Cyclin-dependent kinase inhibitor p16INK4a and telomerase may co-modulate endothelial progenitor cells senescence
暂无分享,去创建一个
[1] M. Satoh,et al. Association between oxidative DNA damage and telomere shortening in circulating endothelial progenitor cells obtained from metabolic syndrome patients with coronary artery disease. , 2008, Atherosclerosis.
[2] B. Williams,et al. Angiotensin II–Mediated Oxidative DNA Damage Accelerates Cellular Senescence in Cultured Human Vascular Smooth Muscle Cells via Telomere-Dependent and Independent Pathways , 2008, Circulation research.
[3] A. Cheung,et al. Telomere dysfunction, genome instability and cancer. , 2008, Frontiers in bioscience : a journal and virtual library.
[4] J. Bartek,et al. DNA damage signalling guards against activated oncogenes and tumour progression , 2007, Oncogene.
[5] M. Malumbres,et al. Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression , 2007, Oncogene.
[6] Jian-Mei Li,et al. Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence. , 2007, Cardiovascular research.
[7] S. Artandi,et al. Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo , 2007, Proceedings of the National Academy of Sciences.
[8] Ronald A. DePinho,et al. How stem cells age and why this makes us grow old , 2007, Nature Reviews Molecular Cell Biology.
[9] T. Lange,et al. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1 , 2007, Nature.
[10] R. Langer,et al. Endothelial potential of human embryonic stem cells. , 2007, Blood.
[11] G. Ertl,et al. Differential Effects of Organic Nitrates on Endothelial Progenitor Cells Are Determined by Oxidative Stress , 2007 .
[12] M. Sumi,et al. Reconstituted High-Density Lipoprotein Stimulates Differentiation of Endothelial Progenitor Cells and Enhances Ischemia-Induced Angiogenesis , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[13] P. Poole‐Wilson,et al. Age-Dependent Impairment of Endothelial Progenitor Cells Is Corrected by Growth Hormone Mediated Increase of Insulin-Like Growth Factor-1 , 2007, Circulation research.
[14] C. Zhu,et al. Ginkgo Biloba Extract Reduces Endothelial Progenitor-Cell Senescence Through Augmentation of Telomerase Activity , 2007, Journal of cardiovascular pharmacology.
[15] Dimitris Kletsas,et al. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints , 2006, Nature.
[16] K. Ligon,et al. p16INK4a induces an age-dependent decline in islet regenerative potential , 2006, Nature.
[17] R. DePinho,et al. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a , 2006, Nature.
[18] J. Campisi,et al. Ageing: Balancing regeneration and cancer , 2006, Nature.
[19] S. Morrison,et al. Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing , 2006, Nature.
[20] T. Akasaka,et al. Hyperglycemia accelerated endothelial progenitor cell senescence via the activation of p38 mitogen-activated protein kinase. , 2006, Circulation journal : official journal of the Japanese Circulation Society.
[21] T. Akasaka,et al. Endothelial Progenitor Cell Differentiation and Senescence in an Angiotensin II-Infusion Rat Model , 2006, Hypertension Research.
[22] J. Yodoi,et al. 17β-Estradiol Protects against Oxidative Stress-induced Cell Death through the Glutathione/Glutaredoxin-dependent Redox Regulation of Akt in Myocardiac H9c2 Cells* , 2006, Journal of Biological Chemistry.
[23] Roberto Bolli,et al. Life and Death of Cardiac Stem Cells: A Paradigm Shift in Cardiac Biology , 2006, Circulation.
[24] T. Imanishi,et al. Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension , 2005, Journal of hypertension.
[25] T. Lange,et al. Shelterin: the protein complex that shapes and safeguards human telomeres , 2005 .
[26] G. Nickenig,et al. Circulating endothelial progenitor cells and cardiovascular outcomes. , 2005, The New England journal of medicine.
[27] T. Imanishi,et al. Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity , 2005, Journal of hypertension.
[28] T. Imanishi,et al. Effect of Estrogen on Differentiation and Senescence in Endothelial Progenitor Cells Derived from Bone Marrow in Spontaneously Hypertensive Rats , 2005, Hypertension Research.
[29] M. Barbacid,et al. Tumour biology: Senescence in premalignant tumours , 2005, Nature.
[30] J. Shay,et al. BRAFE600-associated senescence-like cell cycle arrest of human naevi , 2005, Nature.
