A case of metastatic gallbladder tumor of the hepatocellular carcinoma

症例は49歳男性.B型慢性肝炎にて他院通院中,高度脈管浸潤を伴う多発肝細胞癌を認めたため,インターフェロン併用動注化学療法を施行したところ,奏効し,外来通院していた.経過観察中に施行した腹部CTにて胆嚢内にポリープ状の腫瘤を認めたため,当科に入院した.各種画像検査の結果,胆嚢ポリープと診断したが,胆嚢癌の可能性も考えられたため,開腹下胆嚢摘出術を施行した.病理組織では腫瘍細胞が索状や胞巣形成性に増生し,胆嚢腫瘍基部のリンパ管および静脈に腫瘍の浸潤を認め,化学療法前の腫瘍生検組織と類似しており,肝細胞癌の胆嚢転移再発と診断した.肝細胞癌の胆嚢転移はこれまでにほとんど報告がなく,きわめてまれであると考えられ報告した.

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