The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation
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M. Igoillo-Esteve | M. Cnop | J. Morris | S. Hughes | L. Laar | B. Hansen | A. Clark | J. Gunter | I. Cnop | E. Koning | G. Walls | J. Morris | P. Johnson | M. Pipeleers-Marichal | M. B. Hoppa | A. Clark | D. Gray | F. Sayyed | Barbara C Hansen | F. Sayyed. | M. Pipeleers‐Marichal | L. V. D. Laar | J. H. Gunter | F. Sayyed
[1] A. LaCroix. "That which does not kill us makes us stronger". , 2009, Menopause.
[2] J. Meier. Linking the Genetics of Type 2 Diabetes With Low Birth Weight , 2009, Diabetes.
[3] J. Kushner,et al. Adaptive β-Cell Proliferation Is Severely Restricted With Advanced Age , 2009, Diabetes.
[4] Mark I. McCarthy,et al. Type 2 Diabetes Risk Alleles Are Associated With Reduced Size at Birth , 2009, Diabetes.
[5] T. Gurlo,et al. Age-Dependent Decline in β-Cell Proliferation Restricts the Capacity of β-Cell Regeneration in Mice , 2009, Diabetes.
[6] M. Büchler,et al. Impaired islet turnover in human donor pancreata with aging. , 2008, European journal of endocrinology.
[7] J. Kushner,et al. ADAPTIVE BETA CELL PROLIFERATION IS SEVERELY RESTRICTED WITH ADVANCED AGE , 2009 .
[8] T. Gurlo,et al. Age-dependent Decline in Beta Cell Proliferation Restricts the Capacity of Beta Cell Regeneration in Mice , 2009 .
[9] C. Sempoux,et al. Pancreatic β‐cell mass in European subjects with type 2 diabetes , 2008, Diabetes, obesity & metabolism.
[10] D. Sulzer,et al. Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease , 2008, Journal of neurochemistry.
[11] R. Rizza,et al. β-Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of β-Cell Mass in Humans , 2008, Diabetes.
[12] R. Mirmira. Faculty Opinions recommendation of Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans. , 2008 .
[13] K. Zaret. Faculty Opinions recommendation of Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. , 2008 .
[14] Linda Partridge,et al. Minireview Stress-response Hormesis and Aging: ''that Which Does Not Kill Us Makes Us Stronger'' Figure 1. Dose-response Curve of a Treatment with a Hormetic Effect Minireview Cell Metabolism , 2022 .
[15] R. Scharfmann,et al. β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas , 2008, Cell.
[16] W. Uhl,et al. Partial Pancreatectomy in Adult Humans Does Not Provoke β-Cell Regeneration , 2008, Diabetes.
[17] M. McCarthy,et al. Learning From Molecular Genetics Novel Insights Arising From the Definition of Genes for Monogenic and Type 2 Diabetes , 2008 .
[18] W. Uhl,et al. Partial pancreatectomy in adult humans does not provoke beta-cell regeneration. , 2008, Diabetes.
[19] R. Scharfmann,et al. Expanding human beta cells , 2008, Diabetologia.
[20] S. Savitha,et al. Carnitine and lipoate ameliorates lipofuscin accumulation and monoamine oxidase activity in aged rat heart. , 2007, European journal of pharmacology.
[21] P. Halban,et al. Proliferation of sorted human and rat beta cells , 2007, Diabetologia.
[22] Nicholas D Bonawitz,et al. Rethinking the Mitochondrial Theory of Aging: The Role of Mitochondrial Gene Expression in Lifespan Determination , 2007, Cell cycle.
[23] U. Brunk,et al. Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron. , 2007, Archives of biochemistry and biophysics.
[24] Anil Bhushan,et al. The replication of beta cells in normal physiology, in disease and for therapy. , 2007, Nature clinical practice. Endocrinology & metabolism.
[25] J. Leahy,et al. Regulation of Pancreatic β-Cell Regeneration in the Normoglycemic 60% Partial-Pancreatectomy Mouse , 2006, Diabetes.
[26] Kathrin Maedler,et al. Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1. , 2006, Diabetes.
[27] B. Hering,et al. Effect of Donor Age on Function of Isolated Human Islets , 2006, Diabetes.
[28] D. Pearce,et al. You say lipofuscin, we say ceroid: Defining autofluorescent storage material , 2006, Neurobiology of Aging.
[29] R. Rizza,et al. Relationship Between β-Cell Mass and Fasting Blood Glucose Concentration in Humans , 2006, Diabetes Care.
