Maternal nutrition and pregnancy outcome
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Editor,—Symonds et al raise interesting issues about the potential use of animal models in examining the impact of nutrition during pregnancy on future risk of adult disease.1 However, their discussion of recent epidemiological research in humans includes several important factual inaccuracies. The authors imply that our analyses and those of Godfrey et al grouped women into categories of energy intake, and suggest that different results might have been obtained had “all the raw data points [been used] to determine potential relations …
[1] H. Budge,et al. Limitations of models used to examine the influence of nutrition during pregnancy and adult disease , 2000, Archives of disease in childhood.
[2] P. Yudkin,et al. Influence of maternal nutrition on outcome of pregnancy: prospective cohort study , 1999, BMJ.
[3] C Osmond,et al. Maternal nutrition in early and late pregnancy in relation to placental and fetal growth , 1996, BMJ.