Inhibition of 8-oxoguanine DNA glycosylase (OGG1) expression suppresses polycystic ovarian syndrome via the NF-κB signaling pathway.
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[1] Jing Yang,et al. The abnormal level of HSP70 is related to Treg/Th17 imbalance in PCOS patients , 2021, Journal of Ovarian Research.
[2] Jing Yang,et al. Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN. , 2021, Archives of biochemistry and biophysics.
[3] Du Feng,et al. The Release of Peripheral Immune Inflammatory Cytokines Promote an Inflammatory Cascade in PCOS Patients via Altering the Follicular Microenvironment , 2021, Frontiers in Immunology.
[4] Yi Zhang,et al. C1QTNF6 participates in the pathogenesis of PCOS by affecting the inflammatory response of granulosa cells , 2021, Biology of Reproduction.
[5] Shushen Lin,et al. Cirsilineol attenuates LPS‐induced inflammation in both in vivo and in vitro models via inhibiting TLR‐4/NFkB/IKK signaling pathway , 2021, Journal of biochemical and molecular toxicology.
[6] T. Helleday,et al. NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487 , 2021, International journal of molecular sciences.
[7] J. Hoek,et al. The Mitochondrial Permeability Transition: Nexus of Aging, Disease and Longevity , 2020, Cells.
[8] J. Benítez,et al. Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects , 2020, Scientific Reports.
[9] M. Qorbani,et al. The Effect of Oligopin Supplementation on Hormonal and Metabolic Profiles in the Polycystic Ovary Syndrome: A Randomized Controlled Trial , 2020, Frontiers in Endocrinology.
[10] Zhigang Guo,et al. Impairment of Pol β-related DNA base-excision repair leads to ovarian aging in mice , 2020, Aging.
[11] J. Benítez,et al. Targeting OGG1 arrests cancer cell proliferation by inducing replication stress , 2020, Nucleic acids research.
[12] Jun Zhang,et al. Risk of Cardiovascular and Cerebrovascular Events in Polycystic Ovarian Syndrome Women: A Meta-Analysis of Cohort Studies , 2020, Frontiers in Cardiovascular Medicine.
[13] Xin-Mei Liu,et al. Novel PGK1 determines SKP2-dependent AR stability and reprograms granular cell glucose metabolism facilitating ovulation dysfunction , 2020, EBioMedicine.
[14] Xia Li,et al. DNA repair enzyme OGG1 promotes alveolar progenitor cell renewal and relieves PM2.5-induced lung injury and fibrosis. , 2020, Ecotoxicology and environmental safety.
[15] P. Fan,et al. Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome , 2020, Reproductive Biology and Endocrinology.
[16] P. Hardiman,et al. Molecular mechanisms underlying altered neurobehavioural development of female offspring of mothers with polycystic ovary syndrome: FOS-mediated regulation of neurotrophins in placenta , 2020, EBioMedicine.
[17] Aifen Zhou,et al. CircPSMC3 alleviates the symptoms of PCOS by sponging miR‐296‐3p and regulating PTEN expression , 2020, Journal of cellular and molecular medicine.
[18] I. Cho,et al. Therapeutic Effects and Mechanisms of Herbal Medicines for Treating Polycystic Ovary Syndrome: A Review , 2020, Frontiers in Pharmacology.
[19] Xinming Yang,et al. Electroacupuncture alleviates polycystic ovary syndrome-like symptoms through improving insulin resistance, mitochondrial dysfunction, and endoplasmic reticulum stress via enhancing autophagy in rats , 2020, Molecular medicine.
[20] S. Ebrahimpour,et al. Pathophysiological roles of chronic low‐grade inflammation mediators in polycystic ovary syndrome , 2020, Journal of cellular physiology.
[21] Jing Yang,et al. Chromosomal polymorphisms associated with reproductive outcomes after IVF-ET , 2020, Journal of Assisted Reproduction and Genetics.
[22] S. Haggarty,et al. HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease , 2020, Nature Communications.
[23] Xiaofeng Yang,et al. Vitamin D Deficiency Is Associated With Metabolic Risk Factors in Women With Polycystic Ovary Syndrome: A Cross-Sectional Study in Shaanxi China , 2020, Frontiers in Endocrinology.
