]  M. Rabinowitz,et al.  Actinomycin D Inhibition of Deoxyribonucleic Acid-Dependent Synthesis of Ribonucleic Acid , 1962, Science.

[17]  W. E. Barnett,et al.  Induced phenotypic reversion by 8-azaguanine and 5-fluorouracil. , 1962, Biochemical and biophysical research communications.

[18]  W. Mueller,et al.  On the inhibition of RNA synthesis by actinomycin. , 1962, Biochemical and biophysical research communications.

[19]  H. Kersten.  Action of mitomycin C on nucleic acid metabolism in tumor and bacterial cells. , 1962, Biochimica et biophysica acta.

[20]  M. Grunberg‐Manago,et al.  The action of polynucleotide phosphorylase on 5-halogenouridine-5' pyrophosphates. , 1962, Biochimica et biophysica acta.

[21]  P. Bianchi.  Thymidine phosphorylation and deoxyribonucleic acid synthesis in human leukaemic cells. , 1962, Biochimica et biophysica acta.

[22]  G. Pfleiderer,et al.  Isozymes and Heteroenzymes , 1962 .

[23]  G. G. Kelley,et al.  The effects of a series of 9-alkylpurines on the growth of sensitive and 6-MP-resistant H. Ep. 2 cells. , 1962, Cancer research.

[24]  S. Cohen,et al.  The activity of nucleoside phosphorylase on 1-beta-D-arabinosyluracil within Escherichia coli. , 1962, The Journal of biological chemistry.

[25]  L. Bennett,et al.  Studies related to the mode of action of actinomycin D. , 1962, Biochemical pharmacology.

[26]  S. Benzer,et al.  Reversal of mutant phenotypes by 5-fluorouracil: an approach to nucleotide sequences in messenger-RNA. , 1962, Proceedings of the National Academy of Sciences of the United States of America.

[27]  A. Kornberg,et al.  Enzymatic synthesis of deoxyribonucleic acid. X. Influence of bromouracil substitutions on replication. , 1962, Proceedings of the National Academy of Sciences of the United States of America.

[28]  M. Reid,et al.  Chromatographic studies of purine metabolism. V. Inhibition mechanism of diazo-oxo-norleucine in wild-type and in diazo-oxo-norleucine-resistant Escherichia coli. , 1962, The Journal of biological chemistry.

[29]  H. G. Mandel,et al.  Some effects of 5-bromouracil on a thymine-requiring mutant of Escherichia coli. , 1962, Biochemical pharmacology.

[30]  T. Hsu,et al.  Properties of L cells resistant to 5-bromodeoxyuridine. , 1962, Experimental cell research.

[31]  J. M. Lampkin-Hibbard.  Effect of steroids and fluorinated pyrimidines, alone and in combination, in a lymphocytic neoplasm, sensitive and resistant to steroids in the same mouse. , 1962, Journal of the National Cancer Institute.

[32]  Greenberg Gr,et al.  Deoxyuridylate kinase activity and deoxyuridinetriphosphatase in Escherichia coli. , 1962 .

[33]  L. Bennett,et al.  Some effects of 4-aminopyrazolo(3:4-d)pyrimidine on purine metabolism☆ , 1962 .

[34]  B. I. Grosser,et al.  Comparision of cortisol metabolism by two variants of cultured fibroblasts. , 1962, Archives of biochemistry and biophysics.

[35]  W. Prusoff,et al.  Effect of 5-iodo-2'-deoxyuridine on the biosynthesis of phosphorylated derivatives of thymidine. , 1962, Biochemical pharmacology.

[36]  J. Speyer,et al.  Synthetic polynucleotides and the amino acid code. IV. , 1962, Proceedings of the National Academy of Sciences of the United States of America.

[37]  P. Reichard,et al.  Studies on resistance against 5-fluorouracil. I. Enzymes of the uracil pathway during development of resistance. , 1962, Cancer research.

[38]  A. Hori,et al.  Resistance to 6-mercaptopurine. I. Biochemical differences between the Ehrlich ascites carcinoma and a 6-mercaptopurine-resistant subline. , 1962, Canadian journal of biochemistry and physiology.

[39]  R. Miller,et al.  Biosynthesis of the purines. 27. N-(5-Amino-1-ribosyl-4-imidazolylcarbonyl)-L-aspartic acid 5'-phosphate kinosynthetase. , 1962, The Journal of biological chemistry.

[40]  A. Paterson.  Resistance to 6-mercaptopurine. II. The synthesis of thioinosinate in a 6-mercaptopurine-resistant subline of the Ehrlich ascites carcinoma. , 1962, Canadian journal of biochemistry and physiology.

[41]  A. Hampton.  Studies of the action of adenylosuccinase with 6-thio analogues of adenylosuccinic acid. , 1962, The Journal of biological chemistry.

[42]  A. Sartorelli,et al.  Observations on the site of 6-chloropurine-induced inhibition of purine biosynthesis , 1962 .

[43]  F. M. Huennekens,et al.  Increased Level of Dihydrofolic Reductase in Leucocytes of Patients Treated with Amethopterin , 1962, Nature.

[44]  J. Jacquez.  Permeability of Ehrlich Cells to Uracil, Thymine and Fluorouracil.∗ , 1962, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[45]  J. Montgomery,et al.  The 2'(3')-Phosphates of 6-Mercaptopurine Ribonucleoside and 8-Azaguanosine1 , 1962 .

[46]  M. Chamberlin,et al.  DEOXYRIBONUCLEIC ACID-DIRECTED SYNTHESIS OF RIBONUCLEIC ACID BY AN ENZYME FROM ESCHERICHIA COLI , 1962 .

[47]  J. H. Sherman,et al.  Enzymatic degradation of azaserine. , 1962, Cancer Research.

[48]  A. Mathias,et al.  The metabolism of thymidine by murine leukemic lymphoblasts (L5178Y). , 1962, Biochemical pharmacology.

[49]  M. Grunberg‐Manago.  Enzymatic synthesis of nucleic acids. , 1962, Annual review of biochemistry.

[50]  P. Calabresi,et al.  Chemotherapy of neoplastic diseases. , 1962, Annual review of medicine.

[51]  M. Tatibana,et al.  Formation of 2-azaadenine and 2, 6-diaminopurine analogues of adenosine triphosphate in human erythrocytes. , 1962, Biochimica et biophysica acta.

[52]  E. P. Anderson,et al.  Azaserine resistance in a plasma-cell neoplasm without change in active transport of the inhibitor. , 1962, Cancer research.

[53]  Y. Sakamoto,et al.  On the action mechanism of mitomycin C. , 1961, Biochemical and biophysical research communications.

[54]  M. R. Atkinson,et al.  Substrate Specificity and Inhibition of Nicotinamide Mononucleotide–Adenylyl Transferase of Liver Nuclei : Possible Mechanism of Effect of 6-Mercaptopurine on Tumour Growth , 1961, Nature.

[55]  M. Jones,et al.  Further studies on the mechanism of action of 6-thioguanine. , 1961, Cancer research.

[56]  P. T. Condit,et al.  On the Site of Action of Amethopterin , 1961, Science.

[57]  W. Prusoff,et al.  5-Bromo-2'-deoxycytidine (BCDR). II. Studies with murine neoplastic cells in culture and in vitro. , 1961, Biochemical pharmacology.

[58]  C. Heidelberger,et al.  Studies on fluorinated pyrimidines. XIII. Inhibition of thymidylate synthetase. , 1961, The Journal of biological chemistry.

[59]  J. Greenberg,et al.  Resistance and cross-resistance of Escherichia coli mutants to antitumour agent mitomycin C. , 1961, Journal of general microbiology.

[60]  D. Elson,et al.  The reversible release of protein, ribonucleic acid and deoxyribonuclease from ribosomes. , 1961, Biochimica et biophysica acta.

[61]  G. P. Kalle,et al.  Alterations in purine nucleotide pyrophosphorylases and resistance to purine analogues. , 1961, Biochimica et biophysica acta.

[62]  E. Kempner.  The selection and utilization of metabolic analogs for nucleic acid synthesis. , 1961, Biochimica et biophysica acta.

[63]  J. Butler,et al.  The thymidine phosphorylating kinases. , 1961, Biochimica et biophysica acta.

[64]  J. H. Matthaei,et al.  Characteristics and stabilization of DNAase-sensitive protein synthesis in E. coli extracts. , 1961, Proceedings of the National Academy of Sciences of the United States of America.

[65]  A. Sartorelli,et al.  Comparative studies on the in vivo action of 6-chloropurine, 6-chloropurine ribonucleoside, and 6-chloro-9-ethylpurine on sarcoma 180 ascites cells. , 1961, The Journal of pharmacology and experimental therapeutics.

[66]  S. Osawa,et al.  The effect of 8-azaguanine on the ribonucleic acid of the ribosomes in Bacillus cereus. , 1961, Journal of molecular biology.

[67]  Y. Miura,et al.  Studies on the metabolism of rat-ascites-tumor with nitrogen mustard sensitive and resistant strains. III. On the incorporation of labelled amino acids into protein in vitro. , 1961, Journal of biochemistry.

[68]  Y. Miura,et al.  Studies on the metabolism of rat ascites tumor with nitrogen mustard sensitive and resistant strains. VI. Inhibition of the in vitro incorporation of C-14-orotic acid into nucleic acids by nitrogen mustard. , 1961, Journal of biochemistry.

[69]  Marshall W. Nirenberg,et al.  The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides , 1961, Proceedings of the National Academy of Sciences.

[70]  P. D. Lawley,et al.  The reaction of mono- and di-functional alkylating agents with nucleic acids. , 1961, The Biochemical journal.

[71]  P. Reichard,et al.  Studies on a possible regulatory mechanism for the biosynthesis of deoxyribonucleic acid. , 1961, The Journal of biological chemistry.

[72]  P. Reichard.  The biosynthesis of deoxyribonucleic acid by the chick embryo. IV. Formation of deoxycytidine and deoxyguanosine phosphates with soluble enzymes. , 1961, The Journal of biological chemistry.

[73]  S. Nadler,et al.  The effect of 6-mercaptopurine on the incorporation of labeled amino acids into cellular protein of chronic granulocytic leukemia leukocytes. , 1961, Blood.

[74]  M. Weigert,et al.  On the metabolic effects of 6-chloropurine. , 1961, Cancer research.

[75]  A. Shatkin,et al.  Effect of Actinomycin D on Cellular Nucleic Acid Synthesis and Virus Production , 1961, Science.

[76]  P. R. Srinivasan,et al.  The biosynthesis of p-aminobenzoic acid: studies on the origin of the amino group. , 1961, Biochimica et biophysica acta.

