Calcium-dependent physiologic and pathologic stimulus-metabolic response coupling in hepatocytes.

[1]  A. Wiederkehr,et al.  Dynamic measurements of mitochondrial hydrogen peroxide concentration and glutathione redox state in rat pancreatic β-cells using ratiometric fluorescent proteins: confounding effects of pH with HyPer but not roGFP1. , 2012, The Biochemical journal.

[2]  Hong Wang,et al.  Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria[S] , 2011, Journal of Lipid Research.

[3]  D. Brasaemle,et al.  Packaging of Fat: An Evolving Model of Lipid Droplet Assembly and Expansion* , 2011, The Journal of Biological Chemistry.

[4]  Yongxin Zhao,et al.  An Expanded Palette of Genetically Encoded Ca2+ Indicators , 2011, Science.

[5]  T. Finkel.  Signal Transduction by Mitochondrial Oxidants* , 2011, The Journal of Biological Chemistry.

[6]  T. Finkel,et al.  Signal transduction by reactive oxygen species , 2011, The Journal of cell biology.

[7]  M. Stepanova,et al.  Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008. , 2011, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[8]  Takeharu Nagai,et al.  Ca²⁺ regulation of mitochondrial ATP synthesis visualized at the single cell level. , 2011, ACS chemical biology.

[9]  M. McNiven,et al.  Alcohol and lipid traffic don't mix , 2011, Hepatology.

[10]  P. Rorsman,et al.  Mitochondrial matrix pH controls oxidative phosphorylation and metabolism‐secretion coupling in INS‐1E clonal β cells , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[11]  R. Hamanaka,et al.  Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes. , 2010, TIBS -Trends in Biochemical Sciences. Regular ed.

[12]  M. Birnbaum,et al.  Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria , 2010, Cell.

[13]  G. Rutter,et al.  Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells. , 2010, Gastroenterology.

[14]  L. Gaspers,et al.  Uncoupling Protein-2 Modulates Myocardial Excitation–Contraction Coupling , 2010, Circulation research.

[15]  Dae-Yeul Yu,et al.  Inactivation of Peroxiredoxin I by Phosphorylation Allows Localized H2O2 Accumulation for Cell Signaling , 2010, Cell.

[16]  R. Denton,et al.  Regulation of mitochondrial dehydrogenases by calcium ions. , 2009, Biochimica et biophysica acta.

[17]  Takeharu Nagai,et al.  Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators , 2009, Proceedings of the National Academy of Sciences.

[18]  R. Parton,et al.  Lipid droplet-organelle interactions; sharing the fats. , 2009, Biochimica et biophysica acta.

[19]  S. Erickson.  Nonalcoholic fatty liver disease The author's work is supported by a Merit Award from the Department of Veterans Affairs and by DK-072187 from the National Institutes of Health. Published, JLR Papers in Press, December 12, 2008. , 2009, Journal of Lipid Research.

[20]  Robert V Farese,et al.  Lipid droplets at a glance , 2009, Journal of Cell Science.

[21]  T. Pozzan,et al.  Matrix alkalinization: a novel mitochondrial signal for sustained pancreatic β‐cell activation , 2009, The EMBO journal.

[22]  Michael P. Murphy,et al.  How mitochondria produce reactive oxygen species , 2008, The Biochemical journal.

[23]  L. Gaspers,et al.  Calcium-dependent activation of mitochondrial metabolism in mammalian cells. , 2008, Methods.

[24]  N. Sattar,et al.  Non-alcoholic fatty liver disease: an overview of prevalence, diagnosis, pathogenesis and treatment considerations. , 2008, Clinical science.

[25]  M. Mattson,et al.  Superoxide Flashes in Single Mitochondria , 2008, Cell.

[26]  A. Cederbaum,et al.  CYP2E1 and oxidative liver injury by alcohol. , 2008, Free radical biology & medicine.

[27]  P. Várnai,et al.  c-Met Must Translocate to the Nucleus to Initiate Calcium Signals*♦ , 2008, Journal of Biological Chemistry.