[31] M. Blasco. Telomeres and human disease: ageing, cancer and beyond , 2005, Nature Reviews Genetics.
[32] S. Artandi,et al. Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer. , 2005, Biochemical and biophysical research communications.
[33] S. Fichtlscherer,et al. Reduced Number of Circulating Endothelial Progenitor Cells Predicts Future Cardiovascular Events: Proof of Concept for the Clinical Importance of Endogenous Vascular Repair , 2005, Circulation.
[34] M. Kelm,et al. Impaired progenitor cell activity in age-related endothelial dysfunction. , 2005, Journal of the American College of Cardiology.
[35] J. Campisi. Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors , 2005, Cell.
[36] T. Lange,et al. Significant Role for p16INK4a in p53-Independent Telomere-Directed Senescence , 2004, Current Biology.
[37] Chaowei Wu,et al. Regulation of cellular response to oncogenic and oxidative stress by Seladin-1 , 2004, Nature.
[38] H. Drexler,et al. Statin-Induced Improvement of Endothelial Progenitor Cell Mobilization, Myocardial Neovascularization, Left Ventricular Function, and Survival After Experimental Myocardial Infarction Requires Endothelial Nitric Oxide Synthase , 2004, Circulation.
[39] M. Hristov,et al. Endothelial progenitor cells: characterization, pathophysiology, and possible clinical relevance , 2004, Journal of cellular and molecular medicine.
[40] Leslie A. Smith,et al. Transplantation of Circulating Endothelial Progenitor Cells Restores Endothelial Function of Denuded Rabbit Carotid Arteries , 2004, Stroke.
[41] A. Zeiher,et al. Vascular repair by circulating endothelial progenitor cells: the missing link in atherosclerosis? , 2004, Journal of Molecular Medicine.
[42] T. Sawamura,et al. OXIDIZED LOW‐DENSITY LIPOPROTEIN INDUCES ENDOTHELIAL PROGENITOR CELL SENESCENCE, LEADING TO CELLULAR DYSFUNCTION , 2004, Clinical and experimental pharmacology & physiology.
[43] A. Akhmedov,et al. Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells , 2004, Journal of Cell Science.
[44] Mark A Sussman,et al. Cardiac Stem Cell and Myocyte Aging, Heart Failure, and Insulin-Like Growth Factor-1 Overexpression , 2004, Circulation research.
[45] M. Endres,et al. Physical Training Increases Endothelial Progenitor Cells, Inhibits Neointima Formation, and Enhances Angiogenesis , 2004 .
[46] Hajime Nakamura,et al. Glutaredoxin Exerts an Antiapoptotic Effect by Regulating the Redox State of Akt* , 2003, Journal of Biological Chemistry.
[47] C. Sugimoto,et al. PI3K/Akt and apoptosis: size matters , 2003, Oncogene.
[48] R. Mulligan,et al. Isolation and Transplantation of Autologous Circulating Endothelial Cells Into Denuded Vessels and Prosthetic Grafts: Implications for Cell-Based Vascular Therapy , 2003, Circulation.
[49] N. Kobayashi,et al. Celiprolol Activates eNOS Through the PI3K-Akt Pathway and Inhibits VCAM-1 Via NF-&kgr;B Induced by Oxidative Stress , 2003, Hypertension.
[50] K. Collins,et al. Telomere maintenance and disease , 2003, The Lancet.
[51] Pascal J. Goldschmidt-Clermont,et al. Aging, Progenitor Cell Exhaustion, and Atherosclerosis , 2003, Circulation.
[52] T. Jacks,et al. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry , 2003, Nature.
[53] R. Brandes,et al. Hydrogen Peroxide Triggers Nuclear Export of Telomerase Reverse Transcriptase via Src Kinase Family-Dependent Phosphorylation of Tyrosine 707 , 2003, Molecular and Cellular Biology.
[54] W. Hofmann,et al. HMG-CoA Reductase Inhibitors Reduce Senescence and Increase Proliferation of Endothelial Progenitor Cells via Regulation of Cell Cycle Regulatory Genes , 2003, Circulation research.
[55] Arshed A. Quyyumi,et al. Circulating Endothelial Progenitor Cells, Vascular Function, and Cardiovascular Risk , 2003 .