[77]  M. Brooks.  236 Nicotine inhibition of normal cell growth through lowered oxidation states , 1961 .

[78]  R. Franklin,et al.  Effect of mitomycin C on the growth of some animal viruses. , 1961, Proceedings of the National Academy of Sciences of the United States of America.

[79]  L. Journey,et al.  Electron microscope studies on HeLa cell lines sensitive and resistant to actinomycin D. , 1961, Cancer research.

[80]  G. P. Kalle,et al.  Mechanism of resistance to 2,6-diaminopurine in Salmonella typhimurium. , 1961, Biochimica et biophysica acta.

[81]  P. Reichard,et al.  Uridine and deoxyuridine phosphorylases from Ehrlich ascites tumor. , 1961, Biochimica et biophysica acta.

[82]  Fischer Ga.  Increased levels of folic acid reductase as a mechanism of resistance to amethopterin in leukemic cells. , 1961 .

[83]  H. Holzer,et al.  Wirkung carcinostatischer äthylenimin-verbindungen auf den DPN-gehalt therapieresistener tumoren☆ , 1961 .

[84]  J. Burchenal,et al.  Symposium on the experimental pharmacology and clinical use of anti metabolites , 1961 .

[85]  S. Benzer,et al.  AMBIVALENT rII MUTANTS OF PHAGE T4. , 1961, Proceedings of the National Academy of Sciences of the United States of America.

[86]  G. G. Kelley,et al.  Biochemical aspects of Resistance to 6-Mercaptopurine in Human Epidermoid Carcinoma Cells in Culture , 1961, Nature.

[87]  H. Kersten,et al.  Degradation of Deoxyribonucleic Acid in Escherichia coli Cells treated with Mitomycin C , 1961, Nature.

[88]  D. P. Burma,et al.  Further studies on deoxyribonucleic acid-dependent enzymatic synthesis of ribonucleic acid. , 1961, Proceedings of the National Academy of Sciences of the United States of America.

[89]  T. Hsu,et al.  Relative stability to thermal denaturation of deoxyribonucleic acid (DNA) preparations containing bromodeoxyuridine. , 1961, Biochemical and biophysical research communications.

[90]  J. Montgomery,et al.  Synthesis of Potential Anticancer Agents. XXVII. The Ribonucleotides of 6-Mercaptopurine and 8-Azaguanine2 , 1961 .

[91]  J. Montgomery,et al.  Synthesis of Potential Anticancer Agents. XXVIII. Simple Esters of 6-Mercaptopurine Ribonucleotide2 , 1961 .

[92]  N. Okamoto,et al.  Studies on the Metabolism of Rat-Ascites-Tumor with Nitrogen Mustard Sensitive and Resistant Strains:I. On the Aerobic and Anaerobic Glycolysis , 1961 .

[93]  S. Nadler,et al.  Chemical Interaction of S35-6-Mercaptopurine and Ribonucleic Acids.∗ , 1961, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[94]  N. Okamoto,et al.  Studies on the metabolism of rat-ascites-tumor with nitrogen mustard sensitive and resistant strains. II. On the oxygen consumption and oxidative phosphorylation. , 1961, Journal of biochemistry.

[95]  A. Nishimura,et al.  Studies on the metabolism of ratascites-tumors with nitrogen mustard sensitive and resistant strains. IV. On the distribution of various enzymes in the cells of normal liver, regenerating liver and hepatoma. , 1961, Journal of biochemistry.

[96]  N. Okamoto,et al.  Studies on the metabolism of rat-ascites-tumor with nitrogen mustard sensitive and resistant strains. I. On the aerobic and anaerobic glycolysis. , 1961, Journal of biochemistry.

[97]  W. E. Magee,et al.  Studies with psicofuranine in the tumor-bearing rat. , 1961, Cancer research.

[98]  J. Monod,et al.  Genetic regulatory mechanisms in the synthesis of proteins. , 1961, Journal of molecular biology.

[99]  M. Jones,et al.  Purinethiols as feedback inhibitors of purine synthesis in ascites tumor cells. , 1961, Cancer research.

[100]  A. M. Williams,et al.  Development of Mouse Ascites Tumour Sublines Resistant to Triethylene Melamine , 1961, British Journal of Cancer.

[101]  H. Hiatt,et al.  Unstable Ribonucleic Acid Revealed by Pulse Labelling of Escherichia Coli , 1961, Nature.

[102]  J. Holland.  Part VIII. Folic acid antagonists , 1961 .

[103]  D. P. Burma,et al.  Deoxyribonucleic acid-dependent incorporation of nucleotides from nucleoside triphosphates into ribonucleic acid. , 1961, Proceedings of the National Academy of Sciences of the United States of America.

[104]  T. Nakamoto,et al.  On the participation of DNA in RNA biosynthesis. , 1961, Proceedings of the National Academy of Sciences of the United States of America.

[105]  M. Kligerman,et al.  Initial clinical studies with 5-iodo-2'-deoxyuridine. , 1961, Cancer research.

[106]  D. Hutchison,et al.  Purine Ribonucleotide Pyrophosphorylases and Resistance to Purine Analogues in Streptococcus faecalis , 1961 .

[107]  P. K. Smith,et al.  On the mechanism of action of the alkylating agents. I. Interaction of alkylating agents with nucleic acids. , 1961, Cancer research.

[108]  M. Rachmeler,et al.  Limited thymidine uptake in Escherichia coli due to an inducible thymidine phosphorylase. , 1961, Biochimica et biophysica acta.

[109]  A. Aronson.  The inhibition of bacteriophage protein synthesis by 5-fluorouracil. , 1961, Biochimica et biophysica acta.

[110]  A. Aronson.  The effect of 5-fluorouracil on bacterial protein and ribonucleic acid synthesis. , 1961, Biochimica et biophysica acta.

[111]  J. Hurwitz,et al.  The directing role of DNA in RNA synthesis. Specificity of the deoxyadenylate deoxythymidvlate copolymer as a primer. , 1961, Biochemical and biophysical research communications.

[112]  J. Hurwitz,et al.  The directing role of DNA in RNA synthesis. , 1961, Biochemical and biophysical research communications.

[113]  Raymond L. Blakley,et al.  Dihydrofolic Reductase from Streptococcus faecalis R , 1961 .

[114]  M. L. Eidinoff,et al.  Administration of 5-iododeoxyuridine-I-131 in the mouse and rat. , 1961, Cancer research.

[115]  P. Hanawalt,et al.  The normal DNA replication cycle. II. , 1961, Journal of molecular biology.

[116]  A. Williams.  Relation of atheroma to local trauma. , 1961, The Journal of pathology and bacteriology.

[117]  D. Kvam,et al.  Effect of triphosphate nucleosides of 8-azaguanine, 6-thioguanine, and 6-mercaptopurine on amino acid incorporation in vitro into microsomal protein. , 1961, The Journal of biological chemistry.

[118]  P. Reichard,et al.  Formation of deoxycytidine phosphates from cytidine phosphates in extracts from Escherichia coli. , 1961, The Journal of biological chemistry.

[119]  W. Szybalski,et al.  Genetic transformation studies. II. Radiation sensitivity of halogen labeled DNA. , 1961, Biochemical and biophysical research communications.

[120]  W. Kersten.  Interaction of actinomycin C with constituents of nucleic acids. , 1961, Biochimica et biophysica acta.

[121]  R. B. Hurlbert,et al.  Role of glutamine in the biosynthesis of cytidine nucleotides in Escherichia coli. , 1961, Biochimica et biophysica acta.

[122]  R. Tencer.  The effect of 5-fluorodeoxyuridine on amphibian embryos. , 1961, Experimental cell research.

[123]  N. Brock,et al.  [On the relation between the chemical composition and the cancerotoxic effect in a series of phosphamide esters of bis-(beta-chloroethyl)-a mine]. , 1961, Arzneimittel-Forschung.

[124]  M. Hakala,et al.  Relation of folic acid reductase to amethopterin resistance in cultured mammalian cells. , 1961, The Journal of biological chemistry.

[125]  N. Kaplan,et al.  Effect of azaserine on the biosynthesis of diphosphopyridine nucleotide in mouse. , 1961, The Journal of biological chemistry.

[126]  Raymond L. Blakley,et al.  The biosynthesis of thymidylic acid. I. Preliminary studies with extracts of Streptococcus faecalis R. , 1961, The Journal of biological chemistry.

[127]  W. C. Werkheiser.  Specific Binding of 4-Amino Folic Acid Analogues by Folic Acid Reductase , 1961 .

[128]  J. Wyngaarden,et al.  6-Mercaptopurine as substrate and inhibitor of xanthine oxidase , 1961 .

[129]  G. Hitchings,et al.  The Incorporation of 6-Mercaptopurine-S35 into the Nucleic Acids of Sensitive and Nonsensitive Transplantable Mouse Tumors , 1961 .

[130]  E. Moore,et al.  Biosynthesis of RNA cytosine and RNA purines: differential inhibition by diazo-oxonorleucine. , 1961, Cancer research.

[131]  T. D. Brock,et al.  REVERSAL OF AZASERINE BY PHENYLALANINE , 1961, Journal of bacteriology.

[132]  A. Goldin,et al.  Increased Dihydrofolate Reductase Activity as a Possible Basis of Drug Resistance in Leukæmia , 1961, Nature.

[133]  F. Šorm,et al.  Fermentative preparation of 8-azaguanosine , 1961 .

[134]  A. Sartorelli,et al.  4-aminopyrazolo(3,4-d)pyrimidine. An inhibitor of the synthesis of purines and proteins in ehrlich ascites cells. , 1961 .

[135]  H. Hiatt,et al.  Molecular and biological characterization of messenger RNA. , 1961, Cold Spring Harbor symposia on quantitative biology.

[136]  G. R. Barker,et al.  Derivatives of 5-bromouridine as substrates for ribonuclease and polynucleotid phosphorylase. , 1961, Biochimica et biophysica acta.

[137]  G. M. Timmis.  Antagonists Of Purine And Pyrimidine Metabolites And Of Folk Acid , 1962 .

[138]  J. Hurwitz,et al.  The enzymatic incorporation of ribonucleotides into RNA and the role of DNA. , 1961, Cold Spring Harbor symposia on quantitative biology.

[139]  J. Monod,et al.  Teleonomic mechanisms in cellular metabolism, growth, and differentiation. , 1961, Cold Spring Harbor symposia on quantitative biology.

[140]  J. F. Henderson,et al.  The metabolism of 4-aminopyrazolo(3,4-d)pyrimidine in normal and neoplastic tissues. , 1961, Cancer research.

[141]  R. Handschumacher,et al.  Alterations in pyrimidine metabolism in L5178Y leukemia cells resistant to 6-azauridine. , 1961, Cancer research.

[142]  W. Kersten,et al.  Zur Wirkungsweise von Actinomycinen , 1960 .

[143]  L. Slechta.  Inhibition of xanthosine-5′-phosphate aminase by psicofuranine , 1960 .

[144]  D. E. Duggan,et al.  The metabolism of 6-chloropurine-8-C14 in the rat. , 1960, The Journal of pharmacology and experimental therapeutics.

[145]  J. Jacquez,et al.  Permeability of Ehrlich Ascites Cells to Adenine.∗ , 1960, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[146]  M. L. Eidinoff,et al.  Growth inhibition of chick-embryo cells by some 5-fluorinated pyrimidines: effect on Rous sarcoma virus infection. , 1960, Journal of the National Cancer Institute.

[147]  H. Rogers,et al.  5-Fluorouracil and mucopeptide biosynthesis by Staphylococcus aureus. , 1960, The Biochemical journal.

[148]  M. L. Eidinoff,et al.  Mechanism of growth inhibition of H.Ep. 1 cells by 5-fluorodeoxycytidine and 5-fluorodeoxyuridine. , 1960, Cancer research.

[149]  R. Rueckert,et al.  Studies on unbalanced growth in tissue culture. I. Induction and consequences of thymidine deficiency. , 1960, Cancer research.

[150]  P. D. Lawley,et al.  The reaction of mustard gas with nucleic acids in vitro and in vivo. , 1960, The Biochemical journal.

[151]  M. Lane,et al.  Development of a Leukæmia resistant to Cyclophosphamide (‘Cytoxan’) , 1960, Nature.

[152]  ROY L. KISLIUK.  Reduced Folic Acid Analogues as Antimetabolites , 1960, Nature.

[153]  F. M. Huennekens,et al.  Dihydrofolic reductase in human leukemic leukocytes , 1960 .

[154]  O. Sköld.  Uridine Kinase from Ehrlich Ascites Tumor: Purification and Properties , 1960 .

[155]  A. Sartorelli,et al.  Utilization of preformed purines by sarcoma 180 or hepatoma 134 cells treated with 6-chloropurine or a combination of 6-chloropurine and azaserine. , 1960, Biochemical pharmacology.

[156]  J. Adler,et al.  Enzymatic synthesis of deoxyribonucleic acid. VII. Synthesis of a polymer of deoxyadenylate and deoxythymidylate. , 1960, The Journal of biological chemistry.

[157]  D. Hutchison,et al.  GENETIC STUDIES ON AMETHOPTERIN RESISTANCE IN DIPLOCOCCUS PNEUMONIAE , 1960, Journal of bacteriology.

[158]  A. Sartorelli,et al.  Inhibition of the biosynthesis of purines de novo by 6-chloropurine and azaserine in sensitive and naturally resistant ascites cells. , 1960, Biochemical pharmacology.

[159]  E. Chargaff,et al.  Effects of fluoropyrimidines on the synthesis of bacterial proteins and nucleic acids. , 1960, The Journal of biological chemistry.

[160]  Waksman Sa.  The actinomycins and their importance in the treatment of tumors in animals and man. Introduction. , 1960 .

[161]  Woodruff Hb,et al.  The actinomycins and their importance in the treatment of tumors in animals and man. Historical background. , 1960 .

[162]  Å. Bertler,et al.  “Bound” and “Free” Catecholamines in the Brain , 1960 .

[163]  H. Brockmann.  STRUCTURAL DIFFERENCES OF THE ACTINOMYCINS AND THEIR DERIVATIVES , 1960 .

[164]  Handschumacher Re.  Orotidylic Acid Decarboxylase: Inhibition Studies with Azauridine 5'-Phosphate , 1960 .

[165]  D. Visser,et al.  Synthesis of 5-chlorodeoxyuridine and a comparative study of 5-halodeoxyuridines in E. coli. , 1960, Biochemical pharmacology.

[166]  N. Carey,et al.  The metabolism of 6-mercaptopurine by Bacillus cereus. , 1960, Biochemical pharmacology.

[167]  A. Paterson.  Thiopurine nucleotide synthesis in a 6-MP-resistant subline of the Ehrlich ascites carcinoma and growth inhibition by certain antimetabolites. , 1960, Canadian journal of biochemistry and physiology.

[168]  L. Journey,et al.  IN VITRO STUDIES WITH HELA CELL LINES SENSITIVE AND RESISTANT TO ACTINOMYCIN D , 1960, Annals of the New York Academy of Sciences.

[169]  A. Munch-Petersen.  Formation in vitro of deoxyadenosine triphosphate from deoxyadenosine in Ehrlich ascites cells. , 1960, Biochemical and biophysical research communications.

[170]  L. Slechta.  Studies on the mode of action of psicofuranine. , 1960, Biochemical pharmacology.

[171]  W. Prusoff,et al.  The effect of 5-iododeoxyuridine upon the growth of some transplantable rodent tumors. , 1960, Cancer research.

[172]  A. Paterson.  The development of resistance to 6-mercaptopurine in a subline of the Ehrlich ascites carcinoma. , 1960, Canadian journal of biochemistry and physiology.

[173]  Günter Schmidt‐Kastner.  THE PRODUCTION OF ACTINOMYCINS BY CONTROLLED BIOSYNTHESES: THE F ACTINOMYCINS , 1960, Annals of the New York Academy of Sciences.

[174]  C. Pomerat,et al.  Possible mechanisms to explain the action of actinomycin on nonmalignant and malignant cells. , 1960, Antibiotics & chemotherapy.

[175]  A. W. Johnson,et al.  THE CHEMISTRY OF ACTINOMYCIN D AND RELATED COMPOUNDS , 1960, Annals of the New York Academy of Sciences.

[176]  C. Hackmann.  THE EFFECT OF ACTINOMYCINS ON EXPERIMENTAL TUMORS , 1960, Annals of the New York Academy of Sciences.

[177]  E. Otaka.  Effect of 8-azaguanine on ribonucleic acid and protein synthesis in Bacillus cereus, NCTC 569. , 1960, Experimental cell research.

[178]  E. Katz.  BIOGENESIS OF THE ACTINOMYCINS * , 1960, Annals of the New York Academy of Sciences.

[179]  E. Chargaff,et al.  Severe Distortion by 5-Bromouracil of the Sequence Characteristics of a Bacterial Deoxyribonucleic Acid , 1960, Nature.

[180]  D. Kvam,et al.  Inhibition of hepatic-induced enzyme formation by 8-azaguanine. , 1960, The Journal of biological chemistry.

[181]  C. A. Nichol,et al.  Evidence for a single enzyme reducing folate and dihydrofolate. , 1960, The Journal of biological chemistry.

[182]  W. Szybalski,et al.  GENETICS OF HUMAN CELL LINES III. INCORPORATION OF 5-BROMO- AND 5-IODODEOXYHRIDINE INTO THE DEOXYRIBONUCLEIC ACID OF HUMAN CELLS AND ITS EFFECT ON RADIATION SENSITIVITY , 1960 .

[183]  R. Abrams,et al.  Conversion of cytidine 5'-phosphate to deoxycytidine 5'-phosphate in cell-free mammalian extracts. , 1960, Biochemical and biophysical research communications.

[184]  D. Hutchison,et al.  Transformation of Resistance to 8-Azaguanine in Diplococcus pneumoniae , 1960, Nature.

[185]  S. B. Weiss.  ENZYMATIC INCORPORATION OF RIBONUCLEOSIDE TRIPHOSPHATES INTO THE INTERPOLYNUCLEOTIDE LINKAGES OF RIBONUCLEIC ACID. , 1960, Proceedings of the National Academy of Sciences of the United States of America.

[186]  M. Sekiguchi,et al.  Effect of mitomycin C on the synthesis of bacterial and viral deoxyribonucleic acid. , 1960, Biochimica et biophysica acta.

[187]  H. Kersten,et al.  Action of Nucleic Acids on the Inhibition of Growth by Actinomycin of Neurospora crassa , 1960, Nature.

[188]  A. Stevens.  Incorporation of the adenine ribonucleotide into RNA by cell fractions from E. coli B , 1960 .

[189]  J. Hurwitz,et al.  The enzymic incorporation of ribonucleotides into polyribonucleotides and the effect of DNA , 1960 .

[190]  Mandel Hg,et al.  The differential effect of 8-azaguanine on cell wall and protoplasmic protein synthesis in Bacillus cereus. , 1960 .

[191]  Mandel Hg,et al.  The depression of the incorporation of sulfur amino acids into Bacillus cereus by 8-Azaguanine. , 1960 .

[192]  N. Lee.  The suppression of induced enzyme formation in mammalian liver by structural analogs of purine and by aminopterin. , 1960, Cancer research.

[193]  L. Haňka.  MECHANISM OF ACTION OF PSICOFURANINE , 1960, Journal of bacteriology.

[194]  G. P. Wheeler,et al.  Prevention of the inhibitory effects of urethan, formamide, and N-methylformamide on the growth of Escherichia coli. , 1960, Biochemical pharmacology.

[195]  P. Reichard.  Formation of deoxyguanosine 5-phosphate from guanosine 5-phosphate with enzymes from chick embryos. , 1960, Biochimica et biophysica acta.

[196]  E. Maxwell,et al.  ANTIBIOTIC EFFECT OF STEROIDS ON SACCHAROMYCES FRAGILIS AND THE ISOLATION OF A RESISTANT MUTANT. , 1960, Journal of bacteriology.

[197]  C. Heidelberger,et al.  Studies on Fluorinated Pyrimidines XI . In Vitro Studies on Tumor Resistance , 2006 .

[198]  I. Hirono.  Non-Protein Sulphydryl Group in the Original Strain and Sub-line of the Ascites Tumour resistant to Alkylating Reagents , 1960, Nature.

[199]  P. Ove,et al.  Enzyme studies with mutant mammalian cells. , 1960, The Journal of biological chemistry.

[200]  J. M. Lampkin-Hibbard.  Response of a localized lymphocytic neoplasm of the mouse to 9alpha-fluorohydrocortisone and related steroids. , 1960, Journal of the National Cancer Institute.

[201]  M. Yčas,et al.  A RIBONUCLEIC ACID FRACTION FROM YEAST RELATED IN COMPOSITION TO DESOXYRIBONUCLEIC ACID. , 1960, Proceedings of the National Academy of Sciences of the United States of America.

