Uveal Lymphoma Extranodal marginal zone B-cell lymphoma of the left eye with choroidal, episcleral, and orbital involvement

History of Present Illness: A 71-year-old man was referred to the University of Iowa Retina and Vitreous Clinic for evaluation for possible uveal lymphoma of the left eye. He was first seen locally for blurred vision in both eyes and was found to have subretinal fluid in the left eye. This was initially concerning for uveal effusion syndrome. Laboratory workup at that time with complete blood count, lyme titers, syphilis antibody testing, soluble IL-2 receptor, quantiferon gold, serum protein electrophoresis (SPEP), rheumatoid factor, and chest x-ray showed an elevated soluble IL-2 receptor but was otherwise unremarkable. He was subsequently lost to follow up for a period of about a year due to the COVID-19 pandemic. He then returned locally with worsening subretinal fluid and concern for a “salmon patch” lesion on the conjunctiva of the left eye.

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