Gypenoside XVII inhibits ox-LDL-induced macrophage inflammatory responses and promotes cholesterol efflux through activating the miR-182-5P/HDAC9 signaling pathway.
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[1] Jun Shen,et al. miR-383-5p Regulated by the Transcription Factor CTCF Affects Neuronal Impairment in Cerebral Ischemia by Mediating Deacetylase HDAC9 Activity , 2022, Molecular Neurobiology.
[2] Jing Wang,et al. Cardioprotective effects of gypenoside XVII against ischemia/reperfusion injury: Role of endoplasmic reticulum stress, autophagy, and mitochondrial fusion fission balance , 2022, Phytotherapy research : PTR.
[3] Peng Kong,et al. Inflammation and atherosclerosis: signaling pathways and therapeutic intervention , 2022, Signal Transduction and Targeted Therapy.
[4] Jian-ping Luo,et al. Laminaria japonica Polysaccharide Suppresses Atherosclerosis via Regulating Autophagy-Mediated Macrophage Polarization. , 2022, Journal of agricultural and food chemistry.
[5] J. Björkegren,et al. Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype , 2021, The Journal of clinical investigation.
[6] T. Sun,et al. Gypenoside XVII protects against spinal cord injury in mice by regulating the microRNA-21-mediated PTEN/AKT/mTOR pathway , 2021, International journal of molecular medicine.
[7] Guanwei Fan,et al. Astragalus Flavone Ameliorates Atherosclerosis and Hepatic Steatosis Via Inhibiting Lipid-Disorder and Inflammation in apoE−/− Mice , 2020, Frontiers in Pharmacology.
[8] Xiao-Hua Yu,et al. LncRNA kcnq1ot1 promotes lipid accumulation and accelerates atherosclerosis via functioning as a ceRNA through the miR-452-3p/HDAC3/ABCA1 axis , 2020, Cell Death & Disease.
[9] Xiao-Hua Yu,et al. Biochanin A Mitigates Atherosclerosis by Inhibiting Lipid Accumulation and Inflammatory Response , 2020, Oxidative medicine and cellular longevity.
[10] W. Shen,et al. Gypenosides improves nonalcoholic fatty liver disease induced by high-fat diet induced through regulating LPS/TLR4 signaling pathway , 2020, Cell cycle.
[11] Jia Wen Liang,et al. A novel long noncoding RNA, LOC440173, promotes the progression of esophageal squamous cell carcinoma by modulating the miR‐30d‐5p/HDAC9 axis and the epithelial–mesenchymal transition , 2020, Molecular carcinogenesis.
[12] Shujuan Sun,et al. The synergistic antifungal effects of gypenosides combined with fluconazole against resistant Candida albicans via inhibiting the drug efflux and biofilm formation. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[13] Dayuan Li,et al. MiR-182-5p Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by ox-LDL Through Targeting PAPPA. , 2020, International heart journal.
[14] Zhiwei Wu,et al. Enhancing PPARγ by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice. , 2020, Pharmacological research.
[15] Minakshi Rana,et al. Role of pyruvate kinase M2 in oxidized LDL-induced macrophage foam cell formation and inflammation[S] , 2020, Journal of Lipid Research.
[16] X. Shu,et al. Gypenosides mediate cholesterol efflux and suppress oxidized LDL induced inflammation in retinal pigment epithelium cells. , 2020, Experimental eye research.
[17] Liping Chang,et al. Gypenoside A protects ischemia/reperfusion injuries by suppressing miR-143-3p level via the activation of AMPK/Foxo1 pathway. , 2019, BioFactors.
[18] Xingxing Li,et al. Butyrate protects against high‐fat diet‐induced atherosclerosis via up‐regulating ABCA1 expression in apolipoprotein E‐deficiency mice , 2019, British journal of pharmacology.
[19] Tessa J. Barrett. Macrophages in Atherosclerosis Regression , 2019, Arteriosclerosis, thrombosis, and vascular biology.
[20] Guibo Sun,et al. Gypenoside XVII protects against myocardial ischemia and reperfusion injury by inhibiting ER stress–induced mitochondrial injury , 2019, Journal of ginseng research.
[21] Changsheng Yan,et al. Gypenosides improve the intestinal microbiota of non-alcoholic fatty liver in mice and alleviate its progression. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[22] Tae Young Kim,et al. Gynostemma Pentaphyllum Extract Ameliorates High-Fat Diet-Induced Obesity in C57BL/6N Mice by Upregulating SIRT1 , 2019, Nutrients.
[23] Xi-Long Zheng,et al. Krüppel-like factor 14 inhibits atherosclerosis via mir-27a-mediated down-regulation of lipoprotein lipase expression in vivo. , 2019, Atherosclerosis.
[24] P. Libby,et al. Atherosclerosis , 2019, Nature Reviews Disease Primers.
[25] Ling-Ping Zhu,et al. Circulating miR-182-5p and miR-5187-5p as biomarkers for the diagnosis of unprotected left main coronary artery disease. , 2019, Journal of thoracic disease.