[202]  J. M. Lampkin-Hibbard.  Development of 9alpha-fluorohydrocortisone resistance in 9alpha-fluorohydrocortisone-sensitive lymphosarcoma of the mouse. , 1960, Journal of the National Cancer Institute.

[203]  R. W. Brockman.  A mechanism of resistance to 6-mercaptopurine: metabolism of hypoxanthine and 6-mercaptopurine by sensitive and resistant neoplasms. , 1960, Cancer research.

[204]  G. Hems.  Chemical Effects of Ionizing Radiation on Deoxyribonucleic Acid in Dilute Aqueous Solution , 1960, Nature.

[205]  W. Prusoff,et al.  Studies in the mouse of the pharmacology of 5-iododeoxyuridine, an analogue of thymidine. , 1960, Biochemical pharmacology.

[206]  B. Magasanik,et al.  Guanosine 5'-phosphate reductase and its role in the interconversion of purine nucleotides. , 1960, The Journal of biological chemistry.

[207]  M. L. Eidinoff,et al.  Introduction of the 5-halogenated uracil moiety into deoxyribonucleic acid of mammalian cells in culture. , 1960, The Journal of biological chemistry.

[208]  H. Chantrenne,et al.  Action de la 8-azaguanine sur la synthèse des protéines et des acides nucléiques chez Bacillus cereus , 1960 .

[209]  W. Prusoff.  Incorporation of iododeoxyuridine into the deoxyribonucleic acid of mouse Ehrlich-ascites-tumor cells in vivo. , 1960, Biochimica et biophysica acta.

[210]  A. Wacker,et al.  Über den Einbau von 5-Bromcytosin und 5-Bromuracil in die Bakterien-Desoxyribonukleinsäure* , 1960 .

[211]  G. Lepage.  Incorporation of 6-thioguanine into nucleic acids. , 1960, Cancer research.

[212]  Handschumacher Re.  Azauracil ribonucleoside and ribonucleotides: isolation and chemical synthesis. , 1960 .

[213]  A. Tomasz,et al.  THE MECHANISM OF BACTERIAL FRAGILITY PRODUCED BY 5-FLUOROURACIL: THE ACCUMULATION OF CELL WALL PRECURSORS. , 1960, Proceedings of the National Academy of Sciences of the United States of America.

[214]  T. Iijima,et al.  Mutagenic Action of Mitomycin C on Escherichia coli , 1960, Nature.

[215]  D. Hutchison,et al.  Studies on the mechanism of action of 6-mercaptopurine in cell-free preparations. , 1960, The Journal of biological chemistry.

[216]  H. Barner,et al.  The metabolism of exogenously supplied nucleotides by Escherichia coli. , 1960, The Journal of biological chemistry.

[217]  C. Heidelberger,et al.  Studies on fluorinated pyrimidines. IX. The degradation of 5-fluorouracil-6-C14. , 1960, The Journal of biological chemistry.

[218]  J. Davidson.  Studies on the mechanism of action of 6-mercaptopurine in sensitive and resistant L1210 leukemia in vitro. , 1960, Cancer research.

[219]  L. Aronow,et al.  Studies on drug resistance in mammalian cells. II. 6-Mercaptopurine resistance in mouse fibroblasts. , 1960, The Journal of pharmacology and experimental therapeutics.

[220]  H. O. Kammen,et al.  Formation of Cytidine Nucleotides from Uridine Nucleotides by Soluble Mammalian Enzymes: Requirements for Glutamine and Guanosine Nucleotides , 1960 .

[221]  D. Karnofsky,et al.  Effects of 5-Fluorodeoxyuridine and Related Halogenated Pyrimidines on the Sand-Dollar Embryo , 1960, The Journal of biophysical and biochemical cytology.

[222]  P. Reichard,et al.  Formation of deoxycytidine 5'-phosphate from cytidine 5'-phosphate with enzymes from Escherichia coli. , 1960, Biochimica et biophysica acta.

[223]  P. Feigelson,et al.  The effects of 8-azaguanine and 6-mercaptopurine on purine catabolism in the rat. , 1958, Acta - Unio Internationalis Contra Cancrum.

[224]  O. Sköld.  Enzymes of uracil metabolism in tissues with different growth characteristics , 1960 .

[225]  E. Maxwell,et al.  Formation of testosterone acetate by Saccharomyces fragilis , 1960 .

[226]  A. Shatkin,et al.  Bacteriocidal action of mitomycin C. , 1960, Biochimica et biophysica acta.

[227]  J. Kirk.  The mode of action of actinomycin D. , 1960, Biochimica et biophysica acta.

[228]  R. Smellie,et al.  Studies on the biosynthesis of deoxyribonucleic acid by extracts of mammalian cells. IV. The phosphorylation of thymidine. , 1960, Biochimica et biophysica acta.

[229]  L. Kozloff.  Biochemistry of viruses. , 1960, Annual review of biochemistry.

[230]  M. L. Eidinoff,et al.  Introduction of the 5-ioduracil moiety into deoxyribonucleic acid of mammalian cells. , 1960, The Journal of biological chemistry.

[231]  N. Morris,et al.  Studies concerning inhibition of the synthesis of deoxycytidine by phosphorylated derivatives of thymidine. , 1960, Biochimica et biophysica acta.

[232]  V. Habermann.  Elimination by the urine of orotic acid and orotidine in man after application of 6-azauracil. , 1960, Biochimica et biophysica acta.

[233]  M. Gordon,et al.  Effects of halogenated pyrimidines on the growth of tobacco mosaic virus. , 1960, Biochimica et biophysica acta.

[234]  H. Klenow,et al.  The effect of some purine deoxyribosides on the incorporation of [14C] formate and [32P] orthophosphate into DNA of ascites tumor cells in vitro. , 1960, Biochimica et biophysica acta.

[235]  R. W. Brockman,et al.  Metabolism of uracil and 5-fluorouracil by drug-sensitive and by drug-resistant bacteria. , 1960, Biochimica et biophysica acta.

[236]  P. Alexander.  Radiation-imitating chemicals. , 1960, Scientific American.

[237]  E. Chargaff,et al.  Patterns of cellular controls operating in bacteriophage reproduction. II. Effect of 5-fluorouracil on metabolic events in bacteria infected with coliphage T2r. , 1960, Biochimica et biophysica acta.

[238]  D. Visser,et al.  Synthesis of protein and DNA in Escherichia coli treated with 5-bromodeoxyuridine. , 1960, Biochimica et biophysica acta.

[239]  E. P. Anderson,et al.  Purification and properties of a leukemic cell phosphodiesterase. , 1960, Biochimica et biophysica acta.

[240]  W. Prusoff.  Studies on the mechanism of action of 5-iododeoxyuridine, an analog of thymidine. , 1960, Cancer research.

[241]  R. Sinsheimer.  The biochemistry of genetic factors. , 1960, Annual review of biochemistry.

[242]  E. Moore,et al.  Reduction of 5'-cytidylic acid to deoxycytidylic acid by mammalian enzymes. , 1960, Biochimica et biophysica acta.

[243]  B. Magasanik,et al.  The biosynthesis of the imidazole ring of histidine. , 1960, The Journal of biological chemistry.

[244]  Thomas Rc,et al.  Psicofuranine. VIII. Some pharmacological observations. , 1959 .

[245]  R. Herrmann,et al.  Reactions involving the carbon--nitrogen bond: heterocyclic compounds. , 1959, Journal of cellular and comparative physiology.

[246]  M. Gordon,et al.  Studies on the incorporation of 5-fluorouracil into a virus nucleic acid. , 1959, Biochimica et biophysica acta.

[247]  A. Anton,et al.  Studies on the nature of resistance of Streptococcus faecalis to folic acid antagonists. , 1959, Biochemical pharmacology.

[248]  W. Prusoff,et al.  Inhibition of the growth of mouse leukemia cells in culture by 5-iododeoxyuridine. , 1959, Biochimica et biophysica acta.

[249]  M. Hakala.  Mode of action of 5-bromodeoxyuridine on mammalian cells in culture. , 1959, The Journal of biological chemistry.

[250]  M. Hakala,et al.  Studies on the mode of action of 6-mercaptopurine and its ribonucleoside on mammalian cells in culture. , 1959, The Journal of biological chemistry.

[251]  P. Feigelson,et al.  Cellular xanthine oxidase and uricase levels in leukemic and normal mouse leukocytes. , 1959, Cancer research.

[252]  W. Szybalski.  Genetics of human cell lines. II. Method for determination of mutation rates to drug resistance. , 1959, Experimental cell research.

[253]  S. Cohen,et al.  Virus-induced acquisition of metabolic function. III. Formation and some properties of thymidylate synthetase of bacteriophage-infected Escherichia coli. , 1959, The Journal of biological chemistry.

[254]  R. Handschumacher,et al.  The biochemical activity of 6-azauridine: interference with pyrimidine metabolism in transplantable mouse tumors. , 1959, The Journal of biological chemistry.

[255]  A. J. Guarino,et al.  The conversion of guanine to hypoxanthine in rat-liver extracts. , 1959, Biochimica et biophysica acta.

[256]  E. Chargaff,et al.  Massive Incorporation of 5-Fluorouracil into a Bacterial Ribonucleic Acid , 1959, Nature.

[257]  M. Sekiguchi,et al.  Induction of Phage Formation in the Lysogenic Escherichia coli K-12 by Mitomycin C , 1959, Nature.

[258]  L. Aronow.  Studies on drug resistance in mammalian cells. I. Amethopterin resistance in mouse fibroblasts. , 1959, The Journal of pharmacology and experimental therapeutics.

[259]  J. Gots,et al.  Specific Action of Adenine as a Feedback Inhibitor of Purine Biosynthesis , 1959, Science.

[260]  B. R. Baker.  Potential anti-cancer agents--II. A proposed mechanism for the anti-cancer action of L-azaserine and 6-diazo-5-oxo-L-norleucine. , 1959, Biochemical pharmacology.

[261]  H. Skipper,et al.  A mechanism of resistance to 8-azaguanine. II. Studies with experimental neoplasms. , 1959, Cancer research.

[262]  A. Paterson.  THE FORMATION OF 6-MERCAPTOPURINE RIBOSIDE PHOSPHATE IN ASCITES TUMOR CELLS , 1959 .

[263]  E. Sarcione,et al.  6-Methylmercaptopurine , 1959, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[264]  C. Carter.  Reaction of 6-mercaptopurine with inosine- and guanosine-5'-phosphate pyrophosphorylase purified from E. coli. , 1959, Biochemical pharmacology.

