osteoclast-A rare location of benign osteoblastoma: case study and a review of the literature

. – Osteoblastoma is a solitary, benign bone tumor that is rarely localized in the frontal sinus. It consists of hypocellular mineralized tissue that may form large masses or irregular trabeculae. A 31 year old man came to our attention with a 7 month history of diplopia, photophobia, frontal headhaches and progressive exophthalmos with proptosis of the left eye. The patient was submitted to computed to-mography (CT) which allowed to appraise the extension of the lesion. The mass expanded inside the left frontal sinus and the upper ethmoidal cells invading the left orbital roof. Con-sidering the extension of the tumor, the site and the connections with contiguous structures, a combination of endoscopic endonasal technique with intraorbital approach was performed. At histological examination typical features of benign osteoblastoma were observed. The sites of predilection for the tumor are the long bones, vertebral column, and small bones of hands and feet. Its occurrence in the skull and jaw bones is relatively rare and represents only 15% of all osteoblastomas. To our knowledge, only 5 cases of osteoblastoma of the frontal sinus have been previously reported in the English-language literature. This report describes a case of benign osteoblastoma in a rare site, namely, the frontal sinus with particular attention about the differential diagnosis and the treatment.

[1]  M. Sillers,et al.  Common fibro-osseous lesions of the paranasal sinuses. , 2006, Otolaryngologic clinics of North America.

[2]  J. Szukalski,et al.  [Benign osteoblastoma of the frontal sinus]. , 2004, Otolaryngologia polska = The Polish otolaryngology.

[3]  L. Ackerman,et al.  Metastatic and pseudomalignant osteoblastoma: a report of two unusual cases , 2004, Skeletal Radiology.

[4]  D. Lucas Dahlin’s Bone Tumors: General Aspects and Data on 11,087 Cases , 1996 .

[5]  K. Devaney Dahlin's Bone Tumors. General Aspects and Data on 11,087 Cases , 1996 .

[6]  F. Frassica,et al.  Clinicopathologic features and treatment of osteoid osteoma and osteoblastoma in children and adolescents. , 1996, The Orthopedic clinics of North America.

[7]  F. Sim,et al.  Osteoblastoma: clinicopathologic study of 306 cases. , 1994, Human pathology.

[8]  M. Parodi,et al.  Partial ablation of benign osteoblastoma: a case report. , 1993, Metabolic, pediatric, and systemic ophthalmology.

[9]  R. Juniper,et al.  Osteoblastoma: a case report and description of the access used to the retromaxillary area. , 1991, The British journal of oral & maxillofacial surgery.

[10]  Weiss Sw,et al.  Borderline osteoblastic tumors: problems in the differential diagnosis of aggressive osteoblastoma and low-grade osteosarcoma. , 1984 .

[11]  A. Huvos Bone tumors, diagnosis, treatment, and prognosis , 1979 .

[12]  A. Cohn Bone tumors. , 1978, Orthopedics.

[13]  M. Markowska,et al.  [Benign osteoblastoma of the ethmoid labyrinth, frontal sinus and orbit]. , 1975, Klinika oczna.

[14]  L. Przybora,et al.  [Case of frontal sinus osteoblastoma]. , 1974, Otolaryngologia polska = The Polish otolaryngology.

[15]  N. Smith Benign osteoblastoma of the mandible: report of case. , 1972, Journal of oral surgery.

[16]  E. Vensi [Multiple benign osteoblastoma of the femur and frontal sinus]. , 1965, Annali di laringologia, otologia, rinologia, faringologia.

[17]  D. Dahlin,et al.  Giant osteoid osteoma. , 1954, The Journal of bone and joint surgery. American volume.

[18]  H. Jaffe,et al.  AN OSTEOBLASTIC OSTEOID TISSUE-FORMING TUMOR OF A METACARPAL BONE , 1932 .