The atropine-resistance of the response to intrinsic nerve stimulation of the guinea-pig bladder.

As early as 1911, Langley observed this anomalous behaviour of the bladder in the dog, cat and rabbit but until recently studies of this phenomenon in other species have been few. Burnstock & Campbell (1963) and Burnstock, O'Shea & Wood (1963) have described its occurrence in the ring-tailed possum (Pseudocheirusperegrinus) and the toad (Bufo marinus). Carpenter (1963) also noted the same results for the bladder of the rat. This paper describes studies on the response of the isolated bladder of the guinea-pig to electrical stimulation and to application of drugs.

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