[265]  W. Szybalski,et al.  Genetics of Human Cell Lines I. 8-Azaguanine Resistance, a Selective “Single-Step” Marker.∗ , 1959, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[266]  J. Gots,et al.  Purine Analogs as Feedback Inhibitors.∗ † , 1959, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[267]  N. Kaplan,et al.  Formation of the nicotinic acid analogue of diphosphopyridine nucleotide after nicotinamide administration. , 1959, The Journal of biological chemistry.

[268]  M. L. Eidinoff,et al.  Pyrimidine studies. II. Effect of 5-bromodeoxyuridine and related nucleosides on incorporation of precursors into nucleic acid pyrimidines. , 1959, Cancer research.

[269]  M. L. Eidinoff,et al.  Growth inhibition of a human tumor cell strain by 5-fluorocytidine and 5-fluoro-2'-deoxycytidine: reversal studies. , 1959, Cancer research.

[270]  H. O. Kammen,et al.  The formation of cytidine nucleotides and RNA cytosine from orotic acid by the Novikoff tumor in vitro. , 1959, Cancer research.

[271]  M. L. Eidinoff,et al.  Incorporation of 5-Iodouracil labelled with Iodine-131 into the Deoxyribonucleic Acid of Human Leukæmic Leucocytes following in vivo Administration of 5-Iododeoxyuridine labelled with Iodine-131 , 1959, Nature.

[272]  M. L. Eidinoff,et al.  Incorporation of Unnatural Pyrimidine Bases into Deoxyribonucleic Acid of Mammalian Cells , 1959, Science.

[273]  J. C. Reid,et al.  6-Thiouric Acid—a Metabolite of 6-Mercaptopurine , 1959 .

[274]  G. Hitchings,et al.  Studies on Condensed Pyrimidine Systems. XXI. The Isolation and Synthesis of 6-Mercapto-2,8-purinediol (6-Thiouric Acid) , 1959 .

[275]  E. Freese.  The specific mutagenic effect of base analogues on Phage T4 , 1959 .

[276]  Montgomery Ja.  The relation of anticancer activity to chemical structure: a review. , 1959 .

[277]  J. Wyngaarden,et al.  The regulation of activity of phosphoribosyl-pyrophosphate amidotransferase by purine ribonacleotides: a potential feedback control of purine biosyntoesis. , 1959, The Journal of biological chemistry.

[278]  F. Šorm,et al.  Inhibition of Escherichia coli polynucleotide phosphorylase by 6-azauridine diphosphate. , 1959, Biochimica et biophysica acta.

[279]  J. Burchenal,et al.  The effects of 5-fluorodeoxycytidine, 5-fluorodeoxyuridine, and related compounds on transplanted mouse leukemias. , 1959, Cancer research.

[280]  H. Skipper,et al.  Decreased ribonucleotide pyrophosphorylase activity of Streptococcus faecalis and L1210 leukaemia resistant to purine antagonists , 1959 .

[281]  J. Jacquez,et al.  Resistance in L1210 ascites without change in concentrative uptake of o-diazoacetyl-L-serine or 6-diazo-5-oxo-L-norleucine. , 1959, Cancer research.

[282]  J. L. Way,et al.  Polyphosphate nucleosides of purine analogues. , 1959, The Journal of biological chemistry.

[283]  C. Markert,et al.  MULTIPLE FORMS OF ENZYMES: TISSUE, ONTOGENETIC, AND SPECIES SPECIFIC PATTERNS. , 1959, Proceedings of the National Academy of Sciences of the United States of America.

[284]  C. Heidelberger,et al.  Studies on fluorinated pyrimidines. VIII. Further biochemical and metabolic investigations. , 1959, The Journal of biological chemistry.

[285]  A. D. Welch.  The problem of drug resistance in cancer chemotherapy. , 1959, Cancer research.

[286]  H. Skipper,et al.  Structure-activity relationships and cross-resistance observed on evaluation of a series of purine analogs against experimental neoplasms. , 1959, Cancer research.

[287]  M. Sekiguchi,et al.  Synthesis of Deoxyribonucleic Acid by Phage-infected Escherichia coli in the Presence of Mitomycin C , 1959, Nature.

[288]  J. Kawamata,et al.  Selective Inhibition of Formation of Deoxyribonucleic Acid in Escherichia coli by Mitomycin C , 1959, Nature.

[289]  G. Klein,et al.  Possible Enzymic Mechanism for the Development of Resistance against Fluorouracil in Ascites Tumours , 1959, Nature.

[290]  H. Hoeksema,et al.  A NEW ANTIBIOTIC, 6-AMINO-9-D-PSICOFURANOSYLPURINE , 1959 .

[291]  P. R. Srinivasan.  THE ENZYMATIC SYNTHESIS OF ANTHRANILIC ACID FROM SHIKIMIC ACID-5-PHOSPHATE AND L-GLUTAMINE1 , 1959 .

[292]  W. Szybalski,et al.  Mutagenic Effect of Azaserine in Relation to Azaserine Resistance in Escherichia coli , 1959, Science.

[293]  C. Heidelberger,et al.  Studies on fluorinated pyrimidines: VII—the degradative pathway☆☆☆ , 1959 .

[294]  S. C. Lyster,et al.  Potentiation of biological activities of steroids by carcinogenic hydrocarbons. , 1959, Endocrinology.

[295]  E. Canellakis,et al.  Studies on the biosynthesis of deoxyribonucleic acid by soluble mammalian enzymes. , 1959, The Journal of biological chemistry.

[296]  H. Skipper,et al.  A mechanism of resistance to 8-azaguanine. I. Microbiological studies on the metabolism of purines and 8 azapurines. , 1959, Cancer research.

[297]  F. Šorm,et al.  The accumulation of orotic acid, uracil and hypoxanthine by Escherichia coli in the presence of 6-azauracil and the biosynthesis of 6-azauridylic acid , 1959 .

[298]  H. Chantrenne.  La 8-azaguanine provoque-t-elle la formation de protéines anormales? , 1959 .

[299]  R. Ellison,et al.  Some aspects of the metabolism of 5-bromouracil , 1959 .

[300]  R. Abrams,et al.  Biosynthesis of nucleic acid purines. III. Guanosine 5′-phosphate formation from xanthosine 5′-phosphate and l-glutamine , 1959 .

[301]  M. Richmond.  Effect of inhibitors on lytic enzyme synthesis by Bacillus subtilis R , 1959 .

[302]  S C HARTMAN,et al.  Nucleic acids, purines, pyrimidines (nucleotide synthesis). , 1959, Annual review of biochemistry.

[303]  D. M. Greenberg,et al.  Studies on folic acid reduction. , 1959, Biochimica et biophysica acta.

[304]  W. Prusoff.  Synthesis and biological activities of iododeoxyuridine, an analog of thymidine. , 1959, Biochimica et biophysica acta.

[305]  H. Klenow.  On the effect of some adenine derivatives on the incorporation in vitro of isotopically labelled compounds into the nucleic acids of Ehrlich ascites tumor cells. , 1959, Biochimica et biophysica acta.

[306]  M. Hakala,et al.  The ability of purine and thymine derivatives and of glycine to support the growth of mammalian cells in culture. , 1959, The Journal of biological chemistry.

[307]  K. Sugiura.  Studies in a tumor spectrum. VIII. The effect of mitomycin C on the growth of a variety of mouse, rat, and hamster tumors. , 1959, Cancer research.

[308]  A. Sartorelli,et al.  Effects of A-methopterin on the purine biosynthesis of susceptible and resistant TA3 ascites cells. , 1958, Cancer research.

[309]  J. Jacquez.  Concentrative uptake of 6-Diazo-5-Oxo-L-Norleucine by Sarcoma 180, Liver and Muscle in vivo. ∗ † , 1958, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[310]  D. M. Greenberg,et al.  Studies on the conversion of deoxyuridylic acid to thymidylic acid by a soluble extract from rat thymus. , 1958, Archives of biochemistry and biophysics.

[311]  M. Potter.  VARIATION IN RESISTANCE PATTERNS IN DIFFERENT NEOPLASMS , 1958, Annals of the New York Academy of Sciences.

[312]  A. Sartorelli,et al.  Metabolic effects of 6-thioguanine. II. Biosynthesis of nucleic acid purines in vivo and in vitro. , 1958, Cancer research.

[313]  A. Gierer,et al.  Production of Mutants of Tobacco Mosaic Virus by Chemical Alteration of its Ribonucleic Acid in vitro , 1958, Nature.

[314]  A. Rich,et al.  A SYNTHESIS OF RIBOTHYMIDINE-5'-PYROPHOSPHATE AND ITS CONVERSION TO POLYRIBOTHYMIDYLIC ACID. , 1958, Proceedings of the National Academy of Sciences of the United States of America.

[315]  R. Dutton,et al.  Effect of 8-Azaguanine on Antibody Synthesis in vitro , 1958, Nature.

[316]  E. K. Pine.  Concentrative uptake of azaserine by neoplastic plasma cells and lymphocytes. , 1958, Journal of the National Cancer Institute.

[317]  R. Handschumacher,et al.  Inhibition of orotidylic acid decarboxylase, a primary site of carcinostasis by 6-azauracil. , 1958, Biochimica et biophysica acta.

[318]  H. Skipper,et al.  Chromatographic studies of purine metabolism. III. Effects of A-methopterin on formate-C14 utilization in mice bearing susceptible and dependent L1210 leukemia. , 1958, Archives of biochemistry and biophysics.

[319]  A. Sartorelli,et al.  Metabolic effects of 6-thioguanine. I. Studies on thioguanine-resistant and-sensitive Ehrlich ascites cells. , 1958, Cancer research.

[320]  Handschumacher Re.  Bacterial preparation of orotidine-5'-phosphate and uridine-5'-phosphate. , 1958 .

[321]  Seymour S. Cohen,et al.  THE MODE OF ACTION OF 5-FLUOROURACIL AND ITS DERIVATIVES. , 1958, Proceedings of the National Academy of Sciences of the United States of America.

[322]  R. Schindler,et al.  Comparative utilization by sarcoma-180 cells in culture of 14C-labelled uracil, 6-azauracil, and their ribosides , 1958 .

[323]  F. M. Huennekens,et al.  Enzymatic reduction of dihydrofolic acid. , 1958, The Journal of biological chemistry.

[324]  H. O. Kammen,et al.  Amination of uridine nucleotides to cytidine nucleotides by soluble mammalian enzymes; role of glutamine and guanosine nucleotides. , 1958, Biochimica et biophysica acta.

[325]  E. C. Moore,et al.  The metabolism of 6-thioguanine in normal and neoplastic tissues. , 1958, Cancer research.

[326]  Slotnick Ij.  Studies on the mechanism of action of actinomycin D. II. Interference with ammonia assimilation and adaptive enzyme formation. , 1958 .