[28]  S. Sakaguchi,et al.  Common pathogenic mechanism in development progression of liver injury caused by non-alcoholic or alcoholic steatohepatitis. , 2007, The Journal of toxicological sciences.

[29]  T. Tordjmann,et al.  Rat hepatocytes express functional P2X receptors , 2007, FEBS letters.

[30]  A. Cederbaum,et al.  Induction of cytochrome promotes liver injury in ob/ob mice , 2007 .

[31]  J. Dranoff,et al.  The Spatial Distribution of Inositol 1,4,5-Trisphosphate Receptor Isoforms Shapes Ca2+ Waves* , 2007, Journal of Biological Chemistry.

[32]  H. Robenek,et al.  Adipophilin-enriched domains in the ER membrane are sites of lipid droplet biogenesis , 2006, Journal of Cell Science.

[33]  G. Rutter,et al.  ATP Regulation in Adult Rat Cardiomyocytes , 2006, Journal of Biological Chemistry.

[34]  D. A. Gomes,et al.  Calcium signaling in the nucleus. , 2006, Canadian journal of physiology and pharmacology.

[35]  Thomas Höfer,et al.  Models of IP3 and Ca2+ oscillations: frequency encoding and identification of underlying feedbacks. , 2006, Biophysical journal.

[36]  S. Lukyanov,et al.  Genetically encoded fluorescent indicator for intracellular hydrogen peroxide , 2006, Nature Methods.

[37]  L. Gaspers,et al.  Calcium signaling in liver. , 2005, Cell calcium.

[38]  Michael Karin,et al.  Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases , 2005, Cell.

[39]  A. A. Starkov,et al.  Mitochondrial metabolism of reactive oxygen species , 2005, Biochemistry (Moscow).

[40]  P. Brookes,et al.  Calcium, ATP, and ROS: a mitochondrial love-hate triangle. , 2004, American journal of physiology. Cell physiology.

[41]  Tullio Pozzan,et al.  Mitochondrial pH Monitored by a New Engineered Green Fluorescent Protein Mutant* , 2004, Journal of Biological Chemistry.

[42]  Michael P. Myers,et al.  Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate , 2003, Nature.

[43]  Clifford Goodman,et al.  The burden of selected digestive diseases in the United States. , 2002, Gastroenterology.

[44]  J. Dranoff,et al.  The type II inositol 1,4,5-trisphosphate receptor can trigger Ca2+ waves in rat hepatocytes. , 2002, Gastroenterology.

[45]  Toshiyuki Fukada,et al.  Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. , 2002, Molecular cell.

[46]  O. Gerasimenko,et al.  Calcium signalling in and around the nuclear envelope. , 2001, Biochemical Society transactions.

[47]  H. Tilg,et al.  Cytokines in alcoholic and nonalcoholic steatohepatitis. , 2000, The New England journal of medicine.

[48]  C. Dixon,et al.  Evidence that rat hepatocytes co‐express functional P2Y1 and P2Y2 receptors , 2000, British journal of pharmacology.

[49]  C. Wollheim,et al.  Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis , 1999, Nature.

[50]  G. Rutter,et al.  Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[51]  S. Patel,et al.  Molecular properties of inositol 1,4,5-trisphosphate receptors. , 1999, Cell calcium.

[52]  N. Chandel,et al.  Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[53]  G. Rutter,et al.  Integrating cytosolic calcium signals into mitochondrial metabolic responses , 1998, The EMBO journal.

[54]  G. Rutter,et al.  Coupling between cytosolic and mitochondrial calcium oscillations: role in the regulation of hepatic metabolism. , 1998, Biochimica et biophysica acta.

[55]  S. Rhee,et al.  Reversible Inactivation of Protein-tyrosine Phosphatase 1B in A431 Cells Stimulated with Epidermal Growth Factor* , 1998, The Journal of Biological Chemistry.

[56]  V. Skulachev,et al.  High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria , 1997, FEBS letters.

[57]  V. Mildažienė,et al.  Dependence of H2O2 Formation by Rat Heart Mitochondria on Substrate Availability and Donor Age , 1997, Journal of bioenergetics and biomembranes.

