Electrophilic and Drug-Induced Stimulation of NOTCH3 N-terminal Fragment Oligomerization in Cerebrovascular Pathology

[1]  R. Valera,et al.  Adverse Effects Associated with Proton Pump Inhibitor Use , 2021, Cureus.

[2]  J. de Batlle,et al.  Proton pump inhibitors and the risk of Alzheimer’s disease and non-Alzheimer’s dementias , 2020, Scientific Reports.

[3]  Michael M. Wang,et al.  Binding of omeprazole to protein targets identified by monoclonal antibodies , 2020, PloS one.

[4]  R. Lyons,et al.  Proton pump inhibitors and dementia risk: Evidence from a cohort study using linked routinely collected national health data in Wales, UK , 2020, PloS one.

[5]  A. Saykin,et al.  Broad phenotype of cysteine-altering NOTCH3 variants in UK Biobank , 2020, Neurology.

[6]  Prateek Sharma,et al.  Proton pump inhibitors do not increase the risk of dementia: a systematic review and meta-analysis of prospective studies. , 2020, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

[7]  M. Ivanova,et al.  Thiol-mediated and catecholamine-enhanced multimerization of a cerebrovascular disease enriched fragment of NOTCH3 , 2020, Experimental Neurology.

[8]  Michael M. Wang,et al.  NOTCH3 is non-enzymatically fragmented in inherited cerebral small-vessel disease , 2020, The Journal of Biological Chemistry.

[9]  Yi-Chung Lee,et al.  NOTCH3 cysteine-altering variant is an important risk factor for stroke in the Taiwanese population , 2019, Neurology.

[10]  T. Toda,et al.  Wide distribution of alpha-synuclein oligomers in multiple system atrophy brain detected by proximity ligation , 2019, Acta Neuropathologica.

[11]  J. Alegre-Abarrategui,et al.  Alpha-Synuclein Proximity Ligation Assay (AS-PLA) in Brain Sections to Probe for Alpha-Synuclein Oligomers. , 2019, Methods in molecular biology.

[12]  D. Liew,et al.  Dementia, cognitive impairment and proton pump inhibitor therapy: A systematic review , 2017, Journal of gastroenterology and hepatology.

[13]  Li-ping Zhu,et al.  Hierarchical Self‐Assembly of Dopamine into Patterned Structures , 2017 .

[14]  Zhao Lei,et al.  Effect of N-Ethylmaleimide as a Blocker of Disulfide Crosslinks Formation on the Alkali-Cold Gelation of Whey Proteins , 2016, PloS one.

[15]  Trushar R. Patel,et al.  Dynamic light scattering: a practical guide and applications in biomedical sciences , 2016, Biophysical Reviews.

[16]  J. van der Grond,et al.  Archetypal NOTCH3 mutations frequent in public exome: implications for CADASIL , 2016, Annals of clinical and translational neurology.

[17]  P. Zhou,et al.  A thiol-thiosulfonate reaction providing a novel strategy for turn-on thiol sensing. , 2015, Chemical communications.

[18]  A. Rogowska-Wrzesińska,et al.  Differential alkylation-based redox proteomics – Lessons learnt , 2015, Redox biology.

[19]  Å. Wallén-Mackenzie,et al.  In Situ Proximity Ligation Assay (PLA). , 2015, Methods in molecular biology.

[20]  Michael M. Wang,et al.  von Willebrand Factor Permeates Small Vessels in CADASIL and Inhibits Smooth Muscle Gene Expression , 2012, Translational Stroke Research.

[21]  Michael M. Wang.  Notch signaling and Notch signaling modifiers. , 2011, The international journal of biochemistry & cell biology.

[22]  E. Kremmer,et al.  Co-aggregate formation of CADASIL-mutant NOTCH3: a single-particle analysis. , 2011, Human molecular genetics.

[23]  M. Dichgans,et al.  CADASIL mutations enhance spontaneous multimerization of NOTCH3. , 2009, Human molecular genetics.

[24]  M. Viitanen,et al.  Different Clinical Phenotypes in Monozygotic CADASIL Twins With a Novel NOTCH3 Mutation , 2009, Stroke.

[25]  G. Sachs,et al.  Chemistry of covalent inhibition of the gastric (H+, K+)-ATPase by proton pump inhibitors. , 2004, Journal of the American Chemical Society.

[26]  Peter T. Lansbury,et al.  Kinetic Stabilization of the α-Synuclein Protofibril by a Dopamine-α-Synuclein Adduct , 2001, Science.

[27]  R. N. Brogden,et al.  Fenoldopam: a review of its pharmacodynamic and pharmacokinetic properties and intravenous clinical potential in the management of hypertensive urgencies and emergencies. , 1997, Drugs.

[28]  J. Hoekstra,et al.  Fenoldopam Review of its Pharmacodynamic and Pharmacokinetic Properties and Intravenous Clinical Potential in the Management of Hypertensive Urgencies and Emergencies , 1997 .

[29]  J. Weissenbach,et al.  Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia , 1996, Nature.

[30]  W. Linert,et al.  Anaerobic oxidation of cysteine to cystine by iron(III). Part 1. The reaction in acidic solution , 1988 .

[31]  Fujita Keisuke,et al.  Conjugation of dopa and 5-S-cysteinyldopa with cysteine mediated by superoxide radical. , 1982 .

[32]  K. Fujita,et al.  Conjugation of dopa and 5-S-cysteinyldopa with cysteine mediated by superoxide radical. , 1982, Biochemical pharmacology.