[327]  A. Sartorelli,et al.  Inhibition of ascites cell growth by combinations of 6-thioguanine and azaserine. , 1958, Cancer research.

[328]  J. Holland,et al.  Experiments with some mouse tumors and leukemias. , 1958, Cancer research.

[329]  L. Law.  SOME ASPECTS OF DRUG RESISTANCE IN NEOPLASMS , 1958, Annals of the New York Academy of Sciences.

[330]  P. Handler,et al.  Biosynthesis of diphosphopyridine nucleotide. II. Enzymatic aspects. , 1958, The Journal of biological chemistry.

[331]  V. Potter,et al.  Incorporation of thymidine into deoxyribonucleic acid by enzymes from rat tissues. , 1958, The Journal of biological chemistry.

[332]  F. M. Huennekens,et al.  Folic Acid Coenzymes , 1958, Science.

[333]  J. Adler,et al.  Proceedings of the NATIONAL ACADEMY OF SCIENCES Volume 44 Number 7 July 15 , 1958 ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID . III . THE INCORPORATION OF PYRIMIDINE AND PURINE ANALOGUES INTO DEOXYRIBONUCLEIC ACID , 2022 .

[334]  U. Lagerkvist.  Biosynthesis of guanosine 5'-phosphate. I. Xanthosine 5'-phosphate as an intermediate. , 1958, The Journal of biological chemistry.

[335]  H. Mandel.  Effect of 8-azaguanine on utilization of methionine by B. cereus. , 1958, Archives of biochemistry and biophysics.

[336]  D. M. Greenberg,et al.  Dihydrofolic Acid Reductase , 1958, Nature.

[337]  M. Potter,et al.  Response to cortisone and development of cortisone resistance in a cortisone-sensitive lymphosarcoma of the mouse. , 1958, Journal of the National Cancer Institute.

[338]  R. Markham,et al.  The effects of 8-azaguanine on the biosynthesis of ribonucleic acid in Bacillus cereus. , 1958, The Biochemical journal.

[339]  H. Tarr.  Lingcod muscle purine nucleoside phosphorylase. , 1958, Canadian journal of biochemistry and physiology.

[340]  S. Kit,et al.  Effect of 5-bromodeoxyuridine on deoxyribonucleic acid-thymine synthesis and cell metabolism of lymphatic tissues and tumors. , 1958, Cancer research.

[341]  W. Szybalski,et al.  THE MECHANISM OF CHEMICAL MUTAGENESIS. I. KINETIC STUDIES ON THE ACTION OF TRIETHYLENE MELAMINE (TEM) AND AZASERINE. , 1958, Proceedings of the National Academy of Sciences of the United States of America.

[342]  M. Baliś,et al.  Metabolism of resistant mutants of Streptococcus faecalis. III. The action of 6-mercaptopurine. , 1958, Cancer research.

[343]  D. Stone,et al.  The effects of deoxycorticosterone and other steroids on Neurospora crassa. , 1958, Archives of biochemistry and biophysics.

[344]  H. Marumo,et al.  Isolation of new fractions of antitumor mitomycins. , 1958, Antibiotics & chemotherapy.

[345]  A. Sartorelli,et al.  The development and biochemical characterization of resistance to azaserine in a TA 3 ascites carcinoma. , 1958, Cancer research.

[346]  Jack J. Fox,et al.  Thiation of Nucleosides. I. Synthesis of 2-Amino-6-mercapto-9-β-D-ribofuranosylpurine (“Thioguanosine”) and Related Purine Nucleosides1 , 1958 .

[347]  D. Karnofsky.  APPENDIX Structural Formulas of Principal Compounds Used Clinically , 1958 .

[348]  W. Ross.  IN VITRO REACTIONS OF BIOLOGICAL ALKYLATING AGENTS , 1958, Annals of the New York Academy of Sciences.

[349]  C. Price.  FUNDAMENTAL MECHANISMS OF ALKYLATION , 1958, Annals of the New York Academy of Sciences.

[350]  C. Heidelberger,et al.  Studies on fluorinated pyrimidines. III. The metabolism of 5-fluorouracil-2-C14 and 5-fluoroorotic-2-C14 acid in vivo. , 1958, Cancer research.

[351]  C. Heidelberger,et al.  Studies on fluorinated pyrimidines. IV. Effects on nucleic acid metabolism in vivo. , 1958, Cancer research.

[352]  J. L. Way,et al.  Enzymatic synthesis of 5'-phosphate nucleotides of purine analogues. , 1958, The Journal of biological chemistry.

[353]  R. Morton.  Enzymic Synthesis of Coenzyme I in Relation to Chemical Control of Cell Growth , 1958, Nature.

[354]  F. M. Huennekens,et al.  Inhibition of Dihydrofolic Reductase by Aminopterin and Amethopterin.∗ † , 1958, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[355]  C. Heidelberger,et al.  Fluorinated Pyrimidines VI. Effects of 5-Fluorouridine and 5-Fluoro-2′-Deoxyuridine on Transplanted Tumors.∗ † , 1958, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[356]  D. Hutchison,et al.  Metabolism of resistant mutants of Streptococcus faecalis. II. Incorporation of exogenous purines. , 1958, Cancer research.

[357]  J. Davidson,et al.  The metabolism of pyrazolo (3,4-d) pyrimidines by the rat. , 1958, Cancer research.

[358]  D. Hutchison.  Metabolism of resistant mutants of Streptococcus faecalis. I. Isolation and characterization of the mutants. , 1958, Cancer research.

[359]  C. Huggins,et al.  EFFECTS OF 3-METHYLCHOLANTHRENE ON THE ENDOCRINE SYSTEM AND METABOLISM OF THE RAT AND ITS INFLUENCE TO RETARD GROWTH OF MAMMARY TUMORS HITHERTO REFRACTORY , 1958, The Journal of experimental medicine.

[360]  F. Šorm,et al.  Mechanism of the cancerostatic action of 6-azauracil and its riboside , 1958 .

[361]  J. Davoll.  318. The synthesis of the v-triazolo[d]pyrimidine analogues of adenosine, inosine, guanosine, and xanthosine, and a new synthesis of guanosine , 1958 .

[362]  M. L. Eidinoff,et al.  Pyrimidine Studies I. Effect of DON (6-Diazo-5-oxo-l-norleucine) on Incorporation of Precursors into Nucleic Acid Pyrimidines , 1958 .

[363]  C. A. Nichol,et al.  On the enzymic reduction of folic acid by a purified hydrogenase. , 1958, Biochimica et biophysica acta.

[364]  F. Šorm,et al.  Accumulation of nucleic acid metabolites in Escherichia coli exposed to the action of 6-azauracil. , 1958, Biochimica et biophysica acta.

[365]  W. E. Razzell,et al.  Purification and properties of a pyrimidine deoxyriboside phosphorylase from Escherichia coli. , 1958, Biochimica et biophysica acta.

[366]  B. Wright,et al.  The role of polyglutamyl pteridine coenzymes in serine metabolism. III. The enzymatic formation of dihydrofolic acid and dihydroteropterin. , 1958, The Journal of biological chemistry.

[367]  Ernest,et al.  Enzymatic synthesis of deoxyribonucleic acid. , 1969, Harvey lectures.

[368]  C. Stock,et al.  A comparative study of 6-diazo-5-oxo-L-norleucine and O-diazoacety-L-serine on sarcoma 180. , 1957, Antibiotics & chemotherapy.

[369]  H. Skipper,et al.  Studies with mustards. III. In vivo fixation of C14 from nitrogen mustard-C14H3 in nucleic acid fractions of animal tissues. , 1957, Archives of biochemistry and biophysics.

[370]  P. D. Lawley.  The relative reactivities of deoxyribonucleotides and of the bases of DNA towards alkylating agents. , 1957, Biochimica et biophysica acta.

[371]  C. Stock,et al.  Effects of combinations of azaserine and of 6-diazo-5-oxo-L-norleucine with purine analogs and other antimetabolites on the growth of two mouse mammary carcinomas. , 1957, Cancer research.

[372]  D. B. Dunn,et al.  Effects of 5-halogenated uracils on the growth of Escherichia coli and their incorporation into deoxyribonucleic acids. , 1957, The Biochemical journal.

[373]  D. Levin,et al.  The effects of 6-mercaptopurine on Lactobacillus casei. , 1957, Archives of biochemistry and biophysics.

[374]  J. Jacquez.  Active transport of O-diazoacetyl-L-serine and 6-diazo-5-oxo-L-norleucine in Ehrlich ascites carcinoma. , 1957, Cancer research.

[375]  J M BUCHANAN,et al.  Biosynthesis of the purines. XVI. The synthesis of adenosine 5'-phosphate and 5-amino-4-imidazolecarboxamide ribotide by a nucleotide pyrophosphorylase. , 1957, The Journal of biological chemistry.

[376]  M. Smith,et al.  Metabolism of 2, 6-diaminopurine; conversion to 5'-phosphoribosyl-2-methylamino-beta-aminopurine by enzymes of Escherichia coli. , 1957, The Journal of biological chemistry.

[377]  Takehiko Yamamoto,et al.  Effects of Carbon Sources and Base Analogues of Nucleic Acid on the Formation of Bacterial Amylase , 1957, Nature.

[378]  C. Heidelberger,et al.  THE SYNTHESIS OF 5-FLUOROPYRIMIDINES , 1957 .

[379]  J. Montgomery,et al.  SYNTHESIS OF POTENTIAL ANTICANCER AGENTS. X. 2-FLUOROADENOSINE1 , 1957 .

[380]  Mandel Hg,et al.  The effects of 6-mercaptopurine on biosynthesis in Escherichia coli. , 1957 .

[381]  Canellakis Es.  Pyrimidine metabolism. II. Enzymatic pathways of uracil anabolism. , 1957 .

[382]  H. Skipper,et al.  Structure-activity relationships observed on screening a series of pyrazolopyrimidines against experimental neoplasms. , 1957, Cancer research.

[383]  R. Drew.  Induction of Resistance to A-Methopterin in Diplococcus pneumoniae by Deoxyribonucleic Acid , 1957, Nature.

[384]  J. Smith,et al.  The metabolism of 8-azapurines. , 1957, The Biochemical journal.

[385]  P. K. Smith,et al.  The effect of 6-mercaptopurine on nucleic acid biosynthesis in Escherichia coli. , 1957, The Journal of pharmacology and experimental therapeutics.

[386]  W. Prusoff.  Studies on the mechanism of action of azathymine. III. Relationship between incorporation into deoxypentose nucleic acid and inhibition. , 1957, The Journal of biological chemistry.