[58]  E. Tekle,et al.  Epidermal Growth Factor (EGF)-induced Generation of Hydrogen Peroxide , 1997, The Journal of Biological Chemistry.

[59]  T. Pozzan,et al.  A Role for Calcium Influx in the Regulation of Mitochondrial Calcium in Endothelial Cells (*) , 1996, The Journal of Biological Chemistry.

[60]  V. Ferrans,et al.  Requirement for Generation of H2O2 for Platelet-Derived Growth Factor Signal Transduction , 1995, Science.

[61]  György Hajnóczky,et al.  Decoding of cytosolic calcium oscillations in the mitochondria , 1995, Cell.

[62]  A P Thomas,et al.  Coordination of Ca2+ Signaling by Intercellular Propagation of Ca2+ Waves in the Intact Liver (*) , 1995, The Journal of Biological Chemistry.

[63]  V. Teplova,et al.  Inhibition by Ca2+ of the hydrolysis and the synthesis of ATP in Ehrlich ascites tumour mitochondria: relation to the Crabtree effect. , 1995, Biochimica et biophysica acta.

[64]  C. Wollheim,et al.  Dynamic pacing of cell metabolism by intracellular Ca2+ transients. , 1994, The Journal of biological chemistry.

[65]  F S Fay,et al.  Imaging in five dimensions: time-dependent membrane potentials in individual mitochondria. , 1993, Biophysical journal.

[66]  T. Pozzan,et al.  Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria. , 1993, Science.

[67]  M. Berridge.  Inositol trisphosphate and calcium signalling , 1993, Nature.

[68]  A. Thomas,et al.  Oscillatory cytosolic calcium waves independent of stimulated inositol 1,4,5-trisphosphate formation in hepatocytes. , 1991, The Journal of biological chemistry.

[69]  J. A. Thomas,et al.  Continuous measurement of mitochondrial pH gradients in isolated hepatocytes by difference ratio spectroscopy. , 1991, Archives of biochemistry and biophysics.

[70]  K. Ishak,et al.  Alcoholic liver disease: pathologic, pathogenetic and clinical aspects. , 1991, Alcoholism, clinical and experimental research.

[71]  G. Brown,et al.  Control of respiration and oxidative phosphorylation in isolated rat liver cells. , 1990, European journal of biochemistry.

[72]  J. Mccormack,et al.  Role of calcium ions in regulation of mammalian intramitochondrial metabolism. , 1990, Physiological reviews.

[73]  E J Sass,et al.  Characterization of cytosolic calcium oscillations induced by phenylephrine and vasopressin in single fura-2-loaded hepatocytes. , 1989, The Journal of biological chemistry.

[74]  A. Koretsky,et al.  Changes in pyridine nucleotide levels alter oxygen consumption and extra-mitochondrial phosphates in isolated mitochondria: a 31P-NMR and NAD(P)H fluorescence study. , 1987, Biochimica et biophysica acta.

[75]  David G. Nicholls,et al.  Bioenergetics an Introduction to the Chemiosmotic Theory , 1982 .

[76]  B Chance,et al.  Hydroperoxide metabolism in mammalian organs. , 1979, Physiological reviews.

[77]  B Chance,et al.  The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. , 1973, The Biochemical journal.

[78]  M. Berridge,et al.  Inositol Trisphosphate and Calcium Signaling , 2013 .

[79]  G. Farrell,et al.  LIVER FAILURE AND LIVER DISEASE Nonalcoholic Fatty Liver Disease: From Steatosis to Cirrhosis , 2006 .

[80]  S. Rhee,et al.  Regulation of phosphoinositide-specific phospholipase C. , 2001, Annual review of biochemistry.

[81]  Nathanson Mh,et al.  Calcium signaling mechanisms in liver in health and disease. , 1996 .

[82]  L. Hunyady,et al.  Pyridine nucleotide redox state parallels production of aldosterone in potassium-stimulated adrenal glomerulosa cells. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[83]  C. Lieber,et al.  Liquid diet technique of ethanol administration: 1989 update. , 1989, Alcohol and alcoholism.