[26] D. Tang,et al. Research Progress on the Relationship between Atherosclerosis and Inflammation , 2018, Biomolecules.
[27] Weiwei Jiang,et al. miR-182-5p Attenuates High-Fat -Diet-Induced Nonalcoholic Steatohepatitis in Mice. , 2018, Annals of hepatology.
[28] Jun Zhang,et al. Gypenosides improve diabetic cardiomyopathy by inhibiting ROS‐mediated NLRP3 inflammasome activation , 2018, Journal of cellular and molecular medicine.
[29] Ping Li,et al. Tanshindiol C inhibits oxidized low-density lipoprotein induced macrophage foam cell formation via a peroxiredoxin 1 dependent pathway. , 2018, Biochimica et biophysica acta. Molecular basis of disease.
[30] Li-Tao Yi,et al. miR-124 antagonizes the antidepressant-like effects of standardized gypenosides in mice , 2018, Journal of psychopharmacology.
[31] A. Orekhov,et al. Mechanisms of foam cell formation in atherosclerosis , 2017, Journal of Molecular Medicine.
[32] Guibo Sun,et al. Gypenoside XVII Prevents Atherosclerosis by Attenuating Endothelial Apoptosis and Oxidative Stress: Insight into the ERα-Mediated PI3K/Akt Pathway , 2017, International journal of molecular sciences.
[33] A. Orekhov,et al. Macrophage phenotypic plasticity in atherosclerosis: The associated features and the peculiarities of the expression of inflammatory genes. , 2015, International journal of cardiology.
[34] G. Zhan,et al. Mechanism of action of gypenosides on type 2 diabetes and non-alcoholic fatty liver disease in rats. , 2015, World journal of gastroenterology.
[35] A. Tall,et al. Cholesterol, inflammation and innate immunity , 2015, Nature Reviews Immunology.
[36] J. Repa,et al. Histone Deacetylase 9 Represses Cholesterol Efflux and Alternatively Activated Macrophages in Atherosclerosis Development , 2014, Arteriosclerosis, thrombosis, and vascular biology.
[37] Jonathan D. Smith. New role for histone deacetylase 9 in atherosclerosis and inflammation. , 2014, Arteriosclerosis, thrombosis, and vascular biology.
[38] Z. Qin,et al. The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature. , 2012, Atherosclerosis.
[39] Mudit Gupta,et al. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. , 2011, Cell stem cell.
[40] M. Turunen,et al. Silencing of either SR-A or CD36 reduces atherosclerosis in hyperlipidaemic mice and reveals reciprocal upregulation of these receptors. , 2010, Cardiovascular research.
[41] D. Rader,et al. The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis This work was supported by P01-HL22633 from the NHLBI. Published, JLR Papers in Press, December 8, 2008. , 2009, Journal of Lipid Research.
[42] Heather M. Alger,et al. Inhibition of Stearoyl-Coenzyme A Desaturase 1 Dissociates Insulin Resistance and Obesity From Atherosclerosis , 2008, Circulation.
[43] Paul T. Tarr,et al. ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation. , 2005, Cell metabolism.
[44] Robert V Farese,et al. Plasma Cholesteryl Esters Provided by Lecithin:Cholesterol Acyltransferase and Acyl-Coenzyme A:Cholesterol Acyltransferase 2 Have Opposite Atherosclerotic Potential , 2004, Circulation research.
[45] E. Olson,et al. Histone Deacetylases 5 and 9 Govern Responsiveness of the Heart to a Subset of Stress Signals and Play Redundant Roles in Heart Development , 2004, Molecular and Cellular Biology.
[46] J. Oram,et al. Molecular basis of cholesterol homeostasis: lessons from Tangier disease and ABCA1. , 2002, Trends in molecular medicine.
[47] K. Bornfeldt,et al. Cyclic AMP-specific phosphodiesterase 4 inhibitors promote ABCA1 expression and cholesterol efflux. , 2002, Biochemical and biophysical research communications.
[48] D. Shiffman,et al. Oxidized Low Density Lipoprotein Exposure Alters the Transcriptional Response of Macrophages to Inflammatory Stimulus* , 2001, The Journal of Biological Chemistry.
[49] M. Grunstein. Histone acetylation in chromatin structure and transcription , 1997, Nature.
[50] S. Daskalopoulou,et al. Adiponectin and cholesterol efflux. , 2019, Metabolism: clinical and experimental.
[51] P. Murray. Macrophage Polarization. , 2017, Annual review of physiology.
[52] B. Staels,et al. Macrophage subsets in atherosclerosis , 2015, Nature Reviews Cardiology.
[53] E. Olson,et al. The many roles of histone deacetylases in development and physiology: implications for disease and therapy , 2009, Nature Reviews Genetics.
[54] I. Adcock,et al. Histone acetylation and histone deacetylation , 2002, Molecular biotechnology.