[387]  A. Kornberg,et al.  Conversion of uracil and orotate to uridine 5'-phosphate by enzymes in lactobacilli. , 1957, The Journal of biological chemistry.

[388]  R. K. Robins,et al.  Pyrazolopyrimidines as inhibitors and substrates of xanthine oxidase. , 1957, The Journal of biological chemistry.

[389]  H. Skipper,et al.  Searches for exploitable biochemical differences between normal and cancer cells. III. Effects of aminoimidazolecarboxamide on purine metabolism. , 1957, Cancer research.

[390]  R. Barclay,et al.  The influence of N-methylformamide on formate-C14 incorporation. II. In nucleic acids of tumor-bearing rats. , 1957, Cancer research.

[391]  B. Magasanik,et al.  Enzymes essential for the biosynthesis of nucleic acid guanine; inosine 5'-phosphate dehydrogenase of Aerobacter aerogenes. , 1957, The Journal of biological chemistry.

[392]  B. Magasanik,et al.  Enzymes essential for the biosynthesis of nucleic acid guanine; xanthosine 5'-phosphate aminase of Aerobacter aerogenes. , 1957, The Journal of biological chemistry.

[393]  K. Mainzer,et al.  HORMONAL INFLUENCES ON MAMMARY TUMORS OF THE RAT , 1957, The Journal of experimental medicine.

[394]  P. Handler,et al.  Enzymatic synthesis of nicotinamide mononucleotide. , 1957, The Journal of biological chemistry.

[395]  C. Heidelberger,et al.  Fluorinated Pyrimidines, A New Class of Tumour-Inhibitory Compounds , 1957, Nature.

[396]  Mandel Hg,et al.  Fractionation studies of Bacillus cereus containing 8-azaguanine. , 1957 .

[397]  E. Snell,et al.  Pyridoxal and metal ion catalysis of alpha, beta elimination reactions of serine-3-phosphate and related compounds. , 1957, The Journal of biological chemistry.

[398]  M. Potter,et al.  Studies of a plasma-cell neoplasm of the mouse. I. Characterization of neoplasm 70429, including its sensitivity to various antimetabolites with the rapid development of resistance to azaserine, DON, and N-methylformamide. , 1957, Journal of the National Cancer Institute.

[399]  J. M. Buchanan,et al.  Biosynthesis of the purines. XV. The effect of aza-L-serine and 6-diazo-5-oxo-L-norleucine on inosinic acid biosynthesis de novo. , 1957, The Journal of biological chemistry.

[400]  Maxwell Re,et al.  6-Diazo-5-oxo-L-norleucine, a new tumor-inhibitory substance. V. Microbiologic studies of mode of action. , 1957 .

[401]  A. W. Johnson,et al.  642. Actinomycin. Part V. The structure of actinomycin D , 1957 .

[402]  L. Lukens,et al.  Enzymic formation of 6-mercaptopurine tibo tide. , 1957, Biochimica et biophysica acta.

[403]  S. Grisolía,et al.  The purification and properties of hydropyrimidine dehydrogenase. , 1957, Biochimica et biophysica acta.

[404]  L. Law,et al.  Azaguaninedeaminase activity of several lymphocytic leukemias of mice. , 1957, Journal of the National Cancer Institute.

[405]  R. Handschumacher.  Studies of bacterial resistance to 6-azauracil and its riboside. , 1957, Biochimica et biophysica acta.

[406]  P. K. Smith,et al.  The effect of 4-amino-5-imidazolecarboxamide on the incorporation of purines into liver nucleic acids of the mouse. , 1957, Biochimica et biophysica acta.

[407]  R. W. Brockman,et al.  A comparison of the metabolism of purines and purine analogs by susceptible and drug-resistant bacterial and neoplastic cells. , 1957, Biochimica et biophysica acta.

[408]  I. Lieberman.  Enzymatic synthesis of adenosine-5'-phosphate from inosine-5'-phosphate. , 1956, The Journal of biological chemistry.

[409]  E. H. Creaser.  The assimilation of amino acids by bacteria. 22. The effect of 8-azaguanine upon enzyme formation in Staphylococcus aureus. , 1956, The Biochemical journal.

[410]  J. Davidson,et al.  The inhibition of adenosine deaminase by 8-azaguanine in vitro. , 1956, The Journal of biological chemistry.

[411]  H. Skipper,et al.  Chromatographic studies of purine metabolism. I. The effect of azaserine on purine biosynthesis in E. coli using various C14-labeled precursors. , 1956, Archives of biochemistry and biophysics.

[412]  H. Skipper,et al.  Studies on the mode of action of azaserine. , 1956, Archives of biochemistry and biophysics.

[413]  D. Goldthwait.  5-Phosphoribosylamine, a precursor of glycinamide ribotide. , 1956, The Journal of biological chemistry.

[414]  Carter Ce,et al.  The preparation and properties of adenylosuccinase and adenylosuccinic acid. , 1956 .

[415]  G. Lepage,et al.  Purine biosynthesis and inhibitors in ascites cell tumors. , 1956, Cancer research.

[416]  H. Thomas,et al.  SYNTHESIS OF POTENTIAL ANTICANCER AGENTS. II.1 6-MERCAPTO-9-β-D-RIBOFURANOSYLPURINE , 1956 .

[417]  W. Rightsel,et al.  6-Diazo-5-oxo-L-norleucine, a new tumor-inhibitory substance. I. Biologic studies. , 1956, Antibiotics & chemotherapy.

[418]  R. Morton,et al.  Comparative rates of synthesis of diphosphopyridine nucleotide by normal and tumour tissue from mouse mammary gland; studies with isolated nuclei. , 1956, The Biochemical journal.

[419]  L. Law.  Differences between cancers in terms of evolution of drug resistance. , 1956, Cancer research.

[420]  H. W. Dion,et al.  6-Diazo-5-oxo-L-norleucine, A New Tumor-inhibitory Substance. II.1 Isolation and Characterization2 , 1956 .

[421]  H. Skipper,et al.  Potentiated Inhibition of Escherichia coli by Certain Combinations of Agents , 1956, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[422]  Seymour S. Cohen,et al.  STUDIES ON THE INDUCTION OF THYMINE DEFICIENCY AND ON THE EFFECTS OF THYMINE AND THYMIDINE ANALOGUES IN ESCHERICHIA COLI , 1956, Journal of bacteriology.

[423]  J. Davidson,et al.  The in vitro inhibition of xanthine dehydrogenase by 8-azaguanine. , 1956, Cancer research.

[424]  R. De Giovanni,et al.  Introduction of unnatural pyrimidines into deoxyribonucleic acid of Escherichia coli. , 1956, The Journal of biological chemistry.

[425]  N. Kaplan,et al.  Pyridine nucleotide synthesis in the mouse. , 1956, The Journal of biological chemistry.

[426]  J. Smith,et al.  Distribution of 8-Azaguanine in the Nucleic Acids of Bacillus Cereus , 1956, Nature.

[427]  G. Lepage,et al.  The influence of azaserine and 6-mercaptopurine on the in vivo metabolism of ascites tumor cells. , 1956, Cancer research.

[428]  I. Lieberman.  Enzymatic amination of uridine triphosphate to cytidine triphosphate. , 1955, The Journal of biological chemistry.

[429]  I. Hirono.  A Comparative Study of the Mode of Action of X-Rays and Alkylating Agents , 1955, Nature.

[430]  E. Korn,et al.  Biosynthesis of the purines. VII. Synthesis of nucleotides from bases by partially purified enzymes. , 1955, The Journal of biological chemistry.

[431]  J. M. Buchanan,et al.  Biosynthesis of the purines. VIII. Enzymatic synthesis and utilization of alpha-5-phosphoribosylpyrophosphate. , 1955, The Journal of biological chemistry.

[432]  E. Korn,et al.  Biosynthesis of the purines. VI. Purification of liver nucleoside phosphorylase and demonstration of nucleoside synthesis from 4-amino-5-imidazolecarboxamide, adenine, and 2, 6-diaminopurine. , 1955, The Journal of biological chemistry.

[433]  R. Abrams,et al.  TRANSFORMATION OF INOSINIC ACID TO ADENYLIC AND GUANYLIC ACIDS IN A SOLUBLE ENZYME SYSTEM1 , 1955 .

[434]  H. Skipper,et al.  Studies with mustards. II. Paper chromatography and radioautography of reaction mixtures of various compounds with S35-sulfur mustard. , 1955, Archives of biochemistry and biophysics.

[435]  H. Skipper,et al.  Studies with mustards. I. Ion-exchange chromatography of reaction mixtures of purines and pyrimidines with nitrogen mustard. , 1955, Archives of biochemistry and biophysics.

[436]  A. Kornberg,et al.  Enzymatic synthesis and properties of 5-phosphoribosylpyrophosphate. , 1955, The Journal of biological chemistry.

[437]  I. Hirono,et al.  Chromosome Features in the Original and Resistant Sublines of the Yoshida Sarcoma , 1955 .

[438]  G. Hitchings,et al.  The Synthesis of 6-Thioguanine , 1955 .

[439]  Paul A. Zahl,et al.  Effect of Aminopterin and Certain Purine Antagonists on Adenine Nucleotide Levels in Tissues of Tumor-Bearing Mice.∗ , 1955, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[440]  I. Hirono.  Some Properties of Yoshida Sarcoma Cells Resistant to Methyl-bis-(β-chlorethyl)-amine N-oxide.∗ , 1955 .

[441]  C. Carter,et al.  Enzymatic Synthesis of Adenylosuccinic Acid1 , 1955 .

[442]  R. Lundén,et al.  Enzymic Synthesis of Xanthosine- and Guanosine-5-phosphate from Inosine-5-phosphate. , 1955 .

[443]  J. M. Buchanan,et al.  Involvement of Atp, 5-Phosphoribosyl-Pyrophosphate and L-Azaserine in the Enzymatic Formation of Glycinamide Ribotide Intermediates in Inosinic Acid Biosynthesis , 1955 .

[444]  S. Mudd,et al.  l-Azaserine as an inducing agent for the development of phage in the lysogenic Escherichia coli, K-12☆ , 1955 .

[445]  M. Friedkin.  The enzymic synthesis of 6-mercaptopurine deoxyriboside. , 1955, Biochimica et biophysica acta.

[446]  G. Hitchings,et al.  THE FATE OF 6‐MERCAPTOPURINE IN MICE , 1954, Annals of the New York Academy of Sciences.

[447]  G. Hitchings,et al.  MICROBIOLOGICAL EFFECTS OF 6‐MERCAPTOPURINE , 1954, Annals of the New York Academy of Sciences.