[24] M. Selman,et al. Mitochondrial 8-Oxoguanine DNA Glycosylase Mitigates Alveolar Epithelial Cell PINK1 Deficiency, Mitochondrial DNA Damage, Apoptosis and Lung Fibrosis. , 2020, American journal of physiology. Lung cellular and molecular physiology.
[25] M. Kunicki,et al. Inflammatory Markers in Women with Polycystic Ovary Syndrome , 2020, BioMed research international.
[26] Wei Li,et al. Berberine increases glucose uptake and intracellular ROS levels by promoting Sirtuin 3 ubiquitination. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[27] Yi-Xun Liu,et al. Melatonin Reduces Androgen Production and Upregulates Heme Oxygenase-1 Expression in Granulosa Cells from PCOS Patients with Hypoestrogenia and Hyperandrogenia , 2019, Oxidative medicine and cellular longevity.
[28] B. D’Onofrio,et al. Maternal polycystic ovary syndrome and risk of neuropsychiatric disorders in offspring: prenatal androgen exposure or genetic confounding? , 2019, Psychological Medicine.
[29] Simon C Watkins,et al. Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. , 2019, Molecular cell.
[30] V. Zoumpourlis,et al. Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer , 2019, Pharmacology & therapeutics.
[31] P. Artursson,et al. Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation , 2018, Science.
[32] T. Helleday,et al. Targeting BER enzymes in cancer therapy. , 2018, DNA repair.
[33] Seema Patel. Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy , 2018, The Journal of Steroid Biochemistry and Molecular Biology.
[34] M. Brännström,et al. Endometrial progesterone receptor isoforms in women with polycystic ovary syndrome. , 2018, American journal of translational research.
[35] J. Gosalvez,et al. Impact of polymorphism in DNA repair genes OGG1 and XRCC1 on seminal parameters and human male infertility , 2018, Andrologia.
[36] Jing Sun,et al. Functional Characterization of MicroRNA-27a-3p Expression in Human Polycystic Ovary Syndrome , 2018, Endocrinology.
[37] W. Xiang,et al. Oxidative stress in granulosa cells contributes to poor oocyte quality and IVF-ET outcomes in women with polycystic ovary syndrome , 2018, Frontiers of Medicine.
[38] I. Boldogh,et al. The Role of 8-Oxoguanine DNA Glycosylase-1 in Inflammation , 2014, International journal of molecular sciences.
[39] C. Hao,et al. RUNX2, GPX3 and PTX3 gene expression profiling in cumulus cells are reflective oocyte/embryo competence and potentially reliable predictors of embryo developmental competence in PCOS patients , 2013, Reproductive Biology and Endocrinology.
[40] Xuenong Zhang,et al. Ethanol extract of Adiantum capillus-veneris L. suppresses the production of inflammatory mediators by inhibiting NF-κB activation. , 2013, Journal of ethnopharmacology.
[41] F. González. Inflammation in Polycystic Ovary Syndrome: Underpinning of insulin resistance and ovarian dysfunction , 2012, Steroids.
[42] R. Azziz,et al. Abnormal expression of genes involved in inflammation, lipid metabolism, and Wnt signaling in the adipose tissue of polycystic ovary syndrome. , 2012, The Journal of clinical endocrinology and metabolism.
[43] Ricardo Azziz,et al. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis , 2011, Nature Reviews Endocrinology.
[44] F. Tsai,et al. Association of the C-285T and A5954G polymorphisms in the DNA repair gene OGG1 with the susceptibility of rheumatoid arthritis , 2012, Rheumatology International.
[45] H. Abboud,et al. Mechanism of Oxidative DNA Damage in Diabetes , 2008, Diabetes.
[46] A. Labigne,et al. Deficiency in OGG1 Protects against Inflammation and Mutagenic Effects Associated with H. pylori Infection in Mouse , 2006, Helicobacter.
[47] C. Szabó,et al. Potential role for 8‐oxoguanine DNA glycosylase in regulating inflammation , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[48] B. Fauser,et al. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). , 2004, Human reproduction.
[49] H. Aburatani,et al. Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[50] T. Lindahl,et al. Repair of endogenous DNA damage. , 2000, Cold Spring Harbor symposia on quantitative biology.
[51] E. Seeberg,et al. Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. , 1999, Proceedings of the National Academy of Sciences of the United States of America.