Preserved antigenicity of HIV-1 p24 produced and purified in high yields from plants inoculated with a tobacco mosaic virus (TMV)-derived vector.

[1]  A. Siegel,et al.  The effect of tobacco mosaic virus infection on host and virus-specific protein synthesis in protoplasts. , 1978, Virology.

[2]  Patrick W. Lee,et al.  Purification and characterization of the reovirus cell attachment protein σ1 , 1987 .

[3]  E. Wimmer,et al.  Expression in Escherichia coli and purification of human immunodeficiency virus type 1 capsid protein (p24). , 1990, AIDS research and human retroviruses.

[4]  B. Walker,et al.  HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells and cloned effector cells. , 1991, Journal of immunology.

[5]  D. M. Lam,et al.  Expression of hepatitis B surface antigen in transgenic plants. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[6]  P. Rouger,et al.  p24 antigen and HIV screening , 1992, The Lancet.

[7]  C. Carter,et al.  Assembly of recombinant human immunodeficiency virus type 1 capsid protein in vitro , 1992, Journal of virology.

[8]  C. Carrillo,et al.  Recognition of B and T cell epitopes by cattle immunized with a synthetic peptide containing the major immunogenic site of VP1 FMDV 01 Campos. , 1994, Virology.

[9]  L. Babiuk,et al.  Immunological response to recombinant VP8* subunit protein of bovine roravirus in pregnant cattle. , 1995, The Journal of general virology.

[10]  H. Kräusslich,et al.  In vitro assembly properties of purified bacterially expressed capsid proteins of human immunodeficiency virus. , 1997, European journal of biochemistry.

[11]  J. Howard,et al.  Production of recombinant proteins in transgenic plants: Practical considerations , 1997, Biotechnology and bioengineering.

[12]  M. Uhlén,et al.  Affinity fusion strategies for detection, purification, and immobilization of recombinant proteins. , 1997, Protein expression and purification.

[13]  J. Johnson,et al.  Presentation of heterologous peptides on plant viruses: genetics, structure, and function. , 1997, Annual review of phytopathology.

[14]  H. Kräusslich,et al.  N-Terminal Extension of Human Immunodeficiency Virus Capsid Protein Converts the In Vitro Assembly Phenotype from Tubular to Spherical Particles , 1998, Journal of Virology.

[15]  C. Lacomme,et al.  Genetic Engineering and the Expression of Foreign Peptides or Proteins with Plant Virus-Based Vectors , 1998 .

[16]  P Boulanger,et al.  Morphopoietic determinants of HIV-1 Gag particles assembled in baculovirus-infected cells. , 1998, Virology.

[17]  C. Carrillo,et al.  Protection of mice against challenge with foot and mouth disease virus (FMDV) by immunization with foliar extracts from plants infected with recombinant tobacco mosaic virus expressing the FMDV structural protein VP1. , 1999, Virology.

[18]  H. Koprowski,et al.  Plant viral vectors based on tobamoviruses. , 1999, Current topics in microbiology and immunology.

[19]  R. Levy,et al.  Rapid production of specific vaccines for lymphoma by expression of the tumor-derived single-chain Fv epitopes in tobacco plants. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[20]  D. J. Lewandowski,et al.  Heterologous sequences greatly affect foreign gene expression in tobacco mosaic virus-based vectors. , 1999, Virology.

[21]  G. Stewart,et al.  Therapeutic vaccination with p24-VLP and zidovudine augments HIV-specific cytotoxic T lymphocyte activity in asymptomatic HIV-infected individuals. , 1999, AIDS research and human retroviruses.

[22]  Guichan Zhang,et al.  In planta expression of HIV-1 p24 protein using and RNA plant virus-based expression vector , 2000, Molecular biotechnology.

[23]  Gordon Allison,et al.  Transgenic plants as factories for biopharmaceuticals , 2000, Nature Biotechnology.

[24]  A. Walmsley,et al.  Plants for delivery of edible vaccines. , 2000, Current opinion in biotechnology.

[25]  W. Klaskala,et al.  Vertical transmission of Kaposi's sarcoma‐associated herpesvirus , 2001, International journal of cancer.

[26]  James G. Herndon,et al.  Control of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA/MVA Vaccine , 2001, Science.

[27]  B. Moss,et al.  Reduction of Simian-Human Immunodeficiency Virus 89.6P Viremia in Rhesus Monkeys by Recombinant Modified Vaccinia Virus Ankara Vaccination , 2001, Journal of Virology.

[28]  Henryk Mach,et al.  Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity , 2002, Nature.

[29]  T. Ndung’u,et al.  Magnitude and Frequency of Cytotoxic T-Lymphocyte Responses: Identification of Immunodominant Regions of Human Immunodeficiency Virus Type 1 Subtype C , 2002, Journal of Virology.

[30]  S. Garger,et al.  Making an ally from an enemy: plant virology and the new agriculture. , 2002, Annual review of phytopathology.

[31]  Sean Chapman,et al.  Improvement of the movement and host range properties of a plant virus vector through DNA shuffling. , 2002, The Plant journal : for cell and molecular biology.

[32]  K. White,et al.  Production of HIV-1 p24 protein in transgenic tobacco plants , 2002, Molecular biotechnology.

[33]  O. Taboga,et al.  Bovine herpes virus gD protein produced in plants using a recombinant tobacco mosaic virus (TMV) vector possesses authentic antigenicity. , 2003, Vaccine.

[34]  A. Walmsley,et al.  Plant cell factories and mucosal vaccines , 2003, Current Opinion in Biotechnology.

[35]  W. Klaskala,et al.  Postnatal human herpesvirus 8 and human immunodeficiency virus type 1 infection in mothers and infants from Zambia. , 2003, The Journal of infectious diseases.