[56] Goberdhan P Dimri,et al. Control of the Replicative Life Span of Human Fibroblasts by p16 and the Polycomb Protein Bmi-1 , 2003, Molecular and Cellular Biology.
[57] J. Isner,et al. Constitutive Human Telomerase Reverse Transcriptase Expression Enhances Regenerative Properties of Endothelial Progenitor Cells , 2002, Circulation.
[58] K. Shimada,et al. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial , 2002, The Lancet.
[59] W. Hahn,et al. A Two-Stage, p16INK4A- and p53-Dependent Keratinocyte Senescence Mechanism That Limits Replicative Potential Independent of Telomere Status , 2002, Molecular and Cellular Biology.
[60] J. Isner,et al. Statin Therapy Accelerates Reendothelialization: A Novel Effect Involving Mobilization and Incorporation of Bone Marrow-Derived Endothelial Progenitor Cells , 2002, Circulation.
[61] K. Chayama,et al. Endothelial function and oxidative stress in renovascular hypertension. , 2002, The New England journal of medicine.
[62] G. Peters,et al. INK4a‐deficient human diploid fibroblasts are resistant to RAS‐induced senescence , 2002, The EMBO journal.
[63] M. Makuuchi,et al. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis , 2002, Nature Medicine.
[64] A. Lloyd,et al. Milestones in cell division: Cell senescence and cancer , 2001, Nature Reviews Cancer.
[65] T. Meinertz,et al. Endothelial Dysfunction, Oxidative Stress, and Risk of Cardiovascular Events in Patients With Coronary Artery Disease , 2001, Circulation.
[66] D. Carrasco,et al. Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis , 2001, Nature.
[67] S. Fichtlscherer,et al. Number and Migratory Activity of Circulating Endothelial Progenitor Cells Inversely Correlate With Risk Factors for Coronary Artery Disease , 2001, Circulation research.
[68] F. Perticone,et al. Prognostic Significance of Endothelial Dysfunction in Hypertensive Patients , 2001, Circulation.
[69] A. Zeiher,et al. Pro‐atherogenic factors induce telomerase inactivation in endothelial cells through an Akt‐dependent mechanism , 2001, FEBS letters.
[70] J. Shay,et al. Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. , 2001, Genes & development.
[71] D. Harrison,et al. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. , 2000, Circulation research.
[72] S. Elledge,et al. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. , 2000, Genes & development.
[73] I. Sayek,et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. , 2000, Clinical biochemistry.
[74] J. Slingerland,et al. p16INK4A mediates cyclin dependent kinase 4 and 6 inhibition in senescent prostatic epithelial cells. , 2000, Cancer research.
[75] J. Isner,et al. Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[76] Hiroshi Takahashi,et al. Enhanced inhibition of hepatitis B virus production by asialoglycoprotein receptor-directed interferon , 1999, Nature Medicine.
[77] Haruchika Masuda,et al. Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization , 1999, Nature Medicine.
[78] R. DePinho,et al. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus , 1999, Nature.
[79] R. Ross,et al. Atherosclerosis is an inflammatory disease. , 1998, American heart journal.
[80] T. Kiyono,et al. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells , 1998, Nature.
[81] E. Hiyama,et al. Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress. , 1998, Life sciences.
[82] R. Schmieder,et al. Increased bioavailability of nitric oxide after lipid-lowering therapy in hypercholesterolemic patients: a randomized, placebo-controlled, double-blind study. , 1998, Circulation.
[83] R. DePinho,et al. Essential role of mouse telomerase in highly proliferative organs , 1998, Nature.
[84] C. Harley,et al. Extension of life-span by introduction of telomerase into normal human cells. , 1998, Science.
[85] C. D. Edwards,et al. p16INK4A Participates in a G1 Arrest Checkpoint in Response to DNA Damage , 1998, Molecular and Cellular Biology.
[86] D. Green,et al. Improvement in endothelial function by angiotensin converting enzyme inhibition in insulin-dependent diabetes mellitus. , 1997, The Journal of clinical investigation.
[87] M. Mandal,et al. Cell cycle-dependent modulation of telomerase activity in tumor cells. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[88] J. Yodoi,et al. Persistent oxidative stress in cancer , 1995, FEBS letters.
[89] C. Harley,et al. Telomeres shorten during ageing of human fibroblasts , 1990, Nature.
[90] R. Ross,et al. The pathogenesis of atherosclerosis (first of two parts). , 1976, The New England journal of medicine.