Predictors of Persistent Axial Neck Pain After Cervical Laminoplasty

Study Design. Retrospective analysis of prospective data. Objective. The aim of this study was to reveal baseline predictors of persistent postlaminoplasty neck pain. Summary of Background Data. Axial neck pain is one of the most common complications after cervical laminoplasty; however, baseline predictors of persistent postlaminoplasty neck pain are unclear. Methods. We analyzed data from 156 patients who completed a 2-year follow-up after double-door laminoplasty for degenerative cervical myelopathy. Patients rated the average intensity of axial neck pain in the last month using an 11-point numerical rating scale preoperatively and at the 2-year follow-up. The dependent variable was the presence of moderate-to-severe neck pain (numerical rating scale ≥4) at the 2-year follow-up. The independent variables included patient characteristics, baseline radiological parameters, surgical variables, baseline axial neck pain intensity, and baseline functions, which were measured by the Japanese Orthopaedic Association score and the Short Form-36 survey (SF-36). Logistic regression analysis was performed to identify independent predictors of moderate-to-severe neck pain after laminoplasty. Results. At the 2-year follow-up, 51 patients (32%) had moderate-to-severe neck pain, and 106 patients (68%) had no or mild pain. Univariate analysis revealed that the ratio of cervical anterolisthesis, ratio of current smoking, baseline neck pain intensity, and baseline SF-36 Mental Component Summary differed significantly between the groups. Multivariate logistic regression analysis showed that independent predictors of moderate-to-severe neck pain at the 2-year follow-up include the presence of anterolisthesis, current smoking, moderate-to-severe baseline neck pain, and lower SF-36 Mental Component Summary. The presence of anterolisthesis and moderate-to-severe baseline neck pain were also associated with significantly poorer physical function after surgery. Conclusion. The presence of anterolisthesis was associated not only with the highest odds ratio of persistent neck pain but also with significantly poorer functional outcomes. Indications for cervical laminoplasty should be carefully determined in patients with cervical anterolisthesis. Level of Evidence: 4

[1]  H. Terai,et al.  Clinical Outcome of Cervical Laminoplasty and Postoperative Radiological Change for Cervical Myelopathy With Degenerative Spondylolisthesis , 2016, Spine.

[2]  A. Boonstra,et al.  Cut-Off Points for Mild, Moderate, and Severe Pain on the Numeric Rating Scale for Pain in Patients with Chronic Musculoskeletal Pain: Variability and Influence of Sex and Catastrophizing , 2016, Front. Psychol..

[3]  S. Glassman,et al.  Can the anxiety domain of EQ-5D and mental health items from SF-36 help predict outcomes after surgery for lumbar degenerative disorders? , 2016, Journal of neurosurgery. Spine.

[4]  Sakae Tanaka,et al.  Cervical Anterolisthesis: A Predictor of Poor Neurological Outcomes in Cervical Spondylotic Myelopathy Patients After Cervical Laminoplasty , 2016, Spine.

[5]  K. Takeshita,et al.  Impact of Axial Neck Pain on Quality of Life After Laminoplasty , 2015, Spine.

[6]  M. Fehlings,et al.  Degenerative Cervical Myelopathy: Epidemiology, Genetics, and Pathogenesis , 2015, Spine.

[7]  Joseph S. Cheng,et al.  Outcomes after cervical laminectomy with instrumented fusion versus expansile laminoplasty: A propensity matched study of 3185 patients , 2015, Journal of Clinical Neuroscience.

[8]  Y. Yukawa,et al.  Comparative Effectiveness of Open-Door Laminoplasty Versus French-Door Laminoplasty in Cervical Compressive Myelopathy , 2014, Spine.

[9]  Zhilai Zhou,et al.  Anterior decompression and fusion versus posterior laminoplasty for multilevel cervical compressive myelopathy. , 2014, Orthopedics.

[10]  J. Dettori,et al.  Nonoperative Management of Cervical Myelopathy: A Systematic Review , 2013, Spine.

[11]  Christopher Wang,et al.  Prevalence and Motion Characteristics of Degenerative Cervical Spondylolisthesis in the Symptomatic Adult , 2013, Spine.

[12]  F. Jamali,et al.  Smoking and the risk of mortality and vascular and respiratory events in patients undergoing major surgery. , 2013, JAMA surgery.

[13]  Annie L. Raich,et al.  Neck Pain Following Cervical Laminoplasty: Does Preservation of the C2 Muscle Attachments and/or C7 Matter? , 2013, Evidence-Based Spine-Care Journal.

[14]  Yang Cao,et al.  The effect of cigarette smoke exposure on spinal cord injury in rats. , 2013, Journal of neurotrauma.

[15]  R. Chang,et al.  Cigarette Smoking Accelerated Brain Aging and Induced Pre-Alzheimer-Like Neuropathology in Rats , 2012, PloS one.

[16]  E. Mohammadi,et al.  Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[17]  C. Kalkman,et al.  Determination of moderate-to-severe postoperative pain on the numeric rating scale: a cut-off point analysis applying four different methods. , 2011, British journal of anaesthesia.

[18]  James D. Kang,et al.  Laminoplasty versus Laminectomy and Fusion for Multilevel Cervical Spondylotic Myelopathy , 2011, Clinical orthopaedics and related research.

[19]  Y. Hoshino,et al.  Long-term results of double-door laminoplasty using hydroxyapatite spacers in patients with compressive cervical myelopathy , 2011, European Spine Journal.

[20]  L. Dai,et al.  Degenerative cervical spondylolisthesis: a systematic review , 2011, International Orthopaedics.

[21]  Masato Tanaka,et al.  Erratum to: Degenerative spondylolisthesis does not influence surgical results of laminoplasty in elderly cervical spondylotic myelopathy patients , 2010, European Spine Journal.

[22]  H. Shigematsu Degenerative spondylolisthesis does not influence surgical results of laminoplasty in elderly cervical spondylotic myelopathy patients , 2010, European Spine Journal.

[23]  L. Kauppila Atherosclerosis and disc degeneration/low-back pain--a systematic review. , 2009, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[24]  Vikram Patel,et al.  Depression, chronic diseases, and decrements in health: results from the World Health Surveys , 2007, The Lancet.

[25]  R. Ploutz-Snyder,et al.  Emotional Health Predicts Pain and Function After Fusion: A Prospective Multicenter Study , 2006, Spine.

[26]  J. Woodring,et al.  The radiographic distinction of degenerative slippage (spondylolisthesis and retrolisthesis) from traumatic slippage of the cervical spine , 2004, Skeletal Radiology.

[27]  A. Peolsson,et al.  Predictive factors for the outcome of anterior cervical decompression and fusion , 2003, European Spine Journal.

[28]  S. Emery,et al.  Cervical Spondylotic Myelopathy: Diagnosis and Treatment , 2001, The Journal of the American Academy of Orthopaedic Surgeons.

[29]  S J Linton,et al.  A review of psychological risk factors in back and neck pain. , 2000, Spine.

[30]  John D. Davis,et al.  Outcome of patients treated for cervical myelopathy. A prospective, multicenter study with independent clinical review. , 2000, Spine.

[31]  N. Mayo,et al.  The association between cigarette smoking and back pain in adults. , 1999, Spine.

[32]  K. Yonenobu,et al.  Neck and Shoulder Pain After Laminoplasty: A Noticeable Complication , 1996, Spine.

[33]  I. Gastinger,et al.  [A prospective multicenter study of appendicitis treatment]. , 1991, Zentralblatt fur Chirurgie.