[30] U. Brunk,et al. Oxidative stress, accumulation of biological 'garbage', and aging. , 2006, Antioxidants & redox signaling.
[31] I. Rooman,et al. Regulation of pancreatic beta-cell mass. , 2005, Physiological reviews.
[32] J. Kushner,et al. Very Slow Turnover of β-Cells in Aged Adult Mice , 2005 .
[33] Ratan D. Bhardwaj,et al. Retrospective Birth Dating of Cells in Humans , 2005, Cell.
[34] S. Bonner-Weir,et al. New sources of pancreatic β-cells , 2005, Nature Biotechnology.
[35] De,et al. Tissue Fractionation Studies , 2005 .
[36] S. Bonner-Weir,et al. New sources of pancreatic beta-cells. , 2005, Nature biotechnology.
[37] J. Kushner,et al. Very slow turnover of beta-cells in aged adult mice. , 2005, Diabetes.
[38] S. Bonner-Weir,et al. Five stages of evolving beta-cell dysfunction during progression to diabetes. , 2004, Diabetes.
[39] W. Denk,et al. Serial Block-Face Scanning Electron Microscopy to Reconstruct Three-Dimensional Tissue Nanostructure , 2004, PLoS biology.
[40] J. Eaton,et al. Aging of Cardiac Myocytes in Culture: Oxidative Stress, Lipofuscin Accumulation, and Mitochondrial Turnover , 2004, Annals of the New York Academy of Sciences.
[41] Yuval Dor,et al. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. , 2004, Nature.
[42] C. Cobelli,et al. Erratum: Mechanisms of the age-associated deterioration in glucose tolerance: Contribution of alterations in insulin secretion, action, and clearance (Diabetes (2003) 52 (1738-1748)) , 2003 .
[43] Claudio Cobelli,et al. Mechanisms of the age-associated deterioration in glucose tolerance: contribution of alterations in insulin secretion, action, and clearance. , 2003, Diabetes.
[44] B. Pakkenberg,et al. Increased islet volume but unchanged islet number in ob/ob mice. , 2003, Diabetes.
[45] Jae-Hyoung Cho,et al. Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea , 2003 .
[46] Robert A. Rizza,et al. β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes , 2003, Diabetes.
[47] Robert A Rizza,et al. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. , 2003, Diabetes.
[48] In Kyu Lee,et al. Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea. , 2003, The Journal of clinical endocrinology and metabolism.
[49] E. Porta,et al. Sequential histochemical studies of neuronal lipofuscin in human cerebral cortex from the first to the ninth decade of life. , 2002, Archives of gerontology and geriatrics.
[50] D. L. Schmucker,et al. Quantifying dense bodies and lipofuscin during aging: a morphologist's perspective. , 2002, Archives of gerontology and geriatrics.
[51] S. Bonner-Weir. beta-cell turnover: its assessment and implications. , 2001, Diabetes.
[52] M. Oshimura,et al. Telomere shortening with aging in human liver. , 2000, The journals of gerontology. Series A, Biological sciences and medical sciences.
[53] L. Bouwens,et al. Endocytosis of low-density lipoprotein by human pancreatic beta cells and uptake in lipid-storing vesicles, which increase with age. , 2000, The American journal of pathology.
[54] M. Cnop,et al. Low density lipoprotein binding and uptake by human and rat islet beta cells. , 1997, Endocrinology.
[55] S. Bonner-Weir,et al. Dynamics of β-cell Mass in the Growing Rat Pancreas: Estimation With a Simple Mathematical Model , 1995, Diabetes.
[56] E. Porta,et al. Changes in cathepsin B and lipofuscin during development and aging in rat brain and heart. , 1995, Gerontology.
[57] J. Parsons,et al. Adaptation of islets of Langerhans to pregnancy: increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion. , 1992, Endocrinology.
[58] Robin C. Allshire,et al. Telomere reduction in human colorectal carcinoma and with ageing , 1990, Nature.
[59] Borgen La,et al. Lysosomes and pancreatic islet function: intracellular insulin degradation and lysosomal transformations. , 1986 .
[60] L. Borg,et al. Lysosomes and pancreatic islet function: intracellular insulin degradation and lysosomal transformations. , 1986, Diabetes research.
[61] P. Yates,et al. The relationship between lipofuscin pigment and ageing in the human nervous system , 1978, Journal of the Neurological Sciences.
[62] D. Harman. Aging: a theory based on free radical and radiation chemistry. , 1956, Journal of gerontology.
[63] R. Wattiaux,et al. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue. , 1955, The Biochemical journal.