Nonlinear dynamics and strange attractors in the biological system

This paper deals with the nonlinear dynamics of the biological system modeled by the multi-limit cycles Van der Pol oscillator. Both the autonomous and non-autonomous cases are considered using the analytical and numerical methods. In the autonomous state, the model displays phenomenon of birhythmicity while the harmonic oscillations with their corresponding stability boundaries are tackled in the non-autonomous case. Conditions under which superharmonic, subharmonic and chaotic oscillations occur in the model are also investigated. The analytical results are validated and supplemented by the results of numerical simulations.

[1]  A. Goldbeter,et al.  From simple to complex oscillatory behavior in metabolic and genetic control networks. , 2001, Chaos.

[2]  Stefano Lenci,et al.  Optimal numerical control of single-well to cross-well chaos transition in mechanical systems , 2003 .

[3]  R. Ruthen Adapting to Complexity , 1993 .

[4]  M. Lakshmanan,et al.  Bifurcation and chaos in the double-well Duffing–van der Pol oscillator: Numerical and analytical studies , 1997, chao-dyn/9709013.

[5]  Scott Barton Chaos, self-organization, and psychology. , 1994 .

[6]  K. H. Illinger,et al.  Biological effects of nonionizing radiation , 1981 .

[7]  A Garfinkel,et al.  Controlling cardiac chaos. , 1992, Science.

[8]  P. Holmes,et al.  Nonlinear Oscillations, Dynamical Systems, and Bifurcations of Vector Fields , 1983, Applied Mathematical Sciences.

[9]  Willi-Hans Steeb,et al.  Chaos in limit cycle systems with external periodic excitations , 1987 .

[10]  W. Ditto,et al.  Controlling chaos in the brain , 1994, Nature.

[11]  Fr. Kaiser Coherent Oscillations in Biological Systems I , 1978 .

[12]  Chi-Sang Poon,et al.  Decrease of cardiac chaos in congestive heart failure , 1997, Nature.

[13]  A. Goldbeter,et al.  Biochemical Oscillations And Cellular Rhythms: Contents , 1996 .

[14]  P. Hagedorn Non-Linear Oscillations , 1982 .

[15]  F. Kaiser,et al.  BIFURCATION STRUCTURE OF A DRIVEN, MULTI-LIMIT-CYCLE VAN DER POL OSCILLATOR (I): THE SUPERHARMONIC RESONANCE STRUCTURE , 1991 .

[16]  Hilaire Bertrand Fotsin,et al.  Behavior of the Van der Pol oscillator with two external periodic forces , 1997 .

[17]  F. Kaiser The Role of Chaos in Biological Systems , 1987 .

[18]  F. Kaiser Coherent oscillations in biological systems: Interaction with extremely low frequency fields , 1982 .

[19]  F. Kaiser,et al.  BIFURCATION STRUCTURE OF A DRIVEN MULTI-LIMIT-CYCLE VAN DER POL OSCILLATOR (II): SYMMETRY-BREAKING CRISIS AND INTERMITTENCY , 1991 .

[20]  Energy transfer dynamics. , 1987 .

[21]  H. Abarbanel,et al.  The role of chaos in neural systems , 1998, Neuroscience.

[22]  鈴木 増雄 A. H. Nayfeh and D. T. Mook: Nonlinear Oscillations, John Wiley, New York and Chichester, 1979, xiv+704ページ, 23.5×16.5cm, 10,150円. , 1980 .

[23]  C. Hayashi,et al.  Nonlinear oscillations in physical systems , 1987 .

[24]  A Goldbeter,et al.  Birhythmicity, chaos, and other patterns of temporal self-organization in a multiply regulated biochemical system. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[25]  Parlitz,et al.  Period-doubling cascades and devil's staircases of the driven van der Pol oscillator. , 1987, Physical review. A, General physics.

[26]  F. Kaiser Theory of Resonant Effects of RF and MW Energy , 1983 .

[27]  Pol D. Spanos,et al.  Non-Linear Oscillations, 2nd ed. , 1990 .