[448]  L. Law,et al.  RESPONSE OF ACUTE LYMPHOCYTIC LEUKEMIAS TO THE PURINE ANTAGONIST 6‐MERCAPTOPURINE , 1954, Annals of the New York Academy of Sciences.

[449]  G. B. Brown.  THE BIOSYNTHESIS OF NUCLEIC ACIDS AS A BASIS FOR AN APPROACH TO CHEMOTHERAPY , 1954, Annals of the New York Academy of Sciences.

[450]  L. Law,et al.  The effect of 4-amino-5-imidazolecarboxamide on the carcinostatic action of 8-azaguanine. , 1954, Cancer research.

[451]  D. Hutchison.  BIOLOGICAL ACTIVITIES OF 6‐MERCAPTOPURINE: EFFECTS ON STREPTOCOCCUS FAECALIS , 1954, Annals of the New York Academy of Sciences.

[452]  H. Skipper.  EFFECTS OF 6‐MERCAPTOPURINE ON EXPERIMENTAL TUMORS , 1954, Annals of the New York Academy of Sciences.

[453]  H. Barner,et al.  STUDIES ON UNBALANCED GROWTH IN ESCHERICHIA COLI. , 1954, Proceedings of the National Academy of Sciences of the United States of America.

[454]  D. B. Dunn,et al.  Incorporation of Halogenated Pyrimidines into the Deoxyribonucleic Acids of Bacterium Coli and its Bacteriophages , 1954, Nature.

[455]  V. S. Nickel,et al.  Filament formation in E. coli induced by azaserine and other antineoplastic agents. , 1954, Science.

[456]  Mandel Hg,et al.  The effect of 4-amino-5-imidazolecarboxamide on the toxicity of 8-azaguanine. , 1954 .

[457]  M. Friedkin.  Enzymatic synthesis of azaguanine riboside and azaguanine desoxyriboside. , 1954, The Journal of biological chemistry.

[458]  T. Haskell,et al.  Azaserine, a New Tumor-inhibitory Substance. Isolation and Characterization1 , 1954 .

[459]  T. Haskell,et al.  Azaserine, a New Tumor-inhibitory Substance. Structural Studies.1 , 1954 .

[460]  E. Nicolaides,et al.  Azaserine, Synthetic Studies. II , 1954 .

[461]  M. Friedkin,et al.  Enzymatic synthesis of thiouracil riboside and thiouracil desoxyriboside. , 1954, The Journal of biological chemistry.

[462]  C. A. Nichol.  Studies on the mechanism of resistance to folic acid analogues in a strain of Streptococcus faecalis. , 1954, The Journal of biological chemistry.

[463]  M. Friedkin,et al.  The enzymatic synthesis of nucleosides. I. Thymidine phosphorylase in mammalian tissue. , 1954, The Journal of biological chemistry.

[464]  M. Friedkin,et al.  The enzymatic synthesis of nucleosides. II. Thymidine and related pyrimidine nucleosides. , 1954, The Journal of biological chemistry.

[465]  L. Anderson,et al.  Azaserine, A New Tumour-Inhibitory Substance: Antibiotic Studies of Azaserine , 1954, Nature.

[466]  C. Stock,et al.  Azaserine, A New Tumour-Inhibitory Substance: Studies with Crocker Mouse Sarcoma 180 , 1954, Nature.

[467]  Mandel Hg,et al.  The incorporation of 8-azaguanine into nucleic acids of tumor-bearing mice. , 1954 .

[468]  C. Stock.  Experimental cancer chemotherapy. , 1954, Advances in cancer research.

[469]  H. Skipper,et al.  Incorporation of 2,6-diaminopurine into the nucleoside phosphates of the mouse. , 1953, The Journal of biological chemistry.

[470]  L. Law.  Resistance in Leukemic Cells to an Adenine Antagonist, 6-Mercaptopurine , 1953, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[471]  C. P. Rhoads,et al.  Clinical evaluation of a new antimetabolite, 6-mercaptopurine, in the treatment of leukemia and allied diseases. , 1953, Blood.

[472]  G. Hitchings,et al.  The purine metabolism of a 6-mercaptopurine-resistant Lactobacillus casei. , 1953, The Journal of biological chemistry.

[473]  S. Sternberg,et al.  6-Mercaptopurine: effects in mouse sarcoma 180 and in normal animals. , 1953, Cancer research.

[474]  G. Hitchings,et al.  Effects of purine antagonists on a diaminopurine-resistant strain of Lactobacillus casei. , 1953, The Journal of biological chemistry.

[475]  J. Kream,et al.  Enzymatic deamination of 8-azaguanine in normal human brain and in glioblastoma multiforme. , 1953, Cancer research.

[476]  M. Flavin,et al.  Aminopurine interconversion in Tetrahymena geleii: rôle of 8-azaguanine and hypoxanthine. , 1953, The Journal of biological chemistry.

[477]  D. Levin,et al.  Purine metabolism of a diaminopurine-resistant strain of Lactobacillus casei. , 1953, The Journal of biological chemistry.

[478]  F. Crick,et al.  The structure of DNA. , 1953, Cold Spring Harbor symposia on quantitative biology.

[479]  D. Levin,et al.  Utilization of some purine riboside derivatives by Lactobacillus casei. , 1952, The Journal of biological chemistry.

[480]  L. M. Paege,et al.  Bacterial uracil riboside phosphorylase. , 1952, Archives of biochemistry and biophysics.

[481]  H. Skipper,et al.  Effects of A-methopterin on formate incorporation into the nucleic acids of susceptible and resistant leukemic cells. , 1952, Cancer research.

[482]  J. Kream,et al.  Enzymatic deamination of 8-azaguanine in normal and neoplastic tissues. , 1952, Cancer research.

[483]  D. Levin,et al.  The incorporation of exogenous purines into pentose nucleic acid by Lactobacillus casei. , 1952, The Journal of biological chemistry.

[484]  G. Kidder,et al.  The incorporation of 8-azaguanine into the nucleic acid of Tetrahymena geleii. , 1952, The Journal of biological chemistry.

[485]  L. Law.  Origin of the Resistance of Leukæmic Cells to Folic Acid Antagonists , 1952, Nature.

[486]  M. Bell,et al.  Further Studies on Formate Incorporation by Leukemic Blood Cells.∗ , 1951, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[487]  A. Kornberg,et al.  Enzymatic phosphorylation of adenosine and 2,6-diaminopurine riboside. , 1951, The Journal of biological chemistry.

[488]  G. Boyd,et al.  Preferential Incorporation of Formate Carbon into Leukemic Blood Cells as Indicated by Autoradiography.∗ , 1951, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[489]  T. Jukes,et al.  "Citrovorum factor" activity of tetrahydropteroylglutamic acid. , 1951 .

[490]  B. Lowy,et al.  A New Synthesis of Purine Nucleosides. The Synthesis of Adenosine, Guanosine and 2,6-Diamino-9-β-D-ribofuranosylpurine1 , 1951 .

[491]  R. Caputto.  The enzymatic synthesis of adenylic acid; adenosinekinase. , 1951, The Journal of biological chemistry.

[492]  G. Hitchings,et al.  Antagonists of nucleic acid derivatives. VI. Purines. , 1951, The Journal of biological chemistry.

[493]  V. Potter.  Sequential Blocking of Metabolic Pathways in vivo ∗ , 1951, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[494]  G. Hitchings,et al.  Antagonists of nucleic acid derivatives. IV. Reversal studies with 2-aminopurine and 2,6-diaminopurine. , 1950, The Journal of biological chemistry.

[495]  H. Skipper,et al.  Investigation of the Nucleic Acids of Viscera and Tumor Tissue from Animals Injected with Radioactive 8-Azaguanine , 1950 .

[496]  H. Skipper,et al.  Inhibition of nucleic acid synthesis by folic acid antagonists. , 1950, Cancer research.

[497]  L. Law,et al.  Development of Resistance to Folic Acid Antagonists in a Transplantable Lymphoid Leukemia , 1950, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[498]  W. Shive.  THE UTILIZATION OF ANTIMETABOLITES IN THE STUDY OF BIOCHEMICAL PROCESSES IN LIVING ORGANISMS , 1950, Annals of the New York Academy of Sciences.

[499]  C. A. Nichol,et al.  On the Mechanism of Action of Aminopterin.∗ , 1950, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[500]  M. Friedkin,et al.  Desoxyribose-1-phosphate: I. The phosphorolysis and resynthesis of purine desoxyribose nucleoside. , 1950, The Journal of biological chemistry.

[501]  J. Burchenal,et al.  The induction of resistance to 4-amino-N10-methylpteroylglutamic acid in a strain of transmitted mouse leukemia. , 1950, Science.

[502]  G. Kidder,et al.  Purine Metabolism in Tetrahymena and Its Relation to Malignant Cells in Mice. , 1949, Science.

[503]  M. Hultquist,et al.  Analogs of Pteroylglutamic Acid. III. 4-Amino Derivatives , 1949 .

[504]  C. P. Rhoads,et al.  Preliminary studies on the effect of 2,6‐diaminopurine on transplanted mouse leukemia , 1949, Cancer.

[505]  V. Bryson.  The Effects of Nitrogen Mustard on Escherichia coli , 1948, Journal of bacteriology.

[506]  A. Bendich,et al.  A synthesis of isoguanine labeled with isotopic nitrogen. , 1948, Journal of the American Chemical Society.

[507]  Elion Gb,et al.  Pyrimidine derivatives as antagonists of pteroylglutamic acid. , 1948 .

[508]  J. M. Smith,et al.  Analogs of pteroylglutamic acid; N(10)-alkylpteroic acid and derivatives. , 1948, Journal of the American Chemical Society.

[509]  H. Mcilwain,et al.  Relationships in streptococci between growth and metabolism of glutamine. , 1948, The Biochemical journal.

[510]  P. Dustin.  Some New Aspects of Mitotic Poisoning , 1947, Nature.

[511]  G. Hitchings,et al.  THE EFFECTS OF PYRIMIDINES ON THE GROWTH OF LACTOBACILLUS CASEI. , 1945, Science.

[512]  H. Kalckar.  ENZYMATIC SYNTHESIS OF A NUCLEOSIDE , 1945 .

[513]  R. Roblin,et al.  Studies in Chemotherapy. VIII. Methionine and Purine Antagonists and their Relation to the Sulfonamides1 , 1945 .

[514]  E. Kendall,et al.  THE INFLUENCE OF 11-DEHYDR0-17-HYDR0XYCORTICOSTERONE (COMPOUND E) ON THE GROWTH OF A MALIGNANT TUMOR IN THE MOUSE11 , 1944 .