Inverted Papilloma Invading the Orbit Through the Nasolacrimal Duct: A Case Report

Purpose: Inverted papillomas of the nose and paranasal sinuses are uncommon neoplasms, characterized by their tendency to recur and by their association with malignancy and invasive potential to the adjacent structures. The authors report a case of recurrent inverted papilloma of the nasal cavity and sinuses that eventually invaded the orbit through the nasolacrimal duct. Method: Assessment and management of a 47-year-old patient who presented with epiphora, left medial canthal area mass, proptosis and lateral displacement of his left eye associated with significant nasal obstruction. Results: Computed tomography and magnetic resonance imaging studies revealed a mass filling the nasal cavities and sinuses, invading the left orbit without destruction of any orbital walls. During excision of the tumor, it was learned that the orbital component of the tumor was connected with the sinonasal tumor through the nasolacrimal duct without any bony defects of the orbit. Histopathology of tumor proved to be inverted papilloma with areas of malignant transformation. Conclusion: Athough a rare cause of proptosis, inverted papilloma with orbital invasion must be considered in the differential diagnosis of nasosinus tumors invading the orbit. The case presented demonstrates that these tumors may invade the orbit through the nasolacrimal duct in the absence of orbital wall defects.

[1]  M. Bajaj,et al.  Inverted papilloma invading the orbit , 2002, Orbit.

[2]  J. Krouse Endoscopic treatment of inverted papilloma: safety and efficacy. , 2001, American journal of otolaryngology.

[3]  V. Lund,et al.  Optimum imaging for inverted papilloma , 2000, The Journal of Laryngology & Otology.

[4]  J. Krouse Development of a Staging System for Inverted Papilloma , 2000, The Laryngoscope.

[5]  E. Vural,et al.  Intracranial extension of inverted papilloma: An unusual and potentially fatal complication , 1999, Head & neck.

[6]  V. Elner,et al.  Inverted papillomas that invade the orbit. , 1995, Archives of ophthalmology.

[7]  R. Warren,et al.  Invasive transitional cell carcinoma of the lacrimal sac arising in an inverted papilloma. , 1994, Archives of ophthalmology.

[8]  A. W. Lawton,et al.  Proptosis from maxillary sinus inverted papilloma with malignant transformation. , 1986, Archives of ophthalmology.

[9]  Wesley Re,et al.  Proptosis and pseudocyst formation from inverted papilloma. , 1982 .

[10]  Z. Karcioglu,et al.  Proptosis and pseudocyst formation from inverted papilloma. , 1982, Annals of ophthalmology.

[11]  H. N. Margolin,et al.  Malignant inverted papilloma characterized by proptosis. , 1976, American journal of ophthalmology.

[12]  K. H. Perzin,et al.  Papillomatosis of nasal cavity and paranasal sinuses (inverted papilloma, squamous papilloma). A clinicopathologic study , 1972, Cancer.

[13]  J. Conley Sinus tumors invading the orbit. , 1966, Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology.