De novo identification of VRC01 class HIV-1–neutralizing antibodies by next-generation sequencing of B-cell transcripts
暂无分享,去创建一个
Tongqing Zhou | Baoshan Zhang | James C Mullikin | Cinque S. Soto | John R Mascola | Lawrence Shapiro | Peter D Kwong | J. Mullikin | J. Mascola | J. Casazza | C. Soto | Baoshan Zhang | T. Zhou | K. Mckee | L. Shapiro | P. Kwong | S. O'dell | Jiang Zhu | Xueling Wu | Xueling Wu | Jiang Zhu | Sijy O'Dell | Krisha McKee | Cinque Soto | Joseph P Casazza | S. O’dell | Baoshan Zhang
[1] D. Mccormick. Sequence the Human Genome , 1986, Bio/Technology.
[2] George Georgiou,et al. High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire , 2013, Nature Biotechnology.
[3] Chaim A. Schramm,et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus , 2013, Nature.
[4] R. Fleischmann,et al. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. , 1995, Science.
[5] Mario Roederer,et al. Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing , 2011, Science.
[6] James E. Crowe,et al. Human Peripheral Blood Antibodies with Long HCDR3s Are Established Primarily at Original Recombination Using a Limited Subset of Germline Genes , 2012, PloS one.
[7] E. Mardis. Next-generation DNA sequencing methods. , 2008, Annual review of genomics and human genetics.
[8] Young Do Kwon,et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. , 2013, Immunity.
[9] P. Colman,et al. Structure of antibody-antigen complexes: implications for immune recognition. , 1988, Advances in immunology.
[10] R. Kolodny,et al. Protein structure comparison: implications for the nature of 'fold space', and structure and function prediction. , 2006, Current opinion in structural biology.
[11] P. Lipsky,et al. Characterization of the Human Ig Heavy Chain Antigen Binding Complementarity Determining Region 3 Using a Newly Developed Software Algorithm, JOINSOLVER , 2004, The Journal of Immunology.
[12] D. Dimitrov,et al. Expressed antibody repertoires in human cord blood cells: 454 sequencing and IMGT/HighV-QUEST analysis of germline gene usage, junctional diversity, and somatic mutations , 2011, Immunogenetics.
[13] Thomas B Kepler,et al. B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study , 2012, Nature Biotechnology.
[14] J. V. Moran,et al. Initial sequencing and analysis of the human genome. , 2001, Nature.
[15] Wayne A Hendrickson,et al. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[16] Baoshan Zhang,et al. Mining the antibodyome for HIV-1–neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains , 2013, Proceedings of the National Academy of Sciences.
[17] L. Stamatatos,et al. Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies , 2013, The Journal of experimental medicine.
[18] I. Wilson,et al. HIV-1 and influenza antibodies: seeing antigens in new ways , 2009, Nature Immunology.
[19] F. Sanger,et al. A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase. , 1975, Journal of molecular biology.
[20] J. Sodroski,et al. The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus , 2008, Nature Reviews Microbiology.
[21] G. Hon,et al. Next-generation genomics: an integrative approach , 2010, Nature Reviews Genetics.
[22] International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome , 2001, Nature.
[23] M. Hilleman. Overview of the Needs and Realities for Developing New and Improved Vaccines in the 21st Century , 2003, Intervirology.
[24] Young Do Kwon,et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 , 2011, Nature.
[25] Patrick Wilson,et al. iHMMune-align: hidden Markov model-based alignment and identification of germline genes in rearranged immunoglobulin gene sequences , 2007, Bioinform..
[26] Tongqing Zhou,et al. Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01 , 2010, Science.
[27] Nicolas Fischer. Sequencing antibody repertoires: the next generation. , 2011, mAbs.
[28] Ron Diskin,et al. Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120 , 2012, Proceedings of the National Academy of Sciences.
[29] Ron Diskin,et al. Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding , 2011, Science.
[30] Pham Phung,et al. Broad neutralization coverage of HIV by multiple highly potent antibodies , 2011, Nature.
[31] Hugo Y. K. Lam,et al. Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes , 2012, Cell.
[32] David Nemazee,et al. Rational immunogen design to target specific germline B cell receptors , 2012, Retrovirology.
[33] R. Contreras,et al. Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene , 1976, Nature.
[34] E. Mardis. The impact of next-generation sequencing technology on genetics. , 2008, Trends in genetics : TIG.
[35] Marie-Paule Lefranc,et al. IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis , 2008, Nucleic Acids Res..
[36] James E Crowe,et al. Epitope-Specific Human Influenza Antibody Repertoires Diversify by B Cell Intraclonal Sequence Divergence and Interclonal Convergence , 2011, The Journal of Immunology.
[37] J. Mascola,et al. Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies. , 2012, Immunity.
[38] Thomas B. Kepler,et al. SoDA2: a Hidden Markov Model approach for identification of immunoglobulin rearrangements , 2010, Bioinform..
[39] O. Schueler‐Furman,et al. Progress in Modeling of Protein Structures and Interactions , 2005, Science.
[40] W. Fiers,et al. Nucleotide Sequence of the Gene Coding for the Bacteriophage MS2 Coat Protein , 1972, Nature.
[41] E. Padlan,et al. Structural basis for the specificity of antibody–antigen reactions and structural mechanisms for the diversification of antigen-binding specificities , 1977, Quarterly Reviews of Biophysics.
[42] Gira Bhabha,et al. Antibody Recognition of a Highly Conserved Influenza Virus Epitope , 2009, Science.
[43] I. Wilson,et al. X-ray crystallographic analysis of free and antigen-complexed Fab fragments to investigate structural basis of immune recognition. , 1991, Methods in enzymology.
[44] Michel C Nussenzweig,et al. Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning. , 2008, Journal of immunological methods.
[45] Pham Phung,et al. Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target , 2009, Science.
[46] Seung Hyun Kang,et al. Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells , 2010, Nature Biotechnology.
[47] Tongqing Zhou,et al. Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization , 2013, Cell.
[48] J. Mullikin,et al. Somatic Populations of PGT135–137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics , 2012, Front. Microbio..
[49] Mario Roederer,et al. Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1 , 2010, Science.