NPC-16, a novel naphthalimide–polyamine conjugate, induced apoptosis and autophagy in human hepatoma HepG2 cells and Bel-7402 cells
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[1] Chang Hwa Jung,et al. mTOR regulation of autophagy , 2010, FEBS letters.
[2] 彭婕妤,et al. CHM-1, a new vascular targeting agent, induces apoptosis of human umbilical vein endothelial cells via p53-mediated death receptor 5 up-regulation. , 2010 .
[3] M. Maiuri,et al. Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1 , 2010, Oncogene.
[4] A. J. Palmer,et al. The polyamine transport system as a target for anticancer drug development , 2010, Amino Acids.
[5] Jin Zhao,et al. Conjugation of substituted naphthalimides to polyamines as cytotoxic agents targeting the Akt/mTOR signal pathway. , 2009, Organic & biomolecular chemistry.
[6] Chaojie Wang,et al. Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidine. , 2009, Toxicology.
[7] Forrest M Kievit,et al. A ligand-mediated nanovector for targeted gene delivery and transfection in cancer cells. , 2009, Biomaterials.
[8] Lynda D. Ralton,et al. Bisnaphthalimidopropyl spermidine induces apoptosis within colon carcinoma cells. , 2009, Chemico-biological interactions.
[9] T. Ikejima,et al. Involvement of PKC signal pathways in oridonin-induced autophagy in HeLa cells: a protective mechanism against apoptosis. , 2009, Biochemical and biophysical research communications.
[10] Yuan-fang Ma,et al. Synthesis, cytotoxicity and apoptosis of naphthalimide polyamine conjugates as antitumor agents. , 2009, European journal of medicinal chemistry.
[11] J. Annereau,et al. F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system. , 2008, Cancer research.
[12] G. Jönsson,et al. Molecular mechanisms underlying N1, N11-diethylnorspermine-induced apoptosis in a human breast cancer cell line , 2008, Anti-cancer drugs.
[13] Yuan-fang Ma,et al. Synergistic antitumor effects of anthracenylmethyl homospermidine and alpha-difluoromethylornithine on promyelocytic leukemia HL60 cells. , 2008, Toxicology in vitro : an international journal published in association with BIBRA.
[14] S. Oredsson,et al. Novel anti‐apoptotic effect of Bcl‐2: Prevention of polyamine depletion‐induced cell death , 2008, Cell biology international.
[15] Guang-chao Liu,et al. A novel homospermidine conjugate inhibits growth and induces apoptosis in human hepatoma cells , 2007, Acta Pharmacologica Sinica.
[16] M. Cabot,et al. Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison. , 2007, Biochemical pharmacology.
[17] L. Marton,et al. Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases , 2007, Nature Reviews Drug Discovery.
[18] J. Delcros,et al. Structure-activity investigations of polyamine-anthracene conjugates and their uptake via the polyamine transporter , 2007, Amino Acids.
[19] Jie Jin,et al. Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1. , 2007, Leukemia research.
[20] F. Lamarche,et al. Synthesis and photocytotoxic activity of new chlorin-polyamine conjugates. , 2006, Bioorganic & medicinal chemistry letters.
[21] Shaomeng Wang,et al. A small molecule compound inhibits AKT pathway in ovarian cancer cell lines. , 2006, Gynecologic oncology.
[22] J. Delcros,et al. Effect of polyamine homologation on the transport and biological properties of heterocyclic amidines. , 2006, Journal of medicinal chemistry.
[23] N. Hail. Mitochondria: A novel target for the chemoprevention of cancer , 2005, Apoptosis.
[24] A. Terman,et al. Different effects of chloroquine and hydroxychloroquine on lysosomal function in cultured retinal pigment epithelial cells , 2002, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[25] L. Penning,et al. Involvement of polyamines in apoptosis. Facts and controversies: effectors or protectors? , 2000, Seminars in cancer biology.
[26] Elizabeth Yang,et al. Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL , 1996, Cell.
[27] C. Thompson,et al. Apoptosis Meets Signal Transduction: Elimination of a BAD Influence , 1996, Cell.
[28] D. Alberts,et al. Evaluation of Amonafide in Cervical Cancer, Phase II: A SWOG Study , 1992, American journal of clinical oncology.